BOOKS RECEIVED FOR REVIEW Biosynthesis of Terpenes and Sterols. Edited for Ciba by G. E. '~r. "\IVolstenholn1e and Maeve O'Connor. 811 pages, 102 illustrations. Boston, 1959, Little, Brown & Company. $8.75. The Differential Diagnosis of Abdominal Pain. By Sherman l\1. MellinkofL 443 pages, 29 figures. New York, 1959, McGraw-Hill Book Company, Inc. $9.00. A Doctor Discusses Menopause. By Lombard Kelly. 90 pages, 12 figures. Chicago, 195\J, Budlong Press. $1.50. Gynecology and Gynecologic Nursing. By Norman F. Miller ami Hazel A very. Fourth edition. 501 pages, 249 diagrammatic drawings. Philadelphia, 1959, W. B. Saunders Company. $5.00. Handbook of Obstetrics and Gynaecology for Nurses. By Douglas G. Wilson Clyne. 204 pages, 53 figures. Baltimore, 1958, Williams & Wilkins Company. $4.00. Over de Musculatuur van de Pars Intramuralis Tubae Falloppii en Haar Functionele Betekenis (On the Musculature of the Intramural Part of the Fallopian Tube antl Its Functional Significance). By L. C. L. M. Vasen. l11 pages, 29 figures, Groningen, 1959, Dijkstra's Drukkerij, N. V. A Primer on Common Functional Disorders. By Jack W. Fleming. 174 pages, 8 tables. Boston, 1958, Little, Brown & Company. $5.00. Protection in Diagnostic Radiology. By B. P. Sonnenblick. 346 pages, 52 tables, 93 figures. New Brunswick, 1959, Rutgers University Press. $7.50. Longitudinal Studies of Child Personality. By Alan A. Stone and Gloria Cochrane Onque. 314 pages. Cambridge, 1959, Harvard University Press. $5.00.
SELECTED ABSTRACTS American Journal of Medical Sciences Vol. 236, November, 1958. *Dinon, L. R., Kim, Y. S., and Vander Veer, J. B.: Clinical Experience ''Tith Ch!orothiazide (Diuril), With Particular Emphasis on Untoward Responses: A Report of 121 Cases Studied Over a 15 Month Period, p. 533. Dinon, Kim, and Vander Veer:
Clinical Experience With Chlorothiazide (Diuril), p. 533.
Good to excellent results were obtained in 67 per cent of the patients who required diuretic therapy; only 3 of the 9 patients with hepatic cirrhosis reacted as favorably. Hazards of continuous therapy include the low salt syndrome, hypochloremic alkalosis, and hypokalemia. Excessive hypotensive effects may occur when chlorothiazide is used along with ganglionic blocking agents. One nearly fatal drug reaction was seen and another patient showed blood and bone marrow changes suggestive of drug toxicity. It is suggested that the lowest effective daily and weekly dose schedules be followed, with periodic short rest periods. Potassium supplements are useful. In patients on digitalis or antihypertensive drugs, careful clinical and laboratory (electrolytes) observations should be made. LEON C. CHESLEY
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