4388166 Electrochemical measuring apparatus provided with an enzyme electrode

4388166 Electrochemical measuring apparatus provided with an enzyme electrode

PATENT ABSTRACTS may also include beta lactamase enzyme detection utilizing the reaction of the same reagent system carrying the specimen with a peni...

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PATENT ABSTRACTS

may also include beta lactamase enzyme detection utilizing the reaction of the same reagent system carrying the specimen with a penicillin substrate.

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Synthetic substrates are provided which may be represented as A-D. The A moiety thereof includes an amino acid, polypeptide, or derivative thereof. The D moiety thereof includes 7-amino coumarin derivatives having an electron withdrawing substituent group at the 3 position carbon or fund between the 3 and 4 position carbons.

4389485 URICASE PRODUCTION METHOD Robert Olivieri, Eugeni Fascetti, Pierluig Ciuffolotti, Ludwig Degen, Mentana, Italy assigned to E N I Ente Nazionale Idrocarburi it has been found that highly active uricasc can be produced by fermentation from the microorganism Micrococcus roseus NRRL B 12196. The optimum activity of this microorganism is close to the pH values of the physiological liquors. The uricase so produced can be exploited in the clinical diagnostics for determining uric acid.

4388166

ELECTROCHEMICAL MEASURING APPARATUS PROVIDED WITH AN ENZYME ELECTRODE Shuichi Suzuki, Masuo Aizawa, Masao Koyama, Yuichi Sato, Junji Koczuka, Tokyo, Japan assigned to Tokyo Shibaura Denki Kabushiki Kaisha

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4388233 SYNTHETIC SUBSTRATES ENZYME ANALYSIS

FOR

Eugene R Bissell, Alexander Mitchell, Karen W Pearson, Robert E Smith assigned to The Regents of the University of California

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An electrochemical measuring apparatus which essemtially comprises an asymmetric semipermeable membrane mounted on an immobilized enzyme membrane of an enzyme electrode, said ssymmetric semipermeable membrane being essentially formed of a thin semipermeable layer exposed to the outside for contact with a liquid to be measured and an inner adjacent thick porous layers, and can measure an organic ingredient such as glucose contained in blood or serum with high sensitivity in a short time and moreover has a prominent durability.