- Email: [email protected]
Vinegar Sock Soak for Tinea Pedis or Onychomycosis
Accepted Manuscript Vinegar Sock Soak for Tinea Pedis or Onychomycosis Steven Kelly, BS, Deede Liu, MD, Tang Wang, MD, PhD, Anand Rajpara, MD, Catherine Franano, Daniel Aires, MD PII:
S0190-9622(17)32448-9
DOI:
10.1016/j.jaad.2017.09.043
Reference:
YMJD 12016
To appear in:
Journal of American Dermatology
Received Date: 28 July 2017 Revised Date:
8 September 2017
Accepted Date: 13 September 2017
Please cite this article as: Kelly S, Liu D, Wang T, Rajpara A, Franano C, Aires D, Vinegar Sock Soak for Tinea Pedis or Onychomycosis, Journal of American Dermatology (2017), doi: 10.1016/ j.jaad.2017.09.043. This is a PDF file of an unedited manuscript that has been accepted for publication. As a service to our customers we are providing this early version of the manuscript. The manuscript will undergo copyediting, typesetting, and review of the resulting proof before it is published in its final form. Please note that during the production process errors may be discovered which could affect the content, and all legal disclaimers that apply to the journal pertain.
ACCEPTED MANUSCRIPT 1 Title Page Article Type: Therapeutic Pearl Title: Vinegar Sock Soak for Tinea Pedis or Onychomycosis
RI PT
Steven Kelly, BS1, Deede Liu, MD2, Tang Wang, MD, PhD2, Anand Rajpara, MD2, Catherine Franano3, Daniel Aires, MD2 1
University of Central Florida College of Medicine, Orlando, FL University of Kansas Medical Center, Kansas City, KS 3 Pembroke Hill High School, Kansas City, MO 2
M AN U
Daniel Aires, MD Division of Dermatology Department of Internal Medicine 4010 Wescoe Pavilion University of Kansas Medical Center 3901 Rainbow Blvd. Kansas City, KS 66160 Phone: (913)633-8063 Email: [email protected]
SC
Corresponding Author:
TE D
Funding Sources: This article has no funding source IRB Approval Status: Approval not required
Conflicts of Interest: The authors have no conflicts of interest to declare
EP
Reprint Requests: Daniel Aires Manuscript Word Count: 120 Abstract Word Count: 37 References: 2 Figures: 0 Tables: 0
AC C
1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42
Keywords: Tinea Pedis, Onychomycosis, Fungal Infection, Vinegar
ACCEPTED MANUSCRIPT 2 Vinegar Sock Soak for Tinea Pedis and/or Onychomycosis
43 Therapeutic Challenge
45
Onychomycosis and tinea pedis are exceedingly common conditions experienced by patients. In addition
46
to itch and cosmetic concerns, they increase the risk of cellulitis and diabetic foot ulcers1. While nightly
47
50/50 vinegar soaks can increase efficacy of topical antifungals due to fungicidal effects of acidic pH2,
48
the inconvenience of tub soaks limits compliance.
SC
49 50
M AN U
51 52 53 54
59 60 61 62 63 64 65 66
EP
58
AC C
57
TE D
55 56
RI PT
44
ACCEPTED MANUSCRIPT 3 Solution
68
Each evening, patients go to a bathroom or other place with a vinegar-resistant floor, don old cotton
69
socks, pour a few spoons of plain or apple-cider vinegar and a few spoons of water over the toes, and sit
70
and read for 10-15 minutes. They then doff the socks, apply topical antifungals, and go to bed. In our
71
experience, compliance, efficacy, and satisfaction are high with most patients achieving complete
72
clinical responses within a year.
RI PT
67
SC
73 74
M AN U
75 76 77 78
82 83 84 85 86 87 88 89 90
EP
81
AC C
80
TE D
79
ACCEPTED MANUSCRIPT 4 91
References
92
1.
94 95
Physician. 2013;88(11):762-770. 2.
Sleven R, Lanckacker E, Delputte P, et al. Evaluation of topical antifungal products in an in vitro onychomycosis model. Mycoses. 2016;59(5):327-330.
AC C
EP
TE D
M AN U
SC
96
RI PT
93
Westerberg DP, Voyack MJ. Onychomycosis: Current trends in diagnosis and treatment. Am Fam
S0190-9622(17)32448-9
DOI:
10.1016/j.jaad.2017.09.043
Reference:
YMJD 12016
To appear in:
Journal of American Dermatology
Received Date: 28 July 2017 Revised Date:
8 September 2017
Accepted Date: 13 September 2017
Please cite this article as: Kelly S, Liu D, Wang T, Rajpara A, Franano C, Aires D, Vinegar Sock Soak for Tinea Pedis or Onychomycosis, Journal of American Dermatology (2017), doi: 10.1016/ j.jaad.2017.09.043. This is a PDF file of an unedited manuscript that has been accepted for publication. As a service to our customers we are providing this early version of the manuscript. The manuscript will undergo copyediting, typesetting, and review of the resulting proof before it is published in its final form. Please note that during the production process errors may be discovered which could affect the content, and all legal disclaimers that apply to the journal pertain.
ACCEPTED MANUSCRIPT 1 Title Page Article Type: Therapeutic Pearl Title: Vinegar Sock Soak for Tinea Pedis or Onychomycosis
RI PT
Steven Kelly, BS1, Deede Liu, MD2, Tang Wang, MD, PhD2, Anand Rajpara, MD2, Catherine Franano3, Daniel Aires, MD2 1
University of Central Florida College of Medicine, Orlando, FL University of Kansas Medical Center, Kansas City, KS 3 Pembroke Hill High School, Kansas City, MO 2
M AN U
Daniel Aires, MD Division of Dermatology Department of Internal Medicine 4010 Wescoe Pavilion University of Kansas Medical Center 3901 Rainbow Blvd. Kansas City, KS 66160 Phone: (913)633-8063 Email: [email protected]
SC
Corresponding Author:
TE D
Funding Sources: This article has no funding source IRB Approval Status: Approval not required
Conflicts of Interest: The authors have no conflicts of interest to declare
EP
Reprint Requests: Daniel Aires Manuscript Word Count: 120 Abstract Word Count: 37 References: 2 Figures: 0 Tables: 0
AC C
1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42
Keywords: Tinea Pedis, Onychomycosis, Fungal Infection, Vinegar
ACCEPTED MANUSCRIPT 2 Vinegar Sock Soak for Tinea Pedis and/or Onychomycosis
43 Therapeutic Challenge
45
Onychomycosis and tinea pedis are exceedingly common conditions experienced by patients. In addition
46
to itch and cosmetic concerns, they increase the risk of cellulitis and diabetic foot ulcers1. While nightly
47
50/50 vinegar soaks can increase efficacy of topical antifungals due to fungicidal effects of acidic pH2,
48
the inconvenience of tub soaks limits compliance.
SC
49 50
M AN U
51 52 53 54
59 60 61 62 63 64 65 66
EP
58
AC C
57
TE D
55 56
RI PT
44
ACCEPTED MANUSCRIPT 3 Solution
68
Each evening, patients go to a bathroom or other place with a vinegar-resistant floor, don old cotton
69
socks, pour a few spoons of plain or apple-cider vinegar and a few spoons of water over the toes, and sit
70
and read for 10-15 minutes. They then doff the socks, apply topical antifungals, and go to bed. In our
71
experience, compliance, efficacy, and satisfaction are high with most patients achieving complete
72
clinical responses within a year.
RI PT
67
SC
73 74
M AN U
75 76 77 78
82 83 84 85 86 87 88 89 90
EP
81
AC C
80
TE D
79
ACCEPTED MANUSCRIPT 4 91
References
92
1.
94 95
Physician. 2013;88(11):762-770. 2.
Sleven R, Lanckacker E, Delputte P, et al. Evaluation of topical antifungal products in an in vitro onychomycosis model. Mycoses. 2016;59(5):327-330.
AC C
EP
TE D
M AN U
SC
96
RI PT
93
Westerberg DP, Voyack MJ. Onychomycosis: Current trends in diagnosis and treatment. Am Fam