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Wills Eye Hospital Conference
719
EDITORIALS
tainly there is no method at present to mini mize ocular damage when the eye is in volved. It would be hopeful to have a serologic test and an acceptable skin-testing antigen. Recent studies along this line have been en couraging (Woodruff et al, 1964; Woods et al, 1964) but they are still experimental and require further testing, evaluation and standardization. Hypergammaglobulinemia and eosinophilia should make one consider this dis order. It has been found that sera from some of these patients have rather high titers of anti-A and anti-B activity. This activity can be removed by absorption with emulsified adult Toxocara worms. Thus there exists the possibility that encysted Toxocara may act as stimuli to the produc tion of hemagglutinins (Heiner and Kevy, 1956). Vision is destroyed by these nematodes. Ophthalmologists are becoming aware of the importance of this entity. Diagnostic ability must be sharpened by reliable tests as well as an increased index of suspicion. Until therapy can be found and utilized success fully to prevent ocular invasion and destruc tion, attention must be directed to the res ervoir—the dogs, cats and particularly the puppy dogs. Frequent worming of these pets will reduce the number and chance of human contamination. Irving H. Leopold. REFERENCES
Ashton, N.: Brit. J . Ophth., 44:129, 1960. Beaver, P. C , et al.: Pediatrics, 12:491, 1953. Benedict, W . : T. Tennessee Μ. Α., 15 :328, 1958. Bourke, C. H., and Yeats, F. Μ.: M. J . Aus tralia, 2 : 1 2 , 1961. Braun-Vallon, S., Ashton Ν., Duguid, I. Μ., and Dhermy, P.: Ann. Ocul., 197:217-240, 1964. Chanduri, R. N., and Saha, Τ. K . : Lancet, 2 : 493, 1959. Collins, Ε. T.: Royal London Ophth. Hosp. Rep., 13:361, 1892. Ehrenford, F. Α . : Am. Γ. Trop. Med, 6:166, 1957. Heiner, D. C , and Kevy, S. V . : New Eng. J . Med., 254 :629, 1956.
Kogat, L., and Boniuk, M.: Tumors of the Eye and Adnexa, 1962, pp. 2, 507. Smith, Μ. Η. and Beaver, P. C.: Pediatrics, 12:491, 1953. Wilder, H. C.: Nematode endophthalmitis. Tr. Am. Acad. Ophth., 55 :99, 1950. Woodruff, A. W , and Thacker, C. Κ. H.: In fection with Animal Helminths. 1964, p. 10001. Zeuler, W., and Apt, L.: Am. J . Dis. Children, 78:153, 1949.
W I L L S EYE H O S P I T A L CONFERENCE The 17th annual clinical conference of the Wills Eye Hospital held in Philadelphia on February 18, 19 and 20 is now only a pleas ant memory but in the process it was excit ing, dramatic, informative and bustling. At tended by over 800 registrants, interest lagged for no one. Exhibits ranged from the scientific, such as Dr. Bedell's fundus pic tures, to the commercial. The receptions were gay and savory and, along with ladies' tour of colonial homes in Fairmount Park, were well attended. The Bedell Lecture was ably delivered by Dr. Donald J . Lyle of Cincinnati. He also participated in a neuro-ophthalmology sym posium along with Dr. Frank D. Carroll, Bernard J . Alpers, Nathan S. Schlezinger, Thomas R. Hedges, Jr., Phillip Levy and Philip Hughes. The traditional College of Physicians of Philadelphia, Section on Oph thalmology, lecture consisted of Dr. Car roll's experience with nutritional retrobulbar neuritis. The variety of topics covered in the formal papers extended from "Infrared photography in the diagnosis of orbital hemangioma" by Dr. Koven to "Pituitary stalk section in treatment of diabetic reti nopathy" by Drs. Hanno and Shenkin. Di verse ocular surgical procedures were pre sented by Drs. R. Ellis, O. R. Kline, Jr., C. D. F. Jensen, G. Shannon, M. Wolkowicz and C. D. Kelman. A symposium on corneal disease moder ated by Dr. W. E. Fry included Drs. P. G. Spaeth, R. D. Mulberger, T. Sery, O. R.
720
OBITUARY
Kline, J r , and J . Purnell. Dr. I. H. Leopold commented on a fine trio of papers con cerned with glaucoma and produced by Drs. A. Chan, R. Goldberg, E. U . Keates and G. L. Spaeth. Studies emanating from the Research De partment were presented by Drs. L. Sarin, N. Krishna, B. Mitchell, L. Huang, T. Sery and J . Hallett. Papers on the other miscel laneous subjects were read by Drs. W . R. Green, S. Blank, Ε. B. Spaeth, J . O'Rourke, W . H. Annesley, J r . , W . S . Tassman, S . Weiss, Ε. H. Bedrossian and P. Laibson. The closed circuit color television presenta tion of surgical procedures was supple mented with a demonstration by Drs. L. Sarin and R. Goldberg of the ultrasound diagnostic machine. Dr. W . E. F r y in a surprise ceremony was given a beautifully engraved silver tray W I L L I A M EVANS BRUNER for his many years of outstanding accom plishments at and services for the Wills Eye Clark in 1897. At Western Reserve Uni Hospital. versity he served as clinical assistant in oph Joseph W . Hallett. thalmology until 1912 when he became a clinical professor. In 1915, he was ap pointed professor of ophthalmology and OBITUARY chairman of the department, a position he W I L L I A M E V A N S BRUNER held until 1936. Dr. Bruner carried on a (1866-1964) large surgical and consultant practice until The death of Dr. Williams Evans Bruner his retirement in 1952. He was associated on September 3, 1964, in Cleveland, Ohio, for many years with his nephew, the late Dr. Abraham Bruner, who died in 1957. at the age of 98 years, concluded a long and distinguished career. He was born in Colum bia, Pennsylvania, on January 8, 1866. In 1888, he graduated with honors from Wesleyan University, Middletown, Connecticut, where he was elected to Phi Beta Kappa. Dr. Bruner received his medical degree from the University of Pennsylvania in 1891 and served as assistanet to Dr. George de Schweinetz until 1893. In addition to work at the Philadelphia General Hospital, he had training at the Philadelphia Poly clinic and at Jefferson Medical College. In January, 1894, Dr. Bruner moved to Cleveland where he began the practice of ophthalmology. He married Miss Lydia
Dr. W . E. Bruner was the author of nu merous papers on ophthalmologic subjects. He served as an associate editor of the AMERICAN
JOURNAL
OF
OPHTHALMOLOGY
and Annals of Ophthalmology. In World War Γ he held the rank of major in the Medical Corps of the Army and served in the office of the Surgeon General. He had been a member of the American Ophthalmological Society for 57 years, since his election in 1907. In 1913 he was a founder and fellow of The American Col lege of Surgeons and he was an early mem ber of the American Academy of Ophthal mology and Otolaryngology. Dr. Bruner
EDITORIALS
tainly there is no method at present to mini mize ocular damage when the eye is in volved. It would be hopeful to have a serologic test and an acceptable skin-testing antigen. Recent studies along this line have been en couraging (Woodruff et al, 1964; Woods et al, 1964) but they are still experimental and require further testing, evaluation and standardization. Hypergammaglobulinemia and eosinophilia should make one consider this dis order. It has been found that sera from some of these patients have rather high titers of anti-A and anti-B activity. This activity can be removed by absorption with emulsified adult Toxocara worms. Thus there exists the possibility that encysted Toxocara may act as stimuli to the produc tion of hemagglutinins (Heiner and Kevy, 1956). Vision is destroyed by these nematodes. Ophthalmologists are becoming aware of the importance of this entity. Diagnostic ability must be sharpened by reliable tests as well as an increased index of suspicion. Until therapy can be found and utilized success fully to prevent ocular invasion and destruc tion, attention must be directed to the res ervoir—the dogs, cats and particularly the puppy dogs. Frequent worming of these pets will reduce the number and chance of human contamination. Irving H. Leopold. REFERENCES
Ashton, N.: Brit. J . Ophth., 44:129, 1960. Beaver, P. C , et al.: Pediatrics, 12:491, 1953. Benedict, W . : T. Tennessee Μ. Α., 15 :328, 1958. Bourke, C. H., and Yeats, F. Μ.: M. J . Aus tralia, 2 : 1 2 , 1961. Braun-Vallon, S., Ashton Ν., Duguid, I. Μ., and Dhermy, P.: Ann. Ocul., 197:217-240, 1964. Chanduri, R. N., and Saha, Τ. K . : Lancet, 2 : 493, 1959. Collins, Ε. T.: Royal London Ophth. Hosp. Rep., 13:361, 1892. Ehrenford, F. Α . : Am. Γ. Trop. Med, 6:166, 1957. Heiner, D. C , and Kevy, S. V . : New Eng. J . Med., 254 :629, 1956.
Kogat, L., and Boniuk, M.: Tumors of the Eye and Adnexa, 1962, pp. 2, 507. Smith, Μ. Η. and Beaver, P. C.: Pediatrics, 12:491, 1953. Wilder, H. C.: Nematode endophthalmitis. Tr. Am. Acad. Ophth., 55 :99, 1950. Woodruff, A. W , and Thacker, C. Κ. H.: In fection with Animal Helminths. 1964, p. 10001. Zeuler, W., and Apt, L.: Am. J . Dis. Children, 78:153, 1949.
W I L L S EYE H O S P I T A L CONFERENCE The 17th annual clinical conference of the Wills Eye Hospital held in Philadelphia on February 18, 19 and 20 is now only a pleas ant memory but in the process it was excit ing, dramatic, informative and bustling. At tended by over 800 registrants, interest lagged for no one. Exhibits ranged from the scientific, such as Dr. Bedell's fundus pic tures, to the commercial. The receptions were gay and savory and, along with ladies' tour of colonial homes in Fairmount Park, were well attended. The Bedell Lecture was ably delivered by Dr. Donald J . Lyle of Cincinnati. He also participated in a neuro-ophthalmology sym posium along with Dr. Frank D. Carroll, Bernard J . Alpers, Nathan S. Schlezinger, Thomas R. Hedges, Jr., Phillip Levy and Philip Hughes. The traditional College of Physicians of Philadelphia, Section on Oph thalmology, lecture consisted of Dr. Car roll's experience with nutritional retrobulbar neuritis. The variety of topics covered in the formal papers extended from "Infrared photography in the diagnosis of orbital hemangioma" by Dr. Koven to "Pituitary stalk section in treatment of diabetic reti nopathy" by Drs. Hanno and Shenkin. Di verse ocular surgical procedures were pre sented by Drs. R. Ellis, O. R. Kline, Jr., C. D. F. Jensen, G. Shannon, M. Wolkowicz and C. D. Kelman. A symposium on corneal disease moder ated by Dr. W. E. Fry included Drs. P. G. Spaeth, R. D. Mulberger, T. Sery, O. R.
720
OBITUARY
Kline, J r , and J . Purnell. Dr. I. H. Leopold commented on a fine trio of papers con cerned with glaucoma and produced by Drs. A. Chan, R. Goldberg, E. U . Keates and G. L. Spaeth. Studies emanating from the Research De partment were presented by Drs. L. Sarin, N. Krishna, B. Mitchell, L. Huang, T. Sery and J . Hallett. Papers on the other miscel laneous subjects were read by Drs. W . R. Green, S. Blank, Ε. B. Spaeth, J . O'Rourke, W . H. Annesley, J r . , W . S . Tassman, S . Weiss, Ε. H. Bedrossian and P. Laibson. The closed circuit color television presenta tion of surgical procedures was supple mented with a demonstration by Drs. L. Sarin and R. Goldberg of the ultrasound diagnostic machine. Dr. W . E. F r y in a surprise ceremony was given a beautifully engraved silver tray W I L L I A M EVANS BRUNER for his many years of outstanding accom plishments at and services for the Wills Eye Clark in 1897. At Western Reserve Uni Hospital. versity he served as clinical assistant in oph Joseph W . Hallett. thalmology until 1912 when he became a clinical professor. In 1915, he was ap pointed professor of ophthalmology and OBITUARY chairman of the department, a position he W I L L I A M E V A N S BRUNER held until 1936. Dr. Bruner carried on a (1866-1964) large surgical and consultant practice until The death of Dr. Williams Evans Bruner his retirement in 1952. He was associated on September 3, 1964, in Cleveland, Ohio, for many years with his nephew, the late Dr. Abraham Bruner, who died in 1957. at the age of 98 years, concluded a long and distinguished career. He was born in Colum bia, Pennsylvania, on January 8, 1866. In 1888, he graduated with honors from Wesleyan University, Middletown, Connecticut, where he was elected to Phi Beta Kappa. Dr. Bruner received his medical degree from the University of Pennsylvania in 1891 and served as assistanet to Dr. George de Schweinetz until 1893. In addition to work at the Philadelphia General Hospital, he had training at the Philadelphia Poly clinic and at Jefferson Medical College. In January, 1894, Dr. Bruner moved to Cleveland where he began the practice of ophthalmology. He married Miss Lydia
Dr. W . E. Bruner was the author of nu merous papers on ophthalmologic subjects. He served as an associate editor of the AMERICAN
JOURNAL
OF
OPHTHALMOLOGY
and Annals of Ophthalmology. In World War Γ he held the rank of major in the Medical Corps of the Army and served in the office of the Surgeon General. He had been a member of the American Ophthalmological Society for 57 years, since his election in 1907. In 1913 he was a founder and fellow of The American Col lege of Surgeons and he was an early mem ber of the American Academy of Ophthal mology and Otolaryngology. Dr. Bruner