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TISSUE MORPHOLOGY IN IN-STENT RE-RESTENOSIS LESIONS AFTER PACLITAXEL-ELUTING BALLOON DILATATION AND PLAIN OLD BALLOON ANGIOPLASTY FOR IN-STENT RESTENOSIS LESIONS: IMPACT OF PREVIOUS STENT
A1880 JACC April 1, 2014 Volume 63, Issue 12
TCT@ACC-i2: The Interventional Learning Pathway Tissue Morphology in In-stent Re-restenosis Lesions after Paclitaxel-eluting Balloon Dilatation and Plain Old Balloon Angioplasty for In-stent Restenosis Lesions: Impact of Previous Stent Poster Contributions Hall C Monday, March 31, 2014, 9:45 a.m.-10:30 a.m.
Session Title: Bioresorbable and Drug-Eluting Balloon Technologies Abstract Category: 41. TCT@ACC-i2: Coronary Intervention: Devices Presentation Number: 2109-279 Authors: Takeshi Tada, Kazushige Kadota, Seiji Habara, Hiroyuki Tanaka, Yasushi Fuku, Tsuyoshi Goto, Kazuaki Mitsudo, Kurashiki Central Hospital, Kurashiki, Japan Background: It was reported that tissue morphology of in-stent restenosis (ISR) lesions after drug-eluting stent (DES) implantation assessed with optical coherence tomography (OCT) was affected by stent type. Little was known about the re-restenotic tissue morphology after paclitaxel-coated balloon (PCB) dilatation and plain old balloon angioplasty (POBA). The aim of this study was to examine tissue morphology of in-stent re-restenosis lesions after PCB dilatation and POBA for DES-ISR lesions and to clarify the impact of previous stent type on it. Methods: Between January 2009 and March 2013, we performed OCT for in-stent re-restenosis lesions after PCB dilatation in 46 patients and those after POBA in 41 patients. Previous stents were 63 first generation DESs (sirolimus-eluting stent and paclitaxel-eluting stent) and 24 second generation DESs (zotarolimus-eluting stent, everolimus-eluting stent, and biolimus-eluting stent). The morphological assessment of neointimal tissue structure (homogeneous, heterogeneous, and layered type) was performed. Results: The results were shown in figure. There is a significant difference in tissue structure of in-stent re-restenosis lesions after PCB or POBA between 1st and 2nd generation DES (p=0.037). However, there was no difference in tissue structure between PCB dilatation and POBA in both 1st and 2nd generation DES. Conclusions: The tissue morphology of in-stent re-restenosis might be affected not by treatment modality but by previous stent type.
TCT@ACC-i2: The Interventional Learning Pathway Tissue Morphology in In-stent Re-restenosis Lesions after Paclitaxel-eluting Balloon Dilatation and Plain Old Balloon Angioplasty for In-stent Restenosis Lesions: Impact of Previous Stent Poster Contributions Hall C Monday, March 31, 2014, 9:45 a.m.-10:30 a.m.
Session Title: Bioresorbable and Drug-Eluting Balloon Technologies Abstract Category: 41. TCT@ACC-i2: Coronary Intervention: Devices Presentation Number: 2109-279 Authors: Takeshi Tada, Kazushige Kadota, Seiji Habara, Hiroyuki Tanaka, Yasushi Fuku, Tsuyoshi Goto, Kazuaki Mitsudo, Kurashiki Central Hospital, Kurashiki, Japan Background: It was reported that tissue morphology of in-stent restenosis (ISR) lesions after drug-eluting stent (DES) implantation assessed with optical coherence tomography (OCT) was affected by stent type. Little was known about the re-restenotic tissue morphology after paclitaxel-coated balloon (PCB) dilatation and plain old balloon angioplasty (POBA). The aim of this study was to examine tissue morphology of in-stent re-restenosis lesions after PCB dilatation and POBA for DES-ISR lesions and to clarify the impact of previous stent type on it. Methods: Between January 2009 and March 2013, we performed OCT for in-stent re-restenosis lesions after PCB dilatation in 46 patients and those after POBA in 41 patients. Previous stents were 63 first generation DESs (sirolimus-eluting stent and paclitaxel-eluting stent) and 24 second generation DESs (zotarolimus-eluting stent, everolimus-eluting stent, and biolimus-eluting stent). The morphological assessment of neointimal tissue structure (homogeneous, heterogeneous, and layered type) was performed. Results: The results were shown in figure. There is a significant difference in tissue structure of in-stent re-restenosis lesions after PCB or POBA between 1st and 2nd generation DES (p=0.037). However, there was no difference in tissue structure between PCB dilatation and POBA in both 1st and 2nd generation DES. Conclusions: The tissue morphology of in-stent re-restenosis might be affected not by treatment modality but by previous stent type.