Papers on combinatorial chemistry or solid-phase synthesis from other journals - March 1999

Papers on combinatorial chemistry or solid-phase synthesis from other journals March 1999 Discovery of peptide - zirconium complexes that mediate phosphate hydrolysis by batch screening of a combinatorial undecapeptide library. Berkessel, A.; Herault, D.A. Angew. Chem., Int. Ed. (1999), 38(1/2), 102-105. A surprising solid-phase effect: development of a recyclable "traceless" linker system for reactions on solid support. Brase, S.; Enders, D.; Kobberling, J.; Avemaria, F. Angew. Chem., Int. Ed. (1999), 37(24), 3413-3415. Strategies for the dynamic integration of combinatorial synthesis and screening. Ganesan, A. Angew. Chem., Int. Ed. (1998), 37(20), 2828-2831. Determination of Substrate Specificity for Peptide Deformylase through the Screening of a Combinatorial Peptide Library. Hu, Y-J.; Wei, Y.; Zhou, Y.; Ravi R.P.T.; Pei, D. Biochemistry (1999), 38(2), 643-650. Encoded chemical synthesis coupled to screening: "Pot Assay". Parandoosh, Z.; Knowles, S.K.; Xiao, X-Y.; Zhao, C.; David, G.S.; Nova, M.P. Comb. Chem. High Throughput Screening (1998), 1(3), 135-142. A combinatorial approach to new DNA minor groove binders. Behrens, C.; Nielsen, P.E. Comb. Chem. High Throughput Screening (1998), 1(3), 127-134. Combinatorial libraries: studies in molecular recognition. Nestler, H.P.; Liu, R. Comb. Chem. High Throughput Screening (1998), 1(3), 113-126. Ratio encoding combinatorial libraries with stable isotopes and their utility in pharmaceutical research. Wagner, D.S.; Markworth, C.J.; Wagner, C.D.; Schoenen, F.J.; Rewerts, C.E.; Kay, B.K.; Geysen, H.M. Comb. Chem. High Throughput Screening (1998), 1(3), 143-153. Ring-closing metathesis on solid support. Elaboration of a cyclization/cleavage strategy towards unsaturated α-ester-substituted N-heterocycles. Veerman, J.J.N.; Van Maarseveen, J.H.; Visser, G.M.; Kruse, C.G.; Schoemaker, H.E.; Hiemstra, H.; Rutjes, F.P.J.T. Eur. J. Org. Chem. (1998), (11), 2583-2589. Synthesis of combinatorial libraries of vinylogous sulfonamido peptides (vs-peptides). Gennari, C.; Longari, C.; Ressel, S.; Salom, B.; Piarulli, U.; Ceccarelli, S.; Mielgo, A. Eur. J. Org. Chem. (1998), (11), 2437-2449. Cycle Polyamide Motif for Recognition of the Minor Groove of DNA. Herman, D.M.; Turner, J.M.; Baird, E.E.; Dervan, P.B. J. Am. Chem. Soc. (1999), 121(6), 1121-1129.

Asymmetric synthesis of 3-phenyl-2,3-methanophenylalanine developed by panning catalysts in a library format. Moye-Sherman, D.; Welch, M.B.; Reibenspies, J.; Burgess, K. JCS Chem. Commun. (1998), (21), 2377-2378. Combinatorial 'library on bead' approach to polymeric materials with vastly enhanced chiral recognition. Murer, P.; Lewandowski, K.; Svec, F.; Frechet, J.M.J. JCS Chem. Commun. (1998), (23), 2559-2560. Impurity annihilation; a strategy for solution phase combinatorial chemistry with minimal purification. Barrett, A.G.M.; Smith, M.L.; Zecri, F.J. JCS Chem. Commun. (1998), (21), 2317-2318. Polymer backbone disassembly: polymerizable templates and vanishing supports in high loading parallel synthesis. Ball, C.P.; Barrett, A.G.M.; Poitout, L.F.; Smith, M.L.; Thorn, Z.E. JCS Chem. Commun. (1998), (22), 2453-2454. The first solid-phase synthesis of oligothiophenes. Malenfant, P.R.L.; Frechet, J.M.J. JCS Chem. Commun. (1998), (23), 2657-2658. IcePick: A Flexible Surface-Based System for Molecular Diversity. Mount, J.; Ruppert, J.; Welch, W.; Jain, A.N. J. Med. Chem. (1999), 42(1), 60-66. Metallopeptidase Inhibitors of Tetanus Toxin: A Combinatorial Approach. Martin, L.; Cornille, F.; Turcaud, S.; Meudal, H.; Roques, B.P.; Fournie-Zaluski, M-C. J. Med. Chem. (1999), 42(3), 515-525. All-D peptides recognized by an anti-carbohydrate antibody identified from a positional scanning library. Pinilla, C.; Appel, J.R.; Campbell, G.D.; Buencamino, J.; Benkirane, N.; Muller, S.; Greenspan, N.S. J. Mol. Biol. (1998), 283(5), 1013-1025. Solid-phase synthesis of peptidyl trifluoromethyl ketones. Poupart, M-A.; Fazal, G.; Goulet, S.; Mar, L.T. J. Org. Chem. (1999), 64(4), 1356-1361. Solid-Phase Synthesis of Tyrosine Peptide Aldehydes. Analogs of (S)-MAPI. Page, P.; Bradley, M.; Walters, I.; Teague, S. J. Org. Chem. (1999), 64(3), 794-799. Parallel synthesis of 1,2,3-thiadiazoles employing a "Catch and Release" strategy. Hu, Y.; Baudart, S.; Porco, J.A., Jr. J. Org. Chem. (1999), 64(3), 1049-1051. Screening an Inverted Peptide Library in Water with a Guanidinium-Based Tweezer Receptor. Davies, M.; Bonnat, M.; Guillier, F.; Kilburn, J.D.; Bradley, M. J. Org. Chem. (1998), 63(24), 8696-8703. Selenium-Linking Strategy for Traceless Solid-Phase Synthesis: Direct Loading, Aliphatic C-H Bond Formation upon Cleavage and Reaction Monitoring by Gradient MAS NMR

Spectroscopy. Ruhland, T.; Andersen, K.; Pedersen, H. J. Org. Chem. (1998), 63(25), 9204-9211. Synthesis of hydantoins via N,N'-ureas derived from polymer-bound amino acids. Bauser, M.; Winter, M.; Valenti, C.A.; Wiesmuller, K-H.; Jung, G. Mol. Diversity (1998), 3(4), 257-260. An artificial cell-cycle inhibitor isolated from a combinatorial library. Cohen, B.A.; Colas, P.; Brent, R. Proc. Natl. Acad. Sci. USA. (1998), 95(24), 14272-14277. Formation of 4-alkoxybenzylidene acetals on solid support and generation of functional diversity with carbohydrate scaffolds. Hanessian, S.; Huynh, H.K. Synlett (1999), (1), 102-104. Solid-phase synthesis of 3H-quinazolin-4-ones based on an aza Wittig-mediated annulation strategy. Villagordo, J.M.; Obrecht, D.; Chucholowsky, A. Synlett (1998), (12), 1405-1407.