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Treatment of gonorrheal vulvo vaginitis in children with follicular hormone
ABSTRACTS
1095
or 2-plus reaction. The author describes his technic of the complement fixation test for gonorrhea. He concludes that the production of complement fixing antibodies is dependent on the duration and spread of the infection. In acute complicated cases, the complement fixation test is strongly positive; in chronic cases the reaction is sometimes only weakly positive. This test is an aid in the determination of cure if previously positive reactions become negative, and the clinical and bacteriologic findings are also negative. A negative reaction by itself does not mean absence of gonococci. A positive reaction, persisting longer than one year after a clinical and bacteriologic cure, is an indication of a latent focus. This test is not intended to replace the older known methods of diagnosis but should be a supplementary procedure helpful in the diagnosis and in determination of a cure. W. B. SERBIN. Lewis, R. M., and Adler, E. L.: 33: 529, 1936.
Gonorrheal Vaginitis in Children, Am . .J. Surg.
The only treatment given consisted of intravaginal insNtion of a suppository rontaining 1,000 I.U. of amniotin each night at bedtime. The use of the suppositories was continued for at least two weeks after the vaginal discharge had ceased and the smears were negative. The external genitalia were washed when necessary. This therapy was continued until now 48 cases have completed their treatment and have been free from discharge and show negative smears :for period~ :from three we('ks to eleven months. On an average the smears in this series heeame eonsistently negative after 24.5 clays of treatment. It is significant that the hospital stay of ea~es treated in 1933 was 185 days and the cost to the city approximately $400.00 :for each ease. Moreover, during that year under the older methods of treatment only 82 were disrhargecl from a total of 185 cases. The saving of time to thr patirnt and expense to the ~ity would seem to be considerable. J. P. GREENHILL. Pongratz, R.: The Hormone Treatment of Gonorrheal Vulvovaginitis, Med. Klinik. 33: 93, 19il7. The author employed estrogenir hormones in the treatment of four children who had gonorrheal vulvovaginitis. In all four cases, negative smears were obtained after two weeks of treatment. In all, the vaginal disrharge disappeared rapidly. No disturbances were ob5erved such as swelling of the breastR or increased hair growth on the pubis. J. P. GREENHILL. Di Paola, G.: Treatment of Gonorrheal Vulvo Vaginitis in Children With Follicular Hormone, Bol. Soc. Obst. y ginec. de Buenos Aires 16: 242, 1937. The author reports the use of Progynon in the treatment of nine case~ of gonorrheal vulvovaginitis in children. Good results were obtained with eight of the patients over a period of two months. MARIO A. CASTALLO. Bierman, William: Treatment of Gonorrhea in Women by Means of Systemic and Additional Pelvic Heating, New England J. Med. 218: fifi, Hl38. Particularly good results in the treatment o:f gonorrheal infections are daimed for a combination of systemic raising of temperature with differentially increased pelvic heating. Body temperature is elevated by photothermal and shortwave heating with patient lying in bed or in hot water bath. After gt>neral body temperaturr ha~ reached 106° F. locally in the pelvis the temperature is raised to 108° or ll0° F. by special shortwave apparatus. Details of the technique are given. Of 125 patients, definitely infected with the gonococcus, in 93 per cent the gonococci disappeared. HUGO EHRENFEST.
1095
or 2-plus reaction. The author describes his technic of the complement fixation test for gonorrhea. He concludes that the production of complement fixing antibodies is dependent on the duration and spread of the infection. In acute complicated cases, the complement fixation test is strongly positive; in chronic cases the reaction is sometimes only weakly positive. This test is an aid in the determination of cure if previously positive reactions become negative, and the clinical and bacteriologic findings are also negative. A negative reaction by itself does not mean absence of gonococci. A positive reaction, persisting longer than one year after a clinical and bacteriologic cure, is an indication of a latent focus. This test is not intended to replace the older known methods of diagnosis but should be a supplementary procedure helpful in the diagnosis and in determination of a cure. W. B. SERBIN. Lewis, R. M., and Adler, E. L.: 33: 529, 1936.
Gonorrheal Vaginitis in Children, Am . .J. Surg.
The only treatment given consisted of intravaginal insNtion of a suppository rontaining 1,000 I.U. of amniotin each night at bedtime. The use of the suppositories was continued for at least two weeks after the vaginal discharge had ceased and the smears were negative. The external genitalia were washed when necessary. This therapy was continued until now 48 cases have completed their treatment and have been free from discharge and show negative smears :for period~ :from three we('ks to eleven months. On an average the smears in this series heeame eonsistently negative after 24.5 clays of treatment. It is significant that the hospital stay of ea~es treated in 1933 was 185 days and the cost to the city approximately $400.00 :for each ease. Moreover, during that year under the older methods of treatment only 82 were disrhargecl from a total of 185 cases. The saving of time to thr patirnt and expense to the ~ity would seem to be considerable. J. P. GREENHILL. Pongratz, R.: The Hormone Treatment of Gonorrheal Vulvovaginitis, Med. Klinik. 33: 93, 19il7. The author employed estrogenir hormones in the treatment of four children who had gonorrheal vulvovaginitis. In all four cases, negative smears were obtained after two weeks of treatment. In all, the vaginal disrharge disappeared rapidly. No disturbances were ob5erved such as swelling of the breastR or increased hair growth on the pubis. J. P. GREENHILL. Di Paola, G.: Treatment of Gonorrheal Vulvo Vaginitis in Children With Follicular Hormone, Bol. Soc. Obst. y ginec. de Buenos Aires 16: 242, 1937. The author reports the use of Progynon in the treatment of nine case~ of gonorrheal vulvovaginitis in children. Good results were obtained with eight of the patients over a period of two months. MARIO A. CASTALLO. Bierman, William: Treatment of Gonorrhea in Women by Means of Systemic and Additional Pelvic Heating, New England J. Med. 218: fifi, Hl38. Particularly good results in the treatment o:f gonorrheal infections are daimed for a combination of systemic raising of temperature with differentially increased pelvic heating. Body temperature is elevated by photothermal and shortwave heating with patient lying in bed or in hot water bath. After gt>neral body temperaturr ha~ reached 106° F. locally in the pelvis the temperature is raised to 108° or ll0° F. by special shortwave apparatus. Details of the technique are given. Of 125 patients, definitely infected with the gonococcus, in 93 per cent the gonococci disappeared. HUGO EHRENFEST.