Vitamin C, volume I

Vitamin C, volume I

Free Radical Biology & Medicine, Vol. 9, p. 267, 1990 0891-5849/90 $3.00 + .00 Copyright © 1990 PergamonPress plc Printed in the USA. All rights res...

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Free Radical Biology & Medicine, Vol. 9, p. 267, 1990

0891-5849/90 $3.00 + .00 Copyright © 1990 PergamonPress plc

Printed in the USA. All rights reserved.

Book Review Vitamin C, Volume I 318 pp., 1990. Price: $170.00 US, $199.50 Outside US V i t a m i n C, Volume H 236 pp., 1990. Price: $145.00 US, $170.00 Outside US

Vitamin C, Volume III 264 pp., 1990. Price: $150.00 US, $176.00 Outside US (50% discount on 3-volume set through 1990) C . A L A N B . CLEMENTSON, A u t h o r CRC Press, Inc., Boca Raton, FL, 1990 Reviewed by William A. Pryor Biodynamics Institute, Louisiana State University, Baton Rouge, LA 70803-1800, USA

infection. Volume HI covers the chemical changes associated with vitamin C deficiency and clinical changes associated with disorders in vitamin C metabolism. The chemical changes are discussed from a physician's viewpoint; the chemistry and biochemistry of vitamin C is, in general, discussed at only an elementary level in these volumes. The clinical aspects of vitamin C metabolism include rheumatic fever, wounds, effects of pregnancy, ulcers, ocular lesions, cerebral hemorrhage, and coronary thrombosis. These books are well put together with a clear style, many references, and a complete and easy-to-use index. Like other CRC volumes of this type, I think it is unfortunate that this work appears in three volumes rather than being bound into a single book. Most readers who want to buy one of these volumes will wind up buying all three, and the effect of having three volumes is simply to burden the reader with having to look through three different books to find the topic he wants and to deal with three separate indices. The total price of the three volumes is very high. Even with the 50% discount in effect through 1990, the three volumes cost $247.00. In summary, these three volumes are highly recommended as a critical and reasonably complete review of the medical and medically-oriented biochemical aspects of vitamin C.

This is a thorough and quite complete review of the medical aspects of the uses of vitamin C in humans, its interaction with other dietary components, and the medical effects of vitamin C deficiency. The author has a lucid style and the language is direct and easy to follow. Many tables and figures from the original literature are reproduced, which is a great convenience to the reader. The books are copyrighted in 1989, but the author remarks in his Preface that the book was written over a 36-month period, so some of the earlier chapters are not as up-to-date as the later chapters. The later chapters include references through 1988. The author is a physician trained in obstetrics and gynecology who has a positive attitude toward supplementation of humans with vitamin C. While the review is fairly even-handed, the author does bring to most of his writing his positive view of vitamin C supplementation in humans. The broad outline of these three volumes is as follows: Volume I covers vitamin C deficiency and a lengthy review of those factors that affect the pharmacokinetics of vitamin C. Factors such as smoking, age, sex, infection, surgery, intake of metals and protein, pregnancy, stress, ionizing radiation, and a number of other environmental factors are considered. Volume II treats the clinical and pathological results of vitamin C deficiency. Topics covered include diabetes, anemia, wound healing, dental changes, atherosclerosis, and 267