THE MEDICAL TREATMENT OF CANCER.

THE MEDICAL TREATMENT OF CANCER.

667 CORRESPONDENCE POSTURE IN HEALTH AND DISEASE. To the Editor of THE LANCET. preparation. This particular investigations have taken." is the line...

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667

CORRESPONDENCE POSTURE IN HEALTH AND DISEASE. To the Editor of THE LANCET.

preparation. This particular investigations have taken."

is the line

our

own

clinical

[It

was not in respect of this letter that Dr. Todd wrote to me, but in connexion with what occurred in London in 1928,

I and

SIR,—May I return to your reportof an address I shall quote what I then said about Dr. Todd directly.]] this subject recently given by Miss M. ForresterIn any case it would be puerile for us, who have Brown to the London Association of the Medical made and tested some hundreds of Women’s Federation. This report interested me of lead colloids to claim any priority greatly, but in view of the conclusions arrived at by preparations that of the use of colloidal lead and colloidal I beyond no less a scientist than the late Rudolph Magnus, am surprised to note that it attributed to Misslead compounds in general for the treatment of cancer. Forrester-Brown the following statement: " The ’However, for the information of Dr. Todd I may say we commenced the manufacture of lead selenide position of the head is relatively unimportant in that in October, 1926, and in a private report dated with for the reflex motor connexion good posture, Jan. from Prof. Lewis’s laboratory for 10th, 1927, is at the are horizontal." peace provided system eyes Now Magnus, after 14 years’ experimentation,circulation among the staff of the Liverpool Medical arrived at the opposite conclusion, and the details. Research Organisation, the preface to the description of his work are available to all of us through your of the preparation of this compound contains the columns.2 It is significant that Sir Charles Sherrington words :... it was thought by the clinical workers that a made the " central control " discovery of Magnus the of this element with lead might repay compound subject of a speech when President of the Royal clinical investigation... [selenium] As far as is known a colloidal the of in health and solution of this compound has not been prepared before, and Society. As subject posture details are therefore recorded." disease is of vital importance to every doctor, and as Miss Forrester-Brown has indirectly thrown out a theWe found, as I have said before, that this preparachallenge to Magnus and put a shadow of doubt into tion is of little value in comparison with other preparaour minds, may I ask her to give us details of the tions. I give the above quotation to show that in scientific experimentation which has led her to the the circumstances I was not ungenerous when I very opposite conclusion to that which was reached subsequently published at Dr. Todd’s request in the by Magnus British Medical Journal (July 7th, 1928, p. 35) the I am, Sir, yours faithfully, following remark in support of his claim to have M. DOUGLAS, M.B. Bolton, Sept. llth, 1930. worked independently in this connexion:on

I progressively

"

"... the work at Bristol, although based

THE MEDICAL TREATMENT OF CANCER.

THE LANCET. difficult to express oneself really very in I not feel the least degree do politely, although acrimonious, when one has to deal with statements such as those of Dr. Todd, for they have their origin in scientific ignorance, verbal inaccuracy, and gross misrepresentation. These are capital offences from an intellectual point of view ; and, as with all capital offences, they must be expiated. Moreover, Dr. Todd has advanced no extenuating circumstances to account for his failings : indeed, in his present letter (THE LANCET, Sept. 13th, p. 611) he makes matters worse. With regard to his reference to the correspondence that has taken place in respect of his claim for priority in the use of lead selenide in the treatment of cancer, you would not have space for the private letters, much as I should like to publish them ; I will, therefore, simply quote a short letter that I wrote to you on March 19th, 1927, a week after Dr. Todd’s first note (THE LANCET, March 12th, 1927). The letter runs :To the Editor

of

work in

why in his present letter Dr. Todd says " that the system as described [by Dr. Todd] has been originated

SIR,-It is

here from the work of others and ourselves and owes nothing more to him [W. B. B.]," in view of the fact that he commences his first publication (THE LANCET, March 12th, 1927, p. 575) with the following words :The article published by Prof. Blair Bell on the action of colloidal lead on cancer (THE LANCET, 1925, -ii., 793) suggested independent research." His second communication (" Chemotherapeutic on Cancer," Arrowsmith, 1928) starts in a similar fashion :"

Researches

results of the action of colloidal lead claimed by Prof. Blair Bell in his article of 1925 determined me to experiment independently, a part of the attraction being a study of the resultant blood changes. We all know the results of his treatment now, but at the time stated proofs were not nearly so complete. The results themselves ... encouraged the hope that colloidal lead would be of use." [Of course, our first publication, never mentioned as far as I know by Dr. Todd, appeared in 1922.]

" The

promising

on cancer

Sir, finding acknowledgments fatal BhisNow, pretentions, Dr. Todd has shifted his ground,

" I have been interested in the brief account by Dr. A. T. Todd of the initial results obtained in some of the cases of malignant disease treated by him with " lead-selenium colloid(THE LANCET, March 12th, 1927, p. 575). The possibilities of a combination of these elements occurred to me, and doubtless to many others, long ago ; and, as a matter of fact, our physical chemists had no difficulty in making an excellent colloid of lead selenide. But what will ultimately prove to be the most useful preparation of lead no one can foretell at the present time. Since many preparations of lead will probably be found to affect to a greater or lesser degree malignant neoplasms, what are really needed are comparative studies in regard to a large number of combinations rather than isolated observations of one

I

1 THE LANCET, 1930, i., 32. 2 THE LANCET, 1926, ii., 531 and 585.

on our

Liverpool, has been conducted entirely independently ..." I should like to inquire in this connexion exactly

these

to or

rather turned a complete somersault. He now states that in the treatment of cancer with lead selenide the lead is inert and is merely used by him " as a vehicle for selenium " (!) I confess that such an astounding assertion paralyses my powers of commentation. Is it necessary to add that selenium was extensively tried in the treatment of cancer and found wanting, long Dr. Todd took it up? Why did Dr. Todd not immediately write dissociating himself from the views expressed in your leading article (THE LANCET, 23rd, p. 406), where you clearly attribute his to lead

before

August

results

668 The interesting announcement that Dr. Todd intends MEDICAL NEWS to give up lead in the treatment of cancer in favour, I suppose, of selenium, already discredited, should be noted by those who imagine that patients .are Post-graduate Courses in Berlin. Besides the regular programme of post-graduate study treated in Bristol by the method introduced by us. a series of special courses are being held in Berlin during the I am, Sir, yours faithfully, autumn. The subjects include laboratory work (Sept. 29th to Oct. 4th), internal medicine (Oct. 6th to 18th), children’s W. BLAIR BELL. Liverpool, Sept. 13th, 1930. 1st to the 29th to Oct.

Ilth), llth), eye (Oct. and throat (Oct. 13th to 25th), intrathoracic disease, especially tuberculosis (Oct. 20th to 24th), occupation and illness, with special consideration of assessment of Efficiency (Oct. 27th to Nov. 4th). The courses are held in German, but many of the lecturers speak English. Particulars may be had from the information bureau of the Kaiserin Friedrich-Haus (Berlin, N.W.6, Luisenplatz2), which offers help in procuring suitable lodgings and arranging attendance at clinics. Further courses will be held in the spring. diseases the ear,

SOCIETY.

RESEARCH DEFENCE

of THE LANCET. persuade more members

To the Editor

SIR,—I wish I could

of the

(Sept. nose

profession to be subscribers to the Research Society. We do not need any large A Course in Cardiology. sum, but if we could get two hundred more annual I Dr. C. Laubry will take charge of a course on Diseases subscribers of f1, it would make our work easier to of the Heart and Vessels to be held at the Hopital Broussais, carry on. We are the only society that exists to rue Didot, Paris, from Oct. 13th to 25th. Particulars are expose the mis-statements of the antivivisection obtainable from Dr. Mevel at the hospital. medical Defence

societies and agitators. They preach that all experiments on animals are useless, that no good has come from them to man or beast, and that the experiments An uninformed public accept such are grossly cruel. statements as true, and the only way to get the facts known is by the propaganda of a society such as ours. But this is expensive-and so I ask the help of those who wish it well. I am, Sir, yours faithfully,

of Orthopaedics. The Societe Française d’Orthopedie will hold its twelfth reunion at 9.30 A.M. on Friday, Oct. 10th, at the Faculty of Medicine (Amphitheatre Vulpian), Paris. The subjects of discussion will be Coxa Vara in Adolescents and Obstetrical Paralyses of the Upper Limb. The Secretary-general is Dr. E. Sorrel, 179, Boulevard Saint-Germain, Paris. Hygiene in the Tropics. Lectures and demonstrations for men and women, outside the medical profession, proceeding to the tropics, will be given at the London School of Hygiene and Tropical Medicine by Lieut.-Colonel G. E. F. Stammers, on Oct. 8th, 9th, 10th, 13th, 14th, 15th, 16th, and 17th, from 11 A.M. to 12.30 P.M.

Congress

KNUTSFORD, Chairman, Research Defence Society. 11, Chandos-street, Cavendish-square, London, W., Sept. 16th, 1930.

Medical Women’s Federation. The annual conference of the psychological section of this

Federation is to be held on Saturday, Oct. 18th, at The Lawn, Lincoln. Dr. Alice Hutchison will speak on Child Guidance in Relation to Juvenile Delinquency, and there will be an informal discussion on The Local Government Act and Mental Treatment Act, and how they affect the Treatment of Mental Disorder.

UNDESIGNATED PASTEURISED MILK.

To the Editor

of

THE LANCET.

SIR,—Dr. Duncan Forbes’s dictum, that the safest milk from the point of view of tuberculosis and sore-throat infections is pasteurised milk, will not be supported elsewhere in the country. Brighton is fortunate in possessing modern pasteurisation equipment. But in other parts of the country there is no doubt that inefficient pasteurisation apparatus still exists. I have recently come across cases of infantile diarrhcea that were reported to be fed on so-called pasteurised milk. Dr. W. G. Savage, in his recent authoritative work, has stressed the dangers of inefficient pasteurisation. This view was upheld by various veterinary surgeons in the discussion at the Royal Society of Medicine (THE LANCET, 1929, ii., 1205), who contended that so-called pasteurisation was making milk dangerous instead of safe for

Instruction for D.P.H. A three-months’ course of lectures and demonstrations on clinical practice and in hospital administration will be

liquid

consumption. I am, Sir, yours

faithfully, FRANK BODMAN.

Bristol, Sept. 10th, 1930.

given at the North-Eastern Hospital, St. Ann’s-road, Tottenham, London, N., by Dr. F. H. Thomson, Medical Superintendent, on Mondays and Wednesdays at 4.45 P.M. and alternate Saturdays at 11 A.M., from Oct. 1st. Application should be made to the Medical Officer of Health, London County Council, Public Health Department (Special Hospitals), Victoria Embankment, E.C. 4.

Fellowship of Medicine and Post-Graduate Medical Association. From Sept. 29th to Oct. llth, at the Metropolitan Hospital, Kingsland-road, E., there will be an all-day in medicine, surgery, and the special departments. The subjects of special courses in October are as follows: diseases of ear, nose, and throat (Oct. 6th to Nov. 1st), tropical medicine (Oct. 6th to 25th, all day) ; gynaecology, (Oct. 13th to 24th) ; diseases of children (Oct. 27th to Nov. 5th) ; and orthopaedies (Oct. 27th to Nov. 5th). There will also be evening courses in preparation for the M.R.C.P. examination (17 lectures on Tuesdays and Fridays), and for the Final F.R.C.S. examination (six demonstrations on Particulars and syllabuses of all courses Wednesdays). at may be obtained from the Secretary of the 1, Wimpole-street, London, W. Ben Ulster Hospital. The annual report of this eye, ear, and throat hospital at Belfast states that last year 785 in-patients were admitted; new out-patients numbered 6390. The constant growth in the number of patients has necessitated additions and alterations, and the old female ward has been converted into private wards. During the year there were 1022 operations, 29 of them for cataract. Staffordshire General Infirmary. The 1549 in-patients last year stayed on an average 15days, half a day less than in 1928, and their cost, less Of an estimated amount for out-patients, was £6 5s. 6d. the 2113 out-patients half were ophthalmic (628) or nose, throat and ears (463) cases. The ordinary income, £8798, was the largest on record. course

’,

Fellowship

INDUSTRIAL TRAINING

TUBERCULOUS.The committee of management of Peamount Sanatorium, Co. Dublin, has established a system of industrial training FOR

THE

for tuberculous patients as a step toward the setting-up of a village settlement on lines similar to that at Papworth. The department of Local Government and Public Health of the Irish Free State, has, it is understood, promised its consent to the payment by Boards of Health of certain fees on behalf of patients undergoing training. The Peamount committee states that 31 patients are receivingindustrialtraining with a view to permanent employment by the Peamount Industries. Goods are produced and sold on an economic basis. The ultimate aim is to provide a village settlement for the tuberculous of the Free State, and Dr. P. C. Varrier-Jones, the founder and medical director of Papworth, has undertaken to supervise its

development.