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Use of cyanoacrylate tissue adhesive to orientate histopathological specimens
YBJOM-5207;
ARTICLE IN PRESS
No. of Pages 1
Available online at www.sciencedirect.com
ScienceDirect British Journal of Oral and Maxillofacial Surgery xxx (2017) xxx–xxx
Letter to the Editor
Use of cyanoacrylate tissue adhesive to orientate histopathological specimens
Conflict of interest We have no conflicts of interest.
Sir, The correct orientation of specimens is important for histopathological diagnosis. Occasionally, after a resected specimen has been inspected, it may be necessary to remove a further section because of concern about involved margins. It is important to orient the second sample correctly with the first, or the potential for error is increased. The use of sutures to bind the specimens can cause artefacts, which can compromise histopathological evaluation. We describe a method to help orientate these specimens accurately. After resection, and before the tissues are placed in formalin, the specimens are arranged by the surgeon into the correct position. Cyanoacrylate tissue glue is then applied to the two sections, which are opposed in their correct orientation, and the glue is allowed to dry (Fig. 1). The sample can then be placed in formalin. Cyanoacrylate does not alter the integrity of the tissue and leaves minimal artefacts on histological examination.1
Ethics statement/confirmation of patient’s permission Not required. Reference 1. Zeikus P, Dufresne R. Novel technique for use of cyanoacrylate in Mohs surgery. Dermatol Surg 2006;32:943–4.
W. Rodgers ∗ K. Mitsimponas K. Shakib Department of Oral & Maxillofacial Surgery, Royal Free Hospital NHS Trust, London, UK ∗ Corresponding author. E-mail address: [email protected] (W. Rodgers)
Fig. 1. Specimens oriented and joined together with cyanoacrylate tissue glue as indicated by the arrows. http://dx.doi.org/10.1016/j.bjoms.2017.05.020 0266-4356/© 2017 The British Association of Oral and Maxillofacial Surgeons. Published by Elsevier Ltd. All rights reserved.
Please cite this article in press as: Rodgers W, et al. Use of cyanoacrylate tissue adhesive to orientate histopathological specimens. Br J Oral Maxillofac Surg (2017), http://dx.doi.org/10.1016/j.bjoms.2017.05.020
ARTICLE IN PRESS
No. of Pages 1
Available online at www.sciencedirect.com
ScienceDirect British Journal of Oral and Maxillofacial Surgery xxx (2017) xxx–xxx
Letter to the Editor
Use of cyanoacrylate tissue adhesive to orientate histopathological specimens
Conflict of interest We have no conflicts of interest.
Sir, The correct orientation of specimens is important for histopathological diagnosis. Occasionally, after a resected specimen has been inspected, it may be necessary to remove a further section because of concern about involved margins. It is important to orient the second sample correctly with the first, or the potential for error is increased. The use of sutures to bind the specimens can cause artefacts, which can compromise histopathological evaluation. We describe a method to help orientate these specimens accurately. After resection, and before the tissues are placed in formalin, the specimens are arranged by the surgeon into the correct position. Cyanoacrylate tissue glue is then applied to the two sections, which are opposed in their correct orientation, and the glue is allowed to dry (Fig. 1). The sample can then be placed in formalin. Cyanoacrylate does not alter the integrity of the tissue and leaves minimal artefacts on histological examination.1
Ethics statement/confirmation of patient’s permission Not required. Reference 1. Zeikus P, Dufresne R. Novel technique for use of cyanoacrylate in Mohs surgery. Dermatol Surg 2006;32:943–4.
W. Rodgers ∗ K. Mitsimponas K. Shakib Department of Oral & Maxillofacial Surgery, Royal Free Hospital NHS Trust, London, UK ∗ Corresponding author. E-mail address: [email protected] (W. Rodgers)
Fig. 1. Specimens oriented and joined together with cyanoacrylate tissue glue as indicated by the arrows. http://dx.doi.org/10.1016/j.bjoms.2017.05.020 0266-4356/© 2017 The British Association of Oral and Maxillofacial Surgeons. Published by Elsevier Ltd. All rights reserved.
Please cite this article in press as: Rodgers W, et al. Use of cyanoacrylate tissue adhesive to orientate histopathological specimens. Br J Oral Maxillofac Surg (2017), http://dx.doi.org/10.1016/j.bjoms.2017.05.020