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Multiple epiphyseal dysplasia
Volume 70 Number 3, part 2
Clinical entities
505
40. MULTIPLE EPIPHYSEAL DYSPLASIA (Dysplasia epiphysalis multiplex)
31/2 years Height age: 1-~2 years
57912 years Height age: 3 s/12 years
Small stature. Variable; apparently postnatal onset, usually in childhood Clinical. Short extremities with or without waddling gait; joint limitation with discomfort in hips, knees, and ankles Roentgenograms. Epiphyses: late irregular ossification with hypoplasia and flattening; short femoral neck; with or without short metacarpals and phalanges, metaphyseal flaring, and flattening of vertebrae with reduced intervertebral space Etiology. Autosomal dominant Comment. Early osteoarthritic changes are a problem. Radiologic improvement tends to occur in later childhood REFERENCES Rubin, P.: Dynamic classification of bone dysplasias, Chicago, 1964, Year Book Medical Publishers, Inc., p. 146. Lamy, M., and Maroteaux, P.: Les chondrodystrophies gfinotypiques, Paris, 1960, L'Expansion Scientifique Fran~aise, p. 53.
Clinical entities
505
40. MULTIPLE EPIPHYSEAL DYSPLASIA (Dysplasia epiphysalis multiplex)
31/2 years Height age: 1-~2 years
57912 years Height age: 3 s/12 years
Small stature. Variable; apparently postnatal onset, usually in childhood Clinical. Short extremities with or without waddling gait; joint limitation with discomfort in hips, knees, and ankles Roentgenograms. Epiphyses: late irregular ossification with hypoplasia and flattening; short femoral neck; with or without short metacarpals and phalanges, metaphyseal flaring, and flattening of vertebrae with reduced intervertebral space Etiology. Autosomal dominant Comment. Early osteoarthritic changes are a problem. Radiologic improvement tends to occur in later childhood REFERENCES Rubin, P.: Dynamic classification of bone dysplasias, Chicago, 1964, Year Book Medical Publishers, Inc., p. 146. Lamy, M., and Maroteaux, P.: Les chondrodystrophies gfinotypiques, Paris, 1960, L'Expansion Scientifique Fran~aise, p. 53.