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Vivascience expands Vivapure product range
8
New products
8 Filtration+Separation May 2005
Vivascience expands Vivapure product range Vivascience, a subsidiary of Germany company Sartorius AG, has further expanded its Vivapure sample preparation product line by launching a new human albumin and IgG depletion kit. The Vivapure Anti-HSA/IgG Kit uses a combination of a anti-HSA antibody fragment and Protein G resin for specifically depleting albumin and IgG from human samples. It provides in excess of 95% removal of albumin and IgG from 20 mu l of human serum, along with low non-specific binding of potential serum biomarkers. Albumin and IgG depleted samples are recovered in a low salt buffer, facilitating
downstream applications. The method is quick, suitable for parallel processing and offered in a ready-to-use kit. The kit further improves the resolution and detection of lower abundance sample proteins by electrophoresis, chromatography and mass spectrometry by removing up to 75% of high abundant serum proteins, says Vivascience. The anti-HSA ligand also shows reactivity against rat and mouse albumin. As Protein G is also efficient at binding rat and mouse IgG, this kit can be utilised for processing samples from the three most frequently encountered sample sources in biomarker research.
The Vivapure Anti-HSA/IgG Kit contains Anti-HSA/IgG affinity resin, centrifugal columns, which can be filled individually with the resin, micro-centrifuge tubes, and binding buffer for preparing 12 serum samples. The spin column format allows a single sample to be processed within 20 minutes. The company says that by introducing this kit, it is expanding its range of Vivapure sample preparation products, including the Vivapure AntiHSA kit for albumin depletion; Vivapure Anti-HSA resin for albumin depletion from serum volumes up to 400 mu l; and Vivapure ion exchange spin columns for sample fractionation.
UF cartridge reduces footprint size/capital costs KMS’ (Wilmington, Massachusetts, USA,) PMPW-10 ultrafiltration (UF) cartridge for potable water treatment.is nowCertified NSF-
61 compliant, the hollow-fibre cartridge is 25 cm (10 inch) in diameter and contains 60% more membrane area and provides 60% more product water than its 20 cm (8 inch) predecessor, resulting in significant cost savings for municipal water treatment plants, says the company. The greater output of the cartridge enables systems with fewer skids to be created, reducing plant floor
space requirements by up to 50%. For new plants, the smaller footprint produces dramatic reductions in building and installation costs. Existing plants can expand capacity by converting from 20 cm (8 inch) cartridges to the PMPW-10 cartridge, without having to extend buildings or construct new ones, says KMS. The cartridge’s hollow fibre UF membranes have a nominal molecular weight cut-off of 100 000. Compliance with the Safe Drinking Water Act is assured because the membranes consistently exceed 4-log removal of Cryptosporidium, Giardia and viruses. Additionally, the fibres have demonstrated the ability to reduce turbidity to less than 0.1 NTU.
Nano-structure media improve filtration Catalyx Inc of Brea, California, USA, which specializes in developing new technologies with an emphasis on water treatment and energy, has introduced what it describes as high-performance, lowcost filtration systems. The HEM filtration systems consist of filter media that have a
porous yet tough nano-structure. According to Catalyx, field tests have shown the back-washable media to consistently filter in the 15m range. Furthermore, because of its good turbidity removal performance (sludge density index of less than 1.0), its use means that it is not necessary to
include the cartridge pre-filtration stage in reverse osmosis plants. The company says that the systems offer many advantages over conventional sand/multimedia systems, including higher flow velocity, resulting in a smaller footprint; a lower pressure drop; and a high dirt-holding capacity.
Polyurethane scroll for Centriquip decanters Centriquip, the UK’s largest decanter centrifuge manufacturer, has developed a polyurethane scroll for its machines. According to the company, the scroll is lighter, more hardwearing and less expensive than all-steel scrolls and can increase performance, reduce noise levels, lower costs and improve the working environment at a single stroke. The scroll, which is the heart of the decanter centrifuge, continuously removes solids that have been separated and sedimented inside the bowl by the high G force. The polyurethane scroll has a steel core but is still much lighter than all-steel scrolls allowing the unit to rotate much faster without any risk of vibration and with reduced wear on bearings; it is much harder wearing than steel when used with most materials so it will last longer between services – according to Centriquip, at least twice as long. It can run much quieter to improve the working environment within the plant. The polyurethane scroll is much faster to make in the workshop, the company says – typically one week turnaround rather than six weeks for a steel unit. This can reduce significantly the down time for plants especially during unplanned maintenance. The polyurethane scroll is currently available for selected Centriquip models and can also be retrofitted to existing machines.
New products
8 Filtration+Separation May 2005
Vivascience expands Vivapure product range Vivascience, a subsidiary of Germany company Sartorius AG, has further expanded its Vivapure sample preparation product line by launching a new human albumin and IgG depletion kit. The Vivapure Anti-HSA/IgG Kit uses a combination of a anti-HSA antibody fragment and Protein G resin for specifically depleting albumin and IgG from human samples. It provides in excess of 95% removal of albumin and IgG from 20 mu l of human serum, along with low non-specific binding of potential serum biomarkers. Albumin and IgG depleted samples are recovered in a low salt buffer, facilitating
downstream applications. The method is quick, suitable for parallel processing and offered in a ready-to-use kit. The kit further improves the resolution and detection of lower abundance sample proteins by electrophoresis, chromatography and mass spectrometry by removing up to 75% of high abundant serum proteins, says Vivascience. The anti-HSA ligand also shows reactivity against rat and mouse albumin. As Protein G is also efficient at binding rat and mouse IgG, this kit can be utilised for processing samples from the three most frequently encountered sample sources in biomarker research.
The Vivapure Anti-HSA/IgG Kit contains Anti-HSA/IgG affinity resin, centrifugal columns, which can be filled individually with the resin, micro-centrifuge tubes, and binding buffer for preparing 12 serum samples. The spin column format allows a single sample to be processed within 20 minutes. The company says that by introducing this kit, it is expanding its range of Vivapure sample preparation products, including the Vivapure AntiHSA kit for albumin depletion; Vivapure Anti-HSA resin for albumin depletion from serum volumes up to 400 mu l; and Vivapure ion exchange spin columns for sample fractionation.
UF cartridge reduces footprint size/capital costs KMS’ (Wilmington, Massachusetts, USA,) PMPW-10 ultrafiltration (UF) cartridge for potable water treatment.is nowCertified NSF-
61 compliant, the hollow-fibre cartridge is 25 cm (10 inch) in diameter and contains 60% more membrane area and provides 60% more product water than its 20 cm (8 inch) predecessor, resulting in significant cost savings for municipal water treatment plants, says the company. The greater output of the cartridge enables systems with fewer skids to be created, reducing plant floor
space requirements by up to 50%. For new plants, the smaller footprint produces dramatic reductions in building and installation costs. Existing plants can expand capacity by converting from 20 cm (8 inch) cartridges to the PMPW-10 cartridge, without having to extend buildings or construct new ones, says KMS. The cartridge’s hollow fibre UF membranes have a nominal molecular weight cut-off of 100 000. Compliance with the Safe Drinking Water Act is assured because the membranes consistently exceed 4-log removal of Cryptosporidium, Giardia and viruses. Additionally, the fibres have demonstrated the ability to reduce turbidity to less than 0.1 NTU.
Nano-structure media improve filtration Catalyx Inc of Brea, California, USA, which specializes in developing new technologies with an emphasis on water treatment and energy, has introduced what it describes as high-performance, lowcost filtration systems. The HEM filtration systems consist of filter media that have a
porous yet tough nano-structure. According to Catalyx, field tests have shown the back-washable media to consistently filter in the 15
include the cartridge pre-filtration stage in reverse osmosis plants. The company says that the systems offer many advantages over conventional sand/multimedia systems, including higher flow velocity, resulting in a smaller footprint; a lower pressure drop; and a high dirt-holding capacity.
Polyurethane scroll for Centriquip decanters Centriquip, the UK’s largest decanter centrifuge manufacturer, has developed a polyurethane scroll for its machines. According to the company, the scroll is lighter, more hardwearing and less expensive than all-steel scrolls and can increase performance, reduce noise levels, lower costs and improve the working environment at a single stroke. The scroll, which is the heart of the decanter centrifuge, continuously removes solids that have been separated and sedimented inside the bowl by the high G force. The polyurethane scroll has a steel core but is still much lighter than all-steel scrolls allowing the unit to rotate much faster without any risk of vibration and with reduced wear on bearings; it is much harder wearing than steel when used with most materials so it will last longer between services – according to Centriquip, at least twice as long. It can run much quieter to improve the working environment within the plant. The polyurethane scroll is much faster to make in the workshop, the company says – typically one week turnaround rather than six weeks for a steel unit. This can reduce significantly the down time for plants especially during unplanned maintenance. The polyurethane scroll is currently available for selected Centriquip models and can also be retrofitted to existing machines.