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5026649 Apparatus for growing tissue cultures in vitro
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PATENT ABSTRACTS
A process for culturing bacteria is disclosed in which is utilized as a bacterial nutrition a serum byproduced upon treatment of a natural rubber latex. The serum has an ample supply, a low cost, a stable quality and a sufficient activity over a wide variety of bacteria, thus contributing to accelerative growth for aerobic and anaerobic bacteria.
5026649
the membrane and disbursed into the fluid medium along the length of the membrane.
5026840 PHOTOCHEMICAL NUCLEIC ACID-LABELING REAGENT HAVING A POLYALKLAMINE SPACER
APPARATUS FOR GROWING T I S S U E C U L T U R E S IN V I T R O
Nanibhushan Dattagupta. James P Albarella assigned to Molecular Diagnostics Inc
Georg Lyman, Gregory Mathus. David Root assigned to Costar Corporation
A photochemical nucleic acid-labeling reagent of the form ula See PatentJor Chemical Structure wherein Q is a photoreactive residue of a nucleic acid-binding ligand; L is a detectable label residue; R is hydrogen, CI to C7-alkyl, aryl, hydroxy, or C 1 to CT-alkoxy; x is an integer from 2 through 7, and Y is an integer from 3 through 10: wherein R and x, respectively, can be the same or different each time they appear in the formula. The reagent is useful in the highly cffclent labeling of nucleic acids for the purpose of detection in hybridization assays.
Apparatus for growing tissue cultures in vitro, which permits a concentration gradient of nutrients to develop through a permeable membrane to which a sample of tissue is attached. The permeable membrane is attached to the bottom end of a tubular support that in turn hangs by a flange connected to its upper end on the top of a well containing the nutrients. Typically, the well is part of a tissue culture cluster dish. The flange of the support positions the support and membrane centrally in the well so as to avoid capillary action in the space between the well and support. The configuration of the support and its cooperation with the lid of the cluster dish also prevents the support and membrane from floating in the nutrient solution in the well. Openings in the support provide access for a pipette to add and withdraw fluid from the space between the well and membrane support and from the space below the membrane.
5026650 HORIZONTALLY ROTATED CELL CULTURE SYSTEM WITH A COAXIAL TUBULAR OXYGENATOR Ray P Schwarz, David A Wolf. Tinh T Trinh assigned to The United States of Amercia as represented by the Administrator of the National Aeronautics and Space Administration A bio-reactor system where cell growth microcarrier beads are suspended in a zero head space fluid medium by rotation about a horizontal axis and where the fluid is continuously oxygenated from a tubular membrane which rotates on a shaft together with rotation of the culture vessel. The oxygen is continuously throughput through
5028398 DEVICE FOR PROVIDING A CONTINUOUS BIOLOGICAL DECOMPOSITION OF MINERALS AND CONCENTRATES THEREOF Rolf Hallberg, UIf Edvardsson, S 135 55 Tyres Sweded A lying rotatable drum for continuous biological decomposition which includes at least one transversal partition for dividing the container interior into chambers. The partition has opening to transmit liquid between the chambers. Guide means are also provided.
5028524 ASSAY FOR ANTI-PRE-S ANTIBODY Yukio Fujisawa, Osamu Nishimura, Yasuaki ltoh, Kobe. Japan assigned to Takeda Chemical Industries Lid Assays for an anti-pre-S antibody in a human serum by an enzyme immunoassay in which a
PATENT ABSTRACTS
A process for culturing bacteria is disclosed in which is utilized as a bacterial nutrition a serum byproduced upon treatment of a natural rubber latex. The serum has an ample supply, a low cost, a stable quality and a sufficient activity over a wide variety of bacteria, thus contributing to accelerative growth for aerobic and anaerobic bacteria.
5026649
the membrane and disbursed into the fluid medium along the length of the membrane.
5026840 PHOTOCHEMICAL NUCLEIC ACID-LABELING REAGENT HAVING A POLYALKLAMINE SPACER
APPARATUS FOR GROWING T I S S U E C U L T U R E S IN V I T R O
Nanibhushan Dattagupta. James P Albarella assigned to Molecular Diagnostics Inc
Georg Lyman, Gregory Mathus. David Root assigned to Costar Corporation
A photochemical nucleic acid-labeling reagent of the form ula See PatentJor Chemical Structure wherein Q is a photoreactive residue of a nucleic acid-binding ligand; L is a detectable label residue; R is hydrogen, CI to C7-alkyl, aryl, hydroxy, or C 1 to CT-alkoxy; x is an integer from 2 through 7, and Y is an integer from 3 through 10: wherein R and x, respectively, can be the same or different each time they appear in the formula. The reagent is useful in the highly cffclent labeling of nucleic acids for the purpose of detection in hybridization assays.
Apparatus for growing tissue cultures in vitro, which permits a concentration gradient of nutrients to develop through a permeable membrane to which a sample of tissue is attached. The permeable membrane is attached to the bottom end of a tubular support that in turn hangs by a flange connected to its upper end on the top of a well containing the nutrients. Typically, the well is part of a tissue culture cluster dish. The flange of the support positions the support and membrane centrally in the well so as to avoid capillary action in the space between the well and support. The configuration of the support and its cooperation with the lid of the cluster dish also prevents the support and membrane from floating in the nutrient solution in the well. Openings in the support provide access for a pipette to add and withdraw fluid from the space between the well and membrane support and from the space below the membrane.
5026650 HORIZONTALLY ROTATED CELL CULTURE SYSTEM WITH A COAXIAL TUBULAR OXYGENATOR Ray P Schwarz, David A Wolf. Tinh T Trinh assigned to The United States of Amercia as represented by the Administrator of the National Aeronautics and Space Administration A bio-reactor system where cell growth microcarrier beads are suspended in a zero head space fluid medium by rotation about a horizontal axis and where the fluid is continuously oxygenated from a tubular membrane which rotates on a shaft together with rotation of the culture vessel. The oxygen is continuously throughput through
5028398 DEVICE FOR PROVIDING A CONTINUOUS BIOLOGICAL DECOMPOSITION OF MINERALS AND CONCENTRATES THEREOF Rolf Hallberg, UIf Edvardsson, S 135 55 Tyres Sweded A lying rotatable drum for continuous biological decomposition which includes at least one transversal partition for dividing the container interior into chambers. The partition has opening to transmit liquid between the chambers. Guide means are also provided.
5028524 ASSAY FOR ANTI-PRE-S ANTIBODY Yukio Fujisawa, Osamu Nishimura, Yasuaki ltoh, Kobe. Japan assigned to Takeda Chemical Industries Lid Assays for an anti-pre-S antibody in a human serum by an enzyme immunoassay in which a