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effect relationship in hyperthermia treatment of rabbit bladder
of patients undergoing adrenalectomy who will benefit from this procedure.
1.
2.
Dao, T.L., and Nemoto, T. An Evaluation of Adrenalectomy and Andiogen in Disseminated Mammary Carcinoma. S.G. & 0. 121:1257-1262, December 1965. Breast Cancer - Early Fracchia, A.A., Randall, H.T., and Farrow, J.H., and Late. Chicago, Year Book Medical Publishers, Inc. 1970. pp 369-377.
(64) TIME/EFFECT
RELATIONSHIP
IN HYPERTHERMIA TREATMENT OF RABBIT BLADDER
Tapan A. Hazra, M.D., and Robert Howells, M.S. Virginia Commonwealth University, Medical College of Virginia, Department of Radiology, Divisions of Radiation Therapy & Oncology and Radiation Physics, Richmond, VA
If hyperthermia is to become clinically routine, it is important to establish a relationship between the time of heating and the long-term response of normal tiss,ue. One method of estimating such damage is to quantitatively study changes in the microvasculature. Using micro-angiographic techniques, such changes are studied for different heating times at 43'C and 45'C in the bladders of New Zealand White rabbits. A relationship between time and effect is established and different temperature level effects are compared. The heating is performed by hot water infusion and the temperatures are monitored by a thermistor. Micro-opaque material is introduced into the vasculature and 30 KVp radiographs are taken of the fixed bladders. Scoring is based on changes in the size and density of the vessels.
(65)
IMMUNOCOMPETENCE
OF PATIENTS WITH BRONCHOGENIC CARCINOMA
P. Huang, M.DT, S. Yang, Ph.D., S. Rafla, M.D., Ph.D. Imnunocompetence of patients suffering from bronchogenic carcinoma is recognized to be significantly depressed compared to normal controls. Fourty patients with bronchogenic carcinoma were investigated for immunocompetence before and six weeks after the end of a course of radiotherapy. Thirteen of the 40 cases had surgery within two months before irradiation, and the remaining were previously untreated.
In vitro tests used were mitogen stimulation (PHA), E-Rosette formation, T-cell level, in addition to lymphocyte enumeration and white blood counts. Findings were examined relative to clinical stage, age, 69
1.
2.
Dao, T.L., and Nemoto, T. An Evaluation of Adrenalectomy and Andiogen in Disseminated Mammary Carcinoma. S.G. & 0. 121:1257-1262, December 1965. Breast Cancer - Early Fracchia, A.A., Randall, H.T., and Farrow, J.H., and Late. Chicago, Year Book Medical Publishers, Inc. 1970. pp 369-377.
(64) TIME/EFFECT
RELATIONSHIP
IN HYPERTHERMIA TREATMENT OF RABBIT BLADDER
Tapan A. Hazra, M.D., and Robert Howells, M.S. Virginia Commonwealth University, Medical College of Virginia, Department of Radiology, Divisions of Radiation Therapy & Oncology and Radiation Physics, Richmond, VA
If hyperthermia is to become clinically routine, it is important to establish a relationship between the time of heating and the long-term response of normal tiss,ue. One method of estimating such damage is to quantitatively study changes in the microvasculature. Using micro-angiographic techniques, such changes are studied for different heating times at 43'C and 45'C in the bladders of New Zealand White rabbits. A relationship between time and effect is established and different temperature level effects are compared. The heating is performed by hot water infusion and the temperatures are monitored by a thermistor. Micro-opaque material is introduced into the vasculature and 30 KVp radiographs are taken of the fixed bladders. Scoring is based on changes in the size and density of the vessels.
(65)
IMMUNOCOMPETENCE
OF PATIENTS WITH BRONCHOGENIC CARCINOMA
P. Huang, M.DT, S. Yang, Ph.D., S. Rafla, M.D., Ph.D. Imnunocompetence of patients suffering from bronchogenic carcinoma is recognized to be significantly depressed compared to normal controls. Fourty patients with bronchogenic carcinoma were investigated for immunocompetence before and six weeks after the end of a course of radiotherapy. Thirteen of the 40 cases had surgery within two months before irradiation, and the remaining were previously untreated.
In vitro tests used were mitogen stimulation (PHA), E-Rosette formation, T-cell level, in addition to lymphocyte enumeration and white blood counts. Findings were examined relative to clinical stage, age, 69