The peptides, vol. 8, chemistry, biology and medicine of neurohypophyseal hormones and their analogs

The peptides, vol. 8, chemistry, biology and medicine of neurohypophyseal hormones and their analogs

GENERAL AND COMPARATIVE ENDOCRINOLOGY 70,477482 (1988) BOOK REVIEWS Recent Progress in Hormone Research, Volume 43. Edited by J. H. CLARK. Academ...

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GENERAL

AND COMPARATIVE

ENDOCRINOLOGY

70,477482

(1988)

BOOK REVIEWS Recent Progress in Hormone Research, Volume 43. Edited by J. H. CLARK. Academic Press, Orlando, FL, 1987. 553 pp. $79.

As in previous volumes of this series, selected topics, 14 in all, were chosen as the formal program at the annual Laurentian Hormone Conference. The primary 14 presentations are collected in this volume, together with a highly edited version of the discussions that followed each of them. As might be expected, in view of the recent vigorous utilization of molecular techniques in endocrinology, several of the presentations deal with molecular mechanisms in the synthesis or the expression of action of hormones, including GnRH, gonadotropins, corticosteroids (and their receptors), mullerian inhibitory substance, catecholamines (and their receptors), prolactin, and growth hormone. Comparative endocrinologists may be especially interested in chapters on the mullerian inhibitory factor and one on the occurrence of proopiomelanocortin-derived peptides (MSH, endorphin) in rat gonadal and accessory sex organ tissues. Volume 43 is dedicated to Professor Roy 0. Greep, a most productive, original, and influential reproductive endocrinologist, and himself a student of F. L. Hisaw. Volume 43 is an excellent addition to this wellestablished series. Recent Advances in Adrenal Regulation and Function. Edited by R. D'AGATA AND G.P. CHROUSOS. Raven Press, New York, 1987. 332 pp. $62.

About one-third of this volume is devoted to basic topics and the remainder to clinical aspects of adrenal function. Chapters by Lowry and colleagues and by Chrousos et al. focus on CRF and other ACTHreleasing factors. An interesting chapter by Voutilainen and Miller deals with the hor-

monogenic enzymes that are common to the formation of the gonadal as well as the adrenal steroids. A chapter by Hyatt reviews the formation of the cellular zones of the mammalian adrenal cortex and the functional differentiation of these zones. Two chapters are concerned with adrenal androgen formation. Two chapters take up various phases of glucocorticoid receptors including their molecular features. The Peptides, Vol. 8, Chemistry, Biology and Medicine of Neurohypophyseal Hormones and Their Analogs. Edited by C. W. SMITH. Academic Press, San Diego, CA, 1987. 370 pp.

Well over one-third of this book is a highly detailed review of the biological activities of a very large number of chemical analogs of the natural hormones oxytocin, vasopressin, and vasotocin. The book opens with a brief anatomical review of the brain sources of the neurohypophyseal hormones and the clinical manifestations of their disfunction or abnormal secretion. There is an interesting chapter on the “other neurohypophyseal peptides” in which 15 peptides other than the classical and well-known hypothalamic octopeptides are discussed. The peptides are all of the major “other” known derivatives of proopiomelanocortin, as well as somatostatin, CRF, and some of the gut hormones. The primary sources of some of these in unclear. The remaining chapters review the actions of the neurohypophyseal peptides on central nervous function, on the kidney, and on the heart. The subject matter is almost completely confined to humans and other mammals. The Physiology of Reproduction, Vol. 1 and 2. Edited by E. KNOBIL AND J. D. NEILL. Raven Press, New York, 1988. 2633 pp. $290.

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477 001~6480/88 $1.50 Copyright 6 1988 by Academic Press, Inc. All rights of reproduction in any form reserved.