- Email: [email protected]
Vectors: A survey of molecular cloning vectors and their uses
review
T I G - October 1988, Vol. 4, no. 10 11 Papkoff, J., Brown, A. M. C. and Varmus, H. E. (1987) Mol. Cell. Biol. 7, 3978-3984 12 Brown, A. M. C., Wildin, R. S., Prendergast, T. J. and Varmus, H. E. (1986) Cell 46, 1001-1009 13 Rijsewijk, F. etaL (1987)EMBO]. 6, 127-131 14 Van Ooyea, A., Kwee, V. and Nusse, R. (1985) E M B O J. 4, 2905-2909 25 Rijsewijk, F. et al. (198,") Cell 50, 649-657 16 Wainwright, B. J. etal. (1988)EMBOJ. 7, 1743-1748 17 Dickson, C. and Peters, G. (1987)N~ture326, 833 18 T ~ a , M. et aL (1987) Proc. Nail Aead. Sd. USA 84, 2980-2984 19 Delli Bovi, P. et al. (1987) Cell 50, 729--737 20 Jakobovits, A., Shacldeford, G. M., Varmus, H. E. and Martin, G. R. (1986) Proc. Natl Aead. 8d. USA 83, 7806-7810 21 Shacldeford, G. M. and Varmus, H. E. (1987) Cell 50, 89-95 22 Willdnann, D. G., Bailes, J. A. and McMahon, A. P. (1987) Cell 5O, 79--88 23 Jones-Villeneuve, E. M. V., McBurney, M. W., Rogers, K. A. and Kalnins, V. I. (1983)J. Cell. Biol. 94, 253-262 24 Smith, R., Peters, G. and Dickson, C. (1988) E M B O J. 7,
1013-1022 Felix MitehnanCatalog of Ckromasome Aberrations in Cancor(3~ledn), AlanIL IAss,1988. $1f~.00(xxx~ + 1146 pages) ISBN 0 8451 4248 8.
25 Wilkinson, D. G., Peters, G., Dickson, C. and McMahon, A. P. (1988) E M B O J . 7, 691-695 26 Baker, N. E. (1987)EMBO]. 6, 1765--1773 27 Cabrera, C. V. et al. (1987) Cell 50, 659-663 28 Wieschaus, E. and Riggleman, R. (1987) Cell 49, 177-184 29 DiNardo, S. et aL (1988) Nature 332, 604-609 30 Gospodarowicz, D., Ferrara, N., Schweigerer, L. and Neufeld, G. (1987) Endocn'ne Rev. 8, 95-114 31 Slack, J. M. W., Darlington, B. G., Heath, J. K. and Godsave, S. F. (1987)Nature 326, 197-200 32 Weeks, D. L. and Melton, D. A. (1987) Cell 51, 861-867 33 Khnelman, D. and Kir~clmer, M. (1987) Cell 51, 869-877 34 Steward, R. (1987)Science 238, 692-694 35 Heine, U. I. etal. (1987))'. Cell. Biol. 105, 2861-2876 36 Sporn, M. B. and Roberts, A. B. (1988) Nature 332, 217~219 37 Perrimon, N. and Mahowald, A . P . (1987) Dev. Biol. 119, 587~600
R. Nusse is in the Division of Molecular Biology, The Netherlands Cancer Institute, (Antoni van Leeuwenheekhuis), Piesmanlaan 121, 1066 CX Amsterdam, The Netherlands.
books receivede
RayeLynneDippelandJ. ThomasHutton(eds) C a ~ Prometheus Books, 1988. $10.95 paperback $17.95 cloth 0d + 182 pages) ISBN 0 87975 427 3.
for @eA/ebe/mevP a ~
ErrolC. FfiedbergandPhilipC. Hanawalt(eds) DNA Repair Vol. 3: A l.aborat~y Manual of Research Procedu~m, Marcel Dekker, 1988. $125.00 (USA & Canada) $150.00 (a9 other countries) (x~di + 541 pages) ISBN 0 8247 7839 1.
Yun-FaiLau (ed.)Emf~-dne Genes;AnaykalMeguwls, ExpednuntalApproach~ andSelectedSystems. Oxford Univezsity press (USA). 1988. £30.00 @iii + 224 pages) ISBN 0 19 5O44O96.
P. H. Levine, D. V. Ablashi, M. Nonoyama, G. R. Pearson and IL Glaser(eds) Epstdn-Barr Vires and Human D/sease,HumaesPress, 1987. £69.05 (xmd+ 530 pages) ISBN 0 8960~ 130 6.
RobinM. Winter,SimonA. S. Knowles,Frederick R. BieberandMichael~ TheMalformedFetus and St//lb/gh A D/asmos~ Approach,JohnWiJey& Sons, 1988. £75.00 (vi + 317 pages) ISBN 0 471 90946 7.
Y~al Kolfin esd MichaelJ. Leihnwitz (eds) Viruses of F u j i amlSimpl¢ E u k a ~ , Marcel Dekker, 1988. $125.00 (USA & Canada) $150.00 (other countries) (xviii + 434 pages) ISBN 0 8247 7890 1.
GunterOhnandArminBasler(eds)Cytogenetles:Basic a m I A p p l i c d ~ , SpringerVerlag, 1987. DM.198
W. S. Hoarand D. J. Randall(eds) Fish Physiolo~ Vol. XI: ThePhysiolawofDevelopingFisb, AcadenficPress, 1988. $89.00 (rod+ 546 pages) ISBN 0 12 350433 3
Saran A. Narang (e@) Synthesis and Applications of DNA andRNA, Aesdemicpress, 1987. $45.00 (xv + 237 pages) ISBN 0 12 514030 4.
(I + 401 pages) ISBIq3 540 18017 6.
IL KevmHunt (e@) Current Topics in Developmental Biol@y Vo!21: NeuraI DevelopmentPart IV: Cellular and Molecularlh'fforentiation, AcademicPress, 1987. $55.00 0di + 441 pages) ISBN 0 12 153121 X. K. G. Adiyodiand R. G. Adiyo~ (eds) Reproductive Biola~ oflnvotebrates VoL II1: AccessorySex Glands, JohnWdey& Sons, 1988. £70.00 (x~iii+ 518 pages) ISBN 0 471 91466 5.
JohnG. Scandalies(ed.) MolecularGeneticso/Development(Advances in Genetics VoL 24), AcademicPress, 1987. $75.00 (x~d+ 529 pages) ISBN0 12 017624 6. Gmmar van HeYyneSequence Analysis in Molecular Biolo~: Treasure Trove or Tffvial Pursuit, Acaden@ Press, 1987. $27.00 (xii + 188 pages) ISBN 0 12 725130 8.
book rev,e
Vectorology, presentand future Vectors: A Survey of Molecular Cloning Vectors and Their U s e s edited by Raymond L. Rodriguez and David T. Denhardt, Butterworth, 1988.
£40.00 (ziv + 578 pages) ISBN 0 409 90042 7 This book is one of the volumes from the Biotechnology Series edited by J. E. Davies. It is dedicated not only to scientists using vectors as a tool for their research but also to those who are directly involved in development of new vectors as well as in modification of existing ones for new uses. The book is divided ir~to four parts. Part one contains four sections, discussing general cloning vectors for Gramnegative bacteria, specialized cloning vectors with broad-host-range capability, and cloning vectors for Gram-positive bacteria. Part two is dedicated to fungal cloning vectors, part three to insect and animal cell cloning vectors, and part four to plant cloning vectors. The 27 chapters
are written by specialists from all over the world who are directly involved in construction and exploitation of the hostvector systems descfibe~]~ In 1985, P. H. Pouwels, B. E. EngerValk and W.J. Brammar published a laboratory manual called 'Cloning Vectors' (Elsevier Science Publishers), which is a compilation of currently existing vectors used in cloning. That compendium is being constantly updated and is intended to be a source for rapid identification of plasmids and easy selection of a suitable vector for any particular purpose. On the other hand, the book by Rodriguez and Denhardt presents many different types of vectors in multi-faceted perspective. The book permits easy identification of various vectors either in the index, where all of them are listed, or by consulting the wellarranged tables in various chapters. The many figures included are very helpful in understanding not only the structure of each plasmid but also its function. In most
I
of the chapters, one car. find a discussion on the advantages of the vector as we9 as its disadvantages and limitations. Especially interesting are the parts of the chapters dedicated to future designs of molecular cloning vectors and properties which the ideal supervector should possess.
The authors provide the reader with fascinating glimpses of the 'evolution' of vectors from very simple ones to the ~mst sophisticated types. One is left with the impression that there is still an open field for researchers to become involved in vector construction or improvement. In some of the chapters, possible improvements and future needs are extensively discussed. The book is nicely arranged and well edited. It would be a very helpful addition to many libraries and should be found on the desks of all scientists who use recombinant DNA techniques. ANNA J. PODHAJSKA Department of Microbiology, University of Gdafzsk, ui. Kladki 24, 80-822 Gdagsk, Poland.
®
T I G - October 1988, Vol. 4, no. 10 11 Papkoff, J., Brown, A. M. C. and Varmus, H. E. (1987) Mol. Cell. Biol. 7, 3978-3984 12 Brown, A. M. C., Wildin, R. S., Prendergast, T. J. and Varmus, H. E. (1986) Cell 46, 1001-1009 13 Rijsewijk, F. etaL (1987)EMBO]. 6, 127-131 14 Van Ooyea, A., Kwee, V. and Nusse, R. (1985) E M B O J. 4, 2905-2909 25 Rijsewijk, F. et al. (198,") Cell 50, 649-657 16 Wainwright, B. J. etal. (1988)EMBOJ. 7, 1743-1748 17 Dickson, C. and Peters, G. (1987)N~ture326, 833 18 T ~ a , M. et aL (1987) Proc. Nail Aead. Sd. USA 84, 2980-2984 19 Delli Bovi, P. et al. (1987) Cell 50, 729--737 20 Jakobovits, A., Shacldeford, G. M., Varmus, H. E. and Martin, G. R. (1986) Proc. Natl Aead. 8d. USA 83, 7806-7810 21 Shacldeford, G. M. and Varmus, H. E. (1987) Cell 50, 89-95 22 Willdnann, D. G., Bailes, J. A. and McMahon, A. P. (1987) Cell 5O, 79--88 23 Jones-Villeneuve, E. M. V., McBurney, M. W., Rogers, K. A. and Kalnins, V. I. (1983)J. Cell. Biol. 94, 253-262 24 Smith, R., Peters, G. and Dickson, C. (1988) E M B O J. 7,
1013-1022 Felix MitehnanCatalog of Ckromasome Aberrations in Cancor(3~ledn), AlanIL IAss,1988. $1f~.00(xxx~ + 1146 pages) ISBN 0 8451 4248 8.
25 Wilkinson, D. G., Peters, G., Dickson, C. and McMahon, A. P. (1988) E M B O J . 7, 691-695 26 Baker, N. E. (1987)EMBO]. 6, 1765--1773 27 Cabrera, C. V. et al. (1987) Cell 50, 659-663 28 Wieschaus, E. and Riggleman, R. (1987) Cell 49, 177-184 29 DiNardo, S. et aL (1988) Nature 332, 604-609 30 Gospodarowicz, D., Ferrara, N., Schweigerer, L. and Neufeld, G. (1987) Endocn'ne Rev. 8, 95-114 31 Slack, J. M. W., Darlington, B. G., Heath, J. K. and Godsave, S. F. (1987)Nature 326, 197-200 32 Weeks, D. L. and Melton, D. A. (1987) Cell 51, 861-867 33 Khnelman, D. and Kir~clmer, M. (1987) Cell 51, 869-877 34 Steward, R. (1987)Science 238, 692-694 35 Heine, U. I. etal. (1987))'. Cell. Biol. 105, 2861-2876 36 Sporn, M. B. and Roberts, A. B. (1988) Nature 332, 217~219 37 Perrimon, N. and Mahowald, A . P . (1987) Dev. Biol. 119, 587~600
R. Nusse is in the Division of Molecular Biology, The Netherlands Cancer Institute, (Antoni van Leeuwenheekhuis), Piesmanlaan 121, 1066 CX Amsterdam, The Netherlands.
books receivede
RayeLynneDippelandJ. ThomasHutton(eds) C a ~ Prometheus Books, 1988. $10.95 paperback $17.95 cloth 0d + 182 pages) ISBN 0 87975 427 3.
for @eA/ebe/mevP a ~
ErrolC. FfiedbergandPhilipC. Hanawalt(eds) DNA Repair Vol. 3: A l.aborat~y Manual of Research Procedu~m, Marcel Dekker, 1988. $125.00 (USA & Canada) $150.00 (a9 other countries) (x~di + 541 pages) ISBN 0 8247 7839 1.
Yun-FaiLau (ed.)Emf~-dne Genes;AnaykalMeguwls, ExpednuntalApproach~ andSelectedSystems. Oxford Univezsity press (USA). 1988. £30.00 @iii + 224 pages) ISBN 0 19 5O44O96.
P. H. Levine, D. V. Ablashi, M. Nonoyama, G. R. Pearson and IL Glaser(eds) Epstdn-Barr Vires and Human D/sease,HumaesPress, 1987. £69.05 (xmd+ 530 pages) ISBN 0 8960~ 130 6.
RobinM. Winter,SimonA. S. Knowles,Frederick R. BieberandMichael~ TheMalformedFetus and St//lb/gh A D/asmos~ Approach,JohnWiJey& Sons, 1988. £75.00 (vi + 317 pages) ISBN 0 471 90946 7.
Y~al Kolfin esd MichaelJ. Leihnwitz (eds) Viruses of F u j i amlSimpl¢ E u k a ~ , Marcel Dekker, 1988. $125.00 (USA & Canada) $150.00 (other countries) (xviii + 434 pages) ISBN 0 8247 7890 1.
GunterOhnandArminBasler(eds)Cytogenetles:Basic a m I A p p l i c d ~ , SpringerVerlag, 1987. DM.198
W. S. Hoarand D. J. Randall(eds) Fish Physiolo~ Vol. XI: ThePhysiolawofDevelopingFisb, AcadenficPress, 1988. $89.00 (rod+ 546 pages) ISBN 0 12 350433 3
Saran A. Narang (e@) Synthesis and Applications of DNA andRNA, Aesdemicpress, 1987. $45.00 (xv + 237 pages) ISBN 0 12 514030 4.
(I + 401 pages) ISBIq3 540 18017 6.
IL KevmHunt (e@) Current Topics in Developmental Biol@y Vo!21: NeuraI DevelopmentPart IV: Cellular and Molecularlh'fforentiation, AcademicPress, 1987. $55.00 0di + 441 pages) ISBN 0 12 153121 X. K. G. Adiyodiand R. G. Adiyo~ (eds) Reproductive Biola~ oflnvotebrates VoL II1: AccessorySex Glands, JohnWdey& Sons, 1988. £70.00 (x~iii+ 518 pages) ISBN 0 471 91466 5.
JohnG. Scandalies(ed.) MolecularGeneticso/Development(Advances in Genetics VoL 24), AcademicPress, 1987. $75.00 (x~d+ 529 pages) ISBN0 12 017624 6. Gmmar van HeYyneSequence Analysis in Molecular Biolo~: Treasure Trove or Tffvial Pursuit, Acaden@ Press, 1987. $27.00 (xii + 188 pages) ISBN 0 12 725130 8.
book rev,e
Vectorology, presentand future Vectors: A Survey of Molecular Cloning Vectors and Their U s e s edited by Raymond L. Rodriguez and David T. Denhardt, Butterworth, 1988.
£40.00 (ziv + 578 pages) ISBN 0 409 90042 7 This book is one of the volumes from the Biotechnology Series edited by J. E. Davies. It is dedicated not only to scientists using vectors as a tool for their research but also to those who are directly involved in development of new vectors as well as in modification of existing ones for new uses. The book is divided ir~to four parts. Part one contains four sections, discussing general cloning vectors for Gramnegative bacteria, specialized cloning vectors with broad-host-range capability, and cloning vectors for Gram-positive bacteria. Part two is dedicated to fungal cloning vectors, part three to insect and animal cell cloning vectors, and part four to plant cloning vectors. The 27 chapters
are written by specialists from all over the world who are directly involved in construction and exploitation of the hostvector systems descfibe~]~ In 1985, P. H. Pouwels, B. E. EngerValk and W.J. Brammar published a laboratory manual called 'Cloning Vectors' (Elsevier Science Publishers), which is a compilation of currently existing vectors used in cloning. That compendium is being constantly updated and is intended to be a source for rapid identification of plasmids and easy selection of a suitable vector for any particular purpose. On the other hand, the book by Rodriguez and Denhardt presents many different types of vectors in multi-faceted perspective. The book permits easy identification of various vectors either in the index, where all of them are listed, or by consulting the wellarranged tables in various chapters. The many figures included are very helpful in understanding not only the structure of each plasmid but also its function. In most
I
of the chapters, one car. find a discussion on the advantages of the vector as we9 as its disadvantages and limitations. Especially interesting are the parts of the chapters dedicated to future designs of molecular cloning vectors and properties which the ideal supervector should possess.
The authors provide the reader with fascinating glimpses of the 'evolution' of vectors from very simple ones to the ~mst sophisticated types. One is left with the impression that there is still an open field for researchers to become involved in vector construction or improvement. In some of the chapters, possible improvements and future needs are extensively discussed. The book is nicely arranged and well edited. It would be a very helpful addition to many libraries and should be found on the desks of all scientists who use recombinant DNA techniques. ANNA J. PODHAJSKA Department of Microbiology, University of Gdafzsk, ui. Kladki 24, 80-822 Gdagsk, Poland.
®