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Subject index to volume 36
PII: SOO28-3908(97)00204-9
SUBJECT INDEX TO VOLUME 36
A Acetaldehyde Acetylcholine ACPD ( 1-aminocyclo-pentaneAdenine nucleotides Adenosine Adenosine A, receptor Adenosine A,, receptor Adenosine A, receptor Adenosine receptors Adenylyl cyclase ADP /3- Adrenergic receptor a2 Adrenergic receptor Afterhyperpolarization @ Agatoxin IVA Ageing Alcohol withdrawal Aldosterone Allosteric modulation Amino acid sequences Amino acids (S)-2- Amino-4-phosphonobutanoic
y-Aminobutyric
225 39, 241, 281, 295, 1119, 1733, 1783, 1789 1047,1533 1,3dicarboxylic acid) 1167, 1221 161, 169, 1127, 1149, 1157, 1201, 1253 161, 1211 1309,1319 1157 1141 713,1141,1157 1189 75 993 1653 865 973 1369 763 649 513 225 13,21, 153, 313, acid (L-AP4) 335, 845, 1517
acid (see GABA) 31 l- Aminocyclopropanecarboxylic acid (ACPC) 1393 AMPA-NMDA receptor interaction 335, 1489, 1503 AMPA receptor 1393 AMPA/kainate receptor desensitization 787, 1471 Amphetamine 735 Amygdala 281 Analgesia 1779 Anesthesia 941,981 Anoxia 1079 Antibodies 951, 1369 Anticonvulsant 475 Antidepressant 467 Antidepressant activity 177 Antioxidants 345,405 Antisense 389,439,601,609,793, 1071, 1089, 1355 Anxiety 707, 1369 Anxiolytic 1065 AP- 1 transcription factor 1065 AP-3 transcription factor 353 APNEA 811, 1023, 1149 Apoptosis 951 ARL 12495AA 1425 Arthritis 697 Associative olfactory task 1127, 1149, 1181, 1189, 1221, 1229, 1277, 1295 ATP 1253 ATP receptors 1269 ATP-activated channel 281 Atropine XIII
Subject Index
XIV
Autoradiography tram- Azetidine-2,4_dicarboxylic
acid (tADA)
217,217,779, 1243 261,1533
B Baclofen Bacterial expression Baculovirus expression system Bartters syndrome Basolateral amygdala Behaviour Benzodiazepines Benzodiazepine receptors 5-{3-[((2S)-l,4-Benzodioxan-2-ylme~yl)~no]propoxy}-1,3-benzodioxole Benzomorphan 6- Benzoylheteratisine Bicuculline BIMUl Bradykinin Bradykinin receptors Brain development Buspirone BW 723C86 BZD receptor (type 2)
1387 1377 21 755 1555 233,241,631 389,601,823, 1641 1641,1659 (MKC-242)
1733 51 1039 1653, 1659, 1705 697 1009 115 445 1089 233 1641
C CA1 Caffeine Calcium channel Calcium channel (P-type) Calcium channel blockers Calcium channels Calcium currents Calcium currents (presynaptic) Calcium mobilization Calcium permeability Calcium-dependent release Calcium/calmodulin-dependent CAMP CAMP-dependent protein kinase Cannabinoids Capsaicin Carbachol p Carboline 5- Carboxamidotryptamine Caspases Catecholamines Caudate nucleus Caudate-putamen L- CCG I CCK, receptor Cell death Cell permeabilization Cerebellar nuclei Cerebellum
protein kinase II
1533, 1539 1309 1796 405 865 353,405,865, 895, 1795 115, 195 185 125,429 1253 1253 1763 145, 153, 353,429,721, 933, 1201, 1631 209 1387 1417 1771 1771 83,535 1149 1783 577 779, 1589 1 1679 1295 1285 75 75,401,411,865
Subject Index CGMP CGP 37849 CGP 40116 CGP-3955 1 Chelerytrine chloride Chimeras Chinese hamster ovary cells (CHO cells) (JW)-2- Chloro-5-hydroxyphenylglycine (CHFG) 4 C3HPG m- Chlorophenylbiguanide Chlorpromazine Cholecystokin (CCK) receptors Cholecystokinin (CCK) Cholera toxin Choline uptake (high affinity) Cholinergic Cholinergic neurons Citalopram Cloning Clozapine CNQX Cobalt Cocaine Cochlea COMT inhibitor Concanavalin A Conditioned place preference u)- Conotoxin MVIIC @ Conotoxin GVIA CP-122 288 CP-93 129 S-4 CPG CR 2249 (4-amino-5-[4,4-dimethylcyclohexyl)amino]-5-oxopentanoic Craniofacial development CRF (corticotropin releasing factor) CRF, receptor CW, receptor Cultured dorsal root ganglion neurones Cyclic AMP (see CAMP) Cyclic AMP response element binding protein (CREB) Cyclooxygenase Cyclothiazide Cytochrome-c oxidase
xv 1393, 1405 31 1555 961 1047 1489 145, 153 1517 1533 665 665 389, 1679 389, 1679 1623 1741 281 1755 461,475 917 1689 1503 335 373,769 1269 363 1503 251 865 195 83,525 525 1047, 1533 acid) 1057 445 1439 1439 1439 195 1659 411 1009 335,1393, 1503 1665
D [%I dATPaS binding Daurisoline Deaminase Deliberate self harm Delta opioid receptor Dentate gyrus Depotentiation Deprenyl Desensitization
1243 107 169 439 1763 345,973 161, 1339 1455 1141,1303
Subject Index
XVI
Development Dialysis (2S,l’R,2’R,3’@-2-(2’,3’-
Dicarboxycyclopropyl)glycine Dihydropyridine
217 241 1517 1157 1047,1517 577,147l 917 39 1463
(DCG-IV)
(RS)-3,5- Dihydroxyphenylglycine (DHPG) 2,5- Dimethoxy-4-iodoamphetamine (DOI) Distribution DMPP DOM Dopamine Dopamine Dopamine Dopamine
251,787, (DA) agonists antagonists
Dopamine D, receptor Dopamine D, receptor Dopamine D, receptor Dopamine D, receptor Dopamine metabolism Dopamine receptors Dopamine release Dopaminergic neurones Dopaminergic supersensitivity Dorsal hippocampus Dorsal raphe nucleus Dorsal root ganglia Down Syndrome DPCPX DRG explants Drug Drug Drug Dura
discrimination reward screening mater
1115, 1455, 1471, 1571, 1679 373 1099 1099 93, 101,1679, 1689 93,769,779,787,999, 1689 787,999,1689 999 225 1689 1447 1653 1659 467 559,735 853, 1009 1549 1327 1755 373,147l 251 269 83,525
E Eating Ecto-apyrase Ecto-ATP diphosphohydrolase Ecto-ATPase Ecto-nucleotidase Ecto-phosphodiesterase Efficacy Electroconvulsive shock (ECS) Elevated plus-mare Elevated zero-maze Entorhinal cortex Environmental enrichment Ephedrine Epibatidine Epilepsy Epilepsy models Episodic ataxia Ethanol Eticlopride Excitotoxicity Exploratory behaviour
1725 1189 1189 1189 1189 1201 499 411 793, 1089 389 973 251 1417 1119 345,951,1393, 1405 1705 755 101, 1099 769, 1589 981 389
XVII
Subject Index
F 383 363 233,609 803 1755 1157 823 1285 1705 483 31 1201 411,1309,1779 467,475 917
Faecal pellets FDOPA Feeding d- Fenfluramine FK-506 Flavonoid Flunitrazepam Fluorescence imaging Fluoxetine Food deprivation Forced swimming test Forskolin c-fos Frontal cortex Functional expression
G G-proteins GABA GABA-glutamate interaction GABA-NMDA receptor interaction GABA, receptor GAB A, receptor channel GABA, receptor subunits GABAJbenzodiazepine receptor complex GABA, receptor Gabapentin GDP-j% Gene targeting Globus pallidus GluR5 GluR6 Glutamate Glutamate receptor Glutamatergic terminals Glycine Glycine, antagonists Glycine, partial agonists GR-127,935 GR113808 GR65630 Grooming (rat) GTP-YS [ssS]- GTPyS binding Guanine nucleotides Guinea pig
295,451,
1211, 1623,1747 941, 1387, 1789 1393 1405 63,823,941, 1377, 1405, 1611 1623, 1631 1377,1601, 1611, 1641 1071 1405 1369 1623 135 1309 853 853 305,401, 1517, 1571,1789 853 589 1057 1355 1355 83 671 665 1679 1623 451,499 1157 51,513,549,559, 1713
H Hair cell Hallucinogens Haloperidol HEK293 cells
1269 631, 1463 1689 1181
XVIII
Subject Index
Hemicholinium mustard Heteratisine Heterologous expression Hippocampal Hippocampal slice Hippocampus
1741 1039 569 1517 1057
systems
177,261,305,961, 31,319,345, 353,397,411,475,735, 823,831,951, 1039, 1201, 1339, 1393, 1405, 1477, 1517, 1533, 1539, 1549, 1705 115 Hoe 140 125 Homologous desensitization 1513 4C3 HPG 373, 383, 461,475, 489, 543, 549, 5- HT (5-hydroxytryptamine, serotonin) 569, 589, 621, 631,671, 681, 689, 713,721,735, 1697 475 5- HT autoreceptor 1713 5- HT autoreceptors 225 5- HT metabolism 1697 5- HT neuronal activity 419,489,543,577 5- HT receptors 803, 1221 5- HT release 373,461 5- HT reuptake inhibition 1725 5- HT syndrome 1079 5- HT-moduline 461,483 5- HT,, autoreceptor 483 5- HT,, autoreceptors midbrain 373,429,445,451,461,467,743, 1071, 5- HT,, receptor 1089, 1725, 1733 373,467,513,525,535, 1079 5- HT,, receptor 559 5- HT,,,,, autoreceptors 83,549 5-HT IB/lD receptor 513,525,535 5- HT,, receptor 535 5- HT,, receptor 631,793, 1471 5- HT, receptor 589 5- HT,, receptor 233,601 5- HT,, receptor 233,609,621,743 5- HT,, receptor 637.649,665 5- HT, receptor 671,681,689,697; 707,763 5- HT, receptor 713 5- HT, receptor 439,803 5- HT transporter 145,513,763,779, 1181 Human 419 Human genome 1433 Hydrocortisone 1733 8- Hydroxy-2-(di-n-propylamino)tetralin (8-OH-DPAT) 1571 No- Hydroxy-L-arginine 1659 6- Hydroxydopamine lesioning 649 5- Hydroxyindole 5- Hydroxytryptamine, 5- Hydroxytryptophan Hyoscyamine Hyperalgesia Hypoglycemia Hypotension Hypothalamus Hypothermia Hypoxia
see 5-HT accumulation
107,981,
483 281 1425 107 1779 1713 993 1327
XIX
Subject Index I IH
Immediate early genes Immortalized Immunocytochemistry Immunohistochemistry Immunophilin In situ hybridization Indomethacin Inflammation Input conductance Interleukins Intracellular calcium Intrastriatal injection Inverse agonism Inverse agonist Inward rectifier Ionomycin Ionophoresis Ionotropic glutamate receptor agonists Ischemia
721 1309 543 1079,1779 217, 1229, 1277 1755 217, 1277, 1309 1417 1295 169 1009 1747 1659 451 499 209 1763 489 1047 981,1031,1327,1796
K 1167 853, 1483, 1489, 1503 853, 1477 535,631 1141 1763 1763 1763
K562 erythroleukemia Kainate receptor Kainic acid Ketanserin Kinases KN62 KN92 KN93
L Learning Lewis rats Lidocaine Light/dark choice test Linopirdine Lisuride Lobeline Locomotor activity Long QT syndrome Long-term depression (LTD) Long-term memory Long-term potentiation (LTP) Loreclezole Loss of righting reflex Low Caz+/high Mg2+ LTP LY293558 LY294486 LY307452 LY354740 Lysergic-acid diethylamide
(LSD)
281,689,697,
1549, 1583 483 1031 793 1747 769 39 251,787, 1099 755 161,397,1517 697 345,823,961,973, 1339, 1533, 1539, 1549 1601 1099 1539 1539 1477 1477 1 1,933 713,147l
Subject Index
M 1747 1277 1319 845 1, 845, 1047, 1339, 1533 577 793 1269 601 735 735 217 217 961 281,689, 823, 1057, 1583 1549 1623, 1631 1689 981 1, 13, 21, 135, 145, 261, 265, 305, 313, 335,401, 589, 831, 845,933, 1047, 1339, 1511, 1517, 1533 577 Metergoline 325, 1665 Methamphetamine 941 Methohexital 313 @,!+a- Methyl-4-carboxyphenylglycine 313 (RS)-a- Methyl-4-phosphonophenylglycine 577 2- Methyl-5-HT 1561 N- Methyl-D-aspartate (NMDA) 1517 N- Methyl-D-aspartate (NMDA) receptor 1697 3,4- Methylenedioxymethamphetamine (MDMA) 1483 [sH]-(2S,4R)-4- Methylglutamate 853, 1483 4- Methylglutamate 763 Metoclopramide M-current Macrophage MAP kinase MAP4 MCPG mCPP MDL 100,907 Mechano-electrical transducer channel Medial amygdaloid nucleus Medial prefrontal cortex Median raphe nucleus Melanocortin-3 receptor Melanocortins Memantine Memory Mental retardation Mercury chloride Messenger RNA Metabolic stress Metabotropic glutamate (mGlu) receptors
mGluR, see metabotropic glutamate receptors mGluR receptor (group I) Mianserin 255,461,467,475,549,787, Microdialysis Microglia Mifepristone Migraine Mitochondria MK-801 Molecular modelling Monoamine oxidase B (MAO-B) Monocyte Monosynaptic IPSPs Morphine Morphine withdrawal Mossy fibre Motoneurone Mouse defense test battery (MDTB) MPP+ MPTP-induced parkinsonism Muscarine
1533 793 1295, 1393, 1405, 1455, 1697, 1733 1277, 1295 1433 83,525,569 1665 325,961 269 1455 1277 169 251 241 1477 313,721 793 993 363 1747
XXI
Subject Index Muscarinic receptor Muscimol Mutagenesis
N N lE- 115 neuroblastoma Naloxone NBQX Necrosis Neonatal Neuritogenesis Neuroblastoma Neurogenic inflammation Neuroleptics Neuromuscular transmission Neuronal differentiation Neuropathic pain Neuroprotection Neurotensin Neurotensin receptors NGlOS-15 cells NGF Nicotine Nicotinic acetylcholine receptor Nitric oxide Nitrobenzylthioinosine NMDA (N-methyl-o-aspartate) NMDA channels NMDA receptor NMDA receptor antagonists Nociception Nociceptor Non-NMDA receptors Noradrenaline NOS inhibitors Noxious stimulation Nucleoside transport Nucleus accumbens Nucleus tractus solitarius (NTS)
209,281,295,681 1387 637
649 1433 1503 1149 1327 811 811 83 1115, 1665 185 1755 1561 1796 93 1447 115 1319 1119, 1511, 1783 39,269, 1119 1393, 1405, 1417, 1571, 1583, 1589 1167 16,39, 161,265,397 319 831,951, 1057, 1517, 1561 241, 1355 743, 1047 1303 1503 75,993, 1057 1417 1425 1167 325, 1447 489
0 Obsessive-compulsive disorder Oestrogen 8- OH-DPAT Olfactory memory Oligonucleotides Ontogenesis Opioid receptors 6 Opioid receptor Opioids Optokinetic nystagmus Orbitofrontal cortex Osmotic mini-pump Oxygen radicals
483,577,
577 1433 1071, 1705 681 345 305 251 125, 1763 1109 135 577 1119 177
Subject Index
P Pl receptors P2 receptors P2X receptor P2X, receptor P2Y 1 receptor P2Y, receptor Pain Passive avoidance learning Patch-clamp electrophysiology PC12 cells PCP (phencyclidine) (-)- Penbutolol Pentobarbital Peptide Ca2+ channel blockers Pertussis toxin PET Pharmacological profiling Pharmacology Phenylglycine derivatives Phenylglycines Phenytoin pHook Phorbol ester Phosphatidylethanol Phosphatidylinositol phosphates Phospholipase C Phospholipase D Phosphorylation phOx antigen PK 11195 Plasticity Plus-maze Polyamine amides Polyamines Polymorphism Population spike Potassium channel Potentiation l- PP (1-(2-pyrimidinyl)-piperazine) Prefrontal cortex Preproenkephalin mRNA Preprotachykinin mRNA Presynaptic inhibition Proadifen Progesterone Propofol Prostaglandin E (EP) receptor Prostaglandin Ei Protein kinase Protein kinase A Protein kinase C Protein synthesis Pupillary response Purification Purinergic Purinergic receptors
1127 1221 1303 1285 1243 1181 281, 1009, 1425 961 1641 1319 1665 475 1611 195 1623 363 917 1796 933 13,265 1031 63 1631 295 1771 261, 1181, 1771 261,295, 305 411, 1377, 1631 63 1659 397, 1047 1355 185 185 439 1039 209 313,649, 1611 1089 589 325 325 845 1089 1433, 1783 941, 1611 1023 1023 295, 1377, 1631 1539 209, 1047 973 135 1211 1303 353, 1229, 1277 1127, 1269, 1277, 1181,
XXIII
Subject Index
107,865
Purkinje cell
Q
787
Quinelorane
R Rabbit brain synaptic membranes Raclopride binding Radioligand binding Rapamycin Raphe nucleus Rat Rat C6-glial cell line Rat P2Y, receptor Receptor subunit mRNAs Recombinant h5-HT,, and h5-HT,, receptor Recombinant human 5-HT,, receptor Release Remacemide hydrochloride Reoxygenation injury Retina Retinal ON bipolar cells Reverse transcriptase polymerase chain reaction Ritanserin RS 57639
51,513,665,999,
1483 779 1483 1755 1713 1539 499 1243 1641 499 429 1713 951 177 145 13 543 577 671
S s 15535 s-loop SB 206553 SB 242084 SCH 58261 SCH23390 Schizophrenia Sciatic constriction injury Secretion Seizures Self-stimulation Sensorimotor reactivity Sensory neurons L- Serine-O-phosphate (L-SOP) Serotonin (5-HT) see 5-HT Serotonin (5-HT),, receptors Sexual behaviour sFv antibody SH-SYSY neuroblastoma cells SHR rats Sigma sites Single channel recording Single motor unit Single-cell RT-PCR Slow-onset potentiation Small GTP-binding proteins Social interaction test
451 445 793 609 1327 101, 1589 779, 1665 1023 1783 345,609 1109 1511 1229, 1303 335 1733 769 63 125, 1771 483 51 63,649 1425 1641 1533 1771 601
Subject Index Sodium channel Sodium current Sodium-dependent
neurotransmitter
transport systems
L-SOP
Species comparisons Spider toxins Spinal cord SSRI Startle Staurosporine Stereotyped behavior Steroids Stoichiometry Stress Stretching-yawning Striatum Stroke Substance P Subtype-specific Subunit 8-b- Sulphophenyl) Sulpiride
101,325,467,
compounds theophylline
Sumatriptan Superior cervical ganglia Supersensitivity Sustained repetitive firing SV40T oncogene SYM 208 1 Sympathetic ganglia Synaptic density Synaptic depression Synaptic plasticity Synaptic transmission Synaptophysin
(8-SPT)
NP794,845,933,
1031 185 1741 845 513 185 1023,1561 467,475 1511 811 1115 1783 451 735 769 1447, 1455, 1571 1031 1009 1489 1611 169 1689 83,525,535,577 1747 1115 951 543 853 1009 1115 345 161,831,981, 1517 1477, 1555 973,1115
T Tail flicks Tardive dyskinesia Temperature A-9- Tetrahydrocannabinol Tetrodotoxin Theophylline Tianeptine Tolcapone Toxin pharmacology Toxins Transfection Transmitter release Transport kinetics TRE Triazoloquinazoline Trichloroethanol Trisomy Tryptophan Ts65Dn d- Tubocurarine
743 93 1725 1387 589,103l 1327 383 363 895 1489 63,803 1503, 1789 1167 1065 1157 941 1549 483 1549 1269
XXV
Subject Index Tumor necrosis factor Tyrosine hydroxylase
1157 75, 1065,1455
U 1167 1439
Uridine [3H]- Urocortin
V Vacuous chewing movements Vagal afferents Visual contrast Visual ON/OFF segregation Vogel test
w W~~100635 Weaver ataxia Wet dog shakes Wind up Withdrawal Withdrawal reflex
601,793,
93 489 135 135 1355
461,475,577 755 383 1425 101,151l 1425
X Xenopus oocyte
1611
Y YO-PRO dye uptake
1285
Z Zolpidem
1641
SUBJECT INDEX TO VOLUME 36
A Acetaldehyde Acetylcholine ACPD ( 1-aminocyclo-pentaneAdenine nucleotides Adenosine Adenosine A, receptor Adenosine A,, receptor Adenosine A, receptor Adenosine receptors Adenylyl cyclase ADP /3- Adrenergic receptor a2 Adrenergic receptor Afterhyperpolarization @ Agatoxin IVA Ageing Alcohol withdrawal Aldosterone Allosteric modulation Amino acid sequences Amino acids (S)-2- Amino-4-phosphonobutanoic
y-Aminobutyric
225 39, 241, 281, 295, 1119, 1733, 1783, 1789 1047,1533 1,3dicarboxylic acid) 1167, 1221 161, 169, 1127, 1149, 1157, 1201, 1253 161, 1211 1309,1319 1157 1141 713,1141,1157 1189 75 993 1653 865 973 1369 763 649 513 225 13,21, 153, 313, acid (L-AP4) 335, 845, 1517
acid (see GABA) 31 l- Aminocyclopropanecarboxylic acid (ACPC) 1393 AMPA-NMDA receptor interaction 335, 1489, 1503 AMPA receptor 1393 AMPA/kainate receptor desensitization 787, 1471 Amphetamine 735 Amygdala 281 Analgesia 1779 Anesthesia 941,981 Anoxia 1079 Antibodies 951, 1369 Anticonvulsant 475 Antidepressant 467 Antidepressant activity 177 Antioxidants 345,405 Antisense 389,439,601,609,793, 1071, 1089, 1355 Anxiety 707, 1369 Anxiolytic 1065 AP- 1 transcription factor 1065 AP-3 transcription factor 353 APNEA 811, 1023, 1149 Apoptosis 951 ARL 12495AA 1425 Arthritis 697 Associative olfactory task 1127, 1149, 1181, 1189, 1221, 1229, 1277, 1295 ATP 1253 ATP receptors 1269 ATP-activated channel 281 Atropine XIII
Subject Index
XIV
Autoradiography tram- Azetidine-2,4_dicarboxylic
acid (tADA)
217,217,779, 1243 261,1533
B Baclofen Bacterial expression Baculovirus expression system Bartters syndrome Basolateral amygdala Behaviour Benzodiazepines Benzodiazepine receptors 5-{3-[((2S)-l,4-Benzodioxan-2-ylme~yl)~no]propoxy}-1,3-benzodioxole Benzomorphan 6- Benzoylheteratisine Bicuculline BIMUl Bradykinin Bradykinin receptors Brain development Buspirone BW 723C86 BZD receptor (type 2)
1387 1377 21 755 1555 233,241,631 389,601,823, 1641 1641,1659 (MKC-242)
1733 51 1039 1653, 1659, 1705 697 1009 115 445 1089 233 1641
C CA1 Caffeine Calcium channel Calcium channel (P-type) Calcium channel blockers Calcium channels Calcium currents Calcium currents (presynaptic) Calcium mobilization Calcium permeability Calcium-dependent release Calcium/calmodulin-dependent CAMP CAMP-dependent protein kinase Cannabinoids Capsaicin Carbachol p Carboline 5- Carboxamidotryptamine Caspases Catecholamines Caudate nucleus Caudate-putamen L- CCG I CCK, receptor Cell death Cell permeabilization Cerebellar nuclei Cerebellum
protein kinase II
1533, 1539 1309 1796 405 865 353,405,865, 895, 1795 115, 195 185 125,429 1253 1253 1763 145, 153, 353,429,721, 933, 1201, 1631 209 1387 1417 1771 1771 83,535 1149 1783 577 779, 1589 1 1679 1295 1285 75 75,401,411,865
Subject Index CGMP CGP 37849 CGP 40116 CGP-3955 1 Chelerytrine chloride Chimeras Chinese hamster ovary cells (CHO cells) (JW)-2- Chloro-5-hydroxyphenylglycine (CHFG) 4 C3HPG m- Chlorophenylbiguanide Chlorpromazine Cholecystokin (CCK) receptors Cholecystokinin (CCK) Cholera toxin Choline uptake (high affinity) Cholinergic Cholinergic neurons Citalopram Cloning Clozapine CNQX Cobalt Cocaine Cochlea COMT inhibitor Concanavalin A Conditioned place preference u)- Conotoxin MVIIC @ Conotoxin GVIA CP-122 288 CP-93 129 S-4 CPG CR 2249 (4-amino-5-[4,4-dimethylcyclohexyl)amino]-5-oxopentanoic Craniofacial development CRF (corticotropin releasing factor) CRF, receptor CW, receptor Cultured dorsal root ganglion neurones Cyclic AMP (see CAMP) Cyclic AMP response element binding protein (CREB) Cyclooxygenase Cyclothiazide Cytochrome-c oxidase
xv 1393, 1405 31 1555 961 1047 1489 145, 153 1517 1533 665 665 389, 1679 389, 1679 1623 1741 281 1755 461,475 917 1689 1503 335 373,769 1269 363 1503 251 865 195 83,525 525 1047, 1533 acid) 1057 445 1439 1439 1439 195 1659 411 1009 335,1393, 1503 1665
D [%I dATPaS binding Daurisoline Deaminase Deliberate self harm Delta opioid receptor Dentate gyrus Depotentiation Deprenyl Desensitization
1243 107 169 439 1763 345,973 161, 1339 1455 1141,1303
Subject Index
XVI
Development Dialysis (2S,l’R,2’R,3’@-2-(2’,3’-
Dicarboxycyclopropyl)glycine Dihydropyridine
217 241 1517 1157 1047,1517 577,147l 917 39 1463
(DCG-IV)
(RS)-3,5- Dihydroxyphenylglycine (DHPG) 2,5- Dimethoxy-4-iodoamphetamine (DOI) Distribution DMPP DOM Dopamine Dopamine Dopamine Dopamine
251,787, (DA) agonists antagonists
Dopamine D, receptor Dopamine D, receptor Dopamine D, receptor Dopamine D, receptor Dopamine metabolism Dopamine receptors Dopamine release Dopaminergic neurones Dopaminergic supersensitivity Dorsal hippocampus Dorsal raphe nucleus Dorsal root ganglia Down Syndrome DPCPX DRG explants Drug Drug Drug Dura
discrimination reward screening mater
1115, 1455, 1471, 1571, 1679 373 1099 1099 93, 101,1679, 1689 93,769,779,787,999, 1689 787,999,1689 999 225 1689 1447 1653 1659 467 559,735 853, 1009 1549 1327 1755 373,147l 251 269 83,525
E Eating Ecto-apyrase Ecto-ATP diphosphohydrolase Ecto-ATPase Ecto-nucleotidase Ecto-phosphodiesterase Efficacy Electroconvulsive shock (ECS) Elevated plus-mare Elevated zero-maze Entorhinal cortex Environmental enrichment Ephedrine Epibatidine Epilepsy Epilepsy models Episodic ataxia Ethanol Eticlopride Excitotoxicity Exploratory behaviour
1725 1189 1189 1189 1189 1201 499 411 793, 1089 389 973 251 1417 1119 345,951,1393, 1405 1705 755 101, 1099 769, 1589 981 389
XVII
Subject Index
F 383 363 233,609 803 1755 1157 823 1285 1705 483 31 1201 411,1309,1779 467,475 917
Faecal pellets FDOPA Feeding d- Fenfluramine FK-506 Flavonoid Flunitrazepam Fluorescence imaging Fluoxetine Food deprivation Forced swimming test Forskolin c-fos Frontal cortex Functional expression
G G-proteins GABA GABA-glutamate interaction GABA-NMDA receptor interaction GABA, receptor GAB A, receptor channel GABA, receptor subunits GABAJbenzodiazepine receptor complex GABA, receptor Gabapentin GDP-j% Gene targeting Globus pallidus GluR5 GluR6 Glutamate Glutamate receptor Glutamatergic terminals Glycine Glycine, antagonists Glycine, partial agonists GR-127,935 GR113808 GR65630 Grooming (rat) GTP-YS [ssS]- GTPyS binding Guanine nucleotides Guinea pig
295,451,
1211, 1623,1747 941, 1387, 1789 1393 1405 63,823,941, 1377, 1405, 1611 1623, 1631 1377,1601, 1611, 1641 1071 1405 1369 1623 135 1309 853 853 305,401, 1517, 1571,1789 853 589 1057 1355 1355 83 671 665 1679 1623 451,499 1157 51,513,549,559, 1713
H Hair cell Hallucinogens Haloperidol HEK293 cells
1269 631, 1463 1689 1181
XVIII
Subject Index
Hemicholinium mustard Heteratisine Heterologous expression Hippocampal Hippocampal slice Hippocampus
1741 1039 569 1517 1057
systems
177,261,305,961, 31,319,345, 353,397,411,475,735, 823,831,951, 1039, 1201, 1339, 1393, 1405, 1477, 1517, 1533, 1539, 1549, 1705 115 Hoe 140 125 Homologous desensitization 1513 4C3 HPG 373, 383, 461,475, 489, 543, 549, 5- HT (5-hydroxytryptamine, serotonin) 569, 589, 621, 631,671, 681, 689, 713,721,735, 1697 475 5- HT autoreceptor 1713 5- HT autoreceptors 225 5- HT metabolism 1697 5- HT neuronal activity 419,489,543,577 5- HT receptors 803, 1221 5- HT release 373,461 5- HT reuptake inhibition 1725 5- HT syndrome 1079 5- HT-moduline 461,483 5- HT,, autoreceptor 483 5- HT,, autoreceptors midbrain 373,429,445,451,461,467,743, 1071, 5- HT,, receptor 1089, 1725, 1733 373,467,513,525,535, 1079 5- HT,, receptor 559 5- HT,,,,, autoreceptors 83,549 5-HT IB/lD receptor 513,525,535 5- HT,, receptor 535 5- HT,, receptor 631,793, 1471 5- HT, receptor 589 5- HT,, receptor 233,601 5- HT,, receptor 233,609,621,743 5- HT,, receptor 637.649,665 5- HT, receptor 671,681,689,697; 707,763 5- HT, receptor 713 5- HT, receptor 439,803 5- HT transporter 145,513,763,779, 1181 Human 419 Human genome 1433 Hydrocortisone 1733 8- Hydroxy-2-(di-n-propylamino)tetralin (8-OH-DPAT) 1571 No- Hydroxy-L-arginine 1659 6- Hydroxydopamine lesioning 649 5- Hydroxyindole 5- Hydroxytryptamine, 5- Hydroxytryptophan Hyoscyamine Hyperalgesia Hypoglycemia Hypotension Hypothalamus Hypothermia Hypoxia
see 5-HT accumulation
107,981,
483 281 1425 107 1779 1713 993 1327
XIX
Subject Index I IH
Immediate early genes Immortalized Immunocytochemistry Immunohistochemistry Immunophilin In situ hybridization Indomethacin Inflammation Input conductance Interleukins Intracellular calcium Intrastriatal injection Inverse agonism Inverse agonist Inward rectifier Ionomycin Ionophoresis Ionotropic glutamate receptor agonists Ischemia
721 1309 543 1079,1779 217, 1229, 1277 1755 217, 1277, 1309 1417 1295 169 1009 1747 1659 451 499 209 1763 489 1047 981,1031,1327,1796
K 1167 853, 1483, 1489, 1503 853, 1477 535,631 1141 1763 1763 1763
K562 erythroleukemia Kainate receptor Kainic acid Ketanserin Kinases KN62 KN92 KN93
L Learning Lewis rats Lidocaine Light/dark choice test Linopirdine Lisuride Lobeline Locomotor activity Long QT syndrome Long-term depression (LTD) Long-term memory Long-term potentiation (LTP) Loreclezole Loss of righting reflex Low Caz+/high Mg2+ LTP LY293558 LY294486 LY307452 LY354740 Lysergic-acid diethylamide
(LSD)
281,689,697,
1549, 1583 483 1031 793 1747 769 39 251,787, 1099 755 161,397,1517 697 345,823,961,973, 1339, 1533, 1539, 1549 1601 1099 1539 1539 1477 1477 1 1,933 713,147l
Subject Index
M 1747 1277 1319 845 1, 845, 1047, 1339, 1533 577 793 1269 601 735 735 217 217 961 281,689, 823, 1057, 1583 1549 1623, 1631 1689 981 1, 13, 21, 135, 145, 261, 265, 305, 313, 335,401, 589, 831, 845,933, 1047, 1339, 1511, 1517, 1533 577 Metergoline 325, 1665 Methamphetamine 941 Methohexital 313 @,!+a- Methyl-4-carboxyphenylglycine 313 (RS)-a- Methyl-4-phosphonophenylglycine 577 2- Methyl-5-HT 1561 N- Methyl-D-aspartate (NMDA) 1517 N- Methyl-D-aspartate (NMDA) receptor 1697 3,4- Methylenedioxymethamphetamine (MDMA) 1483 [sH]-(2S,4R)-4- Methylglutamate 853, 1483 4- Methylglutamate 763 Metoclopramide M-current Macrophage MAP kinase MAP4 MCPG mCPP MDL 100,907 Mechano-electrical transducer channel Medial amygdaloid nucleus Medial prefrontal cortex Median raphe nucleus Melanocortin-3 receptor Melanocortins Memantine Memory Mental retardation Mercury chloride Messenger RNA Metabolic stress Metabotropic glutamate (mGlu) receptors
mGluR, see metabotropic glutamate receptors mGluR receptor (group I) Mianserin 255,461,467,475,549,787, Microdialysis Microglia Mifepristone Migraine Mitochondria MK-801 Molecular modelling Monoamine oxidase B (MAO-B) Monocyte Monosynaptic IPSPs Morphine Morphine withdrawal Mossy fibre Motoneurone Mouse defense test battery (MDTB) MPP+ MPTP-induced parkinsonism Muscarine
1533 793 1295, 1393, 1405, 1455, 1697, 1733 1277, 1295 1433 83,525,569 1665 325,961 269 1455 1277 169 251 241 1477 313,721 793 993 363 1747
XXI
Subject Index Muscarinic receptor Muscimol Mutagenesis
N N lE- 115 neuroblastoma Naloxone NBQX Necrosis Neonatal Neuritogenesis Neuroblastoma Neurogenic inflammation Neuroleptics Neuromuscular transmission Neuronal differentiation Neuropathic pain Neuroprotection Neurotensin Neurotensin receptors NGlOS-15 cells NGF Nicotine Nicotinic acetylcholine receptor Nitric oxide Nitrobenzylthioinosine NMDA (N-methyl-o-aspartate) NMDA channels NMDA receptor NMDA receptor antagonists Nociception Nociceptor Non-NMDA receptors Noradrenaline NOS inhibitors Noxious stimulation Nucleoside transport Nucleus accumbens Nucleus tractus solitarius (NTS)
209,281,295,681 1387 637
649 1433 1503 1149 1327 811 811 83 1115, 1665 185 1755 1561 1796 93 1447 115 1319 1119, 1511, 1783 39,269, 1119 1393, 1405, 1417, 1571, 1583, 1589 1167 16,39, 161,265,397 319 831,951, 1057, 1517, 1561 241, 1355 743, 1047 1303 1503 75,993, 1057 1417 1425 1167 325, 1447 489
0 Obsessive-compulsive disorder Oestrogen 8- OH-DPAT Olfactory memory Oligonucleotides Ontogenesis Opioid receptors 6 Opioid receptor Opioids Optokinetic nystagmus Orbitofrontal cortex Osmotic mini-pump Oxygen radicals
483,577,
577 1433 1071, 1705 681 345 305 251 125, 1763 1109 135 577 1119 177
Subject Index
P Pl receptors P2 receptors P2X receptor P2X, receptor P2Y 1 receptor P2Y, receptor Pain Passive avoidance learning Patch-clamp electrophysiology PC12 cells PCP (phencyclidine) (-)- Penbutolol Pentobarbital Peptide Ca2+ channel blockers Pertussis toxin PET Pharmacological profiling Pharmacology Phenylglycine derivatives Phenylglycines Phenytoin pHook Phorbol ester Phosphatidylethanol Phosphatidylinositol phosphates Phospholipase C Phospholipase D Phosphorylation phOx antigen PK 11195 Plasticity Plus-maze Polyamine amides Polyamines Polymorphism Population spike Potassium channel Potentiation l- PP (1-(2-pyrimidinyl)-piperazine) Prefrontal cortex Preproenkephalin mRNA Preprotachykinin mRNA Presynaptic inhibition Proadifen Progesterone Propofol Prostaglandin E (EP) receptor Prostaglandin Ei Protein kinase Protein kinase A Protein kinase C Protein synthesis Pupillary response Purification Purinergic Purinergic receptors
1127 1221 1303 1285 1243 1181 281, 1009, 1425 961 1641 1319 1665 475 1611 195 1623 363 917 1796 933 13,265 1031 63 1631 295 1771 261, 1181, 1771 261,295, 305 411, 1377, 1631 63 1659 397, 1047 1355 185 185 439 1039 209 313,649, 1611 1089 589 325 325 845 1089 1433, 1783 941, 1611 1023 1023 295, 1377, 1631 1539 209, 1047 973 135 1211 1303 353, 1229, 1277 1127, 1269, 1277, 1181,
XXIII
Subject Index
107,865
Purkinje cell
Q
787
Quinelorane
R Rabbit brain synaptic membranes Raclopride binding Radioligand binding Rapamycin Raphe nucleus Rat Rat C6-glial cell line Rat P2Y, receptor Receptor subunit mRNAs Recombinant h5-HT,, and h5-HT,, receptor Recombinant human 5-HT,, receptor Release Remacemide hydrochloride Reoxygenation injury Retina Retinal ON bipolar cells Reverse transcriptase polymerase chain reaction Ritanserin RS 57639
51,513,665,999,
1483 779 1483 1755 1713 1539 499 1243 1641 499 429 1713 951 177 145 13 543 577 671
S s 15535 s-loop SB 206553 SB 242084 SCH 58261 SCH23390 Schizophrenia Sciatic constriction injury Secretion Seizures Self-stimulation Sensorimotor reactivity Sensory neurons L- Serine-O-phosphate (L-SOP) Serotonin (5-HT) see 5-HT Serotonin (5-HT),, receptors Sexual behaviour sFv antibody SH-SYSY neuroblastoma cells SHR rats Sigma sites Single channel recording Single motor unit Single-cell RT-PCR Slow-onset potentiation Small GTP-binding proteins Social interaction test
451 445 793 609 1327 101, 1589 779, 1665 1023 1783 345,609 1109 1511 1229, 1303 335 1733 769 63 125, 1771 483 51 63,649 1425 1641 1533 1771 601
Subject Index Sodium channel Sodium current Sodium-dependent
neurotransmitter
transport systems
L-SOP
Species comparisons Spider toxins Spinal cord SSRI Startle Staurosporine Stereotyped behavior Steroids Stoichiometry Stress Stretching-yawning Striatum Stroke Substance P Subtype-specific Subunit 8-b- Sulphophenyl) Sulpiride
101,325,467,
compounds theophylline
Sumatriptan Superior cervical ganglia Supersensitivity Sustained repetitive firing SV40T oncogene SYM 208 1 Sympathetic ganglia Synaptic density Synaptic depression Synaptic plasticity Synaptic transmission Synaptophysin
(8-SPT)
NP794,845,933,
1031 185 1741 845 513 185 1023,1561 467,475 1511 811 1115 1783 451 735 769 1447, 1455, 1571 1031 1009 1489 1611 169 1689 83,525,535,577 1747 1115 951 543 853 1009 1115 345 161,831,981, 1517 1477, 1555 973,1115
T Tail flicks Tardive dyskinesia Temperature A-9- Tetrahydrocannabinol Tetrodotoxin Theophylline Tianeptine Tolcapone Toxin pharmacology Toxins Transfection Transmitter release Transport kinetics TRE Triazoloquinazoline Trichloroethanol Trisomy Tryptophan Ts65Dn d- Tubocurarine
743 93 1725 1387 589,103l 1327 383 363 895 1489 63,803 1503, 1789 1167 1065 1157 941 1549 483 1549 1269
XXV
Subject Index Tumor necrosis factor Tyrosine hydroxylase
1157 75, 1065,1455
U 1167 1439
Uridine [3H]- Urocortin
V Vacuous chewing movements Vagal afferents Visual contrast Visual ON/OFF segregation Vogel test
w W~~100635 Weaver ataxia Wet dog shakes Wind up Withdrawal Withdrawal reflex
601,793,
93 489 135 135 1355
461,475,577 755 383 1425 101,151l 1425
X Xenopus oocyte
1611
Y YO-PRO dye uptake
1285
Z Zolpidem
1641