- Email: [email protected]
Tri-professional Harmony
r
Book Pharm
.iii
~.~
Pharmacy Manpower Information Project, American Association of Colleges of Pharmacy, Christopher A. Rodowskas Jr. and W. Michael Dickson, Volumes 2and4,$12.50.
drug addiction as a social, legal and political problem as well as a medical one.
Drawn from the project's findings, AACP considered two areas of sufficiently .wide interest to publish and make available-volume 2 on "Pharmacy Manpower Forecasts and Projections" and volume 4 on "A Task Analysis of the Community Pharmacist."
Drug Dealers-Taking Action, Richard H. Blum and Associates, Jossey-Bass Publishers San Francisco, Calif., 1973, 312 pages, $10.75.
Drugs in Modern Society, Norman Imlah, MD, Vertex Books, Princeton, N.J., 1971, 151 pages,
The pharmaceutical industry is among the subjects included in this collection of articles on illicit drug distribution and use nationally and internationally. Subject areas considered include traffic, policing, detention and policy considerations.
The author, a psychiatrist, relates the healthy use of drugs to the unhealthy and examines drug control methods and treatment programs. He emphasizes
Methadone: Experiences and Issues, Carl D. Chambers and Leon Brill, Behavioral Publications, New York, 1973,411 pages, $19.95.
125. Abercrombie, G.F., and Davies, B.N., "The Action of Guanethidine With Particular Reference to the Sympathetic Nervous System," Brit. J. Pilarmacol. Chemother., 20, 171 (1963) 126. Bonra, A.L.A., and Green, A.F., "Adrenergic Neurone Blocking Agents," Ann. Rev. Pharmacol., 5, 183 (1965) 127. Furst, e.L, "The Biochemistry of Guanethidine," Advances Drug Res, 4, 133 (1967) 128. Rosenbloom, S.E., Shapera, R.P., Goldbloom, R.S., Sheps, M.e., and Shapiro, A.R., "Technique of Controlled Drug Assay, III. Comparison of Guanethidine Mecamylamine and Placebo in Hypertensive Patients," New Eng. J. Med., 268, 797 (1963) 129. Cohn, J.N., Liptak, T.E., and Freis, E.D., "Hemodynamic Effects of Guanethidine in Man," Circ. Res., 12,298 (1963) 130. Martin C., and Simpson, P., "The Absorption and Metabolism of Guanethidine in Hypertensive Patients Requiring Different Doses of the Drug," Clin Pharmacol. Ther., 12,73 (1971) 131. Rahn, K.H., and Goldberg, L.I., "Comparison of Antihypertensive Efficacy, Intestinal Absorption and Excretion of Guanethidine in Hypertensive Patients," Clin. Pharmacol. Ther., 10, 858 (1969) 132. McMartin, C., Rondel, R.K., Vinter,.l., Allan, B.R., Humberstone, P.M., Leishman, A.W.D., Sandler, G., and Thirkettle, 1.L., "The Fate of Guanethidine in Two Hypertensive Patients," Clin. Pharmacol. Tiler., 11,423 (1970) 133. Mitchell, J.R., Arias, L., and Oates, I.A.," Antagonism of the Antihypertensive Action of Guanethidine Sulfate by Desipramine Hydrochloride," JAMA, 202,973 (1967) 134. Meyer, J.F., McAllister, C.K., and Goldberg, L.L, "Insidious and Prolonged Antagonism of Guanethidine by Amitriptyline," JAMA, 213, 1487 (1970) 135. Hansen, P.D., Drug Interactions, Lea and Febiger, Philadelphia, Pa., 76, 186 (1971) 136. Ablad, B., "A Study of the Mechanism of the Hemodynamic Effects of Hydralazine in Man," Acta. Pharmacol., 20, Supp. I, 1 (1963) 137. Brunner, H., Hedwall, P.R., and Meier, M., "Influence of Adrenergic Beta-Receptor Blockade on the Acute Cardiovascular Effects of Hydralazine," Brit. J. Pharmacal. Chemother., 30, 123(1967) 138. Moyer, J.H., "Hydralazine (Apresoline) Hydrochloride: Pharmacological Observations and Clinical Results in the Therapy of Hypertension," Arch. Intern. Med., 91,419 (1953) 139. Stllnkard, A., Wertheimer, L., and Redisch, W., "Studies on Hydralazine: Evidence for a Peripheral Site of Action," J. Clin. Invest., 33, 1047 (1954) 140. Evans, D.A.P., and Whitc, T.A., "Human Acetylation Polymorphism," J. Lab. Clin. Med., 63, 394 (1964) 141. Weber, W.W., Cohen, S.N., and Steinberg, M.S., "Purification and Properties cf N-acetyltransferase From Mammalian Liver," Ann. N.Y. Acad. Sci., 151,734 (1968)
142. Evans, D.A.P., "Genetic Variations in the Acetylation of Isoniazide and Other Drugs," Ann. N.Y. Acad. Sci., 151,723 (1968) 143. Zacest, R., and Koch-Weser, J., "Relation of Hydralazine Plasma Concentration to Dosage and Hypotensive Action," Clin. Pharmacal. Therp., 13, 420 (1972) 144. Carver, B.N., Barrett, W., Cameron, A., and Yonkman, F.F., "The Activities of l-hydrazinophthalazine, a Hypotensive Agent'" JAPhA, 40, 559 (1951) 145. Perry, H.M., Jr., Schrocder, H.A., and Morrow, J.D., "Studies on the Control of Hypertension by Hyphex, LV. Levels of the Agents in Urine and Blood." Amer. J. Med. Sci .• 228, 405 (1954) 146. Orgain, E.S., Rowe, C.R., Jr., Sieber, H.A., and Grimson, K.S., "Caution With Regard to Use of Hexamethonium and Apresoline," JAMA, 149, 215(1952) 147. Moyer, J.H., "Hydralazine (Apresoline) Hydrochloride: Pharmacological Observations and Clinical Results in the Therapy of Hypertension," Arch. Intern. Med., 91, 419 (1953) 148. Marrow, J.D., Schroeder, H.A., and Perry, H.M., Jr. "Studies on the Control of Hypertension by Hyphcx. II. Toxic Reactions and Side Effects," Circulation, 9, 829 (1963) 149. Freis, E.n., "Hydralazine in Hypertension," Amer. Heart J., 67, 133 (1964) 150. Perry, H.M., Jr., Tan, E.M., and Carmody, S., "Relationship of Acetyl Transferase Activity to Antinuclear Antibodies and Toxic Symptoms in Hypertensive Patients Treated With Hydralazine," J. Lab. Clin. Med., 76, 114 (1970) 151. Lansbury, J., and Rogers, F.B., "The Hydralazine Syndromc," Bull. Kneum. Dis. 5, 85 (1955) 152. Prichard, B.N.C., "Hypotension From Beta Adrenergic Blocking Drugs," Amer. Hearl J., 69,716 (1965) 153. Prichard, B.N.C., and Gillam, P.M.S., "The Use of Propranolol in the Treatnlcnt of Hypertension," Brit. Med. J., 2, 725 (1964) 154. Waal, H.J., "Hypotensive Action of Propranolol," Clin. Pharmacol. Ther., 7, 588 (1966) 155. Prichard, B.N.C., and Gillam, P.M.S., "Propranolol in Hypertension," Amer. J. Cardiol., 18, 387 (1966). 156. Richards, F.A., "Propranolol in Hypertension," Amer. J. Cordial., 18, 384 (1966) 157. Paterson, J.W., and Dollery, C.T., "Effect of Propranolol in Mild Hypertension," Lancet, 2, 1148(1966) 158. Prichard, B.N.C., and GiHam, P.M.S., "Treatment of Hypertcnsion With Propranolol," Brit. Med. J., 1,7 (1969) 159. Prichard, B.N.C., "Propranolol as an Antihypertensive Agent," Amer. Heart J., 79, 128 (1970) 160. Frohlich, E.D., Tarazi, R.C., and Dustan, H.P., "The Paradox of Beta-Adrenergic Blockade in Hypertension," Circulation, 37,417 (1968) 161. Richardson, D.W., Freund, J., and Gear, A.S., "Effect of Propranolol on Elevated Arterial Blood Pressure," Circulation, 37, 534 (1968)
Original papers, a historical survey
FACULTY POSITION The College of Pharmacy at the Uni· versity of Houston is seeking a faculty member (assistant or associate pro· fessor) in pharmaceutical administra. tion. The position will require teach· ing, primarily at the undergraduate level, and research. Outstanding op· portunities are available to those with an interest in a patient/community orientation. Candidates are invited to send their curriculum vitae to: Ruth Kroeger, Ph.D. Chairman Clinical Pharmacy Department College of Pharmacy University of Houston Houston, Texas 77004
The University of Houston is an equal opportunity employer.
and a concluding summary in this book examine the wide variations in approach and experience found in America and abroad in using methadone in the treatment of heroin addiction. 162. Schroder, G., and Werro, L., "Hemodynamic Studies and Clinical Experience With Nethalide, Beta-Adrenergic Blocking Agent," Amer. J. Cardiol., 15, 58 (1965) 163. Lewis, P.I., Myers, M.G., Reid, J.L., and Pollery, G.T., "Mechanism of Beta.,Blockade Hypotension," New Eng. J. Med., 288, 689 (1973) 164. Buhler, F.R., Laragh, J.H., Baer, L., Vaughan, E.E., and Brunner, H.R., "Propranolol Inhibition of Renin Secretion," New Eng. J. Med., 287, 1210 (1972) 165. Thompson, F.D., Joekes, A.M., and Foulkes, D.M., "Pharmacodynamics of Propranolol in Renal Failure," Brit. Med. J., 2, 434 (1972) 166. "Build and Blood Pressure Study;" Society of Actuaries, Chicago, Ill. (1959) 167. Wilber, J.A., and Barrow, J.G., "Reducing Elevated Blood Pressure," Minn. Med. Part II, 52,1303 (1969) 168. Brunner, H.R., Laragh, I.H., Baer, L., Ncwton, M.A., Goodwin, F.T., Krakoff, L.R., Bard, R.H., and Buhler, F.R., "Essential Hypertension: Renin and Aldosterone, Heart Attack and Stroke," New Eng. J. Med., 286 441 (1972) 169. Mroczek, W.J., Finncrty, F.A., Jr., and Catt, K.J., "Low Renin Hypotension," New Eng. J. Med., 288, 1077 (1973) 170. Laragh, J.H., Baer, L., Brunner, H.R., Buhler, F.R., Sealey, J.E., and Vaughan, E.D., "Renin, Angiotensin and Aldosterone System in Pathogenesis and Management of Hypcrtensive Vascular Disease," Amer. J. Med., 52, 633 (1972) 171. Bourne, H.R., and Molmon, K.L., "Guides to thc Pharmacologic Management of Essential Hypertension," Rational Drug Therapy, 5, 1 (1971) 172. Koch-Wesec, J., "Correlation of Pathophysiology and Pharmacology in Primary Hypertension," Amer. J. Cardiol., 32, 499 (1973)
THE UNIVERSITY OF SYDNEY (Australia) CHAIR OF PHARMACEUTICS Applications are invited for the above chair in the De· partment of Pharmacy. Further information may be obtained by writing to the Registrar, University of Sydney, N.S.W., 2006, Australia.
Vol. NS14, No.4, April 1974
ZZl
Book Pharm
.iii
~.~
Pharmacy Manpower Information Project, American Association of Colleges of Pharmacy, Christopher A. Rodowskas Jr. and W. Michael Dickson, Volumes 2and4,$12.50.
drug addiction as a social, legal and political problem as well as a medical one.
Drawn from the project's findings, AACP considered two areas of sufficiently .wide interest to publish and make available-volume 2 on "Pharmacy Manpower Forecasts and Projections" and volume 4 on "A Task Analysis of the Community Pharmacist."
Drug Dealers-Taking Action, Richard H. Blum and Associates, Jossey-Bass Publishers San Francisco, Calif., 1973, 312 pages, $10.75.
Drugs in Modern Society, Norman Imlah, MD, Vertex Books, Princeton, N.J., 1971, 151 pages,
The pharmaceutical industry is among the subjects included in this collection of articles on illicit drug distribution and use nationally and internationally. Subject areas considered include traffic, policing, detention and policy considerations.
The author, a psychiatrist, relates the healthy use of drugs to the unhealthy and examines drug control methods and treatment programs. He emphasizes
Methadone: Experiences and Issues, Carl D. Chambers and Leon Brill, Behavioral Publications, New York, 1973,411 pages, $19.95.
125. Abercrombie, G.F., and Davies, B.N., "The Action of Guanethidine With Particular Reference to the Sympathetic Nervous System," Brit. J. Pilarmacol. Chemother., 20, 171 (1963) 126. Bonra, A.L.A., and Green, A.F., "Adrenergic Neurone Blocking Agents," Ann. Rev. Pharmacol., 5, 183 (1965) 127. Furst, e.L, "The Biochemistry of Guanethidine," Advances Drug Res, 4, 133 (1967) 128. Rosenbloom, S.E., Shapera, R.P., Goldbloom, R.S., Sheps, M.e., and Shapiro, A.R., "Technique of Controlled Drug Assay, III. Comparison of Guanethidine Mecamylamine and Placebo in Hypertensive Patients," New Eng. J. Med., 268, 797 (1963) 129. Cohn, J.N., Liptak, T.E., and Freis, E.D., "Hemodynamic Effects of Guanethidine in Man," Circ. Res., 12,298 (1963) 130. Martin C., and Simpson, P., "The Absorption and Metabolism of Guanethidine in Hypertensive Patients Requiring Different Doses of the Drug," Clin Pharmacol. Ther., 12,73 (1971) 131. Rahn, K.H., and Goldberg, L.I., "Comparison of Antihypertensive Efficacy, Intestinal Absorption and Excretion of Guanethidine in Hypertensive Patients," Clin. Pharmacol. Ther., 10, 858 (1969) 132. McMartin, C., Rondel, R.K., Vinter,.l., Allan, B.R., Humberstone, P.M., Leishman, A.W.D., Sandler, G., and Thirkettle, 1.L., "The Fate of Guanethidine in Two Hypertensive Patients," Clin. Pharmacol. Tiler., 11,423 (1970) 133. Mitchell, J.R., Arias, L., and Oates, I.A.," Antagonism of the Antihypertensive Action of Guanethidine Sulfate by Desipramine Hydrochloride," JAMA, 202,973 (1967) 134. Meyer, J.F., McAllister, C.K., and Goldberg, L.L, "Insidious and Prolonged Antagonism of Guanethidine by Amitriptyline," JAMA, 213, 1487 (1970) 135. Hansen, P.D., Drug Interactions, Lea and Febiger, Philadelphia, Pa., 76, 186 (1971) 136. Ablad, B., "A Study of the Mechanism of the Hemodynamic Effects of Hydralazine in Man," Acta. Pharmacol., 20, Supp. I, 1 (1963) 137. Brunner, H., Hedwall, P.R., and Meier, M., "Influence of Adrenergic Beta-Receptor Blockade on the Acute Cardiovascular Effects of Hydralazine," Brit. J. Pharmacal. Chemother., 30, 123(1967) 138. Moyer, J.H., "Hydralazine (Apresoline) Hydrochloride: Pharmacological Observations and Clinical Results in the Therapy of Hypertension," Arch. Intern. Med., 91,419 (1953) 139. Stllnkard, A., Wertheimer, L., and Redisch, W., "Studies on Hydralazine: Evidence for a Peripheral Site of Action," J. Clin. Invest., 33, 1047 (1954) 140. Evans, D.A.P., and Whitc, T.A., "Human Acetylation Polymorphism," J. Lab. Clin. Med., 63, 394 (1964) 141. Weber, W.W., Cohen, S.N., and Steinberg, M.S., "Purification and Properties cf N-acetyltransferase From Mammalian Liver," Ann. N.Y. Acad. Sci., 151,734 (1968)
142. Evans, D.A.P., "Genetic Variations in the Acetylation of Isoniazide and Other Drugs," Ann. N.Y. Acad. Sci., 151,723 (1968) 143. Zacest, R., and Koch-Weser, J., "Relation of Hydralazine Plasma Concentration to Dosage and Hypotensive Action," Clin. Pharmacal. Therp., 13, 420 (1972) 144. Carver, B.N., Barrett, W., Cameron, A., and Yonkman, F.F., "The Activities of l-hydrazinophthalazine, a Hypotensive Agent'" JAPhA, 40, 559 (1951) 145. Perry, H.M., Jr., Schrocder, H.A., and Morrow, J.D., "Studies on the Control of Hypertension by Hyphex, LV. Levels of the Agents in Urine and Blood." Amer. J. Med. Sci .• 228, 405 (1954) 146. Orgain, E.S., Rowe, C.R., Jr., Sieber, H.A., and Grimson, K.S., "Caution With Regard to Use of Hexamethonium and Apresoline," JAMA, 149, 215(1952) 147. Moyer, J.H., "Hydralazine (Apresoline) Hydrochloride: Pharmacological Observations and Clinical Results in the Therapy of Hypertension," Arch. Intern. Med., 91, 419 (1953) 148. Marrow, J.D., Schroeder, H.A., and Perry, H.M., Jr. "Studies on the Control of Hypertension by Hyphcx. II. Toxic Reactions and Side Effects," Circulation, 9, 829 (1963) 149. Freis, E.n., "Hydralazine in Hypertension," Amer. Heart J., 67, 133 (1964) 150. Perry, H.M., Jr., Tan, E.M., and Carmody, S., "Relationship of Acetyl Transferase Activity to Antinuclear Antibodies and Toxic Symptoms in Hypertensive Patients Treated With Hydralazine," J. Lab. Clin. Med., 76, 114 (1970) 151. Lansbury, J., and Rogers, F.B., "The Hydralazine Syndromc," Bull. Kneum. Dis. 5, 85 (1955) 152. Prichard, B.N.C., "Hypotension From Beta Adrenergic Blocking Drugs," Amer. Hearl J., 69,716 (1965) 153. Prichard, B.N.C., and Gillam, P.M.S., "The Use of Propranolol in the Treatnlcnt of Hypertension," Brit. Med. J., 2, 725 (1964) 154. Waal, H.J., "Hypotensive Action of Propranolol," Clin. Pharmacol. Ther., 7, 588 (1966) 155. Prichard, B.N.C., and Gillam, P.M.S., "Propranolol in Hypertension," Amer. J. Cardiol., 18, 387 (1966). 156. Richards, F.A., "Propranolol in Hypertension," Amer. J. Cordial., 18, 384 (1966) 157. Paterson, J.W., and Dollery, C.T., "Effect of Propranolol in Mild Hypertension," Lancet, 2, 1148(1966) 158. Prichard, B.N.C., and GiHam, P.M.S., "Treatment of Hypertcnsion With Propranolol," Brit. Med. J., 1,7 (1969) 159. Prichard, B.N.C., "Propranolol as an Antihypertensive Agent," Amer. Heart J., 79, 128 (1970) 160. Frohlich, E.D., Tarazi, R.C., and Dustan, H.P., "The Paradox of Beta-Adrenergic Blockade in Hypertension," Circulation, 37,417 (1968) 161. Richardson, D.W., Freund, J., and Gear, A.S., "Effect of Propranolol on Elevated Arterial Blood Pressure," Circulation, 37, 534 (1968)
Original papers, a historical survey
FACULTY POSITION The College of Pharmacy at the Uni· versity of Houston is seeking a faculty member (assistant or associate pro· fessor) in pharmaceutical administra. tion. The position will require teach· ing, primarily at the undergraduate level, and research. Outstanding op· portunities are available to those with an interest in a patient/community orientation. Candidates are invited to send their curriculum vitae to: Ruth Kroeger, Ph.D. Chairman Clinical Pharmacy Department College of Pharmacy University of Houston Houston, Texas 77004
The University of Houston is an equal opportunity employer.
and a concluding summary in this book examine the wide variations in approach and experience found in America and abroad in using methadone in the treatment of heroin addiction. 162. Schroder, G., and Werro, L., "Hemodynamic Studies and Clinical Experience With Nethalide, Beta-Adrenergic Blocking Agent," Amer. J. Cardiol., 15, 58 (1965) 163. Lewis, P.I., Myers, M.G., Reid, J.L., and Pollery, G.T., "Mechanism of Beta.,Blockade Hypotension," New Eng. J. Med., 288, 689 (1973) 164. Buhler, F.R., Laragh, J.H., Baer, L., Vaughan, E.E., and Brunner, H.R., "Propranolol Inhibition of Renin Secretion," New Eng. J. Med., 287, 1210 (1972) 165. Thompson, F.D., Joekes, A.M., and Foulkes, D.M., "Pharmacodynamics of Propranolol in Renal Failure," Brit. Med. J., 2, 434 (1972) 166. "Build and Blood Pressure Study;" Society of Actuaries, Chicago, Ill. (1959) 167. Wilber, J.A., and Barrow, J.G., "Reducing Elevated Blood Pressure," Minn. Med. Part II, 52,1303 (1969) 168. Brunner, H.R., Laragh, I.H., Baer, L., Ncwton, M.A., Goodwin, F.T., Krakoff, L.R., Bard, R.H., and Buhler, F.R., "Essential Hypertension: Renin and Aldosterone, Heart Attack and Stroke," New Eng. J. Med., 286 441 (1972) 169. Mroczek, W.J., Finncrty, F.A., Jr., and Catt, K.J., "Low Renin Hypotension," New Eng. J. Med., 288, 1077 (1973) 170. Laragh, J.H., Baer, L., Brunner, H.R., Buhler, F.R., Sealey, J.E., and Vaughan, E.D., "Renin, Angiotensin and Aldosterone System in Pathogenesis and Management of Hypcrtensive Vascular Disease," Amer. J. Med., 52, 633 (1972) 171. Bourne, H.R., and Molmon, K.L., "Guides to thc Pharmacologic Management of Essential Hypertension," Rational Drug Therapy, 5, 1 (1971) 172. Koch-Wesec, J., "Correlation of Pathophysiology and Pharmacology in Primary Hypertension," Amer. J. Cardiol., 32, 499 (1973)
THE UNIVERSITY OF SYDNEY (Australia) CHAIR OF PHARMACEUTICS Applications are invited for the above chair in the De· partment of Pharmacy. Further information may be obtained by writing to the Registrar, University of Sydney, N.S.W., 2006, Australia.
Vol. NS14, No.4, April 1974
ZZl