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5155218 DNA encoding human 5-HT1D receptors
New Patents
5155218 DNA ENCODING HUMAN 5-HTlD RECEPTORS Richard L Weinshank, Theres Branchek, Paul R Hartig assigned to Neurogenetic Corporation This invention provides isolated nucleic acid molecules encoding human 5-HT 1D receptors, isolated proteins which are human 5-HTlD receptors, vectors comprising isolated nucleic acid molecules encoding human 5-HTlD receptors, mammalian cells comprising such vectors, antibodies directed to the human 5-HTlD receptors, nucleic acid probes useful for detecting nucleic acid encoding human 5-HT 1D receptors, antisense oligonucleotides complementary to any sequences of a nucleic acid molecule which encodes a human 5-HTlD receptor, pharmaceutical compounds related to human 5-HTlD receptors, and nonhuman transgenic animals which express DNA a normal or a mutant human 5-HTlD receptor. This invention further provides methods for determining ligand binding, detecting expression, drug screening, and treatment involving the human 5-HTlD receptor.
5156957 FOLLICLE STIMULATING HORMONE Vemuri Reddy, Nancy Hsiung, Anton K Beck, Edward G Berstine assigned to Genzyme Corporation Biologically active heterodimeric human FSH composed of an alpha subunit and a beta subunit, each subunit being synthesized by a cell having an expression vector containing heterologous DNA encoding the subunit.
5156958 GENE ENCODING A 30 KILODALTON OUTER MEMBRANE PROTEIN OF BORDETELLA PERTUSSIS AND METHOD OF RECOMBINANT PRODUCTION OF SAID PROTEIN Patricia A Reilly Cyanamid Company
5156955
assigned
to
American
The present invention relates to a nucleotide and amino acid sequence of a 30 kilodalton outer membrane protein of Bordetella pertussis. The invention also relates to host cells and vectors comprising the nucleotide sequence, as well as a vaccine composition comprising the substantially pure protein.
NUCLEOSIDE OXIDASE AND ASSAY METHOD UTILIZING SAME Yoshikaz Isono, Masami Hoshino, Otsu, Japan assigned to Otsuka Foods Co Ltd The present invention provides a novel nucleoside oxidase YT-1 serving as an enzyme for catalyzing oxidation reaction of a nucleoside, and oxidase being characterized in that the oxidase causes the nucleoside to react with molecular oxygen to produce a nucleoside-5’carboxylic acid via a nucleoside-5’-aldehyde without producing hydrogen peroxide, a process for producing the enzyme, a novel microorganism having ability to produce the enzyme, and a novel analysis or assay method for nucleosides and the like utilizing the enzyme.
5156959 METHOD TO EXPORT GENE PRODUCTS TO THE GROWTH MEDIUM OF GRAM NEGATIVE BACTERIA Lars Abrahmsen, Tomas Moks, Bjorn Nilsson, Mathias Uhlen, Stockholm, Sweden assigned to KabiGen AB A process for expressing proteins in Gram(-) bacteria and providing for extracellular secretion thereof, comprising the steps: a) introducing
5155218 DNA ENCODING HUMAN 5-HTlD RECEPTORS Richard L Weinshank, Theres Branchek, Paul R Hartig assigned to Neurogenetic Corporation This invention provides isolated nucleic acid molecules encoding human 5-HT 1D receptors, isolated proteins which are human 5-HTlD receptors, vectors comprising isolated nucleic acid molecules encoding human 5-HTlD receptors, mammalian cells comprising such vectors, antibodies directed to the human 5-HTlD receptors, nucleic acid probes useful for detecting nucleic acid encoding human 5-HT 1D receptors, antisense oligonucleotides complementary to any sequences of a nucleic acid molecule which encodes a human 5-HTlD receptor, pharmaceutical compounds related to human 5-HTlD receptors, and nonhuman transgenic animals which express DNA a normal or a mutant human 5-HTlD receptor. This invention further provides methods for determining ligand binding, detecting expression, drug screening, and treatment involving the human 5-HTlD receptor.
5156957 FOLLICLE STIMULATING HORMONE Vemuri Reddy, Nancy Hsiung, Anton K Beck, Edward G Berstine assigned to Genzyme Corporation Biologically active heterodimeric human FSH composed of an alpha subunit and a beta subunit, each subunit being synthesized by a cell having an expression vector containing heterologous DNA encoding the subunit.
5156958 GENE ENCODING A 30 KILODALTON OUTER MEMBRANE PROTEIN OF BORDETELLA PERTUSSIS AND METHOD OF RECOMBINANT PRODUCTION OF SAID PROTEIN Patricia A Reilly Cyanamid Company
5156955
assigned
to
American
The present invention relates to a nucleotide and amino acid sequence of a 30 kilodalton outer membrane protein of Bordetella pertussis. The invention also relates to host cells and vectors comprising the nucleotide sequence, as well as a vaccine composition comprising the substantially pure protein.
NUCLEOSIDE OXIDASE AND ASSAY METHOD UTILIZING SAME Yoshikaz Isono, Masami Hoshino, Otsu, Japan assigned to Otsuka Foods Co Ltd The present invention provides a novel nucleoside oxidase YT-1 serving as an enzyme for catalyzing oxidation reaction of a nucleoside, and oxidase being characterized in that the oxidase causes the nucleoside to react with molecular oxygen to produce a nucleoside-5’carboxylic acid via a nucleoside-5’-aldehyde without producing hydrogen peroxide, a process for producing the enzyme, a novel microorganism having ability to produce the enzyme, and a novel analysis or assay method for nucleosides and the like utilizing the enzyme.
5156959 METHOD TO EXPORT GENE PRODUCTS TO THE GROWTH MEDIUM OF GRAM NEGATIVE BACTERIA Lars Abrahmsen, Tomas Moks, Bjorn Nilsson, Mathias Uhlen, Stockholm, Sweden assigned to KabiGen AB A process for expressing proteins in Gram(-) bacteria and providing for extracellular secretion thereof, comprising the steps: a) introducing