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Thyrophobia: how to overcome your fear of thyroid follicular tumours
Pathology (2012) 44(S1), pp. S9–S14
Anatomical, Oral and Maxillofacial Pathology including workshops
RCPA QUALITY ASSURANCE PROGRAM: REVIEW OF THE UROLOGY MODULE Fiona Maclean Douglass Hanly Moir Pathology, Urology Module Convener RCPA QAP, Sydney, NSW, Australia In the course of the presentation a review of the urology module of the Royal College of Pathologists of Australasia Quality Assurance Program (RCPA QAP) will be made, including an assessment of the results pertaining to straightforward urogenital cases, and those that presented more of a challenge to respondents. One aspect that will be examined in more depth is the range of responses given in regard to Gleason scoring of prostate adenocarcinoma, an area that has not been formally assessed to date but will be assessed going forward. Discussion will also be made concerning the performance monitoring project and the framework to be introduced in regard to anatomical pathology. THYROPHOBIA: HOW TO OVERCOME YOUR FEAR OF THYROID FOLLICULAR TUMOURS Jennifer L. Hunt Department of Pathology and Laboratory Medicine, University of Arkansas for Medical Sciences, Little Rock, AR, USA Thyroid follicular derived lesions are common in surgical pathology and range from non-neoplastic and inconsequential all the way to rare aggressive tumours. Unfortunately, the histological features can overlap substantially across this spectrum of diagnostic possibilities. The field of thyroid pathology is also notorious for being difficult for the pathologist, with reportedly high interobserver variability, challenging interpretations of reported criteria, and a lack of good ancillary diagnostic assays. For all these reasons (and more), the pathologist facing a thyroid follicular lesion may have to wade through anxiety-provoking differential diagnoses that impact directly on patient care and follow-up. This course will provide extensive illustrations and images to describe some of the standard and more subtle histological and cytological features of thyroid follicular tumours. The presentation will provide the pathologist with hints and tips for practical use in their every-day sign-out, and will review some of the ancillary testing that has been reported in the literature. MOLECULAR PATHOLOGY FOR THE ANATOMICAL PATHOLOGIST: A CASE BASED DISCUSSION Jennifer L. Hunt Department of Pathology and Laboratory Medicine, University of Arkansas for Medical Sciences, Little Rock, AR, USA The field of anatomical pathology is quickly moving from a descriptive science, where diagnoses were made based upon the visual clues present on the haematoxylin and eosin (H&E) stained Print ISSN 0031-3025/Online ISSN 1465-3931
#
glass slide, to being a much more comprehensive diagnostic specialty. In the new era of surgical and cytopathology, interpretation of disease will take into account the morphology, the protein expression profile, the underlying genomic changes, and other alterations and changes that fundamentally affect the cells. This combined approach to diagnostics can potentially enable better diagnoses, more refined prognostics, and can impact on therapeutic modalities that are selected. While the field is exploding with new biomarkers and molecular targets, pathologists continue to struggle with difficult questions. What molecular markers should I be considering for different tumour types? How should the results be interpreted in the context of the morphological findings? What role does that pathologist have in guiding treatment based upon the molecular profiling of disease? These questions, and more, will be answered in this case-based presentation of some selected lesions in anatomical pathology that have newly developing molecular implications. HOW I HANDLE BONE SPECIMENS: A CASE BASED PRESENTATION Michael Dray Waikato Hospital, Hamilton, New Zealand This practical talk covers a range of bone specimens handled and reported at Middlemore Hospital, the site of the New Zealand Bone and Soft Tissue Tumour Registry. A variety of techniques and approaches for the gross handling of the specimens and equipment is discussed. This includes dealing with a large limb amputation specimen, to a limb salvage specimen comprising a wide excision of bone and soft tissues, to smaller excision specimens, curettings of bony tissue and finally undecalcified bone specimens for quantitative histomorphometry. The use of band saws, desk top skill saws, and hand saws is illustrated. Principles of decalcifying bone are also discussed. Cases that have been selected to demonstrate this range of techniques include synovial chondrosarcoma, pleomorphic undifferentiated sarcoma, conventional osteosarcoma, post-radiation osteosarcoma, degenerative joint disease, osteomyelitis, and hypophosphatasia concurrent with renal bone disease. AN APPROACH TO LUCENT LESIONS OF BONE: A CASE BASED PRESENTATION WITH RADIOLOGICAL AND HISTOPATHOLOGICAL CORRELATION Michael Dray1, Clinton Pinto2 1 Waikato Hospital, Hamilton, and 2Middlemore Hospital, South Auckland, New Zealand This practical talk covers a range of bony lesions that are often initially characterised on plain radiographs. A discussion of radiological features pertaining to aggressive or non-aggressive properties, thereby allowing generation of a radiological differential
2012 Royal College of Pathologists of Australasia
Copyright © Royal College of pathologists of Australasia. Unauthorized reproduction of this article is prohibited. Copyright
Anatomical, Oral and Maxillofacial Pathology including workshops
RCPA QUALITY ASSURANCE PROGRAM: REVIEW OF THE UROLOGY MODULE Fiona Maclean Douglass Hanly Moir Pathology, Urology Module Convener RCPA QAP, Sydney, NSW, Australia In the course of the presentation a review of the urology module of the Royal College of Pathologists of Australasia Quality Assurance Program (RCPA QAP) will be made, including an assessment of the results pertaining to straightforward urogenital cases, and those that presented more of a challenge to respondents. One aspect that will be examined in more depth is the range of responses given in regard to Gleason scoring of prostate adenocarcinoma, an area that has not been formally assessed to date but will be assessed going forward. Discussion will also be made concerning the performance monitoring project and the framework to be introduced in regard to anatomical pathology. THYROPHOBIA: HOW TO OVERCOME YOUR FEAR OF THYROID FOLLICULAR TUMOURS Jennifer L. Hunt Department of Pathology and Laboratory Medicine, University of Arkansas for Medical Sciences, Little Rock, AR, USA Thyroid follicular derived lesions are common in surgical pathology and range from non-neoplastic and inconsequential all the way to rare aggressive tumours. Unfortunately, the histological features can overlap substantially across this spectrum of diagnostic possibilities. The field of thyroid pathology is also notorious for being difficult for the pathologist, with reportedly high interobserver variability, challenging interpretations of reported criteria, and a lack of good ancillary diagnostic assays. For all these reasons (and more), the pathologist facing a thyroid follicular lesion may have to wade through anxiety-provoking differential diagnoses that impact directly on patient care and follow-up. This course will provide extensive illustrations and images to describe some of the standard and more subtle histological and cytological features of thyroid follicular tumours. The presentation will provide the pathologist with hints and tips for practical use in their every-day sign-out, and will review some of the ancillary testing that has been reported in the literature. MOLECULAR PATHOLOGY FOR THE ANATOMICAL PATHOLOGIST: A CASE BASED DISCUSSION Jennifer L. Hunt Department of Pathology and Laboratory Medicine, University of Arkansas for Medical Sciences, Little Rock, AR, USA The field of anatomical pathology is quickly moving from a descriptive science, where diagnoses were made based upon the visual clues present on the haematoxylin and eosin (H&E) stained Print ISSN 0031-3025/Online ISSN 1465-3931
#
glass slide, to being a much more comprehensive diagnostic specialty. In the new era of surgical and cytopathology, interpretation of disease will take into account the morphology, the protein expression profile, the underlying genomic changes, and other alterations and changes that fundamentally affect the cells. This combined approach to diagnostics can potentially enable better diagnoses, more refined prognostics, and can impact on therapeutic modalities that are selected. While the field is exploding with new biomarkers and molecular targets, pathologists continue to struggle with difficult questions. What molecular markers should I be considering for different tumour types? How should the results be interpreted in the context of the morphological findings? What role does that pathologist have in guiding treatment based upon the molecular profiling of disease? These questions, and more, will be answered in this case-based presentation of some selected lesions in anatomical pathology that have newly developing molecular implications. HOW I HANDLE BONE SPECIMENS: A CASE BASED PRESENTATION Michael Dray Waikato Hospital, Hamilton, New Zealand This practical talk covers a range of bone specimens handled and reported at Middlemore Hospital, the site of the New Zealand Bone and Soft Tissue Tumour Registry. A variety of techniques and approaches for the gross handling of the specimens and equipment is discussed. This includes dealing with a large limb amputation specimen, to a limb salvage specimen comprising a wide excision of bone and soft tissues, to smaller excision specimens, curettings of bony tissue and finally undecalcified bone specimens for quantitative histomorphometry. The use of band saws, desk top skill saws, and hand saws is illustrated. Principles of decalcifying bone are also discussed. Cases that have been selected to demonstrate this range of techniques include synovial chondrosarcoma, pleomorphic undifferentiated sarcoma, conventional osteosarcoma, post-radiation osteosarcoma, degenerative joint disease, osteomyelitis, and hypophosphatasia concurrent with renal bone disease. AN APPROACH TO LUCENT LESIONS OF BONE: A CASE BASED PRESENTATION WITH RADIOLOGICAL AND HISTOPATHOLOGICAL CORRELATION Michael Dray1, Clinton Pinto2 1 Waikato Hospital, Hamilton, and 2Middlemore Hospital, South Auckland, New Zealand This practical talk covers a range of bony lesions that are often initially characterised on plain radiographs. A discussion of radiological features pertaining to aggressive or non-aggressive properties, thereby allowing generation of a radiological differential
2012 Royal College of Pathologists of Australasia
Copyright © Royal College of pathologists of Australasia. Unauthorized reproduction of this article is prohibited. Copyright