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The vitamin A content of human colostrum
LINETT
:
i:
CHORIONEPITHELIOMA
Tissue from tumor of posterior vaginal wall. Microscopic: The section consisted of organized blood clot within which were noted masses of banghans cells of varying size. These cells were palisaded or in alveolar formation. Hypertropic types and occasional mitotic figures suggest chorionepithelioma. On the day of admission the pat,ient had a free hemorrhage which necessitated packing. Hemoglobin 40 per cent; R.B.C. 2,176,OOO ; W.B.C. 6,800 ; polymorphonuSedimentation time seventy clear 61; lymphocytes 30. Blood pressure 90/60. minutes. Blood chemistry, Wassermann, and urine negative. On the day after admission patient was given 500 C.C. of blood by transfnsioa On December 9, R.B.C. 1,504,000, and hemoglobin 28 per cent. Patient received two more transfusions during her stay in the hospital. Roentgen ray studies of the lungs were negative for metastasis. The patient was subjected to two intensive x-ray treatments of the pelvis. Six rabbits were injected with patient’s urine in the following dilutions: 1. 2. 3. 4. 5. 6.
Injected Injected Injected Injected Injected Injected
with with with with with with
urine urine urine urine urine urine
in in in in in in
dilution dilution dilution dilution dilution dilution
1:20 1:40 1:80 1:160 1: 320 1:600
Both ovaries show multiple hemorrhagic Same Same One ovary shows one hemorrhagic cyst
cysts
Same
No hemorrhagic
cysti observed
The toxic condition of the patient and the anemia, gradually increa& until her death on Jan. 10, 1934, six weeks after her thirfl admission to the hospital. No postmortem was obtained. COMMENT
1. The anterior pituitary hormone reappeared in the urine after a negative test had been obtained. 2. A quantitative relationship between the concentration of the hormone in the urine and the proliferation of the tumor mass is shown. 3. Had this case been studied by the Aschheim-Zondek test, following the expulsion of the mole, proper therapeutic measures instituted early might have checked the progress of the condition. and
1 wish Rynd
to thank Mr. Yonke for carrying out on whose services the case occurred.
the
Friedman
Test
and
Drs.
Duncan
REFERENCES
(1) Roessler, H.: Ztschr. f. Geburtsh. u. Gynlk. 96: 516, 1929. (2) Castallo, A.: AM, J. OBST. & GYNEC. 26: 893, 1933. (3) Ehrhmdt, K.: Surg. Gynec. L.: Ax J. OBST. & GYNEC. 26: Obst. 63: 486, 1931. (4) Yazer, C., and Edeikem, 195, 1933. (5) Ma&, H. C., and Catherwod ,4. E.: AM. J. OBST. & GYNEC. 20: M.
670,
1930. 1474 PRESIDENT
Rep&t& M.: demograph.
STREET
The Vitamin A Content 31: 337, 1934.
of Human
Coloetrum,
Folia
gynaec*.-
The author’s experimental studies establish the fact that the vitamin A content. of colostrum is five times that of human milk. He concludes, because of that fact, it is important that the newborn be placed to the breast in the colostrum-excreting stage of lactation and makes a plea for a diet rich in vitamins during pregnancy and lactation. MARIO
A.
CASTAI,T.O.
:
i:
CHORIONEPITHELIOMA
Tissue from tumor of posterior vaginal wall. Microscopic: The section consisted of organized blood clot within which were noted masses of banghans cells of varying size. These cells were palisaded or in alveolar formation. Hypertropic types and occasional mitotic figures suggest chorionepithelioma. On the day of admission the pat,ient had a free hemorrhage which necessitated packing. Hemoglobin 40 per cent; R.B.C. 2,176,OOO ; W.B.C. 6,800 ; polymorphonuSedimentation time seventy clear 61; lymphocytes 30. Blood pressure 90/60. minutes. Blood chemistry, Wassermann, and urine negative. On the day after admission patient was given 500 C.C. of blood by transfnsioa On December 9, R.B.C. 1,504,000, and hemoglobin 28 per cent. Patient received two more transfusions during her stay in the hospital. Roentgen ray studies of the lungs were negative for metastasis. The patient was subjected to two intensive x-ray treatments of the pelvis. Six rabbits were injected with patient’s urine in the following dilutions: 1. 2. 3. 4. 5. 6.
Injected Injected Injected Injected Injected Injected
with with with with with with
urine urine urine urine urine urine
in in in in in in
dilution dilution dilution dilution dilution dilution
1:20 1:40 1:80 1:160 1: 320 1:600
Both ovaries show multiple hemorrhagic Same Same One ovary shows one hemorrhagic cyst
cysts
Same
No hemorrhagic
cysti observed
The toxic condition of the patient and the anemia, gradually increa& until her death on Jan. 10, 1934, six weeks after her thirfl admission to the hospital. No postmortem was obtained. COMMENT
1. The anterior pituitary hormone reappeared in the urine after a negative test had been obtained. 2. A quantitative relationship between the concentration of the hormone in the urine and the proliferation of the tumor mass is shown. 3. Had this case been studied by the Aschheim-Zondek test, following the expulsion of the mole, proper therapeutic measures instituted early might have checked the progress of the condition. and
1 wish Rynd
to thank Mr. Yonke for carrying out on whose services the case occurred.
the
Friedman
Test
and
Drs.
Duncan
REFERENCES
(1) Roessler, H.: Ztschr. f. Geburtsh. u. Gynlk. 96: 516, 1929. (2) Castallo, A.: AM, J. OBST. & GYNEC. 26: 893, 1933. (3) Ehrhmdt, K.: Surg. Gynec. L.: Ax J. OBST. & GYNEC. 26: Obst. 63: 486, 1931. (4) Yazer, C., and Edeikem, 195, 1933. (5) Ma&, H. C., and Catherwod ,4. E.: AM. J. OBST. & GYNEC. 20: M.
670,
1930. 1474 PRESIDENT
Rep&t& M.: demograph.
STREET
The Vitamin A Content 31: 337, 1934.
of Human
Coloetrum,
Folia
gynaec*.-
The author’s experimental studies establish the fact that the vitamin A content. of colostrum is five times that of human milk. He concludes, because of that fact, it is important that the newborn be placed to the breast in the colostrum-excreting stage of lactation and makes a plea for a diet rich in vitamins during pregnancy and lactation. MARIO
A.
CASTAI,T.O.