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4874613 Taste concealing pharmaceutical dosage unit
New Patents
Budapest, Hungary assigned to EGIS Gyogyszergyar The invention relates to pharmaceutical compositions having analgesic and/or antiinflammatory effect comprising as active ingredient 2, 4-diamino-5-(3 4-dimethoxybenzyl)-pyrimidine or a pharmaceutically acceptable acid addition salt thereof. The pharmaceutical compositions of the present invention exhibit the desired analgesic and antiinflammatory effect without causing undesired ulcerogenic side-effects.
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4874614 PHARMACEUTICAL TABLETING METHOD Wallace Becker assigned to Abbott Laboratories A method of preventing the fracture of coated drug granules during the compression of the granules into a commercially acceptable tablet matrix is disclosed. The method involves incorporating into the matrix, along with the granules, from about 10% to about 50% by weight microcrystalline cellulose.
4873261
4874750
PHARMACEUTICAL COMPOSITION FOR TREATING ULCERATIVE LARGE INTESTINAL DISEASE
PHARMACEUTICAL COMPOSITION CONTAINING A DERIVATIVE OF PARAAMINOBENZOIC ACID AS AN ACTIVE INGREDIENT
Wasei Miyazaki, Yasuhiko Inoue, Tokushima, Japan assigned to Otsuka Pharmaceutical Co Ltd A method for treating ulcerative large intestinal diseases with a pharmcautical composition containing, as the active ingredient, a sesquiterpene compound or a salt thereof.
4874613 TASTE CONCEALING PHARMACEUTICAL DOSAGE UNIT Charles Hsiao assigned to Baker Cummins Pharmaceuticals Inc A pharmaceutical dosage unit suitable for masking the unpleasant taste of orally administered pharmaceutical agents and which facilitates swallowing comprises a plurality of subdosage units disposed within a container. Each subdosage unit is a pellet with an inner core coated with an active pharmaceutical agent, a first layer surrounding the core comprising a biologically inert excipient or filler, and a second layer surrounding the first layer comprising a mixture of a cationic copolymeric acrylate resin and a basic compound. The container of the dosage unit may be orally ingestible in itself, such as an openable gelatin capsule, or may be a frangible packet which must be opened in order to orally administer the subdosage pellets to a patient.
Chikao Yoshikumi, Yoshio Ohmura, Fumio Hirose, Masanori Ikuzawa, Kenichi Matsunaga, Takayoshi Fujii, Minoru Ohhara, Takao Ando, Kunitachi, Japan assigned to Kureha Kagaku Kogyo Kabushiki Kaisha Disclosed is a pharmaceutical composition containing an aminobenzoic acid derivative as an active ingredient represented by the following general formula: See Patent for Chemical Structure wherein I R donotes one member selected from the group consisting of the residual groups formed by removing OH at l(alpha) or l(beta) position from arabinose, glucose, galactose and mannose, or a pharmaceutically acceptable salt thereof.
4874756 BENZODIPYRROLES, PROCESSES FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM Alfre Mertens, Saal Wolfgang vonder, Herbert Berger, Bernd Muller-Beckmann, Klaus Strein, Schriesheim, Federal Republic Of Germany assigned to Boehringer Mannheim GmbH The present invention provides compounds of the general formula See Patent for Chemical
Budapest, Hungary assigned to EGIS Gyogyszergyar The invention relates to pharmaceutical compositions having analgesic and/or antiinflammatory effect comprising as active ingredient 2, 4-diamino-5-(3 4-dimethoxybenzyl)-pyrimidine or a pharmaceutically acceptable acid addition salt thereof. The pharmaceutical compositions of the present invention exhibit the desired analgesic and antiinflammatory effect without causing undesired ulcerogenic side-effects.
xxi
4874614 PHARMACEUTICAL TABLETING METHOD Wallace Becker assigned to Abbott Laboratories A method of preventing the fracture of coated drug granules during the compression of the granules into a commercially acceptable tablet matrix is disclosed. The method involves incorporating into the matrix, along with the granules, from about 10% to about 50% by weight microcrystalline cellulose.
4873261
4874750
PHARMACEUTICAL COMPOSITION FOR TREATING ULCERATIVE LARGE INTESTINAL DISEASE
PHARMACEUTICAL COMPOSITION CONTAINING A DERIVATIVE OF PARAAMINOBENZOIC ACID AS AN ACTIVE INGREDIENT
Wasei Miyazaki, Yasuhiko Inoue, Tokushima, Japan assigned to Otsuka Pharmaceutical Co Ltd A method for treating ulcerative large intestinal diseases with a pharmcautical composition containing, as the active ingredient, a sesquiterpene compound or a salt thereof.
4874613 TASTE CONCEALING PHARMACEUTICAL DOSAGE UNIT Charles Hsiao assigned to Baker Cummins Pharmaceuticals Inc A pharmaceutical dosage unit suitable for masking the unpleasant taste of orally administered pharmaceutical agents and which facilitates swallowing comprises a plurality of subdosage units disposed within a container. Each subdosage unit is a pellet with an inner core coated with an active pharmaceutical agent, a first layer surrounding the core comprising a biologically inert excipient or filler, and a second layer surrounding the first layer comprising a mixture of a cationic copolymeric acrylate resin and a basic compound. The container of the dosage unit may be orally ingestible in itself, such as an openable gelatin capsule, or may be a frangible packet which must be opened in order to orally administer the subdosage pellets to a patient.
Chikao Yoshikumi, Yoshio Ohmura, Fumio Hirose, Masanori Ikuzawa, Kenichi Matsunaga, Takayoshi Fujii, Minoru Ohhara, Takao Ando, Kunitachi, Japan assigned to Kureha Kagaku Kogyo Kabushiki Kaisha Disclosed is a pharmaceutical composition containing an aminobenzoic acid derivative as an active ingredient represented by the following general formula: See Patent for Chemical Structure wherein I R donotes one member selected from the group consisting of the residual groups formed by removing OH at l(alpha) or l(beta) position from arabinose, glucose, galactose and mannose, or a pharmaceutically acceptable salt thereof.
4874756 BENZODIPYRROLES, PROCESSES FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM Alfre Mertens, Saal Wolfgang vonder, Herbert Berger, Bernd Muller-Beckmann, Klaus Strein, Schriesheim, Federal Republic Of Germany assigned to Boehringer Mannheim GmbH The present invention provides compounds of the general formula See Patent for Chemical