4672030 Test kit for the determination of activated thromboplastin time (PTT) with increased sensitivity to heparin

4672030 Test kit for the determination of activated thromboplastin time (PTT) with increased sensitivity to heparin

397 PATENT ABSTRACTS to splenocyte-donating mice. Also provided is a method for the biochemical purification of cytoplasmic antigen of a pathogenic C...

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397

PATENT ABSTRACTS to splenocyte-donating mice. Also provided is a method for the biochemical purification of cytoplasmic antigen of a pathogenic Candida species used for the preparation of monoclonal and monospecific, polyclonal antisera thereto. + RE

4670384 DIAGNOSTIC REAGENT FOR SWINE TRICHINOSIS Howard R Gamble, Kenneth D Murrell assigned to The United States of America as represented by the Secretary of Agriculture A hybrid cell formed by the fusion of a mouse spleen cell with a mouse myeloma cell secretes an lgM class antibody. The antibody is useful as a preparative reagent in the isolation of three proteins, molecular weights 45,000, 49,000 and 53,000, from the parasite Trichinella spiralis and is also useful as a direct diagnostic reagent is a competitive serodiagnostic test.

4670386 CANCER TESTS USING TUMOR ANTIGEN GENERATED LYMPHOKINES AND COMPOSITIONS Stephen Sugaar The present invention provides strongly antigenic tumor-specific substances (also cellular material containing said strongly antigenic tumor-specific substances) prepared by radiofrequency or microwave electromagnetic radiation, acting on cancer tissue or cancer cells of known pathohistologic character. Said substances and also cellular material containing said substances are characterized by such sensitizing antigenic qualities that when they are contacted with a composition of naturally cancer-sensitized lymphocytes taken from a host having pathohistologically related cancer, then said lymphocytes produce and exude lymphokine. The invention further provides diagnostic tests for cancer and compositions which contain or utilize said strongly-antigenic cancer-specific substances.

4670394 ISOLATION AND CULTURE OF ADRENAL MEDULLARY ENDOTHELIAL CELLS PRODUCING BLOOD CLOTTING FACTOR VIII:C Harvey B Pollard, Richar Ornberg, Dipak Banerjee, Moussa Youdim, Peter Lelkes, Eli Heldman assigned to The United States of America as represented by the Secretary of the Department of Health and Human Services The present invention discloses a new line of endothelial cell of adrenal medullary origin capable of producing blood clotting Factor VIII:C. A method of isolating and culturing said cell line has also been disclosed. Factor VIII:C is useful in treating hemophilia.

4672030 TEST KIT FOR THE DETERMINATION OF ACTIVATED THROMBOPLASTIN TIME (PTT) WITH INCREASED SENSITIVITY TO HEPARIN Pete Witt, D 7844 Neuenburg, Federal Republic Of Germany Partial thromboplastin time (PTT) is determined for monitoring and controlling heparin therapy with a test kit having increased sensitivity to heparin. Increased sensitivity is obtained by including with reagents in the test kit an organic sulfuric acid or salt thereof such as dodecylbenzenesulfuric acid£13 sodium salt and/or an organic sulfuric acid ester or salt thereof such as +PG,2 sodium laurylsulfate. + RE 4672053 IMMUNOAFFINITY PURIFICATION OF PHYTOLACCIN PROTEINS AND T H E I R U S E IN T R E A T I N G H E R P E S S I M P L E X V I R U S T Y P E II Tom G Obrig Antiviral proteins phytolaccinl and phytolaccin2 were isolated from the higher plant Phytolaccin americana using the technique of