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Workshop proceedings: Immunological aspects of dental caries
DEPARTMENT
OF REVIEWS
AND ABSTRACTS
Edited by J. A. Salzmann, D.D.S. New York City All inquiries regarding information on reviews and abstracts should be directed to the respective authors. Articles or books for review in this department should be addressed to Dr. J. A. Salunarm, 25 Sutton Place South, New York, New York 10022.
Workshop Proceedings: Immunological Aspects of Dental Caries National Caries Program, National Institute of Dental Research, United States Public Health Service, published by Information Retrieval, Inc.. Arlington, Va.
On Jan. 8 and 9, 1976, the National Caries Program, National Institute of Dental Research (NIH), sponsored a workshop for the critical assessment of reports of in vitro and in vivo studies on the efficacy and feasibility of immunologic prevention of dental caries and for the discussion of candidate antigens as possible immunogens in a caries vaccine. The most important discovery in caries prevention has been the cariogenicity of Streptococcus mutans. This prompted the initiation of research studies involving immunization as an approach to caries prevention. Results of studies in animal models suggest that serum and/or secretory antibodies directed to S. mutans can be effective in reducing the population of S. mutans in plaques and thus reduce the incidence of dental caries. Mutan and lipoteichoic acid are two streptococcal antigens that require further exploration to determine their immunochemical and immunobiologic natures. Because mutan is an adhesive responsible for S. mutans infectivity, specific antibodies against this polymer may prevent colonization of oral surfaces. Initial immunoprophylaxis may have to be supplemented with a nonimmunologic method to reduce oral microflora.
Minor Tooth Movement in the Growing Child M. Michael Cohen, Sr., with contributions
by John I?. Orr, Jr., and Gerard Borell
Philadelphia, 1977, W. B. Saunders Company. 143 pages, illustrated. Price, $15.00
This volume deals with the recognition and treatment of minor occlusal disharmonies in the primary and early mixed dentitions. Chapters are included on appliance construction, radiography, and cephalometrics as they apply in pediatric dentistry. Radiography is explained and the text is accompanied by excellent illustrations provided by the Eastman Kodak Company. Cohen includes specific detailed instructions on radiographing the teeth of children in the deciduous, mixed, and permanent dentitions. The use of pantographic radiography is explained. The part on treatment is outlined in the twenty-five pages of text devoted to this subject. Cohen states that deep overbite in the deciduous dentition should be treated. It is generally accepted, however, that the arrangement of the permanent teeth depends on growth of the jaws rather than on lack of spacing in the deciduous dentition. In the absence of patient micromandibular development, it is difficult to diagnose inadequate arch length in the deciduous dentition period. Valuable information is provided on the handling of overretained deciduous incisors, which is little understood at present among most general practitioners without direct 693
OF REVIEWS
AND ABSTRACTS
Edited by J. A. Salzmann, D.D.S. New York City All inquiries regarding information on reviews and abstracts should be directed to the respective authors. Articles or books for review in this department should be addressed to Dr. J. A. Salunarm, 25 Sutton Place South, New York, New York 10022.
Workshop Proceedings: Immunological Aspects of Dental Caries National Caries Program, National Institute of Dental Research, United States Public Health Service, published by Information Retrieval, Inc.. Arlington, Va.
On Jan. 8 and 9, 1976, the National Caries Program, National Institute of Dental Research (NIH), sponsored a workshop for the critical assessment of reports of in vitro and in vivo studies on the efficacy and feasibility of immunologic prevention of dental caries and for the discussion of candidate antigens as possible immunogens in a caries vaccine. The most important discovery in caries prevention has been the cariogenicity of Streptococcus mutans. This prompted the initiation of research studies involving immunization as an approach to caries prevention. Results of studies in animal models suggest that serum and/or secretory antibodies directed to S. mutans can be effective in reducing the population of S. mutans in plaques and thus reduce the incidence of dental caries. Mutan and lipoteichoic acid are two streptococcal antigens that require further exploration to determine their immunochemical and immunobiologic natures. Because mutan is an adhesive responsible for S. mutans infectivity, specific antibodies against this polymer may prevent colonization of oral surfaces. Initial immunoprophylaxis may have to be supplemented with a nonimmunologic method to reduce oral microflora.
Minor Tooth Movement in the Growing Child M. Michael Cohen, Sr., with contributions
by John I?. Orr, Jr., and Gerard Borell
Philadelphia, 1977, W. B. Saunders Company. 143 pages, illustrated. Price, $15.00
This volume deals with the recognition and treatment of minor occlusal disharmonies in the primary and early mixed dentitions. Chapters are included on appliance construction, radiography, and cephalometrics as they apply in pediatric dentistry. Radiography is explained and the text is accompanied by excellent illustrations provided by the Eastman Kodak Company. Cohen includes specific detailed instructions on radiographing the teeth of children in the deciduous, mixed, and permanent dentitions. The use of pantographic radiography is explained. The part on treatment is outlined in the twenty-five pages of text devoted to this subject. Cohen states that deep overbite in the deciduous dentition should be treated. It is generally accepted, however, that the arrangement of the permanent teeth depends on growth of the jaws rather than on lack of spacing in the deciduous dentition. In the absence of patient micromandibular development, it is difficult to diagnose inadequate arch length in the deciduous dentition period. Valuable information is provided on the handling of overretained deciduous incisors, which is little understood at present among most general practitioners without direct 693