- Email: [email protected]
USA — Enzyme-modified electrodes for peroxide, choline, and acetylcholine
Biosensors & Bioelectronics Vol. 10 No. 9/10 (1995)
immunosorbent assay. A major advantage of the fiber optic biosensor is that results can be generated within minutes while isolating the user from hazardous samples. These factors favour development of this biosensor into a facile and rapid diagnostic device.
Contact: Naval Research Laboratory, CBMSE, Washington, DC 20375-5348, USA. USA Enzyme-modified electrodes for peroxide, choline, and acetylcholine In TRENDS ANAL. CHEM. (14/4 (164-169) 1995) M.G. Gagruilo and A.C. Michael of the University of Pittsburgh report on "Enzyme-modified electrodes for peroxide, choline, and acetylcholine,. Enzyme-modified electrodes for peroxide, choline, and acetylcholine have been developed. Horseradish peroxidase, choline oxidase, and acetylcholinesterase were immobilized within a cross-linkable, redox polymer deposited onto the surface of carbon electrodes. The amperometric, enzyme-based sensors were developed for use in the extracellular fluid of brain tissue and for single-cell analysis. The sensitivity, selectivity, size, and response time of the sensors were addressed.
Contact: Department of Chemistry, Chevron Science Center, University of Pittsburgh, Pittsburgh, PA 15260, USA. Spain - Thick-film technology In TRENDS ANAL. CHEM. (14/5 (225-231) 1995) C.A. Galan-Vidal, J. Munoz, C. Dominguez and S. Alegret of the Universidad Autonoma de Barcelona report on "Chemical sensors, biosensors and thick-film technology". Trends in thick-film technology as applied in chemical sensor and biosensor fabrication are briefly reviewed and discussed. Current work aims at the production of sensor devices with a wide application range and commercial viability. Planar technologies are being employed for developing solid-state sensors having low cost, small size and high reproducibility. These technologies are compatible with silicon-based procedures that
vi
permit integration of the sensor and the associated electronic circuitry in the same chip. The use of planar technologies to produce sensors based on thick films can be very convenient since it calls for an inexpensive infrastructure, and is feasible for small to medium production runs. Once developed, a thick film fabrication process can easily be combined with other planar technologies (chemical vapour deposition, plasma etching, etc.). The resulting devices can be produced in high volume at lower cost, with greater reproducibility and with further miniaturization.
Contact: Grupo de Sensores/Biosensores, Departamento de Quimica, Universidad Autonoma de Barcelona, 08193 Bellaterra, Barcelona, Spain. Bulgaria - Generalized model for biosensors In ANAL. CHIM. ACTA (307/1 (27-36)1995) A. Neikov and S. Sokolov of the Technical University, Sofia report on "Generalized model for enzyme amperometric biosensors". A general model for a range of enzyme amperometric biosensors is proposed. The elements of the model reflect the separate groups ofphysicaUy identical parameters determining the biosensor behaviour, as each element gives the number of the parameters in the corresponding group. Altering the values of these elements generates a range of particular biosensor models. In order to test their applicability four models of different complexity were developed and compared. In addition an interesting effect concerning the mutual action of two enzymes is predicted.
Contact: Department of Bioengineering, Technical University, Sofia 1156, Bulgaria. Portugal - A nitrite reductase biosensor? In BIOCHEM. BIOPHYS. RES. COMMUN. (209/3 (1018-1025)1995) M. Scharf, C. Moreno, C. Costa, C. Van Dick, W.J. Payne, J. LeGall, I. Moura and J.G. Moura of Faculdade Ciencias Tecnol, Univ Nova report on "Electrochemical, studies on nitrite reductase towards a biosensor". A c-type hexaheme nitrite reductase (NiR)
immunosorbent assay. A major advantage of the fiber optic biosensor is that results can be generated within minutes while isolating the user from hazardous samples. These factors favour development of this biosensor into a facile and rapid diagnostic device.
Contact: Naval Research Laboratory, CBMSE, Washington, DC 20375-5348, USA. USA Enzyme-modified electrodes for peroxide, choline, and acetylcholine In TRENDS ANAL. CHEM. (14/4 (164-169) 1995) M.G. Gagruilo and A.C. Michael of the University of Pittsburgh report on "Enzyme-modified electrodes for peroxide, choline, and acetylcholine,. Enzyme-modified electrodes for peroxide, choline, and acetylcholine have been developed. Horseradish peroxidase, choline oxidase, and acetylcholinesterase were immobilized within a cross-linkable, redox polymer deposited onto the surface of carbon electrodes. The amperometric, enzyme-based sensors were developed for use in the extracellular fluid of brain tissue and for single-cell analysis. The sensitivity, selectivity, size, and response time of the sensors were addressed.
Contact: Department of Chemistry, Chevron Science Center, University of Pittsburgh, Pittsburgh, PA 15260, USA. Spain - Thick-film technology In TRENDS ANAL. CHEM. (14/5 (225-231) 1995) C.A. Galan-Vidal, J. Munoz, C. Dominguez and S. Alegret of the Universidad Autonoma de Barcelona report on "Chemical sensors, biosensors and thick-film technology". Trends in thick-film technology as applied in chemical sensor and biosensor fabrication are briefly reviewed and discussed. Current work aims at the production of sensor devices with a wide application range and commercial viability. Planar technologies are being employed for developing solid-state sensors having low cost, small size and high reproducibility. These technologies are compatible with silicon-based procedures that
vi
permit integration of the sensor and the associated electronic circuitry in the same chip. The use of planar technologies to produce sensors based on thick films can be very convenient since it calls for an inexpensive infrastructure, and is feasible for small to medium production runs. Once developed, a thick film fabrication process can easily be combined with other planar technologies (chemical vapour deposition, plasma etching, etc.). The resulting devices can be produced in high volume at lower cost, with greater reproducibility and with further miniaturization.
Contact: Grupo de Sensores/Biosensores, Departamento de Quimica, Universidad Autonoma de Barcelona, 08193 Bellaterra, Barcelona, Spain. Bulgaria - Generalized model for biosensors In ANAL. CHIM. ACTA (307/1 (27-36)1995) A. Neikov and S. Sokolov of the Technical University, Sofia report on "Generalized model for enzyme amperometric biosensors". A general model for a range of enzyme amperometric biosensors is proposed. The elements of the model reflect the separate groups ofphysicaUy identical parameters determining the biosensor behaviour, as each element gives the number of the parameters in the corresponding group. Altering the values of these elements generates a range of particular biosensor models. In order to test their applicability four models of different complexity were developed and compared. In addition an interesting effect concerning the mutual action of two enzymes is predicted.
Contact: Department of Bioengineering, Technical University, Sofia 1156, Bulgaria. Portugal - A nitrite reductase biosensor? In BIOCHEM. BIOPHYS. RES. COMMUN. (209/3 (1018-1025)1995) M. Scharf, C. Moreno, C. Costa, C. Van Dick, W.J. Payne, J. LeGall, I. Moura and J.G. Moura of Faculdade Ciencias Tecnol, Univ Nova report on "Electrochemical, studies on nitrite reductase towards a biosensor". A c-type hexaheme nitrite reductase (NiR)