Questions linked to Vonberg R-P, Gastmeier P. Nosocomial aspergillosis in outbreak settings. J Hosp Infect 2006;62:246–254.

Questions linked to Vonberg R-P, Gastmeier P. Nosocomial aspergillosis in outbreak settings. J Hosp Infect 2006;62:246–254.

Journal of Hospital Infection (2006) 64, 83e84 www.elsevierhealth.com/journals/jhin Continuing Professional Development and the Journal of Hospital ...

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Journal of Hospital Infection (2006) 64, 83e84

www.elsevierhealth.com/journals/jhin

Continuing Professional Development and the Journal of Hospital Infection Questions linked to Vonberg R-P, Gastmeier P. Nosocomial aspergillosis in outbreak settings. J Hosp Infect 2006;62:246e254. Available online 5 July 2006

(a) Lung transplant patients are more likely to become infected than patients undergoing renal or liver transplantation. (b) Most nosocomial aspergillus infections are observed on intensive care units. (c) Mortality in patients suffering from haematological malignancies is significantly higher compared with patients without any known severe immunodeficiency. (d) Mortality in patients suffering from haematological malignancies is greater than 90%. (e) Only infection by A. fumigatus is associated with significant mortality.

1. Which of the following statements about the epidemiology of aspergillosis in outbreak settings is incorrect? (a) Air is the major route of transmission of aspergillus spores. (b) The lower respiratory tract is the most common primary site of infection. (c) In nosocomial infections, the predominant species are Aspergillus fumigatus and Aspergillus flavus. (d) Malfunctioning air supply systems are the main reason for nosocomial aspergillosis. (e) There is no defined maximal concentration of airborne aspergillus spores that may be tolerated in high-risk patient care.

3. Which of the following statements about surveillance of nosocomial aspergillosis is incorrect?

2. Which of the following statements about the infection and mortality of nosocomial aspergilllosis in nosocomial outbreaks is correct?

(a) Surveillance of infections in patients that are at increased risk for invasive aspergillosis should be performed.

Summarizing the instructions from the Royal College of Pathologists: (1) One CPD point is allowed for each question and answer set (up to five questions and answers). (2) Answers must be recorded referenced back to the questions and recorded in the CPD portfolio. (3) It is essential that participants include the completed response form showing both questions and answers in their portfolio as these may be subject to audit by RCPath. For further information about the Royal College of Pathologists’ CPD scheme and credit allocation, please contact: Professional Standards Unit, CPD Section, Royal College of Pathologists, 2 Carlton House Terrace, London, SW1Y 5AF, UK. E-mail: [email protected] or visit http://www.rcpath.org 0195-6701/$ - see front matter ª 2006 The Hospital Infection Society. Published by Elsevier Ltd. All rights reserved. doi:10.1016/j.jhin.2006.04.006

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Continuing Professional Development and the Journal of Hospital Infection (b) Standardized definitions for invasive aspergillosis in immunocompromised patients should be used. (c) In the case of an outbreak, gravity sedimentation methods (e.g. open Petri dish) should be used rather than volumetric methods to determine the concentration of airborne spores.

(d) When using volumetric methods (e.g. Anderson sampler), sampling should be conducted using large volumes (>1.000 L). (e) Genotyping of isolates may be performed to distinguish between the outbreak strain and unrelated strains.