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Trials and Tribulations of a Pioneer Anatomist
ULTRASONIC NEBULIZATION IN CHRONIC OBSTRUCTIVE LUNG DISEASE
ings of posttreatment improvement of breathing and easier expectoration of sputa. This was equally true of those who had ultrasonic delivered by IPPB, in whom the incidence of discomfort was even higher. How much of the improvement was real and how much the inHuence of exposure to impressive and uncomfortable treatment is difficult to assess objectively.
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1 Andrews AH: Ultrasonic aerosol generator: A new dimension in aerosol therapy; preliminary report. Presbyt-St Luke Hosp Med Bull 3: 155, 1964 2 Andrews AH: Application of the ultrasonic nebulizer in the treabnent of bronchostasis, in Proceedings of the First Conference on Clinical Applications of the Ultrasonic Nebulizer 1966, pp 59-61
3 Stevens HR, Albregt HB: Assessment of ultrasonic nebulization. Anesthesiology 27: 648, 1966 4 Williams TJ, Localization of material aerosolized by ultrasonic nebulizer as determined by a colorimetric method,
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in Proceedings of the First Conference on Clinical Applications of the Ultrasonic Nebulizer 1966, pp 25-27 Sputum inducement-aerosol vs bronchial lavage, in Proceedings of the First Conference on Clinical Applications of the Ultrasonic Nebulizer 1966, pp 49-50 Abernethy JD: Effects of inhalation of an artificial fog. Thorax, 3:421, 1968 Cheney FW Jr, Butler J: Effects of ultrasonically-produced aerosols on airway resistance in man. Anesthesiology, 29:1099,1968 Pflug AE, Cheney FW Jr, Butler J: The effects of an ultrasonic aerosol on pulmonary mechanics and arterial blood gases in patients with chronic bronchitis. Amer Rev Resp Dis 101 :710, 1970 Noehren T: Editorial-Is positive pressure breathing overrated? Chest 57:507,1970 Wolfsdorf J, Swift DL, Avery ME: Mist therapy reconsidered; an evaluation of respiratory deposition of labelled water aerosols produced by jet and ultrasonic nebulizers. Pediatrics 43:799, 1969 Sheldon GP: Pressure breathing in chronic obstructive lung disease. Medicine 42: 197, 1963
Reprint requests: Dr. Taguchi, VA Center, 4100 West Third Street, Dayton 45428
Trials and Tribulations of a Pioneer Anatomist Andreas Vesalius ( 1514-1564) , a man of German extraction, a teacher at Padua, was the first true anatomist. He recorded what he saw not what authority said he should see. The fruit of his work is the great DE FABRICA HUMANI CORPORIS, published in 1543. The response was immediate and violent. By some he was tolerantly ignored, others openly derided him, some used the authorities to impose upon him petty persecutions. In indignation Vesalius, then barely thirty, burned his manuscripts, retired from anatomy, and became physi-
CHEST, VOL. 60, NO.4, OCTOBER 1971
cian to Emperor Charles V. Vesalius in retirement was being forgotten. In 1563, he went on a pilgrimage to Jerusalem. On his way back, he received word that he was to have back his old position at Padua. But he was never to realize the ambition that had cankered him so since the day he had become a courtier. On the journey home he sickened and died. Haggard H W: Mystery, Magic and Medicine. Garden City, N Y, Doubleday, Doran, 1933
ings of posttreatment improvement of breathing and easier expectoration of sputa. This was equally true of those who had ultrasonic delivered by IPPB, in whom the incidence of discomfort was even higher. How much of the improvement was real and how much the inHuence of exposure to impressive and uncomfortable treatment is difficult to assess objectively.
5 6
7 8
1 Andrews AH: Ultrasonic aerosol generator: A new dimension in aerosol therapy; preliminary report. Presbyt-St Luke Hosp Med Bull 3: 155, 1964 2 Andrews AH: Application of the ultrasonic nebulizer in the treabnent of bronchostasis, in Proceedings of the First Conference on Clinical Applications of the Ultrasonic Nebulizer 1966, pp 59-61
3 Stevens HR, Albregt HB: Assessment of ultrasonic nebulization. Anesthesiology 27: 648, 1966 4 Williams TJ, Localization of material aerosolized by ultrasonic nebulizer as determined by a colorimetric method,
9 10
11
361
in Proceedings of the First Conference on Clinical Applications of the Ultrasonic Nebulizer 1966, pp 25-27 Sputum inducement-aerosol vs bronchial lavage, in Proceedings of the First Conference on Clinical Applications of the Ultrasonic Nebulizer 1966, pp 49-50 Abernethy JD: Effects of inhalation of an artificial fog. Thorax, 3:421, 1968 Cheney FW Jr, Butler J: Effects of ultrasonically-produced aerosols on airway resistance in man. Anesthesiology, 29:1099,1968 Pflug AE, Cheney FW Jr, Butler J: The effects of an ultrasonic aerosol on pulmonary mechanics and arterial blood gases in patients with chronic bronchitis. Amer Rev Resp Dis 101 :710, 1970 Noehren T: Editorial-Is positive pressure breathing overrated? Chest 57:507,1970 Wolfsdorf J, Swift DL, Avery ME: Mist therapy reconsidered; an evaluation of respiratory deposition of labelled water aerosols produced by jet and ultrasonic nebulizers. Pediatrics 43:799, 1969 Sheldon GP: Pressure breathing in chronic obstructive lung disease. Medicine 42: 197, 1963
Reprint requests: Dr. Taguchi, VA Center, 4100 West Third Street, Dayton 45428
Trials and Tribulations of a Pioneer Anatomist Andreas Vesalius ( 1514-1564) , a man of German extraction, a teacher at Padua, was the first true anatomist. He recorded what he saw not what authority said he should see. The fruit of his work is the great DE FABRICA HUMANI CORPORIS, published in 1543. The response was immediate and violent. By some he was tolerantly ignored, others openly derided him, some used the authorities to impose upon him petty persecutions. In indignation Vesalius, then barely thirty, burned his manuscripts, retired from anatomy, and became physi-
CHEST, VOL. 60, NO.4, OCTOBER 1971
cian to Emperor Charles V. Vesalius in retirement was being forgotten. In 1563, he went on a pilgrimage to Jerusalem. On his way back, he received word that he was to have back his old position at Padua. But he was never to realize the ambition that had cankered him so since the day he had become a courtier. On the journey home he sickened and died. Haggard H W: Mystery, Magic and Medicine. Garden City, N Y, Doubleday, Doran, 1933