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regarding the amount of resected tissue, operating time, preoperative-postoperative Hb levels and hemostatic variables. In the both groups, no patient required blood transfusion on postoperatively. Conclusions: NSAIDs is not a contraindication to TUR-P and should be used in the control of postoperative pain if it is indicated in the patient. UP-3.076 Sexuality and Management of Benign Prostatic Hyperplasia with Alfuzosin 10mg OD Telich M1, Gomez P2, Barbales H3, Lopez P4 1 Angeles Del Pedregal Hospital, Mexico City, Mexico; 2Universidad de Colombia, Bogota, Colombia; 3Clı´nicas Centro Medico II, Guatemala, Guatemala; 4Hospital Militar, Quito, Ecuador Introduction and Objective: to assess improvement in MSHQ (Male Sexual Health Questionnaire) ejaculation domain from baseline to end of treatment (week 24 with alfuzosin 10 mg OD) in Latin American males with moderate to severe lower urinary tract symptoms (LUTS). Materials and Methods: There were 423 sexually active men with an I-PSS total score ⬎7, suggestive of benign prostatic hyperplasia (BPH) (mean age 61 yrs, mean prostate volume 40.2 ml, mean IPSS 17.4), who were enrolled in a 6-month open, non-comparative, multicenter study with alfuzosin 10mg OD in Latin America (Colombia, n⫽105, Ecuador, n⫽49, Guatemala, n⫽46, Mexico, n⫽223). I-PSS was filled in at baseline, 1, 4, 12 and 24 weeks. The MSHQ ejaculation domain, which evaluates 7 components of ejaculation and bother associated with EjD, was filled in at baseline, 4, 12 and 24 weeks. Most patients (95.3%) were Hispanic, 23.17% hypertensive and mean age at onset of LUTS was 58 years. Results: Mean (SD) ejaculation score significantly improved from 26.2 (⫾5.37) at baseline to 28.8 (⫾5.79) at end-point (mean (SD) change 2.60 (⫾6.26), median 2.0, with 95% CI between 1.95 and 3.17, p⬍0.001). 27.9% of patients showed a 20% or greater improvement in the ejaculation score. I-PSS score significantly improved from 17.24 (SD⫾5.47) at baseline to 7.14 (SD⫾5.42) at end-point (mean change 10.09 (⫾6.43), p⬍0.001). Overall, 368 patients (87.6%) had an improvement of IPSS of at least 3 points. Symptoms’ relief was perceived by most patients (69.3%) from the first week of treatment, 8.9% from the second week and 7.2% from 3-4 weeks. 14.6% perceived no im-
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provement. Overall, 65 patients (15.1%) experienced adverse events, most mild in severity (most common were dizziness 2%, headache 0.9%, diarrhea 1%); only 3 of them reported serious events: 2 developed acute urinary retention and 1 required BPH surgery. In total, 18 patients (4%) dropped out due to adverse events and none were considered related to the study medication. Conclusions: Alfuzosin 10mg OD administered for 6 months in Latin America males is effective, well tolerated and shows no deleterious effect on sexual function. It may even improve erectile and ejaculatory dysfunction and satisfaction with sex life. UP-3.077 The Improvement of the Operative Technique in TUEB Chen X1, Chen Q2, Wang Z2 1 Department of Urology, Jingan District Central Hospital, Shanghai, China; 2Department of Urology, the 9th People’s hospital, Shanhai Jiaotong Universty, Shanghai,China Introduction and Objective: To introduce our improvement of the operative technique in TUEB in the past 7 years. Materials and Methods: From February in 2002 to December in 2008, 477 cases of TUEB were performed in our group. According to the differences of the operative method, 30 cases of TUEB, which by the older operative method, was put in Group 1, and other 30 cases of TUEB, which by the improved operative method, in Group 2. The average age of the patients in Group 1 was 75.9⫾7.6 years; the average volume of the prostate in Group 1 was 91.2⫾37.1 ml. The average age of the patients in Group 2 was 71.2⫾5.6 years; the average volume of the prostate in Group 2 was 90.5⫾38.1 ml. Gyrus Plasma-Kinatic System and endoscope system was used. Normal Saline solution acts as the working medium and irrigating fluids. Using “back-hand stroke” technique and enucleating act, the prostatic adenoma was dissected and enucleated in the surgical capsule, then resected. In this procedure, the limits between the hyperplastic adenoma and the surgical capsule was affirmed and the blood supply was blocked. The transversal muscle fibre was not cut off, so the integrality of bladder neck was kept up. Comparing with Group 1, some different operative technique was applied in Group 2 in treating starting, anchoring spot and middle lobe. Results: All of the patients in the two groups underwent their operation suc-
cessfully, passed their water comfortably and were out of hospital. In Group 1 the average time of the operation was 97.4⫾32.4 mins, the average weight resected tissue was 59.8⫾27.9 gram, the average bleeding volume was 263.7⫾198.6 ml. In Group 2 the average time of the operation was 85.6⫾31.2 mins, the average weight resected tissue was 62.0⫾22 gram, the average bleeding volume was 211.5⫾87.4 ml. Conclusions: The improvement of the operative technique should have TUEB shortened operative time, lessened bleeding and got more reasonable and safer process. UP-3.078 Greenlight HPS 120-W Laser for Benign Prostatic Hyperplasia (Report of 34 Cases) Shan Y, Xue B, Zang Y, Yang D, Sun C Department of Urology, The Second Affiliated Hospital of Soochow University, Suzhou, China Introduction and Objective: Photoselective vaporization of the prostate (PVP) using the Greenlight HPS 120-W laser is a recent technique for the treatment of lower urinary tract symptoms (LUTS) secondary to benign prostatic hyperplasia (BPH). We report the effectiveness and safety of Greenlight HPS 120-W laser in men with symptomatic BPH and summary our initial experience. Materials and Methods: From September 2007 to May 2008, 34 patients with BPH were underwent 120-W Photoselective vaporization of the prostate. The mean patient age was 76.3 years 䊐6889䊐and mean prostate volume 68.6 ml (32-128), mean maximum urinary flow rate (Qmax) 6.9 ml/s (3.6-14), and mean sonographically measured postvoid residual volume 88ml (76-320), mean International Prostate Symptom Score (IPSS) 25.8 (19-29). Results: Mean operative time was 58.2 minutes (range 45 to 120 minutes). Foley catheters were removed with 24 hours in 9 patients, and these patients could urinate well. The other 25 patients could urinate well after Foley catheters were removed within 3-5 days. At 6- month follow up, the mean IPSS decreased from 25.8⫾3.8 to 12.3⫾1.8 (P⬍0.01), the mean PVR decreased from 88.3⫾32.7 ml to 10.1⫾15.6 ml (P⬍0.01), while the Qmax increased from 6.81⫾2.55 ml/s to 16.57⫾4.15 ml/s (P⬍0.01). Complications consisted of 2 hematuria, 2 urinary infection, and 1 mild-moderate dysuria. Conclusions: 120-W PVP provides a safe,
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effective and simple procedure for the treatment of BPH. Patients suffer pain little, and recover quickly from illness. It also does well in patients with large prostates.
UP-3.079 An Efficient Way of Trial without Catheter Following an Episode of Acute Urinary Retention Ong E1, Gregor N1, Hanley J1, Graham C2, McNeill A1, Riddick A1 1 Western General Hospital, Edinburgh, United Kingdom; 2Wellcome Trust Clinical Research Facility, Edinburgh, United Kingdom Introduction and Objective: This randomized controlled trial evaluates two methods of trial without catheter (TWOC) in men following an episode of acute urinary retention: (1) standard catheter removal and (2) bladder infusion prior to TWOC. Materials and Methods: Thirty-nine consecutive patients were randomized into two groups. Standard group underwent the standard catheter removal (n⫽20). Infused group underwent saline bladder infusion over 5 minutes prior to TWOC (n⫽19). Outcome measures included time to discharge, outcome of TWOC, patient discomfort and voiding efficiency. Results: There was no difference in successful TWOC in both groups. For discharge time, there was a significant difference with the infused group being discharged at a mean of 82.2 minutes earlier. Bladder infusion was less well tolerated with 26% of infused patients experiencing some discomfort compared to none in the standard group. There was no difference in voiding efficiency in both groups. Voiding efficiency at first void was significantly higher when passing a TWOC compared to when failing to void (p⫽0.001). Conclusion: Bladder infusion prior to TWOC provides the same outcome as standard catheter removal but provides an earlier discharge. Voiding efficiency at first void provides an earlier and reliable prediction of success in TWOC.
UP-3.080 Holmium Laser Prostatectomy (HoLEP): Early report Selmy G, Mahmoud M, El-Batanouny A, El-Kholy M, Hathot E, Setohy I Al-Azhar University, Cairo, Egypt Introduction and Objective: Holmium laser enucleation of the prostate (HoLEP)
is a well established procedure for the treatment of benign prostatic hyperplasia. Here we report our experience of the efficacy, and safety of HoLEP. Materials and Methods: We collected data from 60 consecutive patients who had undergone HoLEP for benign prostatic hyperplasia. All the patients were done in Shrook hospital. Patient baseline characteristics, perioperative data, and postoperative outcome were collected. Hospital stay, operating time, blood loss, catheterization time, as well as the international prostate symptom score (IPSS), maximum urinary flow rate (Q max) and postvoid residual volume (RU) before and 3 months after the surgery. All complications were noted. Patients were contacted by telephone. Results: The mean age was 67 years (range 45 to 91) and procedure time was about 85.3 minutes (range 39 to 165) enucleation time was about 66.1 minutes (range 30-120) and morcellation time was about 19.2 minutes (range 9-45). The mean adenoma weight was 56.7g (range 11g to 90g). The mean hospital stay was 1 day, with 98.8% of patients discharged after an overnight stay without a catheter. None of patients required postoperative transfusions. No deaths, major complications (myocardial infarction or pulmonary embolism), bladder mucosal morcellation injuries had occurred. Intra-operative complications consisted of three capsular perforations (5%), one incomplete morcellation (1.6%). HoLEP resulted in a significant improvement in voiding symptoms and maximum urinary flow rate (Q max) (average from 9.1 to 19.4). There are improvements in post-void residual urine, International Prostate Symptom Score (23.5 to 9.02). Regarding continence, 10 % complaint from urge incontinent, 2 % from total incontinence and the rest is continent before operation. 13.3 % complaint of urge incontinence in the first 3 months, and the rest were continent. And follow up after 6 months the average Qmax was 20.8 and insignificant residual urine, and the average IPSS was 8.7. no one complaint of urge incontinence by the end of the 6 months. Conclusion: Holmium laser enucleation of the prostate is a safe and effective treatment option for benign prostatic hyperplasia and can be performed with minimal complication risks, blood loss. Patients can expect an overnight hospital stay and discharge without an indwelling catheter. But it is so expensive and needs experience. Some urge incontinence occurs during the first months, which is self-limited.
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UP-3.081 The Analysis of Causes and Clinic Strategy for Hemorrhage after TURP Chen Z, Liu X Renmin Hospital of Wuhan University, Wuhan, China Introduction and Objective: Transurethral resection prostate (TURP) is the gold standard of the transurethral resection prostate. The TURP is small, the time is short and the postoperative recovery is quick. Postoperative hemorrhage is one of the TURP common complications. The article is to analysis of causes and clinic strategy of the hemorrhage after TURP. Materials and Methods: The 52 cases who take the operation of TURP in our hospital from May of 2007 to the July of 2008 were chosen. Each group has 52 cases, aged from 55 to 86 (the average 73). Before the operation we tested the IPSS, TPSA, FPSA, the digital examination of rectum, the flow rate, and measured volume residual urine and calculated the weight of prostate. Results: There are 10 cases bleed after operation prophase (in the 48 hours).The blood volume was about 800⬃1200ml. The earliest secondary hemorrhage was happened in the 30min after operation. There were 8 cases of tardive bleeding (after 48 hours after operation). There were many methods to handle the postoperative hemorrhage, such as expectant treatment, hemostasis in the resectoscope or open operation. In the 18 cases, 9 take the expectant treatment, 7 in the resectoscope and 2 take the open operation. Conclusion: Completed preoperative analysis, the right intraoperative, postoperative treatment and continuous improving operation skills prevented and decreased the occurrence of postoperative treatment after TURP. UP-3.082 The Learning Curve of 120-W Photoselective Vaporization of the Prostate for Benign Prostatic Hyperplasia Zang Y, Shan Y, Xue B, Yang D, Sun C, Gao J Department of Urology, The Second Affiliated Hospital of Soochow University, Suzhou, China Introduction and Objective: To evaluate the learning curve of 120-W photoselective vaporization of the prostate (PVP) as treatment for Benign Prostatic Hyperplasia (BPH). Materials and Methods: A total of 30 consecutive patients treated with 120-W PVP were included in this evaluation to study the learning curve of an endourologist with experience at performing 80-W PVP in more than 400 cases. To assess the
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