Vasopressin and oxytosin receptors

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L368899: 1-(~~7,7-d~methyl-Z(~)-2(s)-amin~~methyJs~lp~o~yl)but~ram~Jo)b~c~rlo12.2.lJ-heptan-l(sj-yl]methylsulphon~~~~2-methylphenyl) piperujnr OPC31260: 5-d~mcthylamino-l-(Q-[2-methylbenzoylamino]benro~I)-2,3,4,5-tetrahydro-1H-benrazepine SR49059: ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~

Chemical names

Reviews 9 Barberis, C. and Tribollet, E. Vasopressin and oxytocin in the central nen-ous system Wt. /W. h&w&i& (in press) l Hruby, V. J. et al. {1990) Conforrnational and structural considerations in orytocin-receptor binding and biological activity AWII~.ROT.Pirontlacol.TX-icol.30,501-534 l LAszlo, F. 0. ef al. (1991) Pharmacobgy and clinical perspectkrs of saqxessin antagonists Plwrsmrol. J&t. 43,73-108 9 Lolait, S. I. r! RI. ‘JN5) Molecular biology of vawpressin receptors Au)!. NI- Acad. Sri. 7X,273-292

References 1. Williams, I? D. ef a!. (1994) I. Md. Chm. 37,565571 2. Jnnamorati, G. et al. BiachPm. 1. (in press) 3. LoJait, S. J. rt nl. (1995) PM. Nat! Acad. Sri. USA 92,6783-6787 4. Saito, M. et al. (1995) Ehchem. Biophys. Res. Commun. 212,751-757

Endogenous ligands: oxytocin (OT), arginine vasopressin (VP)