Three dimensional cortical surface morphometry and metabolism using registered magnetic resonance and position emission images

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MarylandPeychiatricRsearch center, P.O. Box 21247, Ehltimre, Maryland 21228 Byusingregistered highresolutionmagneticremname images(MRI)tc directearq?lingof&responding poeitmnemission toanosraphY(Pm P1ar-t the immhigator subebntially improveshis abilitytospecifythelocation andanatmi~'identityofhis~. ConventionalMIUdefinemst subcortical featuns clearly; they do nctpemitunambiguousidentification andrmwmmmkofthe surfaceanabny. Spcificgyriandsulciarenot readily classified fm any of the stanzard views (corcnal,sagittal, tz.mmmial). Herewedescribeam&hcdofdisplayitqarKI nbeasuringthe mxphologic and metabolic characteristicsof specific gyri. Quantitative assessmentSof sulcal volume are also easily delzermhd.