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T89. Personality psychopathology five and P300 in young healthy adults
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Abstracts / Clinical Neurophysiology 129 (2018) e1–e65
T88. Optimizing lower limb Somatosensory Evoked Potentials (SEPs) with additional derivations—Sahawat Tantikittichaikul *, Ernest Hoffman (USA) ⇑
Presenting author.
Introduction: SEPs recorded over the scalp serve as surrogate markers of dorsal column proprioceptive pathway integrity during surgery. Changes in SEP amplitude and/or latency meeting ‘‘alarm criteria” can indicate neural injury and prompt the surgical team to take action. Alarm criteria (e.g. 50% drop in amplitude) lose specificity when SEP measurement variability is high (e.g. P25%). Lower limb scalp SEPs has vary dipole vectors between individuals. Standard recording electrode derivations of SEPs have been shown to be suboptimal when compared to a derivation individually optimized for each patient. Methods: Scalp lower limb SEPs were monitored from a consecutive sample of 51 patients during non-emergent procedures at Mayo Clinic Rochester. Two additional scalp electrodes at Cz and Pz were setup beside the standard scalp electrodes (CPz, Fz, CPi and CPc). Two standard derivations (CPz-Fz and CPi-CPc) and five expanded derivations (CPz-CPc, Cz-CPc, Pz-CPc, CPz-CPi and Pz-Fz) were recorded. P38 amplitudes were measured for all derivations; the derivation with the lowest coefficient of variation (CV) and highest amplitude from each group (standard vs. expanded montage) were determined. Results: The P38 with highest amplitude and lowest CV were found in the expanded montage in 78 (76%) and 71 (70%) out of 102 limbs from 51 patients. The expanded montage significantly lowered the minimum CV by 1.75% (P < 0.0001, linear regression) and increased the maximal amplitude by 0.13 lV (P < 0.0001, linear regression) as compared to the standard montage. The CPz-CPc was the most frequent derivation with lowest CV and highest amplitude among all seven derivations. Conclusion: The effort to implement an expanded scalp montage should be balanced with the potential improvements, which by our data, are only incremental. An expanded scalp montage may be highest yield in patients where recordings from a conventional montage are of poor quality.
no history of neurological and/or psychiatric diseases, with clinical EEG within the normal limits for the age. The EEG was performed with 62 gold electrodes according to the international system 10– 20 during the execution of the visual AX-CPT. The task consisted in the presentation of letters J, K S and T on a monitor 60 cm away from the view of the participants. The following instruction was given for the task: ‘‘you will see some letters appear on this screen. You must press button number 1 every time the T appears after S ”. The ERPs were analyzed under an oddball paradigm of three stimuli, where the infrequent stimulus was the letter T (target stimulus) and the distractor was the letters J, S or K presented after the S. The analysis window (time-windows) was 100 to 500 ms and the analysis derivations were FZ and PZ. Results: In the FZ derivation, the subcomponent P3a was identified at 360 ms before the distractor stimulus, with an amplitude of 1.8 lV, and frontal topography. In PZ the subcomponent P3b was observed at 302 ms before the infrequent stimulus, with an amplitude of 0.5 lV and subsequent topographic distribution. The dimensions of the distractor stimulus were associated with the personality traits. In women, the increase in the social Introversion trait was related to a lower amplitude (r = 0.470) while the lack of control trait was greater (r = 0.450). In men, the increase in the scores of the aggressiveness trait was directly associated with the increase in the amplitude of the distractor stimulus (r = 0.413). Conclusion: In women, personality traits that involved inhibition were associated with processes of inhibitory control at the cognitive and behavioral levels, whereas in men, traits that reflect hyperactivation or hypervigilance such as aggression were associated with the use of more neuronal resources. doi:10.1016/j.clinph.2018.04.090
T90. Pilot study to compare the P300 component in resident physicians with acute sleep deprivation after a night shift and non-exposed controls—Alexis I. Cervantes Gonzalez *, Gilberto Angel Maldonado-Torres, Cecilia Alejandra Carranza-Alva, Armando Torres-Gómez, Paul Shkurovich Bialik (Mexico) ⇑
Presenting author.
doi:10.1016/j.clinph.2018.04.089
T89. Personality psychopathology five and P300 in young healthy adults—Karina N. Velasco *, Dora E. Granados, Gabriela Romero Esquiliano (Mexico) ⇑
Presenting author.
Introduction: Personality traits are dispositions to act, think or feel. The Personality Psychopathology Five model includes the following traits to describe personality: Aggressiveness, Psychoticism, Lack of Control, Neuroticism and Introversion. In P300 associations have been observed between amplitude and personality traits: in the neuroticism and psychoticism traits less amplitude is reported while in the extroversion, openness, kindness and responsibility traits the amplitude is greater. In P300, two subcomponents, P3a and P3b, have been described. The Continuous Performance Test is a series of neuropsychological assessment paradigms that have been used to favor P300. The aim of this research was to describe the relationship between Personality Psychopathology Five and P300 in healthy young adults. Methods: The sample was 60 healthy adults with an average age of 21 years one month, S.D. ± 2 years five months, 30 men and 30 women with an average Intellectual Coefficient (102, S.D. ± 8), with
Introduction: Medical residency in Mexico as in many other countries is a stressful experience. Sleep deprivation among other factors to which the resident is exposed are associated with various cognitive and emotional alterations. The impact of prolonged awake in the lives of residents is already well described, the present study aims to demonstrate with an objective neurophysiological parameter (P300) cognitive alterations, particularly in selective attention, presented by resident physicians after a night shift comparing them against themselves after a night of rest and against a control group not exposed to acute or chronic sleep restriction. Methods: An observational study was carried out with 40 participant cohorts and controls, 20 for the control group without sleep restriction who underwent P300 before and after a night of physiological sleep; and 20 resident physicians of different specialties at the ABC Medical Center in Mexico city, in whom P300 were performed before and after a night shift, to analyze changes in latency and amplitude associated with acute sleep deprivation. Results: The mean age for residents was 29.65 ± 2.85 years and for the control group 30.30 ± 2.95 years. The mean latency for residents was 302.04 ± 23.86 ms vs 292.11 ± 36.35 ms in controls (p0.272); for amplitude was 5.52 ± 2.97 lV in the residents group vs 6.50 ± 4.02 lV in controls (p 0.161). When we compared latency and amplitude among the residents before and after a night shift, a mean latency of 300.63 ± 23.16 ms was found in the pre night shift group vs 303.74 ±
Abstracts / Clinical Neurophysiology 129 (2018) e1–e65
T88. Optimizing lower limb Somatosensory Evoked Potentials (SEPs) with additional derivations—Sahawat Tantikittichaikul *, Ernest Hoffman (USA) ⇑
Presenting author.
Introduction: SEPs recorded over the scalp serve as surrogate markers of dorsal column proprioceptive pathway integrity during surgery. Changes in SEP amplitude and/or latency meeting ‘‘alarm criteria” can indicate neural injury and prompt the surgical team to take action. Alarm criteria (e.g. 50% drop in amplitude) lose specificity when SEP measurement variability is high (e.g. P25%). Lower limb scalp SEPs has vary dipole vectors between individuals. Standard recording electrode derivations of SEPs have been shown to be suboptimal when compared to a derivation individually optimized for each patient. Methods: Scalp lower limb SEPs were monitored from a consecutive sample of 51 patients during non-emergent procedures at Mayo Clinic Rochester. Two additional scalp electrodes at Cz and Pz were setup beside the standard scalp electrodes (CPz, Fz, CPi and CPc). Two standard derivations (CPz-Fz and CPi-CPc) and five expanded derivations (CPz-CPc, Cz-CPc, Pz-CPc, CPz-CPi and Pz-Fz) were recorded. P38 amplitudes were measured for all derivations; the derivation with the lowest coefficient of variation (CV) and highest amplitude from each group (standard vs. expanded montage) were determined. Results: The P38 with highest amplitude and lowest CV were found in the expanded montage in 78 (76%) and 71 (70%) out of 102 limbs from 51 patients. The expanded montage significantly lowered the minimum CV by 1.75% (P < 0.0001, linear regression) and increased the maximal amplitude by 0.13 lV (P < 0.0001, linear regression) as compared to the standard montage. The CPz-CPc was the most frequent derivation with lowest CV and highest amplitude among all seven derivations. Conclusion: The effort to implement an expanded scalp montage should be balanced with the potential improvements, which by our data, are only incremental. An expanded scalp montage may be highest yield in patients where recordings from a conventional montage are of poor quality.
no history of neurological and/or psychiatric diseases, with clinical EEG within the normal limits for the age. The EEG was performed with 62 gold electrodes according to the international system 10– 20 during the execution of the visual AX-CPT. The task consisted in the presentation of letters J, K S and T on a monitor 60 cm away from the view of the participants. The following instruction was given for the task: ‘‘you will see some letters appear on this screen. You must press button number 1 every time the T appears after S ”. The ERPs were analyzed under an oddball paradigm of three stimuli, where the infrequent stimulus was the letter T (target stimulus) and the distractor was the letters J, S or K presented after the S. The analysis window (time-windows) was 100 to 500 ms and the analysis derivations were FZ and PZ. Results: In the FZ derivation, the subcomponent P3a was identified at 360 ms before the distractor stimulus, with an amplitude of 1.8 lV, and frontal topography. In PZ the subcomponent P3b was observed at 302 ms before the infrequent stimulus, with an amplitude of 0.5 lV and subsequent topographic distribution. The dimensions of the distractor stimulus were associated with the personality traits. In women, the increase in the social Introversion trait was related to a lower amplitude (r = 0.470) while the lack of control trait was greater (r = 0.450). In men, the increase in the scores of the aggressiveness trait was directly associated with the increase in the amplitude of the distractor stimulus (r = 0.413). Conclusion: In women, personality traits that involved inhibition were associated with processes of inhibitory control at the cognitive and behavioral levels, whereas in men, traits that reflect hyperactivation or hypervigilance such as aggression were associated with the use of more neuronal resources. doi:10.1016/j.clinph.2018.04.090
T90. Pilot study to compare the P300 component in resident physicians with acute sleep deprivation after a night shift and non-exposed controls—Alexis I. Cervantes Gonzalez *, Gilberto Angel Maldonado-Torres, Cecilia Alejandra Carranza-Alva, Armando Torres-Gómez, Paul Shkurovich Bialik (Mexico) ⇑
Presenting author.
doi:10.1016/j.clinph.2018.04.089
T89. Personality psychopathology five and P300 in young healthy adults—Karina N. Velasco *, Dora E. Granados, Gabriela Romero Esquiliano (Mexico) ⇑
Presenting author.
Introduction: Personality traits are dispositions to act, think or feel. The Personality Psychopathology Five model includes the following traits to describe personality: Aggressiveness, Psychoticism, Lack of Control, Neuroticism and Introversion. In P300 associations have been observed between amplitude and personality traits: in the neuroticism and psychoticism traits less amplitude is reported while in the extroversion, openness, kindness and responsibility traits the amplitude is greater. In P300, two subcomponents, P3a and P3b, have been described. The Continuous Performance Test is a series of neuropsychological assessment paradigms that have been used to favor P300. The aim of this research was to describe the relationship between Personality Psychopathology Five and P300 in healthy young adults. Methods: The sample was 60 healthy adults with an average age of 21 years one month, S.D. ± 2 years five months, 30 men and 30 women with an average Intellectual Coefficient (102, S.D. ± 8), with
Introduction: Medical residency in Mexico as in many other countries is a stressful experience. Sleep deprivation among other factors to which the resident is exposed are associated with various cognitive and emotional alterations. The impact of prolonged awake in the lives of residents is already well described, the present study aims to demonstrate with an objective neurophysiological parameter (P300) cognitive alterations, particularly in selective attention, presented by resident physicians after a night shift comparing them against themselves after a night of rest and against a control group not exposed to acute or chronic sleep restriction. Methods: An observational study was carried out with 40 participant cohorts and controls, 20 for the control group without sleep restriction who underwent P300 before and after a night of physiological sleep; and 20 resident physicians of different specialties at the ABC Medical Center in Mexico city, in whom P300 were performed before and after a night shift, to analyze changes in latency and amplitude associated with acute sleep deprivation. Results: The mean age for residents was 29.65 ± 2.85 years and for the control group 30.30 ± 2.95 years. The mean latency for residents was 302.04 ± 23.86 ms vs 292.11 ± 36.35 ms in controls (p0.272); for amplitude was 5.52 ± 2.97 lV in the residents group vs 6.50 ± 4.02 lV in controls (p 0.161). When we compared latency and amplitude among the residents before and after a night shift, a mean latency of 300.63 ± 23.16 ms was found in the pre night shift group vs 303.74 ±