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THE PATHOLOGY OF GIGANTISM.
747 of water really required for irrigation, washing, or other purposes are treated once a week with kerosine oil for the destruction of larvse; (5) that the surface and rain-water drainage of the premises is good and that the drains and roof-pipes are in proper repair; (6) that the latrines are in good condition and well kept; (7) that the drinking water is obtained and stored in a cleanly manner.
The school also intends to arrange courses of lectures on the prevention of tropical diseases, to be attended by clerks, missionaries, and others, both male and female, not in the medical profession, proceeding to West Africa and other tropical countries. Each course will consist of five lectures extending over two weeks, in the months of January, May, and November. Particulars may be obtained from the honorary secretary of the school, Mr. A. H. Milne, B 10,
Exchange buildings, Liverpool. THE
DISTRIBUTION
OF
PLAGUE.
I
infiltrate the latter. "The pituitary tumour," add Dr. Lannois and Dr. Roy, " explains at once the gigantism, the acromegaly, and the diabetes." Another feature of interest was the enlarged thyroid gland which weighed 250 grammes, or ten times the normal weight-a condition which has been termed ’compensatory hypertrophy " and which has been regarded by most observers as in some way associated with the destruction of the pituitary body. Such a hypertrophy of the thyroid has been noted in 13 out of 34 cases of acromegaly collected and published by Dr. G. Hinsdale of New York in 1898. There was also in the present caser evidence of tuberculosis at the apex of the left lung. Dilatation of the sella turcica had been noticed in the skulls of giants by Tartuffi in 1877, and in a memoir on the skull and skeleton of the Irish giant MacGrath Proft ssor D. J. (Cunningham pointed out (1891) that a similar condition ... was present and that the bones also showed evidences. of acromegaly. Gigantism and acromegaly are now known C t to be closely related conditions, and Dr. Lannois and I Dr. Roy conclude that they are both phases of a morbid of bodily nutrition due to a lesion of the pituitary 1 process 1body.
As regards the Cape Colony the medical officer of health of the Colony states that for the week ending Feb. 14th 5 cases of plague were discovered at Port Elizabeth, 1 being a Earopein male, 1 a Malay male, and 3 native males, 2 of the latter being found dead. The cases were discovered on the following dates: 2 on the 8th, 1 on the 9th, 1 on At the end of the week 10th, and 1 on the 12th. 3 cases remained under treatment at the Plague Hospital, DREAM-FAITH. Port Elizabeth. Plague-infected rats continued to be found Also at in the town of Port Elizabeth during the week. THE recent sad case of drowning at Shanklin with the Graff Reinet plague-infected rats and mice were found during sensational E evidence given at the inquest by a fisherman’s the week ended Feb. 14th. No case of plague has beenwife ... who found the corpse, will be treasured with avidity discovered in any other place in the colony. As regards no I doubt by large numbers of persons. Amongst all Egypt the Director-General of the Sanitary Department Cclasses there are to be found plenty of individuals whodeg; states that since Feb. 6th no cases of, or deaths from, plague&’’ believe in dreams " and a larger number still who, though have occurred throughout Egypt. The 3 cases that were not I prepared to affirm their actual belief, yet think that under treatment have been discharged from hospital probably there is "something in them." These people hold, I recovered. i in fact, that mere coincidence will not account for such ( as that to which we are referring. It will beoccurrences THE PATHOLOGY OF GIGANTISM. remembered that the bodv of the unfortunate Miss I was found upon the rocks by a woman who IN the Revue Nenrologique of Jan. 31st Dr. P. E. Lumsden Lannois and Dr. Pierre Roy give an account of the patho- sstated at the inquest that she was led to search logical observations made post mortem on the French tthis spot by having on three successive nights dreamed t she saw there the corpse of the missing lady. Such a gianr, P- K-, whose height was 2-12 metres that s is at once enough to convince the believer in statement feet and who died from cerebral 11 inches), (6 recently d It fulfils at a breath all his hopes and carries outtumour in a hospital in Paris at the age of 36 years. It dreams. t the full visionary aspirations which perhaps he has is stated that at the age of 18 years he had nearly attained to his full stature. An interesting discussion is given con- a approached hitherto but has never seen definitely realised. Z To such people it would be vain to ask how many other in this case and cerning the clinical features observed f wives in and about Skanklin dreamed of the their correspondence with the post-mortem findings and thefishermen’s u conclusion is reached that the gigantic stature in this caseunhappy lady lying cold and dead upon the rocks. f: was due to acromegaly. investigation of the foundation of their creed is not Thus, in the year 1900 the patient Scientific f for dream-believers, and though in a hundred cases the same showed distinct signs of this condition, the lower jaws being 6 were to occur-as it probably did in this instancethen abnormally enlarged and elongated, the tongue and dream tto different people the ninety-nine where it proves false are nose being hypertrophied, and the hands appearing huge and in the jubilant acceptance of the one case where i; spade-like. A marked degree of glycosuria developed at ignored this stage, and at the same time he began to suffer much tthe dream coincided with the facts. Generally speaking, i the enormous numbers of dreams, the thousands from praecordial pain, palpitation, and paroxysmal attacks indeed, r that never, so to speak, " come off," are entirely like those of angina pectoris. As the glycosuria progressed nightly ecirc; in the presence of the one that hits off the facts emaciation set in, and a steadily progressing hebetude &disregarded -or at made itself manifest. Occasional epileptiform convulsions any rate appears to do so afterwards. For, with occurred which led to the suspicion of cerebral tumour, and aall the honesty in the world, the imagination of a poor ’i dwelling by the sea, fostered as are the imaginaowing to the associated condition of acromegaly being presentwoman it was possible to diagnose the tumour as being one of the ttions of a sea-shore folk by the winds and waves and pituitary body. The patient died during one of his fits and ssuggestive sights and sounds of the waters, is flexible to the necropsy revealed the following conditions. The cranial tthe extreme and readily takes for true what suits its bones were much thickened and the sella turcica orrnatural trend. The very number of times that the dream pituitary fossa was found to be enlarged and occupied by a coccurred is suggestive. Three is the favoured numeral of tumour of the size of a large Barcelona nut, measuring tthe superstitious and we can quite believe that if this fisherhad but dreamed her dream on two occasions, or ... one and three-fifths of an inch transversely. The growthwife extended into the right lateral ventricle of the brain anda night or two apart, these would have welded themalso projected forwards slightly between the fronto-orbital Eselves in her imagination into three successive nights. r natural desire of humanity for communication with the gyri. It was a primary epithelioma of the anterior lobe The E has been a feature of the human race ever of the pituitary body, its outline was well defined, andsupernatural E the earliest times of which we have any record. although it pressed upon the brain substance it did notsince
the
------
____
The school also intends to arrange courses of lectures on the prevention of tropical diseases, to be attended by clerks, missionaries, and others, both male and female, not in the medical profession, proceeding to West Africa and other tropical countries. Each course will consist of five lectures extending over two weeks, in the months of January, May, and November. Particulars may be obtained from the honorary secretary of the school, Mr. A. H. Milne, B 10,
Exchange buildings, Liverpool. THE
DISTRIBUTION
OF
PLAGUE.
I
infiltrate the latter. "The pituitary tumour," add Dr. Lannois and Dr. Roy, " explains at once the gigantism, the acromegaly, and the diabetes." Another feature of interest was the enlarged thyroid gland which weighed 250 grammes, or ten times the normal weight-a condition which has been termed ’compensatory hypertrophy " and which has been regarded by most observers as in some way associated with the destruction of the pituitary body. Such a hypertrophy of the thyroid has been noted in 13 out of 34 cases of acromegaly collected and published by Dr. G. Hinsdale of New York in 1898. There was also in the present caser evidence of tuberculosis at the apex of the left lung. Dilatation of the sella turcica had been noticed in the skulls of giants by Tartuffi in 1877, and in a memoir on the skull and skeleton of the Irish giant MacGrath Proft ssor D. J. (Cunningham pointed out (1891) that a similar condition ... was present and that the bones also showed evidences. of acromegaly. Gigantism and acromegaly are now known C t to be closely related conditions, and Dr. Lannois and I Dr. Roy conclude that they are both phases of a morbid of bodily nutrition due to a lesion of the pituitary 1 process 1body.
As regards the Cape Colony the medical officer of health of the Colony states that for the week ending Feb. 14th 5 cases of plague were discovered at Port Elizabeth, 1 being a Earopein male, 1 a Malay male, and 3 native males, 2 of the latter being found dead. The cases were discovered on the following dates: 2 on the 8th, 1 on the 9th, 1 on At the end of the week 10th, and 1 on the 12th. 3 cases remained under treatment at the Plague Hospital, DREAM-FAITH. Port Elizabeth. Plague-infected rats continued to be found Also at in the town of Port Elizabeth during the week. THE recent sad case of drowning at Shanklin with the Graff Reinet plague-infected rats and mice were found during sensational E evidence given at the inquest by a fisherman’s the week ended Feb. 14th. No case of plague has beenwife ... who found the corpse, will be treasured with avidity discovered in any other place in the colony. As regards no I doubt by large numbers of persons. Amongst all Egypt the Director-General of the Sanitary Department Cclasses there are to be found plenty of individuals whodeg; states that since Feb. 6th no cases of, or deaths from, plague&’’ believe in dreams " and a larger number still who, though have occurred throughout Egypt. The 3 cases that were not I prepared to affirm their actual belief, yet think that under treatment have been discharged from hospital probably there is "something in them." These people hold, I recovered. i in fact, that mere coincidence will not account for such ( as that to which we are referring. It will beoccurrences THE PATHOLOGY OF GIGANTISM. remembered that the bodv of the unfortunate Miss I was found upon the rocks by a woman who IN the Revue Nenrologique of Jan. 31st Dr. P. E. Lumsden Lannois and Dr. Pierre Roy give an account of the patho- sstated at the inquest that she was led to search logical observations made post mortem on the French tthis spot by having on three successive nights dreamed t she saw there the corpse of the missing lady. Such a gianr, P- K-, whose height was 2-12 metres that s is at once enough to convince the believer in statement feet and who died from cerebral 11 inches), (6 recently d It fulfils at a breath all his hopes and carries outtumour in a hospital in Paris at the age of 36 years. It dreams. t the full visionary aspirations which perhaps he has is stated that at the age of 18 years he had nearly attained to his full stature. An interesting discussion is given con- a approached hitherto but has never seen definitely realised. Z To such people it would be vain to ask how many other in this case and cerning the clinical features observed f wives in and about Skanklin dreamed of the their correspondence with the post-mortem findings and thefishermen’s u conclusion is reached that the gigantic stature in this caseunhappy lady lying cold and dead upon the rocks. f: was due to acromegaly. investigation of the foundation of their creed is not Thus, in the year 1900 the patient Scientific f for dream-believers, and though in a hundred cases the same showed distinct signs of this condition, the lower jaws being 6 were to occur-as it probably did in this instancethen abnormally enlarged and elongated, the tongue and dream tto different people the ninety-nine where it proves false are nose being hypertrophied, and the hands appearing huge and in the jubilant acceptance of the one case where i; spade-like. A marked degree of glycosuria developed at ignored this stage, and at the same time he began to suffer much tthe dream coincided with the facts. Generally speaking, i the enormous numbers of dreams, the thousands from praecordial pain, palpitation, and paroxysmal attacks indeed, r that never, so to speak, " come off," are entirely like those of angina pectoris. As the glycosuria progressed nightly ecirc; in the presence of the one that hits off the facts emaciation set in, and a steadily progressing hebetude &disregarded -or at made itself manifest. Occasional epileptiform convulsions any rate appears to do so afterwards. For, with occurred which led to the suspicion of cerebral tumour, and aall the honesty in the world, the imagination of a poor ’i dwelling by the sea, fostered as are the imaginaowing to the associated condition of acromegaly being presentwoman it was possible to diagnose the tumour as being one of the ttions of a sea-shore folk by the winds and waves and pituitary body. The patient died during one of his fits and ssuggestive sights and sounds of the waters, is flexible to the necropsy revealed the following conditions. The cranial tthe extreme and readily takes for true what suits its bones were much thickened and the sella turcica orrnatural trend. The very number of times that the dream pituitary fossa was found to be enlarged and occupied by a coccurred is suggestive. Three is the favoured numeral of tumour of the size of a large Barcelona nut, measuring tthe superstitious and we can quite believe that if this fisherhad but dreamed her dream on two occasions, or ... one and three-fifths of an inch transversely. The growthwife extended into the right lateral ventricle of the brain anda night or two apart, these would have welded themalso projected forwards slightly between the fronto-orbital Eselves in her imagination into three successive nights. r natural desire of humanity for communication with the gyri. It was a primary epithelioma of the anterior lobe The E has been a feature of the human race ever of the pituitary body, its outline was well defined, andsupernatural E the earliest times of which we have any record. although it pressed upon the brain substance it did notsince
the
------
____