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214: Prevalence of metabolic syndrome among cardiology patients in Batumi, Georgia
Journal of Clinical Lipidology, Vol 2, No 5S, October 2008
213 THE PREVALENCE OF THE METABOLIC SYNDROME IN TYPE 2 DIABETIC PATIENTS IN TWO CARIBBEAN ISLANDS C. Ezenwaka1, E. Nwagbara2, D. Seales1, F. Okali2, S. Hussaini2, B Raja2. 1Unit of Pathology & Microbiology, Faculty of Medical Sciences, The University of the West Indies, St Augustine, Trinidad - Tobago, 2Tobago Regional Health Authority, Tobago, Trinidad - Tobago Objective: To determine the prevalence of the metabolic syndrome and its components in type 2 diabetic patients at the primary care settings in Tobago and Trinidad. Methods: 413 (166 Tobago, 247 Trinidad) type 2 diabetic patients visiting primary care clinics were studied. Blood pressure and anthropometric parameters (BMI and waist circumference) were measured while overnight fasting blood samples were taken for plasma glucose and serum triglycerides, total cholesterol, LDL- and HDL-cholesterol. The metabolic syndrome was defined using the new International Diabetes Federation definition. Results: The duration of diabetes (9.4 ± 0.5 vs. 11.1 ± 0.7 yr), medications, generalized (31.7 vs. 38.8%) and central (78.5 vs. 83.7%) obesity were similar (p > 0.05) in the patients from both islands. However, in comparison with patients in Tobago, diabetic patients in Trinidad, irrespective of gender, had significantly higher prevalence of critical components of the metabolic syndrome such as raised blood pressure, raised triglycerides and reduced high-density lipoprotein-cholesterol (all, p < 0.001). Thus, while more patients in Trinidad were diagnosed with metabolic syndrome based on three or four components (22 vs. 5%, p < 0.001), more patients in Tobago were diagnosed based on two components (48 vs. 22%, p < 0.001). Conclusions: The overall prevalence rate of the metabolic syndrome in the diabetic population studied is 69% while the aggregation of the components is higher in more developed and industrialized city of Trinidad. Funding: The University of the West Indies provided financial support 214 PREVALENCE OF METABOLIC SYNDROME AMONG CARDIOLOGY PATIENTS IN BATUMI, GEORGIA
B. Gelaye1, N Dolidze2, D Enquobahrie1,3, G Chapidze2, A Fitzpatrick1, M Williams1. 1 University of Washington, Seattle, WA, USA, 2 Emergency Cardiology Center, Tbilisi, Georgia, 3 Harvard University, Boston, MA, USA Objective: Metabolic syndrome(MetS) is associated with increased morbidity and mortality from cardiovascular diseases. In this study, we investigated the prevalence of MetS and risk factors associated with Mets among cardiology patients in Rep of Georgia. Methods: This cross-sectional study was conducted among 281 cardiology patients in Batumi, Georgia. In-person interviews, clinical exams and laboratory studies were conducted to characterize MetS and risk factors associated with Mets. MetS was defined as the presence of three or more of the following, using the Adult Treatment Panel III (ATPIII) criteria:(1)elevated blood pressure(BP), (2)abdominal obesity, (3) reduced HDL, (4)elevated triglyceride, and (5)elevated fasting glucose. Results: Overall the prevalence of the MetS in the study population was 68.6%. Only 4% of study participants had none of the metabolic abnormalities that are part of the Mets. Women (71.4%) had higher percentage of MetS compared with men (64.3%). The three most prevalent metabolic abnormalities in men were elevated BP, abdominal obesity and elevated triglyceride. Among women, abdominal obesity, elevated BP and reduced HDL were the most common abnormalities. Age and work-related manual labor were marginally associated with MetS among women participants. No significant difference in socio-demographic and lifestyle characteristics was detected between patients with Mets and without Mets. Conclusions: MetS and its components are highly prevalent among Georgian cardiology patients. These findings highlight the need for promoting greater management of metabolic disorders among cardiology patients. Funding: none
215 DETERMINANTS OF THE METABOLIC SYNDROME IN A MEDITERRANEAN POPULATION: LARGE WAIST CIRCUMFERENCE IS THE BEST PREDICTOR OF THE METABOLIC SYNDROME G. Mombelli1, A.M. Zanaboni2, S. Gaito2,
S99
213 THE PREVALENCE OF THE METABOLIC SYNDROME IN TYPE 2 DIABETIC PATIENTS IN TWO CARIBBEAN ISLANDS C. Ezenwaka1, E. Nwagbara2, D. Seales1, F. Okali2, S. Hussaini2, B Raja2. 1Unit of Pathology & Microbiology, Faculty of Medical Sciences, The University of the West Indies, St Augustine, Trinidad - Tobago, 2Tobago Regional Health Authority, Tobago, Trinidad - Tobago Objective: To determine the prevalence of the metabolic syndrome and its components in type 2 diabetic patients at the primary care settings in Tobago and Trinidad. Methods: 413 (166 Tobago, 247 Trinidad) type 2 diabetic patients visiting primary care clinics were studied. Blood pressure and anthropometric parameters (BMI and waist circumference) were measured while overnight fasting blood samples were taken for plasma glucose and serum triglycerides, total cholesterol, LDL- and HDL-cholesterol. The metabolic syndrome was defined using the new International Diabetes Federation definition. Results: The duration of diabetes (9.4 ± 0.5 vs. 11.1 ± 0.7 yr), medications, generalized (31.7 vs. 38.8%) and central (78.5 vs. 83.7%) obesity were similar (p > 0.05) in the patients from both islands. However, in comparison with patients in Tobago, diabetic patients in Trinidad, irrespective of gender, had significantly higher prevalence of critical components of the metabolic syndrome such as raised blood pressure, raised triglycerides and reduced high-density lipoprotein-cholesterol (all, p < 0.001). Thus, while more patients in Trinidad were diagnosed with metabolic syndrome based on three or four components (22 vs. 5%, p < 0.001), more patients in Tobago were diagnosed based on two components (48 vs. 22%, p < 0.001). Conclusions: The overall prevalence rate of the metabolic syndrome in the diabetic population studied is 69% while the aggregation of the components is higher in more developed and industrialized city of Trinidad. Funding: The University of the West Indies provided financial support 214 PREVALENCE OF METABOLIC SYNDROME AMONG CARDIOLOGY PATIENTS IN BATUMI, GEORGIA
B. Gelaye1, N Dolidze2, D Enquobahrie1,3, G Chapidze2, A Fitzpatrick1, M Williams1. 1 University of Washington, Seattle, WA, USA, 2 Emergency Cardiology Center, Tbilisi, Georgia, 3 Harvard University, Boston, MA, USA Objective: Metabolic syndrome(MetS) is associated with increased morbidity and mortality from cardiovascular diseases. In this study, we investigated the prevalence of MetS and risk factors associated with Mets among cardiology patients in Rep of Georgia. Methods: This cross-sectional study was conducted among 281 cardiology patients in Batumi, Georgia. In-person interviews, clinical exams and laboratory studies were conducted to characterize MetS and risk factors associated with Mets. MetS was defined as the presence of three or more of the following, using the Adult Treatment Panel III (ATPIII) criteria:(1)elevated blood pressure(BP), (2)abdominal obesity, (3) reduced HDL, (4)elevated triglyceride, and (5)elevated fasting glucose. Results: Overall the prevalence of the MetS in the study population was 68.6%. Only 4% of study participants had none of the metabolic abnormalities that are part of the Mets. Women (71.4%) had higher percentage of MetS compared with men (64.3%). The three most prevalent metabolic abnormalities in men were elevated BP, abdominal obesity and elevated triglyceride. Among women, abdominal obesity, elevated BP and reduced HDL were the most common abnormalities. Age and work-related manual labor were marginally associated with MetS among women participants. No significant difference in socio-demographic and lifestyle characteristics was detected between patients with Mets and without Mets. Conclusions: MetS and its components are highly prevalent among Georgian cardiology patients. These findings highlight the need for promoting greater management of metabolic disorders among cardiology patients. Funding: none
215 DETERMINANTS OF THE METABOLIC SYNDROME IN A MEDITERRANEAN POPULATION: LARGE WAIST CIRCUMFERENCE IS THE BEST PREDICTOR OF THE METABOLIC SYNDROME G. Mombelli1, A.M. Zanaboni2, S. Gaito2,
S99