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Vicarious Excretion of Intravascular Contrast Material
Vol. 100, Nov. Printed in U.S.A.
THE JOURNAL OF UROLOGY
Copyright © 1968 by The Williams & Wilkins Co.
VICARIOUS EXCRETION OF INTRA VASCULAR CONTRAST MATERIAL WILLIAM F. BARRY, JR.
AND
SAMUELE. FORBIS, JR.
From the Department of Radiology, Duke University Medical Center, Durham, North Carolina
With the increased use of angiography and drip infusion urography, larger amounts of contrast material are being injected into the bloodstream. As much as 150 cc of 50 per cent diatrizoate compounds may be injected for the study. The mode of excretion of this material was not established in patients with decreased renal function until the report of Chamberlain. 1
patients in the gallbladder, small bowel or colon (see figure). Visualization of the contrast material in the gastrointestinal (GI) tract occurred 24 to 48 hours after injection. In the patients having contrast material in the gastrointestinal tract, the blood urea nitrogen (DUN) levels were all elevated, varying from 42 to 110. Complete lack of visualization of contrast material in the uro-
A, 2-minute film after drip infusion urogram. Note hydronephrosis on right, no visualization on left. B, anteroposterior abdomen taken 48 hours after infusion urogram as part of left retrograde pyelogram.
Note contrast material in small bowel, colon and gallbladder. We have recently reviewed 100 drip infusion urograms to verify the findings in human studies. Of the 100 cases, 19 patients had delayed films of the abdomen 1 to 3 days following the injection. Of these, 5 cases were followed in order to visualize the excretion of contrast material. Visualization of contrast material was noted in 11 Accepted for publication January 20, 1968. Supported in part by United States Public Health Service AM 11192-01. 1 Chamberlain, M. J. and Sherwood, T.: The extra-renal excretion of diatrizoate in renal failure. Brit. J. Radio!., 39: 765-770, 1966.
genital tract could not be correlated with subsequent GI tract excretion. There were 8 patients who had films taken 24 to 48 hours after drip infusion pyelography but did not show contrast material in the GI tract. In these patients the BUN varied from 40 to 108. Therefore, of the 100 studies reviewed, sufficient films were taken in 19 patients. With approximately equal DUN range, only 58 per cent (11/19) had excretion of contrast material through the GI tract. 704
THE JOURNAL OF UROLOGY
Copyright © 1968 by The Williams & Wilkins Co.
VICARIOUS EXCRETION OF INTRA VASCULAR CONTRAST MATERIAL WILLIAM F. BARRY, JR.
AND
SAMUELE. FORBIS, JR.
From the Department of Radiology, Duke University Medical Center, Durham, North Carolina
With the increased use of angiography and drip infusion urography, larger amounts of contrast material are being injected into the bloodstream. As much as 150 cc of 50 per cent diatrizoate compounds may be injected for the study. The mode of excretion of this material was not established in patients with decreased renal function until the report of Chamberlain. 1
patients in the gallbladder, small bowel or colon (see figure). Visualization of the contrast material in the gastrointestinal (GI) tract occurred 24 to 48 hours after injection. In the patients having contrast material in the gastrointestinal tract, the blood urea nitrogen (DUN) levels were all elevated, varying from 42 to 110. Complete lack of visualization of contrast material in the uro-
A, 2-minute film after drip infusion urogram. Note hydronephrosis on right, no visualization on left. B, anteroposterior abdomen taken 48 hours after infusion urogram as part of left retrograde pyelogram.
Note contrast material in small bowel, colon and gallbladder. We have recently reviewed 100 drip infusion urograms to verify the findings in human studies. Of the 100 cases, 19 patients had delayed films of the abdomen 1 to 3 days following the injection. Of these, 5 cases were followed in order to visualize the excretion of contrast material. Visualization of contrast material was noted in 11 Accepted for publication January 20, 1968. Supported in part by United States Public Health Service AM 11192-01. 1 Chamberlain, M. J. and Sherwood, T.: The extra-renal excretion of diatrizoate in renal failure. Brit. J. Radio!., 39: 765-770, 1966.
genital tract could not be correlated with subsequent GI tract excretion. There were 8 patients who had films taken 24 to 48 hours after drip infusion pyelography but did not show contrast material in the GI tract. In these patients the BUN varied from 40 to 108. Therefore, of the 100 studies reviewed, sufficient films were taken in 19 patients. With approximately equal DUN range, only 58 per cent (11/19) had excretion of contrast material through the GI tract. 704