The surgical treatment of experimental coarctation (atresia) of the aorta

544

AMERICAN

HEART

JOURNiL

A., and Park, E. A.: The Surgical tion (Atresia) of the Aorta. Ann. Surg.

Blalock,

Treatment of Experimental 119: 445, 1914.

Coarcta-

These experiments were undertaken with the idea of devising a means for the surgical treatment of coarctation of the aorta. At a one-stage operation the thoracic aorta was divided, the two ends were closed, and the proximal end of the divided left subclavian artery was anastomosed to the side of the aorta beyond the point of its division. Some of the animals survived this procedure, and there was evidence of adequate blood flow to the posterior part of the body. The possible clinical application of these studies is discussed. AUTHORS.

Cooke, W. T., and Taylor, A. EL: Treatment of Subacute Infective With Heparin and Chemotherapy. Brit. Heart J. 5: 229, 1943. Five heparin.

patients were All died, and;

treated with combined in one, this was probably

chemotherapy due to the

Endocarditis

and intravenous heparin therapy.

Twenty patients (including the five treated with heparin) were studied under treatment with sulfonamide derivatives. Five were totally unresponsive; twelve were moderately controlled. Life was prolonged in some, but all eventually died. Three patients became apyrexial; one died after forty-five days of normal temperature, but, as there was no autopsy, neither the diagnosis nor the state of the lesion could be determined. A second died one year after the onset of his infection and eight months after the control of his pyrexia by sulfapyridine; autopsy showed healed lesions of infective endocarditis. The third is well and working at his occupation as a milk-roundsman at the present time, twelve months after his discharge from the hospital. Intravenous found, should

heparin did not prove of not be used in these cases.

value

in

our

cases

and,

as others

Prolonged chemotherapy offers a chance of cure to a few patients, great majority will not be so benefited. The dangers of such prolonged small and should not weigh against the chances of a successful outcome.

have

though therapy

the are

AUTHORS

McMillan, R. L.: Ventricular Tachycardia as a Therapeutic Thrombosis. South. %I. J. 36: 800, 1943. Ventricular tachycardia as a complication presented from the standpoint of etiology, ment, and prevention. Two cases with presented.

Problem

in Coronary

of severe myocardial disease has been pathologic physiology, diagnosis, treatsuccessful quinidine therapy have been AUTHOR.

Governale, S. L., and tion After Cardiac

Rink, A. G.: Arrest. Brit.

Spontaneous Renal M. J. 2: 43, 1944.

Apoplexy

With

Resuscita-

A case of spontaneous renal apoplexy due to malignant hypertensive eardiorenal disease has been presented. The patient’s heart stopped during operation. Cardiac resuscitation was accomplished by cardiac massage, intracardiac injecbion of stimulants, and intraventricular infusion of blood and saline. Life was restored for a period of eighteen hours after the operation. Death ensued from secondary or recurrent r,ight renal hemorrhage. Perusal of the literature does not disclose any previously reported case of intracardiac or intraventricular infusion. AUTHORS.