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5171577 Process for the preparation of foams which can be used in the cosmetics and pharmaceutical field and foams obtained by this process
New Patents
and/or an aqueous extract from marinematerials, and an optional binder, is substantially impermeable to water and the medicament. The chamber is filled with the active agent in a viscous pharmaceutical formulation to improve the bioavailability and stability of the active agent. The chamber may be partly filled with gas. The buoyancy of the dosage form in water is manipulable by adjusting the volume and contents of the inner chamber.
5169640 PHARMACEUTICAL COMPOSITIONS Gordon France, Graham S Leonard, Kevin E Pearmain, Digswell, United Kingdom assigned to Smith Kline & French Laboratories Ltd The invention provides a solid pharmaceutical dosage form comprising: (i) cimetidine; and (ii) antacid, wherein at least part of the antacid is in the form of granules comprising a freely watersoluble solid diluent, the antacid, and a rapidly swellable water-insoluble disintegrant. Compositions of this type overcome the problem of the reduced bioavailability of cimetidine which can occur when cimetidine is co-administered with antacids.
5169849 NASAL PHARMACEUTICAL COMPOSITIONS Jean-Rene Acezat-Mispelter Francoise Kiechel, Danielle Plas, Rueil Malmaison, France assigned to Sandoz Ltd A nasal pharmaceutical composition incorporates a non-toxic agent which is capable of increasing the ciliary function e.g. caffeine and at least partially antagonizing the ciliary function depressant effect of the active agent e.g. dihydroergotamine or any other constituent present in the composition.
5169859 THIAZOLIDINONE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND PROCESS FOR PREPARING SAME
xxi
Istvan Szabadkai, Kalman Harsanyi, Bcla SzaboZsoltneHegedus, Eleme Ezer, Judi Matuz, Laslo Szporny, Katalin Saghy, Gyorgy Hajos, Attil Csehi, Gabor Balogh, Budapest, Hungary assigned to Richter Gedeon Vegyeszeti Gyar RT The present invention relates to novel compounds of the general formula (I) See Patent for Chemical Structure (I) wherein R means hydrogen or C1-4alkyl group; and Y stands for c y a n o , trifluoromethyl, aryloxy or aryl(CI-4alkyl)oxy group. The compounds according to the invention show a gastric acid secretion-inhibiting effect and therefore, they are useful for the treatment of gastric and duodenal ulcers. In addition, they exert a cytoprotective action against gastric laesions induced, e.g. by indomethacin or acid-containing alcohol.
5171219 PHARMACEUTICAL PREPARATION ADMINISTRATOR Keiji Fujioka, Yoshihir Takada, Ayumi Aisaka, Amagasaki, Japan assigned to Sumitomo Pharmaceuticals Co Ltd A preparation administrator has an administrator body including a solid preparation and having at its one end an inflow channel for solvent and at the other end an outflow channel for liquid preparation, a solvent container containing a solvent to dissolve, disperse or suspend the preparation and being connected to the inflow channel of the administrator body, and an ejector for ejecting the solvent together with the solid preparation in the body through the outflow channel of the body. A solid preparation in the administrator body is dissolved, or suspended or dispersed in the solvent fed from the solvent container and ejected as a liquid preparation through the outflow channel of the body.
5171577 PROCESS FOR THE PREPARATION OF FOAMS WHICH CAN BE USED IN THE COSMETICS AND PHARMACEUTICAL FIELD AND FOAMS OBTAINED BY THIS PROCESS Jacqueline Griat, Liliane Ayache, Ablon, France assigned to L'Oreal
and/or an aqueous extract from marinematerials, and an optional binder, is substantially impermeable to water and the medicament. The chamber is filled with the active agent in a viscous pharmaceutical formulation to improve the bioavailability and stability of the active agent. The chamber may be partly filled with gas. The buoyancy of the dosage form in water is manipulable by adjusting the volume and contents of the inner chamber.
5169640 PHARMACEUTICAL COMPOSITIONS Gordon France, Graham S Leonard, Kevin E Pearmain, Digswell, United Kingdom assigned to Smith Kline & French Laboratories Ltd The invention provides a solid pharmaceutical dosage form comprising: (i) cimetidine; and (ii) antacid, wherein at least part of the antacid is in the form of granules comprising a freely watersoluble solid diluent, the antacid, and a rapidly swellable water-insoluble disintegrant. Compositions of this type overcome the problem of the reduced bioavailability of cimetidine which can occur when cimetidine is co-administered with antacids.
5169849 NASAL PHARMACEUTICAL COMPOSITIONS Jean-Rene Acezat-Mispelter Francoise Kiechel, Danielle Plas, Rueil Malmaison, France assigned to Sandoz Ltd A nasal pharmaceutical composition incorporates a non-toxic agent which is capable of increasing the ciliary function e.g. caffeine and at least partially antagonizing the ciliary function depressant effect of the active agent e.g. dihydroergotamine or any other constituent present in the composition.
5169859 THIAZOLIDINONE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND PROCESS FOR PREPARING SAME
xxi
Istvan Szabadkai, Kalman Harsanyi, Bcla SzaboZsoltneHegedus, Eleme Ezer, Judi Matuz, Laslo Szporny, Katalin Saghy, Gyorgy Hajos, Attil Csehi, Gabor Balogh, Budapest, Hungary assigned to Richter Gedeon Vegyeszeti Gyar RT The present invention relates to novel compounds of the general formula (I) See Patent for Chemical Structure (I) wherein R means hydrogen or C1-4alkyl group; and Y stands for c y a n o , trifluoromethyl, aryloxy or aryl(CI-4alkyl)oxy group. The compounds according to the invention show a gastric acid secretion-inhibiting effect and therefore, they are useful for the treatment of gastric and duodenal ulcers. In addition, they exert a cytoprotective action against gastric laesions induced, e.g. by indomethacin or acid-containing alcohol.
5171219 PHARMACEUTICAL PREPARATION ADMINISTRATOR Keiji Fujioka, Yoshihir Takada, Ayumi Aisaka, Amagasaki, Japan assigned to Sumitomo Pharmaceuticals Co Ltd A preparation administrator has an administrator body including a solid preparation and having at its one end an inflow channel for solvent and at the other end an outflow channel for liquid preparation, a solvent container containing a solvent to dissolve, disperse or suspend the preparation and being connected to the inflow channel of the administrator body, and an ejector for ejecting the solvent together with the solid preparation in the body through the outflow channel of the body. A solid preparation in the administrator body is dissolved, or suspended or dispersed in the solvent fed from the solvent container and ejected as a liquid preparation through the outflow channel of the body.
5171577 PROCESS FOR THE PREPARATION OF FOAMS WHICH CAN BE USED IN THE COSMETICS AND PHARMACEUTICAL FIELD AND FOAMS OBTAINED BY THIS PROCESS Jacqueline Griat, Liliane Ayache, Ablon, France assigned to L'Oreal