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Subject index for volume 2
MOLECULAR
AND CELLULAR
NEUROSCIENCES
2,528~534
(1991)
Subject Index for Volume 2 A
FASEB Summer Research Conferences: 1991 Schedule and Organizers, 86 First International Symposium on Neurobiology and Neuroendocrinology of Aging, Bregenz, Austria, July 1992, 274,446 George B. Koelle Symposium on Cholinergic System, Philadelphia, Pennsylvania, October 1991, 87 International Congress on Growth Hormone and Somatomedins during Lifespan, Satellite of N.I.C.E. 1992, Milan, Italy, September 1992,447 Keystone Symposium on Molecular and Cellular Biology, 1992, 361 Molecular Aspects of Autoimmunity (International Meeting with Emphasis on Dysthyroid Ophthalmology, Thyroid Autoimmunity, and Type I Diabetes), Mainz, Germany, August 1992, 275 Ninth International Congress of Endocrinology, Nice, France, AugustSeptember 1992,362 Satellite Symposium of IXth International Congress of Endocrinology (Melatonin and the Pineal Gland: From Basic Science to Clinical Application), Paris, France, September 1992, 362 2nd International Workshop on Insulin-Like Growth Factor Binding Proteins, Opio, France, August 1992,361 Seventh International Symposium on Facial Nerve, Cologne, Germany, June 1992,274 Summer Neuropeptide Conference: Tentative Program, Cape Cod, Massachusetts, August 1992, 86 12th International Congress on Animal Reproduction, The Hague, The Netherlands, August 1992,447 XXIII Congress of International Society of Psychoneurcendocrinology (ISPNE), Madison, Wisconsin, August 1992, 275 Antibodies monoclonal, against dopamine-releasing protein, induction of arrested fetal development, reduced brain catecholamines, and increased adrenal weight (rat), 410 APl complex in PC12 cells, protein composition, variation after induction by nerve growth factor and TPA, 253 Arcuate nucleus pro-opiomelanocortin gene expression, inhibition by activation of GABA*-benzodiazepine receptor complex (rat), 440 tachykinin expression during continuous estrogen replacement: reduction of neurokinin B (rat), 299 ATPase Na,K-, (Y and @ subunit isoforms, mRNA expression in cochlea (rat), 179 Atria1 natriuretic peptide and endothelin, review: interactions in central nervous system and periphery, 189 Atria1 natriuretic peptide receptors guanylate cyclase-coupled, evidence for presence on neurohypophysial pituicytes (rat), 363 Axons goldfish Mauthner cells and rat dorsal and ventral roots, local protein synthesis in vitro, 384 growing, in cultured hippocampal neurons, association with microtubule-associated protein MAPlB (rat), 39
Acetylcholine receptors muscarinic m2 and m3, mRNAs, different responses to microtubule-affecting drugs (rat), 315 m3, mRNA levels, maintenance, role of microtubule structure (rat), 123 nicotinic, expression by TE671/RD cells, effects of second messenger modulation and sodium butyrate treatment (human), 52 Acetylcholinesterase activity and localization in denervated ductus deferens (guinea pig), 202 ACTH, see Adrenocorticotropin Activin production and action, molecular basis, review, 449 Adrenalectomy time- and region-dependent effect on neuropeptide gene expression in hippocampus and striatum (rat), 485 transforming growth factor 81 mRNA in brain of affected rats, reduction by corticosterone, 221 Adrenal gland increased weight in neonatal rata injected with monoclonal antibodies against dopamine-releasing protein, 410 Adrenal medulla chromaffin vesicles, isolation of tetradecapeptide with strong homology to predicted sequence of rat secretogranin III (bovine), 511 cultured cells, proenkephalin gene expression, regulation by angiotensin (bovine), 213 nuclear proteins, cholinergic agonist-induced binding to rat preproenkephalin promoter, 517 Adrenergic receptors a and 8, mRNAs, localization in brain and peripheral tissues with in situ hybridization (rat), 344 Adrenocorticotropin secretion by corticotropes in mixed and enriched cultures, enhancement by epidermal growth factor (rat), 235 y-Aminobutyric acid receptors GABAA -benzodiazepine receptor complex, activation, inhibition of proopiomelanocortin gene expression in arcuate nucleus (rat), 440 y2 subunit, alternatively spliced forms, localization and functional expression (murine brain, Xenopus oocytes), 338 Amygdala kindling, and electroconvulsive seizures, effects on expression of corticotropin-releasing hormone in brain (rat), 103 Androgen receptors encoding gene, expression in central nervous system: evidence for two mRNA transcripts (rat), 117 Angiotensin-converting enzyme, see Dipeptidyl carboxypeptidase I Announcements Conference on Neurohypophysis: A Window on Brain Function, Hanover, New Hampshire, July 1992,446 8th International Conference on Second Messengers and Phosphoproteins: Biology and Medicine of Signal Transduction, Glasgow, Scotland, August 1992,274 Eleventh Annual Lexington Hormone Research Symposium, Lexington, Kentucky, May 1992,361 1044-7431/91$3.00 Copyright 0 1991 by Academic Press, Inc. All rights of reproduction in any form reserved.
I3 Bacteria Escherichia factor, 528
coli, 369
expression
of recombinant
rat
ciliary
neurotrophic
SUBJECT Basal ganglia detection of high levels of Goif proteins (rat), 66 Behavior sexual, see Sexual behavior Benzodiazepine receptors -GABA, receptor complex, activation, inhibition of pro-opiomelanocortin gene expression in arcuate nucleus (rat), 440 Bradykinin modulation of electrophysiology of cultured sensory neurons through pertussis toxin-insensitive G protein (rat), 21 Brain, see also specific regions (Y- and &adrenergic receptor mRNA, localization with in situ hybridization (rat), 344 catecholamine levels, effects of monoclonal antibodies against dopamine-releasing protein (neonatal rat), 410 expression of angiotensin converting enzyme gene, enhancement by converting enzyme inhibitors (rat), 13 corticotropin-releasing hormone gene demonstration by in situ hybridization analysis (mouse), 266 effects of amygdala kindling and electroconvulsive seizures (rat), 103 functional foreign gene after in uivo transfer via herpes simplex virus type 1 defective viral vector (adult rat), 320 glucose transporter gene, effects of chronic insulin-induced hypoglycemia, fasting, and diabetes (rat), 244 pro-opiomelanocortin and gonadotropin-releasing hormone genes, pubertal changes (male monkey), 31 GABA* receptor y2 subunit, alternatively spliced forms, localization (mouse), 338 melatonin binding sites, distribution (goldfish), 78 transforming growth factor pl mRNA levels, decrease after glucocorticoid treatment in adrenalectomized rats, 221 Brain stem tryptophan hydroxylase gene expression, post-transcriptional control (rat), 71 Butyrylcholine esterase, see Cholinesterase
C Calcium channels in cultured sensory neurons, modulation by bradykinin through pertussis toxin-insensitive G protein (rat), 21 Captopril enhancement of neuronal angiotensin converting enzyme gene expression (rat), 13 Carbachol and sodium fluoride, differential effects on phosphoinositide metabolism in PC12 cells, 377 Castration effects on pretranslational expression of preoptic regulatory factor 1 mRNAs in brain and liver (rat), 395 Catecholamines cerebral, in neonatal rats, effects of monoclonal antibodies against dopamine-releasing protein, 410 Cell lines medulloblastoma, TE671/RD, nicotinic acetylcholine receptor expression, effects of second messenger modulation and sodium butyrate treatment (human), 52 neural, RT4, differential expression of homeobox genes (rat), 172 Central nervous system, see also speci& regions androgen receptor gene expression: evidence for two mRNA transcripts (rat), 117 fl-endorphin administration, regulation of insulin-induced ornithine decarboxylase expression in liver (neonatal rat), 1 Cerebellum granule cells, see Granule cells
529
INDEX
Cerebral cortex preoptic regulatory factor 1 mRNA levels, effects of hypophysectomy and castration (rat), 395 Cholecystokinin gene expression in hippocampus and striatum, time- and regiondependent effect of adrenalectomy (rat), 465 Choline acetyltransferase activity and localization in denervated ductus deferens (guinea pig), 202 Cholinesterase activity and localization in denervated ductus deferens (guinea pig), 202 Choroid plexus vitamin D receptors, identification (hamster, mouse, rat), 145 Ciliary neurotrophic factor recombinant, expression in Escherichia coli and synergy with basic fibroblast growth factor (rat), 369 Clorgyline reduction of preprotachykinin mRNA in adult medullary raphe nuclei (rat), 139 Cochlea expression of mRNAs encoding Na,K-ATPase (Y and fi subunit isoforms (rat), 179 Colchicine and fi-lumicolchicine and taxol, differential responses of m2- and m3muscarinic acetylcholine receptor mRNAs (rat), 315 Converting enzyme inhibitors enhancement of neuronal angiotensin converting enzyme gene expression (rat), 13 Corpus striatum and hippocampus, neuropeptide gene expression, time- and regiondependent effect of adrenalectomy (rat), 465 inducible preproenkephalin DNA-binding proteins, identification (rat), 427 Corticosterone induced decrease in transforming growth factor 81 mRNA in brain of adrenalectomized rats, 221 Corticotropes ACTH secretion and pro-opiomelanocortin mRNA expression in mixed and enriched cultures, enhancement by EGF (rat), 235 Corticotropin-releasing hormone encoding gene, nucleotide sequence and expression in brain (mouse), 266 expression in brain, effects of amygdala kindling and electroconvulsive seizures (rat), 103
D Degeneration and regeneration, nerve terminals in pituitary pars intermedia after 6-hydroxydopamine treatment (rat), 418 Denervation ductus deferens, effect on cholmesterases and choline acetyltransferase (guinea pig), 202 Desensitization D1 dopamine receptor: role of CAMP-dependent and receptor-specific protein kinases (human), 464 Development associated expression of class II j3-tubulin mRNA in hypothalamus, sex-related difference (rat), 130 fetal, effects of monoclonal antibodies against dopamine-releasing protein (rat), 410 pubertal changes in pro-opiomelanocortin and gonadotropin-releasing hormone gene expression in brain (male monkey), 31 Diabetes effect on glucose transporter gene expression in brain (rat), 244
530
SUBJECT
Dibutyryl cyclic AMP induction of differentiation and reduction of opioid receptor binding activity in N4TGl neuroblastoma cells, 284 and/or PMA, and sodium butyrate treatment, effects on nicotinic acetylcholine receptor expression by TE671/RD cells (human), 52 Differentiation N4TGl neuroblastoma cells, induction by insulin-like growth factor I and dibutyryl CAMP, 284 sexual, see Sexual differentiation Dipeptidyl carboxypeptidase I neuronal, gene expression, enhancement by converting enzyme inhibitors (rat), 13 DNA praproenkephalin, inducible striatal proteins binding to, identification (rat), 427 Dopamine receptors Di, desensitization: role of CAMP-dependent and receptor-specific protein kinases (human), 464 Dorsal root and ventral root, local axonal protein synthesis in vitro, comparison with goldfish Mauthner cell axons (rat), 384 Ductus deferens denervated, cholinesterases and choline acetyltransferase in, activity and localization (guinea pig), 202 E EGF, see Epidermal growth factor fl-Endorphin central nervous system, regulation of insulin-induced ornithine decarboxylase expression in liver (neonatal rat), 1 Endothelin and atria1 natriuretic peptide, review: interactions in central nervous system and periphery, 189 Ependyma vitamin D receptors, identification (hamster, mouse, rat), 145 Epidermal growth factor enhancement of ACTH secretion and pro-opiomelanocortin mRNA expression by corticotropes in mixed and enriched cultures (rat), 235 Estrogen continuous replacement, effect on tachykinin expression in arcuate nucleus: reduction of neurokinin B (rat), 299 Estrous cycle preprosomatostatin mRNA levels in hypothalamic periventricular nucleus during, variations (rat), 294 F Fasting effect on glucose transporter gene expression in brain (rat), 244 Fetus development, arrest by monoclonal antibodies against dopamine-releasing protein (rat), 410 Fihroblast growth factor basic, and recombinant rat ciliary neurotrophic factor expressed in Escherichia coli, synergetic effects on cultured neurons, 369 effect on N4TGl neuroblastoma cell differentiation and opioid receptor binding activity, 284 Fibroblasts L cell line with CAMP-responsive reporter construct, in screening ligands binding to cloned G,- or Gi-coupled receptors (mouse), 331 renal and L929 cell line, nerve growth factor gene expression: role of downstream AP-1 element in basal and modulated transcription (mouse), 157
INDEX Follicle-stimulating hormone cy and /3 subunits, steady-state mRNA levels in superfused pituitary cell cultures, enhancement by pulsatile GnRH stimulation (rat), 277 FSH, see Follicle-stimulating hormone G GABA receptors, see y-Aminobutyric acid receptors fl-Galactosidase encoding gene, foreign, expression in adult brain after in uiuo transfer via herpes simplex virus type 1 defective viral vector (rat), 320 Ganglion cells retinal, GAP-43 mRNA levels during regeneration, post-transcriptional regulation (goldfish), 402 Genes androgen receptor, expression in central nervous system: evidence for two mRNA transcripts (rat), 117 angiotensin-converting enzyme, neuronal expression, enhancement by converting enzyme inhibitors (rat), 13 brain-derived neurotrophic factor, expression in brain tumors (human), 168 corticotropin-releasing hormone, nucleotide sequence and expression in brain (mouse), 266 glucose transporter, expression in brain, effects of chronic insulininduced hypoglycemia, fasting, and diabetes (rat), 244 homeobox, differential expression in neural cell lines (rat), 172 lacZ, foreign, expression in adult brain after in uiuo transfer via herpes simplex virus type 1 defective viral vector (rat), 320 nerve growth factor, expression in brain tumors (human), 168 fibroblasts: role of downstream AP-1 element in basal and modulated transcription (mouse), 157 neuropeptide, expression in hippocampus and striatum, time- and region-dependent effect of adrenalectomy (rat), 485 oncogenes v-src, c-Ha-ras, and v-mos, retroviral transfer, in establishment of Schwann cell lines (mouse, rat), 6 oxytocin, promoter, identification of &-acting regulatory elements (human), 501 potassium channel, families in mammals, review: molecular basis of K+ channel diversity, 89 preproenkephalin, promoter, cholinergic agonist-induced binding to adrenomedullary nuclear proteins (rat), 517 preprosecretogranin III, encoded internal sequence, strong homology in tetradecapeptide isolated from bovine adrenal medulla chromaffin vesicles (rat), 511 proenkephalin expression in adrenal medullary cells, regulation by angiotensin (bovine), 213 and prodynorphin, expression in anteroventral periventricular nucleus, role of sexual differentiation and hormonal regulation (rat), 473 pro-opiomelanocortin expression in arcuate nucleus, inhibition by activation of GABAAbenzodiazepine receptor complex (rat), 440 and gonadotropin-releasing hormone, expression in brain, pubertal changes (male monkey), 31 tryptophan hydroxylase, expression in brain stem and pineal gland, post-transcriptional control (rat), 71 tyrosine hydroxylase, encoded products in neocortex, neuronal localization (human), 228 Gene transfer in adult brain in uiuo via herpes simplex virus type 1 defective viral vector, subsequent expression of functional foreign protein (rat), 320 Glucocorticoids inhibitory control of transforming growth factor fll-regulated actions in brain (rat), 221
SUBJECT Glucose transporters gene expression in brain, effects of chronic insulin-induced bypoglycemia, fasting, and diabetes (rat), 244 GLUT1 and GLUT3, expression in cultured cerebellar neurons: evidence for neuron-specific GLUT3 expression (rat), 351 GnRH, see Gonadotropin-releasing hormone Gonadotropin-releasing hormone gene expression in brain, pubertal changes (male monkey), 31 pulsatile stimulation, enhancement of steady-state mRNA levels for FSHj3, LH& and (Y subunits in superfused pituitary cell cultures (rat), 277 G protein-coupled receptors G.- or G,-coupled, cloned, ligands binding to, screening (murine L cells), 331 G proteins G,,r, detection in basal ganglia in high levels (rat), 66 pertussis toxin-insensitive, role in bradykinin modulation of physiology of cultured sensory neurons (rat), 21 Granule cells cerebellar cultured, expression of glucose transporters GLUT1 and GLUTB: evidence for neuron-specific GLUT3 expression (rat), 351 muscarinic acetylcholine receptor mRNAs m2 and m3, different responses to microtubule-affecting drugs (rat), 315 m3, maintenance, role of microtubule structure (rat), 123 Guanylate cyclase coupled atria1 natriuretic peptide receptors, evidence for presence on neurohypophysial pituicytes (rat), 363
H Herpes simplex virus type 1 defective vector, application to transfer of foreign gene to adult rat brain in vivo, 320 Hippocampus [3H]inositol phosphate formation in slices, luteinizing hormonereleasing hormone-induced facilitation (rat), 208 and striatum, neuropeptide gene expression, time- and region-dependent effect of adrenalectomy (rat), 485 Homeobox containing genes, differential expression in neural cell lines (rat), 172 Hybridization in situ in analysis of interleukin-10 mRNA induction by methamphetamine in hypothalamus (rat), 259 in localization of (Y- and @-adrenergic receptor mRNA in brain and peripheral tissues (rat), 344 6-Hydroxydopamine induced degeneration of nerve terminals in pituitary pars intermedia, subsequent regeneration (rat), 418 Hypoglycemia insulin-induced, chronic, effect on glucose transporter gene expression in brain (rat), 244 Hypophysectomy effects on pretranslational expression of preoptic regulatory factor 1 mRNAs in brain, liver, and testis (rat), 395 Hypothalamus arcuate nucleus, see Arcuate nucleus developmental expression of class II fl-tubulin mRNA, sex-related difference (rat), 130 interleukin-1@ mRNA induction by metbamphetamine, in situ hybridization analysis (rat), 259 periventricular nucleus, see Periventricular nucleus preoptic regulatory factor 1 mRNA levels, effects of hypopbysectomy and castration (rat), 395 ventromedial, protein patterns, correlation with progesterone-dependent sexual behavior (adult female rat), 491
531
INDEX I
Inhibin production and action, molecular basis, review, 449 Inositol phosphate ‘H-labeled, formation in hippocampal slices, luteinizing hormonereleasing hormone-induced facilitation (rat), 208 Insulin effact on N4TGl neuroblastoma cell differentiation and opioid receptor binding activity, 284 induced hypoglycemia, effect on glucose transporter gene expression in brain (rat), 244 induced ornithine decarboxylase expression in liver, regulation by central nervous system j%endorphin (neonatal rat), 1 Insulin-like growth factor I induction of differentiation and reduction of opioid receptor binding activity in N4TGl neuroblastoma cells, 284 Interleukin-10 mRNA, induction by methamphetamine in hypothalamus, in situ hybridization analysis (rat), 259 Ion channels calcium, see Calcium channels nonselective, in cultured sensory neurons, modulation by bradykinin through pertussis toxin-insensitive G protein (rat), 21 potassium, see Potassium channels
K Kindling amygdala, and electroconvulsive seizures, effects on expression corticotropin-releasing hormone in brain (rat), 103
of
LH, see Luteinizing hormone Ligand screening assay ligands binding to cloned G,- or Gi-coupled receptors (murine L cells), 331 Lisinopril enhancement of neuronal angiotensin converting enzyme gene expression (rat), 13 Liver insulin-induced ornithine decarboxylase expression, regulation by central nervous system &endorphin (neonatal rat), 1 preoptic regulatory factor 1 mRNA levels, effects of hypophysectomy and castration (rat), 395 &Lumicolchicine and colchicine and taxol, differential responses of m2- and m3-muscarinic acetylcholine receptor mRNAs (rat), 315 Luteinizing hormone a! and fl subunits, steady-state mRNA levels in superfused pituitary cell cultures, enhancement by pulsatile GnRH stimulation (rat), 277 Luteinizing hormone-releasing hormone facilitation of [3H]inositol phosphate formation in hippocampal slices (rat), 208
M Mauthner cells goldfish, local axonal protein synthesis in vitro, comparison with rat dorsal and ventral root axons, 384 Medullary raphe nuclei preprotachykinin mRNA levels, reduction by zimelidine and clorgyline (rat), 139 Melatonin binding sites in brain and pituitary, distribution (goldfish), 78
532
SUBJECT
Methamphetamine induction of interleukin-10 mRNA in hypothalamus, in situ hybridization analysis (rat), 259 Microtubules affecting drugs, differential responses of m2- and m3-muscarinic acetylcholine receptor mRNAs (rat), 315 associated protein MAPlB, association with growing axons in cultured hippocampal neurons (rat), 39 structure, role in maintenance of m3-muscarinic acetylcholine receptor mRNA levels (rat), 123 Muscles smooth, denervated, cholinesterases and choline acetyltransferase in, activity and localization (guinea pig ductus deferens), 202 N
Neocortex tyrosine hydroxylase gene products, neuronal localization (human), 228 Nerve growth factor and brain-derived neurotrophic factor, gene expression in brain tumors (human), 168 gene expression: role of downstream AP-1 element in basal and modulated transcription (murine fibroblasts), 157 and TPA, induction of PC12 cells, effect on composition of APl complex, 253 Nerves optic, regeneration, associated GAP-43 mRNA levels, post-transcriptional regulation (goldfish), 402 Nerve terminals in pituitary pars intermedia, degeneration and regeneration after 6hydroxydopamine treatment (rat), 418 Neurohypophysis pituicytes, evidence for presence of guanylate cyclase-coupled receptors for atria1 natriuretic peptide (rat), 363 Neurokinin B expression in arcuate nucleus, reduction by continuous estrogen replacement (rat), 299 Neurons angiotensin converting enzyme gene expression, enhancement by converting enzyme inhibitors (rat), 13 cultured, ciliary, synergetic effects of recombinant rat ciliary neurotrophic factor expressed in Esc/rcrichio coli and basic flbroblast growth factor (chicken), 369 differentiation, GAP-43 mRNA levels during, post-transcriptional regulation (goldfish, rat), 402 hippocampal, growing axons in culture, association with microtubuleassociated protein MAPlB (rat), 39 neocortical, localization of tyrosine hydroxylase gene products (human), 228 sensory, electrophysiology in culture, modulation by bradykinin through pertussis toxin-insensitive G protein (rat), 21 Neuropeptide Y gene expression in hippocampus and striatum, time- and region-dependent effect of adrenalectomy (rat), 485 Neurotrophic factors brain-derived, and nerve growth factor, gene expression in brain tumors (human), 168 ciliary, see Ciliary neurotrophic factor Nicotine induction of binding of adrenomedullary nuclear proteins to rat preproenkephalin promoter, analysis, 517 Nuclei, see specific nuclei Nucleoproteins adrenomedullary, cholinergic agonist-induced binding to rat preproenkephalin promoter, 517 Nucleotide sequence corticotropin-releasing hormone gene (mouse), 266
INDEX 0 Oocytes
functional expression of alternatively spliced forms of GABA* receptor yz subunit (Xenopus laevis), 338 Opioid receptors binding activity in N4TGl neuroblastoma cells, reduction by insulinlike growth factor I and dibutyryl CAMP, 284 Ornithine decarboxylase insulin-induced expression in liver, regulation by central nervous system B-endorphin (neonatal rat), 1 Oxotremorine induction of binding of adrenomedullary nuclear proteins to rat preproenkephalin promoter, analysis, 517 Oxytocin gene promoter, identification of &-acting regulatory elements (human), 501
P
Periventricular nucleus anteroventral, prodynorphin and proenkephalin gene expression, role of sexual differentiation and hormonal regulation (rat), 473 preprosomatostatin mRNA levels, variations during estrous cycle (rat), 294 Phorboll2-myristate 13-acetate and/or dbcAMP, and sodium butyrate treatment, effects on nicotinic acetylcholine receptor expression by TE671/RD cells (human), 52 Phosphoinositides metabolism in PC12 cells, differential sensitivity to sodium fluoride and carbachol treatments, 377 Pineal gland tryptophan hydroxylase gene expression, post-transcriptional control (rat), 71 Pituicytes presence of guanylate cyclase-coupled receptors for atrial natriuretic peptide, evidence (rat), 363 Pituitary anterior, derived corticotropes, ACTH secretion and pro-opiomelanocortin mRNA expression in mixed and enriched cultures, enhancement by EGF (rat), 235 intermediate lobe, nerve terminals, degeneration and regeneration after 6-hydroxydopamine treatment (rat), 418 melatonin binding sites, distribution (gold&h), 78 posterior lobe, see Neurohypophysis superfused cell cultures, steady-state mRNA levels for FSHB, LHj3, and (Y subunits, enhancement by pulsatile GnRH stimulation (rat), 277 Placenta preoptic regulatory factor 1 mRNA, analysis (human), 395 PMA, see Phorbol 12-myristate 13-acetate Polyribosomes synaptoneurosomal, protein translation, triggering by K+ stimulation (rat), 305 Potassium channels gene families in mammals, review: molecular basis of K+ channel diversity, 89 Potassium ions stimulation of synaptoneurosomal polyribosomes, associated triggering of protein translation (rat), 305 Preoptic regulatory factor 1 mRNAs, pretranslational expression, direction by intrinsic and extrinsic modulators (human, rat), 395 Preprodynorphin gene expression in hippocampus and striatum, timeand regiondependent effect of adrenalectomy (rat), 485
SUBJECT Preproenkephalin gene expression in hippocampus and striatum, time- and regiondependent effect of adrenalectomy (rat), 485 gene promoter choline&c agonist-induced binding to adrenomedullary nuclear proteins (rat), 517 inducible striatal proteins binding to, identification (rat), 427 Preprotacbykinin mRNA levels in adult medullary raphe nuclei, reduction by zimelidine and clorgyline (rat), 139 Prodynorphin gene expression in anteroventral periventricular nucleus, role of sexual differentiation and hormonal regulation (rat), 473 Proenkephalin gene expression in adrenal medullary cells, regulation by angiotensin (bovine), 213 anteroventral periventricular nucleus, role of sexual differentiation and hormonal regulation (rat), 473 Progesterone dependent sexual behavior, and protein patterns in ventromedial hypothalamus, correlation (adult female rat), 491 Promoters oxytocin gene, identification of &-acting regulatory elements (human), 501 preproenkephalin gene, choline@ agonist-induced binding to adrenomedullary nuclear proteins (rat), 517 Pro-opiomelanocortin gene expression in arcuate nucleus, inhibition by activation of GABAA-benzodiazepine receptor complex (rat), 440 brain, pubertal changes (male monkey), 31 mRNA expression by corticotropes in mixed and enriched cultures, enhancement by epidermal growth factor (rat), 235 Protein kinases CAMP-dependent and receptor-specific, role in desensitization of D1 dopamine receptor (human), 464 Proteins composition in APl complex, variation after induction by nerve growth factor and TPA (PC12 cells), 253 dopamine-releasing, monoclonal antibodies, induction of arrested fetal development, reduced brain catecholamines, and increased adrenal weight (rat), 410 growth-associated, GAP-43, mRNA levels during neuronal differentiation and nerve regeneration, post-transcriptional regulation (goldfish, rat), 402 microtubule-associated, MAPlB and MAPS, distribution during differentiation of cultured hippocampal neurons, comparison (rat), 39 preproenkephalin DNA-binding, inducible, identification in striatum (rat), 427 Protein synthesis associated mRNA translation in synaptoneurosomal polyribosomes, triggering by K+ stimulation (rat), 305 local axonal, in goldfish Mauthner cell axon and rat dorsal and ventral root axons in vitro, 384 in ventromedial hypothalamus of adult female rat, correlation with progesterone-dependent sexual behavior, 491 R Raphe medullary, nuclei, preprotachykinin mRNA levels, reduction by zimelidine and clorgyline (rat), 139 Regeneration nerve terminals in pituitary pars intermedia after 6-hydroxydopamine treatment (rat), 418 retinal ganglion cells, associated GAP-43 mRNA levels, post-transcriptional regulation (goldfish), 402
533
INDEX
RNA messenger c~- and @-adrenergic receptors, localization in brain and peripheral tissues with in situ hybridization (rat), 344 androgen receptor, evidence for two forms in central nervous system (rat), 117 class II @-tubulin, developmental expression in hypothalamus, sexrelated difference (rat), 130 FSH& LH& and OL subunits, steady-state levels in superfused pituitary cell cultures, enhancement by pulsatile GnRH stimulation (rat), 277 GAP-43, levels during neuronal differentiation and nerve regeneration, post-transcriptional regulation (gold&h, rat), 402 interleukin-l/3, induction by methamphetamine in hypothalamus, in situ hybridization analysis (rat), 259 muscarinic acetylcholine receptors m2 and m3, different responses to microtubule-affecting drugs (rat), 315 m3, maintenance of levels in cerebellar granule cells, role of microtubule structure (rat), 123 Na,K-ATPase (Y and j3 subunit isoforms, expression in cochlea (rat), 179 preoptic regulatory factor 1, pretranslational expression, direction by intrinsic and extrinsic modulators (human, rat), 395 preprosomatostatin, levels in hypothalamic periventricular nucleus, variations during estrous cycle (rat), 294 preprotachykinin, levels in adult medullary raphe nuclei, reduction by zimelidine and clorgyline (rat), 139 transforming growth factor 81, reduction in brain in response to glucocorticoid treatment of adrenalectomized rats, 221 translation in synaptoneurosomal polyribosomes, triggering by K+ stimulation (rat), 305
S Schwann cells cell lines, establishment by oncogene transfer (mouse, rat), 6 Second messenger systems involved in angiotenein regulation of proenkephalin gene expression in adrenal medullary cells, analysis (bovine), 213 modulation, and sodium butyrate treatment, effects on nicotinic acetylcholine receptor expression by TE671/RD cells (human), 52 Secretogranin III predicted sequence, strong homology to tetradecapeptide isolated from bovine adrenal medulla chromaffin vesicles (rat), 511 Seizures amygdala kindled and electroconvulsive, effects on expression of corticotropin-releasing hormone in brain (rat), 103 Sex differences developmental expression of class II j3-tubulin mRNA in hypothalamus (rat), 130 Sexual behavior progesterone-dependent, and protein patterns in ventromedial hypothalamus, correlation (adult female rat), 491 Sexual differentiation and hormonal regulation, role in prodynorphin and proenkephalin gene expression in anteroventral periventricular nucleus (rat), 473 Sodium butyrate and second messenger modulation, effects on nicotinic acetylcholine receptor expression by TE671/RD cells (human), 52 Sodium fluoride and carbachol, differential effects on phosphoinositide metabolism in PC12 cells, 377 Somatostatin precursor mRNA . levels in hypothalamic nucleus, _. ~. periventricular variations during estrous cycle (rat), 294
534
SUBJECT
Steroids reproductive, and sexual differentiation, role in prodynorphin and proenkephalin gene expression in anteroventral periventricular nucleus (rat), 473 Synaptoneurosomes polyribosomes in, protein translation, triggering by K+ stimulation (rat), 305 T Tachykinins expression in arcuate nucleus during continuous estrogen replacement: reduction of neurokinin B (rat), 299 Taxol and colchicine and fi-lticolchicine, differential responses of m2- and m3-muscarinic acetylcholine receptor mRNAs (rat), 315 Testis pretranslational preoptic regulatory factor 1 mRNA levels, effects of pituitary and testicular factors (rat), 395 12-0-Tetradecanoylphorbol-13-acetate and nerve growth factor, induction of PC12 cells, effect on composition of APl complex, 253 Tetradecapeptide isolated from bovine adrenal medulla chromaffin vesicles, strong homology to predicted sequence of rat secretogranin III, 511 Tissues peripheral, (Y- and /3-adrenergic receptor mRNAs, localization with in situ hybridization (rat), 344 TPA, see 12-0-Tetradecanoylphorbol-13-acetate Transcription nerve growth factor gene, basal and modulated, role of downstream AP-1 element (murine fibroblasts), 157 Transforming growth factor 81 mRNA reduction in brain in response to glucocorticoid treatment of adrenalectomized rata, 221 Translation proteins in synaptoneurosomal polyribosomes, triggering by K+ stimulation (rat), 305 Tryptophan 5-hydroxylase, see Tryptophan 5monooxygenase Tryptophan 5-monooxygenase encoding gene, expression in brain stem and pineal gland, post-transcriptional control (rat), 71 &Tubulin class II, mRNA, developmental expression in hypothalamus, sexrelated difference (rat), 130
INDEX Tumor cells neurohlastoma, N4TG1, differentiation and opioid receptor binding activity, effects of fibroblast growth factor, insulin, insulin-like growth factor, and Bt,cAMP (mouse), 284 neurotumor, SK-M-MC, D, dopamine receptors in, desensitization: role of CAMP-dependent and receptor-specific protein kinases (human), 464 pheochromocytoma, PC12 APl complex protein composition, variation after induction by nerve growth factor and TPA (rat), 253 GAP-43 mRNA levels during differentiation, post-transcriptional regulation (rat), 402 phosphoinositide metabolism, differential sensitivity to sodium fluoride and carbachol treatments (rat), 377 Tumors brain, brain-derived neurotrophic factor and nerve growth factor gene expression (human), 168 Tyrosine hydroxylase gene products in neocortex, neuronal localization (human), 228 V Vectors defective, herpes simplex virus type 1, application to transfer of foreign gene to adult rat brain in uiuo, 320 oncogenic, application in establishment of Schwann cell lines (mouse, rat), 6 Ventral root and dorsal root, local axonal protein synthesis in vitro, comparison with goldfish Mauthner cell axons (rat), 384 Vesicles chromaffin, from bovine adrenal medulla, isolation of tetradecapeptide with strong homology to predicted sequence of rat secretogranin III, 511 Vitamin D receptors identification in choroid plexus and ependyma (hamster, mouse, rat), 145 Z Zimeldine reduction of preprotachykinin (rat), 139 Zimelidine, see Zimeldine
mRNA
in adult
medullary
raphe
nuclei
AND CELLULAR
NEUROSCIENCES
2,528~534
(1991)
Subject Index for Volume 2 A
FASEB Summer Research Conferences: 1991 Schedule and Organizers, 86 First International Symposium on Neurobiology and Neuroendocrinology of Aging, Bregenz, Austria, July 1992, 274,446 George B. Koelle Symposium on Cholinergic System, Philadelphia, Pennsylvania, October 1991, 87 International Congress on Growth Hormone and Somatomedins during Lifespan, Satellite of N.I.C.E. 1992, Milan, Italy, September 1992,447 Keystone Symposium on Molecular and Cellular Biology, 1992, 361 Molecular Aspects of Autoimmunity (International Meeting with Emphasis on Dysthyroid Ophthalmology, Thyroid Autoimmunity, and Type I Diabetes), Mainz, Germany, August 1992, 275 Ninth International Congress of Endocrinology, Nice, France, AugustSeptember 1992,362 Satellite Symposium of IXth International Congress of Endocrinology (Melatonin and the Pineal Gland: From Basic Science to Clinical Application), Paris, France, September 1992, 362 2nd International Workshop on Insulin-Like Growth Factor Binding Proteins, Opio, France, August 1992,361 Seventh International Symposium on Facial Nerve, Cologne, Germany, June 1992,274 Summer Neuropeptide Conference: Tentative Program, Cape Cod, Massachusetts, August 1992, 86 12th International Congress on Animal Reproduction, The Hague, The Netherlands, August 1992,447 XXIII Congress of International Society of Psychoneurcendocrinology (ISPNE), Madison, Wisconsin, August 1992, 275 Antibodies monoclonal, against dopamine-releasing protein, induction of arrested fetal development, reduced brain catecholamines, and increased adrenal weight (rat), 410 APl complex in PC12 cells, protein composition, variation after induction by nerve growth factor and TPA, 253 Arcuate nucleus pro-opiomelanocortin gene expression, inhibition by activation of GABA*-benzodiazepine receptor complex (rat), 440 tachykinin expression during continuous estrogen replacement: reduction of neurokinin B (rat), 299 ATPase Na,K-, (Y and @ subunit isoforms, mRNA expression in cochlea (rat), 179 Atria1 natriuretic peptide and endothelin, review: interactions in central nervous system and periphery, 189 Atria1 natriuretic peptide receptors guanylate cyclase-coupled, evidence for presence on neurohypophysial pituicytes (rat), 363 Axons goldfish Mauthner cells and rat dorsal and ventral roots, local protein synthesis in vitro, 384 growing, in cultured hippocampal neurons, association with microtubule-associated protein MAPlB (rat), 39
Acetylcholine receptors muscarinic m2 and m3, mRNAs, different responses to microtubule-affecting drugs (rat), 315 m3, mRNA levels, maintenance, role of microtubule structure (rat), 123 nicotinic, expression by TE671/RD cells, effects of second messenger modulation and sodium butyrate treatment (human), 52 Acetylcholinesterase activity and localization in denervated ductus deferens (guinea pig), 202 ACTH, see Adrenocorticotropin Activin production and action, molecular basis, review, 449 Adrenalectomy time- and region-dependent effect on neuropeptide gene expression in hippocampus and striatum (rat), 485 transforming growth factor 81 mRNA in brain of affected rats, reduction by corticosterone, 221 Adrenal gland increased weight in neonatal rata injected with monoclonal antibodies against dopamine-releasing protein, 410 Adrenal medulla chromaffin vesicles, isolation of tetradecapeptide with strong homology to predicted sequence of rat secretogranin III (bovine), 511 cultured cells, proenkephalin gene expression, regulation by angiotensin (bovine), 213 nuclear proteins, cholinergic agonist-induced binding to rat preproenkephalin promoter, 517 Adrenergic receptors a and 8, mRNAs, localization in brain and peripheral tissues with in situ hybridization (rat), 344 Adrenocorticotropin secretion by corticotropes in mixed and enriched cultures, enhancement by epidermal growth factor (rat), 235 y-Aminobutyric acid receptors GABAA -benzodiazepine receptor complex, activation, inhibition of proopiomelanocortin gene expression in arcuate nucleus (rat), 440 y2 subunit, alternatively spliced forms, localization and functional expression (murine brain, Xenopus oocytes), 338 Amygdala kindling, and electroconvulsive seizures, effects on expression of corticotropin-releasing hormone in brain (rat), 103 Androgen receptors encoding gene, expression in central nervous system: evidence for two mRNA transcripts (rat), 117 Angiotensin-converting enzyme, see Dipeptidyl carboxypeptidase I Announcements Conference on Neurohypophysis: A Window on Brain Function, Hanover, New Hampshire, July 1992,446 8th International Conference on Second Messengers and Phosphoproteins: Biology and Medicine of Signal Transduction, Glasgow, Scotland, August 1992,274 Eleventh Annual Lexington Hormone Research Symposium, Lexington, Kentucky, May 1992,361 1044-7431/91$3.00 Copyright 0 1991 by Academic Press, Inc. All rights of reproduction in any form reserved.
I3 Bacteria Escherichia factor, 528
coli, 369
expression
of recombinant
rat
ciliary
neurotrophic
SUBJECT Basal ganglia detection of high levels of Goif proteins (rat), 66 Behavior sexual, see Sexual behavior Benzodiazepine receptors -GABA, receptor complex, activation, inhibition of pro-opiomelanocortin gene expression in arcuate nucleus (rat), 440 Bradykinin modulation of electrophysiology of cultured sensory neurons through pertussis toxin-insensitive G protein (rat), 21 Brain, see also specific regions (Y- and &adrenergic receptor mRNA, localization with in situ hybridization (rat), 344 catecholamine levels, effects of monoclonal antibodies against dopamine-releasing protein (neonatal rat), 410 expression of angiotensin converting enzyme gene, enhancement by converting enzyme inhibitors (rat), 13 corticotropin-releasing hormone gene demonstration by in situ hybridization analysis (mouse), 266 effects of amygdala kindling and electroconvulsive seizures (rat), 103 functional foreign gene after in uivo transfer via herpes simplex virus type 1 defective viral vector (adult rat), 320 glucose transporter gene, effects of chronic insulin-induced hypoglycemia, fasting, and diabetes (rat), 244 pro-opiomelanocortin and gonadotropin-releasing hormone genes, pubertal changes (male monkey), 31 GABA* receptor y2 subunit, alternatively spliced forms, localization (mouse), 338 melatonin binding sites, distribution (goldfish), 78 transforming growth factor pl mRNA levels, decrease after glucocorticoid treatment in adrenalectomized rats, 221 Brain stem tryptophan hydroxylase gene expression, post-transcriptional control (rat), 71 Butyrylcholine esterase, see Cholinesterase
C Calcium channels in cultured sensory neurons, modulation by bradykinin through pertussis toxin-insensitive G protein (rat), 21 Captopril enhancement of neuronal angiotensin converting enzyme gene expression (rat), 13 Carbachol and sodium fluoride, differential effects on phosphoinositide metabolism in PC12 cells, 377 Castration effects on pretranslational expression of preoptic regulatory factor 1 mRNAs in brain and liver (rat), 395 Catecholamines cerebral, in neonatal rats, effects of monoclonal antibodies against dopamine-releasing protein, 410 Cell lines medulloblastoma, TE671/RD, nicotinic acetylcholine receptor expression, effects of second messenger modulation and sodium butyrate treatment (human), 52 neural, RT4, differential expression of homeobox genes (rat), 172 Central nervous system, see also speci& regions androgen receptor gene expression: evidence for two mRNA transcripts (rat), 117 fl-endorphin administration, regulation of insulin-induced ornithine decarboxylase expression in liver (neonatal rat), 1 Cerebellum granule cells, see Granule cells
529
INDEX
Cerebral cortex preoptic regulatory factor 1 mRNA levels, effects of hypophysectomy and castration (rat), 395 Cholecystokinin gene expression in hippocampus and striatum, time- and regiondependent effect of adrenalectomy (rat), 465 Choline acetyltransferase activity and localization in denervated ductus deferens (guinea pig), 202 Cholinesterase activity and localization in denervated ductus deferens (guinea pig), 202 Choroid plexus vitamin D receptors, identification (hamster, mouse, rat), 145 Ciliary neurotrophic factor recombinant, expression in Escherichia coli and synergy with basic fibroblast growth factor (rat), 369 Clorgyline reduction of preprotachykinin mRNA in adult medullary raphe nuclei (rat), 139 Cochlea expression of mRNAs encoding Na,K-ATPase (Y and fi subunit isoforms (rat), 179 Colchicine and fi-lumicolchicine and taxol, differential responses of m2- and m3muscarinic acetylcholine receptor mRNAs (rat), 315 Converting enzyme inhibitors enhancement of neuronal angiotensin converting enzyme gene expression (rat), 13 Corpus striatum and hippocampus, neuropeptide gene expression, time- and regiondependent effect of adrenalectomy (rat), 465 inducible preproenkephalin DNA-binding proteins, identification (rat), 427 Corticosterone induced decrease in transforming growth factor 81 mRNA in brain of adrenalectomized rats, 221 Corticotropes ACTH secretion and pro-opiomelanocortin mRNA expression in mixed and enriched cultures, enhancement by EGF (rat), 235 Corticotropin-releasing hormone encoding gene, nucleotide sequence and expression in brain (mouse), 266 expression in brain, effects of amygdala kindling and electroconvulsive seizures (rat), 103
D Degeneration and regeneration, nerve terminals in pituitary pars intermedia after 6-hydroxydopamine treatment (rat), 418 Denervation ductus deferens, effect on cholmesterases and choline acetyltransferase (guinea pig), 202 Desensitization D1 dopamine receptor: role of CAMP-dependent and receptor-specific protein kinases (human), 464 Development associated expression of class II j3-tubulin mRNA in hypothalamus, sex-related difference (rat), 130 fetal, effects of monoclonal antibodies against dopamine-releasing protein (rat), 410 pubertal changes in pro-opiomelanocortin and gonadotropin-releasing hormone gene expression in brain (male monkey), 31 Diabetes effect on glucose transporter gene expression in brain (rat), 244
530
SUBJECT
Dibutyryl cyclic AMP induction of differentiation and reduction of opioid receptor binding activity in N4TGl neuroblastoma cells, 284 and/or PMA, and sodium butyrate treatment, effects on nicotinic acetylcholine receptor expression by TE671/RD cells (human), 52 Differentiation N4TGl neuroblastoma cells, induction by insulin-like growth factor I and dibutyryl CAMP, 284 sexual, see Sexual differentiation Dipeptidyl carboxypeptidase I neuronal, gene expression, enhancement by converting enzyme inhibitors (rat), 13 DNA praproenkephalin, inducible striatal proteins binding to, identification (rat), 427 Dopamine receptors Di, desensitization: role of CAMP-dependent and receptor-specific protein kinases (human), 464 Dorsal root and ventral root, local axonal protein synthesis in vitro, comparison with goldfish Mauthner cell axons (rat), 384 Ductus deferens denervated, cholinesterases and choline acetyltransferase in, activity and localization (guinea pig), 202 E EGF, see Epidermal growth factor fl-Endorphin central nervous system, regulation of insulin-induced ornithine decarboxylase expression in liver (neonatal rat), 1 Endothelin and atria1 natriuretic peptide, review: interactions in central nervous system and periphery, 189 Ependyma vitamin D receptors, identification (hamster, mouse, rat), 145 Epidermal growth factor enhancement of ACTH secretion and pro-opiomelanocortin mRNA expression by corticotropes in mixed and enriched cultures (rat), 235 Estrogen continuous replacement, effect on tachykinin expression in arcuate nucleus: reduction of neurokinin B (rat), 299 Estrous cycle preprosomatostatin mRNA levels in hypothalamic periventricular nucleus during, variations (rat), 294 F Fasting effect on glucose transporter gene expression in brain (rat), 244 Fetus development, arrest by monoclonal antibodies against dopamine-releasing protein (rat), 410 Fihroblast growth factor basic, and recombinant rat ciliary neurotrophic factor expressed in Escherichia coli, synergetic effects on cultured neurons, 369 effect on N4TGl neuroblastoma cell differentiation and opioid receptor binding activity, 284 Fibroblasts L cell line with CAMP-responsive reporter construct, in screening ligands binding to cloned G,- or Gi-coupled receptors (mouse), 331 renal and L929 cell line, nerve growth factor gene expression: role of downstream AP-1 element in basal and modulated transcription (mouse), 157
INDEX Follicle-stimulating hormone cy and /3 subunits, steady-state mRNA levels in superfused pituitary cell cultures, enhancement by pulsatile GnRH stimulation (rat), 277 FSH, see Follicle-stimulating hormone G GABA receptors, see y-Aminobutyric acid receptors fl-Galactosidase encoding gene, foreign, expression in adult brain after in uiuo transfer via herpes simplex virus type 1 defective viral vector (rat), 320 Ganglion cells retinal, GAP-43 mRNA levels during regeneration, post-transcriptional regulation (goldfish), 402 Genes androgen receptor, expression in central nervous system: evidence for two mRNA transcripts (rat), 117 angiotensin-converting enzyme, neuronal expression, enhancement by converting enzyme inhibitors (rat), 13 brain-derived neurotrophic factor, expression in brain tumors (human), 168 corticotropin-releasing hormone, nucleotide sequence and expression in brain (mouse), 266 glucose transporter, expression in brain, effects of chronic insulininduced hypoglycemia, fasting, and diabetes (rat), 244 homeobox, differential expression in neural cell lines (rat), 172 lacZ, foreign, expression in adult brain after in uiuo transfer via herpes simplex virus type 1 defective viral vector (rat), 320 nerve growth factor, expression in brain tumors (human), 168 fibroblasts: role of downstream AP-1 element in basal and modulated transcription (mouse), 157 neuropeptide, expression in hippocampus and striatum, time- and region-dependent effect of adrenalectomy (rat), 485 oncogenes v-src, c-Ha-ras, and v-mos, retroviral transfer, in establishment of Schwann cell lines (mouse, rat), 6 oxytocin, promoter, identification of &-acting regulatory elements (human), 501 potassium channel, families in mammals, review: molecular basis of K+ channel diversity, 89 preproenkephalin, promoter, cholinergic agonist-induced binding to adrenomedullary nuclear proteins (rat), 517 preprosecretogranin III, encoded internal sequence, strong homology in tetradecapeptide isolated from bovine adrenal medulla chromaffin vesicles (rat), 511 proenkephalin expression in adrenal medullary cells, regulation by angiotensin (bovine), 213 and prodynorphin, expression in anteroventral periventricular nucleus, role of sexual differentiation and hormonal regulation (rat), 473 pro-opiomelanocortin expression in arcuate nucleus, inhibition by activation of GABAAbenzodiazepine receptor complex (rat), 440 and gonadotropin-releasing hormone, expression in brain, pubertal changes (male monkey), 31 tryptophan hydroxylase, expression in brain stem and pineal gland, post-transcriptional control (rat), 71 tyrosine hydroxylase, encoded products in neocortex, neuronal localization (human), 228 Gene transfer in adult brain in uiuo via herpes simplex virus type 1 defective viral vector, subsequent expression of functional foreign protein (rat), 320 Glucocorticoids inhibitory control of transforming growth factor fll-regulated actions in brain (rat), 221
SUBJECT Glucose transporters gene expression in brain, effects of chronic insulin-induced bypoglycemia, fasting, and diabetes (rat), 244 GLUT1 and GLUT3, expression in cultured cerebellar neurons: evidence for neuron-specific GLUT3 expression (rat), 351 GnRH, see Gonadotropin-releasing hormone Gonadotropin-releasing hormone gene expression in brain, pubertal changes (male monkey), 31 pulsatile stimulation, enhancement of steady-state mRNA levels for FSHj3, LH& and (Y subunits in superfused pituitary cell cultures (rat), 277 G protein-coupled receptors G.- or G,-coupled, cloned, ligands binding to, screening (murine L cells), 331 G proteins G,,r, detection in basal ganglia in high levels (rat), 66 pertussis toxin-insensitive, role in bradykinin modulation of physiology of cultured sensory neurons (rat), 21 Granule cells cerebellar cultured, expression of glucose transporters GLUT1 and GLUTB: evidence for neuron-specific GLUT3 expression (rat), 351 muscarinic acetylcholine receptor mRNAs m2 and m3, different responses to microtubule-affecting drugs (rat), 315 m3, maintenance, role of microtubule structure (rat), 123 Guanylate cyclase coupled atria1 natriuretic peptide receptors, evidence for presence on neurohypophysial pituicytes (rat), 363
H Herpes simplex virus type 1 defective vector, application to transfer of foreign gene to adult rat brain in vivo, 320 Hippocampus [3H]inositol phosphate formation in slices, luteinizing hormonereleasing hormone-induced facilitation (rat), 208 and striatum, neuropeptide gene expression, time- and region-dependent effect of adrenalectomy (rat), 485 Homeobox containing genes, differential expression in neural cell lines (rat), 172 Hybridization in situ in analysis of interleukin-10 mRNA induction by methamphetamine in hypothalamus (rat), 259 in localization of (Y- and @-adrenergic receptor mRNA in brain and peripheral tissues (rat), 344 6-Hydroxydopamine induced degeneration of nerve terminals in pituitary pars intermedia, subsequent regeneration (rat), 418 Hypoglycemia insulin-induced, chronic, effect on glucose transporter gene expression in brain (rat), 244 Hypophysectomy effects on pretranslational expression of preoptic regulatory factor 1 mRNAs in brain, liver, and testis (rat), 395 Hypothalamus arcuate nucleus, see Arcuate nucleus developmental expression of class II fl-tubulin mRNA, sex-related difference (rat), 130 interleukin-1@ mRNA induction by metbamphetamine, in situ hybridization analysis (rat), 259 periventricular nucleus, see Periventricular nucleus preoptic regulatory factor 1 mRNA levels, effects of hypopbysectomy and castration (rat), 395 ventromedial, protein patterns, correlation with progesterone-dependent sexual behavior (adult female rat), 491
531
INDEX I
Inhibin production and action, molecular basis, review, 449 Inositol phosphate ‘H-labeled, formation in hippocampal slices, luteinizing hormonereleasing hormone-induced facilitation (rat), 208 Insulin effact on N4TGl neuroblastoma cell differentiation and opioid receptor binding activity, 284 induced hypoglycemia, effect on glucose transporter gene expression in brain (rat), 244 induced ornithine decarboxylase expression in liver, regulation by central nervous system j%endorphin (neonatal rat), 1 Insulin-like growth factor I induction of differentiation and reduction of opioid receptor binding activity in N4TGl neuroblastoma cells, 284 Interleukin-10 mRNA, induction by methamphetamine in hypothalamus, in situ hybridization analysis (rat), 259 Ion channels calcium, see Calcium channels nonselective, in cultured sensory neurons, modulation by bradykinin through pertussis toxin-insensitive G protein (rat), 21 potassium, see Potassium channels
K Kindling amygdala, and electroconvulsive seizures, effects on expression corticotropin-releasing hormone in brain (rat), 103
of
LH, see Luteinizing hormone Ligand screening assay ligands binding to cloned G,- or Gi-coupled receptors (murine L cells), 331 Lisinopril enhancement of neuronal angiotensin converting enzyme gene expression (rat), 13 Liver insulin-induced ornithine decarboxylase expression, regulation by central nervous system &endorphin (neonatal rat), 1 preoptic regulatory factor 1 mRNA levels, effects of hypophysectomy and castration (rat), 395 &Lumicolchicine and colchicine and taxol, differential responses of m2- and m3-muscarinic acetylcholine receptor mRNAs (rat), 315 Luteinizing hormone a! and fl subunits, steady-state mRNA levels in superfused pituitary cell cultures, enhancement by pulsatile GnRH stimulation (rat), 277 Luteinizing hormone-releasing hormone facilitation of [3H]inositol phosphate formation in hippocampal slices (rat), 208
M Mauthner cells goldfish, local axonal protein synthesis in vitro, comparison with rat dorsal and ventral root axons, 384 Medullary raphe nuclei preprotachykinin mRNA levels, reduction by zimelidine and clorgyline (rat), 139 Melatonin binding sites in brain and pituitary, distribution (goldfish), 78
532
SUBJECT
Methamphetamine induction of interleukin-10 mRNA in hypothalamus, in situ hybridization analysis (rat), 259 Microtubules affecting drugs, differential responses of m2- and m3-muscarinic acetylcholine receptor mRNAs (rat), 315 associated protein MAPlB, association with growing axons in cultured hippocampal neurons (rat), 39 structure, role in maintenance of m3-muscarinic acetylcholine receptor mRNA levels (rat), 123 Muscles smooth, denervated, cholinesterases and choline acetyltransferase in, activity and localization (guinea pig ductus deferens), 202 N
Neocortex tyrosine hydroxylase gene products, neuronal localization (human), 228 Nerve growth factor and brain-derived neurotrophic factor, gene expression in brain tumors (human), 168 gene expression: role of downstream AP-1 element in basal and modulated transcription (murine fibroblasts), 157 and TPA, induction of PC12 cells, effect on composition of APl complex, 253 Nerves optic, regeneration, associated GAP-43 mRNA levels, post-transcriptional regulation (goldfish), 402 Nerve terminals in pituitary pars intermedia, degeneration and regeneration after 6hydroxydopamine treatment (rat), 418 Neurohypophysis pituicytes, evidence for presence of guanylate cyclase-coupled receptors for atria1 natriuretic peptide (rat), 363 Neurokinin B expression in arcuate nucleus, reduction by continuous estrogen replacement (rat), 299 Neurons angiotensin converting enzyme gene expression, enhancement by converting enzyme inhibitors (rat), 13 cultured, ciliary, synergetic effects of recombinant rat ciliary neurotrophic factor expressed in Esc/rcrichio coli and basic flbroblast growth factor (chicken), 369 differentiation, GAP-43 mRNA levels during, post-transcriptional regulation (goldfish, rat), 402 hippocampal, growing axons in culture, association with microtubuleassociated protein MAPlB (rat), 39 neocortical, localization of tyrosine hydroxylase gene products (human), 228 sensory, electrophysiology in culture, modulation by bradykinin through pertussis toxin-insensitive G protein (rat), 21 Neuropeptide Y gene expression in hippocampus and striatum, time- and region-dependent effect of adrenalectomy (rat), 485 Neurotrophic factors brain-derived, and nerve growth factor, gene expression in brain tumors (human), 168 ciliary, see Ciliary neurotrophic factor Nicotine induction of binding of adrenomedullary nuclear proteins to rat preproenkephalin promoter, analysis, 517 Nuclei, see specific nuclei Nucleoproteins adrenomedullary, cholinergic agonist-induced binding to rat preproenkephalin promoter, 517 Nucleotide sequence corticotropin-releasing hormone gene (mouse), 266
INDEX 0 Oocytes
functional expression of alternatively spliced forms of GABA* receptor yz subunit (Xenopus laevis), 338 Opioid receptors binding activity in N4TGl neuroblastoma cells, reduction by insulinlike growth factor I and dibutyryl CAMP, 284 Ornithine decarboxylase insulin-induced expression in liver, regulation by central nervous system B-endorphin (neonatal rat), 1 Oxotremorine induction of binding of adrenomedullary nuclear proteins to rat preproenkephalin promoter, analysis, 517 Oxytocin gene promoter, identification of &-acting regulatory elements (human), 501
P
Periventricular nucleus anteroventral, prodynorphin and proenkephalin gene expression, role of sexual differentiation and hormonal regulation (rat), 473 preprosomatostatin mRNA levels, variations during estrous cycle (rat), 294 Phorboll2-myristate 13-acetate and/or dbcAMP, and sodium butyrate treatment, effects on nicotinic acetylcholine receptor expression by TE671/RD cells (human), 52 Phosphoinositides metabolism in PC12 cells, differential sensitivity to sodium fluoride and carbachol treatments, 377 Pineal gland tryptophan hydroxylase gene expression, post-transcriptional control (rat), 71 Pituicytes presence of guanylate cyclase-coupled receptors for atrial natriuretic peptide, evidence (rat), 363 Pituitary anterior, derived corticotropes, ACTH secretion and pro-opiomelanocortin mRNA expression in mixed and enriched cultures, enhancement by EGF (rat), 235 intermediate lobe, nerve terminals, degeneration and regeneration after 6-hydroxydopamine treatment (rat), 418 melatonin binding sites, distribution (gold&h), 78 posterior lobe, see Neurohypophysis superfused cell cultures, steady-state mRNA levels for FSHB, LHj3, and (Y subunits, enhancement by pulsatile GnRH stimulation (rat), 277 Placenta preoptic regulatory factor 1 mRNA, analysis (human), 395 PMA, see Phorbol 12-myristate 13-acetate Polyribosomes synaptoneurosomal, protein translation, triggering by K+ stimulation (rat), 305 Potassium channels gene families in mammals, review: molecular basis of K+ channel diversity, 89 Potassium ions stimulation of synaptoneurosomal polyribosomes, associated triggering of protein translation (rat), 305 Preoptic regulatory factor 1 mRNAs, pretranslational expression, direction by intrinsic and extrinsic modulators (human, rat), 395 Preprodynorphin gene expression in hippocampus and striatum, timeand regiondependent effect of adrenalectomy (rat), 485
SUBJECT Preproenkephalin gene expression in hippocampus and striatum, time- and regiondependent effect of adrenalectomy (rat), 485 gene promoter choline&c agonist-induced binding to adrenomedullary nuclear proteins (rat), 517 inducible striatal proteins binding to, identification (rat), 427 Preprotacbykinin mRNA levels in adult medullary raphe nuclei, reduction by zimelidine and clorgyline (rat), 139 Prodynorphin gene expression in anteroventral periventricular nucleus, role of sexual differentiation and hormonal regulation (rat), 473 Proenkephalin gene expression in adrenal medullary cells, regulation by angiotensin (bovine), 213 anteroventral periventricular nucleus, role of sexual differentiation and hormonal regulation (rat), 473 Progesterone dependent sexual behavior, and protein patterns in ventromedial hypothalamus, correlation (adult female rat), 491 Promoters oxytocin gene, identification of &-acting regulatory elements (human), 501 preproenkephalin gene, choline@ agonist-induced binding to adrenomedullary nuclear proteins (rat), 517 Pro-opiomelanocortin gene expression in arcuate nucleus, inhibition by activation of GABAA-benzodiazepine receptor complex (rat), 440 brain, pubertal changes (male monkey), 31 mRNA expression by corticotropes in mixed and enriched cultures, enhancement by epidermal growth factor (rat), 235 Protein kinases CAMP-dependent and receptor-specific, role in desensitization of D1 dopamine receptor (human), 464 Proteins composition in APl complex, variation after induction by nerve growth factor and TPA (PC12 cells), 253 dopamine-releasing, monoclonal antibodies, induction of arrested fetal development, reduced brain catecholamines, and increased adrenal weight (rat), 410 growth-associated, GAP-43, mRNA levels during neuronal differentiation and nerve regeneration, post-transcriptional regulation (goldfish, rat), 402 microtubule-associated, MAPlB and MAPS, distribution during differentiation of cultured hippocampal neurons, comparison (rat), 39 preproenkephalin DNA-binding, inducible, identification in striatum (rat), 427 Protein synthesis associated mRNA translation in synaptoneurosomal polyribosomes, triggering by K+ stimulation (rat), 305 local axonal, in goldfish Mauthner cell axon and rat dorsal and ventral root axons in vitro, 384 in ventromedial hypothalamus of adult female rat, correlation with progesterone-dependent sexual behavior, 491 R Raphe medullary, nuclei, preprotachykinin mRNA levels, reduction by zimelidine and clorgyline (rat), 139 Regeneration nerve terminals in pituitary pars intermedia after 6-hydroxydopamine treatment (rat), 418 retinal ganglion cells, associated GAP-43 mRNA levels, post-transcriptional regulation (goldfish), 402
533
INDEX
RNA messenger c~- and @-adrenergic receptors, localization in brain and peripheral tissues with in situ hybridization (rat), 344 androgen receptor, evidence for two forms in central nervous system (rat), 117 class II @-tubulin, developmental expression in hypothalamus, sexrelated difference (rat), 130 FSH& LH& and OL subunits, steady-state levels in superfused pituitary cell cultures, enhancement by pulsatile GnRH stimulation (rat), 277 GAP-43, levels during neuronal differentiation and nerve regeneration, post-transcriptional regulation (gold&h, rat), 402 interleukin-l/3, induction by methamphetamine in hypothalamus, in situ hybridization analysis (rat), 259 muscarinic acetylcholine receptors m2 and m3, different responses to microtubule-affecting drugs (rat), 315 m3, maintenance of levels in cerebellar granule cells, role of microtubule structure (rat), 123 Na,K-ATPase (Y and j3 subunit isoforms, expression in cochlea (rat), 179 preoptic regulatory factor 1, pretranslational expression, direction by intrinsic and extrinsic modulators (human, rat), 395 preprosomatostatin, levels in hypothalamic periventricular nucleus, variations during estrous cycle (rat), 294 preprotachykinin, levels in adult medullary raphe nuclei, reduction by zimelidine and clorgyline (rat), 139 transforming growth factor 81, reduction in brain in response to glucocorticoid treatment of adrenalectomized rats, 221 translation in synaptoneurosomal polyribosomes, triggering by K+ stimulation (rat), 305
S Schwann cells cell lines, establishment by oncogene transfer (mouse, rat), 6 Second messenger systems involved in angiotenein regulation of proenkephalin gene expression in adrenal medullary cells, analysis (bovine), 213 modulation, and sodium butyrate treatment, effects on nicotinic acetylcholine receptor expression by TE671/RD cells (human), 52 Secretogranin III predicted sequence, strong homology to tetradecapeptide isolated from bovine adrenal medulla chromaffin vesicles (rat), 511 Seizures amygdala kindled and electroconvulsive, effects on expression of corticotropin-releasing hormone in brain (rat), 103 Sex differences developmental expression of class II j3-tubulin mRNA in hypothalamus (rat), 130 Sexual behavior progesterone-dependent, and protein patterns in ventromedial hypothalamus, correlation (adult female rat), 491 Sexual differentiation and hormonal regulation, role in prodynorphin and proenkephalin gene expression in anteroventral periventricular nucleus (rat), 473 Sodium butyrate and second messenger modulation, effects on nicotinic acetylcholine receptor expression by TE671/RD cells (human), 52 Sodium fluoride and carbachol, differential effects on phosphoinositide metabolism in PC12 cells, 377 Somatostatin precursor mRNA . levels in hypothalamic nucleus, _. ~. periventricular variations during estrous cycle (rat), 294
534
SUBJECT
Steroids reproductive, and sexual differentiation, role in prodynorphin and proenkephalin gene expression in anteroventral periventricular nucleus (rat), 473 Synaptoneurosomes polyribosomes in, protein translation, triggering by K+ stimulation (rat), 305 T Tachykinins expression in arcuate nucleus during continuous estrogen replacement: reduction of neurokinin B (rat), 299 Taxol and colchicine and fi-lticolchicine, differential responses of m2- and m3-muscarinic acetylcholine receptor mRNAs (rat), 315 Testis pretranslational preoptic regulatory factor 1 mRNA levels, effects of pituitary and testicular factors (rat), 395 12-0-Tetradecanoylphorbol-13-acetate and nerve growth factor, induction of PC12 cells, effect on composition of APl complex, 253 Tetradecapeptide isolated from bovine adrenal medulla chromaffin vesicles, strong homology to predicted sequence of rat secretogranin III, 511 Tissues peripheral, (Y- and /3-adrenergic receptor mRNAs, localization with in situ hybridization (rat), 344 TPA, see 12-0-Tetradecanoylphorbol-13-acetate Transcription nerve growth factor gene, basal and modulated, role of downstream AP-1 element (murine fibroblasts), 157 Transforming growth factor 81 mRNA reduction in brain in response to glucocorticoid treatment of adrenalectomized rata, 221 Translation proteins in synaptoneurosomal polyribosomes, triggering by K+ stimulation (rat), 305 Tryptophan 5-hydroxylase, see Tryptophan 5monooxygenase Tryptophan 5-monooxygenase encoding gene, expression in brain stem and pineal gland, post-transcriptional control (rat), 71 &Tubulin class II, mRNA, developmental expression in hypothalamus, sexrelated difference (rat), 130
INDEX Tumor cells neurohlastoma, N4TG1, differentiation and opioid receptor binding activity, effects of fibroblast growth factor, insulin, insulin-like growth factor, and Bt,cAMP (mouse), 284 neurotumor, SK-M-MC, D, dopamine receptors in, desensitization: role of CAMP-dependent and receptor-specific protein kinases (human), 464 pheochromocytoma, PC12 APl complex protein composition, variation after induction by nerve growth factor and TPA (rat), 253 GAP-43 mRNA levels during differentiation, post-transcriptional regulation (rat), 402 phosphoinositide metabolism, differential sensitivity to sodium fluoride and carbachol treatments (rat), 377 Tumors brain, brain-derived neurotrophic factor and nerve growth factor gene expression (human), 168 Tyrosine hydroxylase gene products in neocortex, neuronal localization (human), 228 V Vectors defective, herpes simplex virus type 1, application to transfer of foreign gene to adult rat brain in uiuo, 320 oncogenic, application in establishment of Schwann cell lines (mouse, rat), 6 Ventral root and dorsal root, local axonal protein synthesis in vitro, comparison with goldfish Mauthner cell axons (rat), 384 Vesicles chromaffin, from bovine adrenal medulla, isolation of tetradecapeptide with strong homology to predicted sequence of rat secretogranin III, 511 Vitamin D receptors identification in choroid plexus and ependyma (hamster, mouse, rat), 145 Z Zimeldine reduction of preprotachykinin (rat), 139 Zimelidine, see Zimeldine
mRNA
in adult
medullary
raphe
nuclei