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5382421 Contrast agents for magnetic resonance imaging of the small intestine and hepatobiliary system
New Patents
5381122 OPEN MRI MAGNET HAVING SUPPORT STRUCTURE
A
Laskaris Evangelos T; Minas Constantinos Schenectady, NY, UNITED STATES Assigned to General Electric Company An open magnetic resonance imaging (MRI) magnet having first and second spaced-apart superconductive coil assemblies connected by spaced-apart structural posts each having a first end portion attached to the coil form of the first coil assembly and a second end portion attached to the coil form of the second coil assembly. Each toroidal shaped coil form has radially spaced-apart inner and outer generally cylindrical shells and has longitudinally spacedapart inner and outer annular plates each attached to the inner and outer cylindrical shells. A superconductive coil surrounds, and is attached to, the outer surface of the outer cylindrical shell.
Subdomain metal or metal oxide particles covalently coupled to chemically reactive organic moieties and subsequently reacted together to form biodegradable magnetic microclusters are disclosed. The magnetic microcluster can be used as contrast agents in NMR imaging for the production of images suitable for use in diagnosis, for in vivo delivery and targeting of drugs, as in vivo, biodegradable agents for the sequestering of free metal ions in the treatment of metal driven disease.
5382902 METHOD FOR ELIMINATING MOTIONAL ARTIFACTS IN MAGNETIC RESONANCE IMAGING
5382421 CONTRAST AGENTS FOR MAGNETIC RESONANCE IMAGING OF THE SMALL INTESTINE AND HEPATOBILIARY SYSTEM White David; Engelstad Barry L; Muetterties Kur Oakland, CA, UNITED STATES Assigned to The Regents of the University of California A method is provided utilizing contrast agents which provide increased diagnostic information in the magnetic resonance image of the hepatobiliary system and alimentary tract, especially the small intestine. Novel contrast agents which N-carboxylated desferrioxamine B complzies with metal ions are provided.
5382468 BIODEGRADABLE MAGNETIC MICROCLUSTERS AND METHODS FOR MAKING THEM Chagnon Mark S; Ferris John R; Fiore Barry L; Carter Michelle J; Hamilton Tracy J Pelham, NH, UNITED STATES Assigned to Molecular Bioquest Inc
Taniguchi Yo; Yamamoto Etsuji JAPAN Assigned to Hitachi Ltd
Kokubunj i ,
A magnetic resonance imaging method for obtaining an image of an object laid in a space in which a static magnetic field is applied, so as to substantially eliminate motional artifacts. The method includes sequentially measuring a plurality of magnetic resonance views with a plurality of encodings by repeating a measurement sequence of exciting nuclear spins in said object, applying a phase-encoding field gradient along a first direction with programmed time integral to encode the excited spins, and detecting the encoded spins in the presence of a readout field gradient along a second direction to generate a magnetic resonance view so that measurements of magnetic resonance views with at least low-order encoding are obtained during the repetition of the measurement sequence. Thereafter respective magnetic resonance views are subjected to a first Fourier transformation so as to generate a plurality of projection views with a plurality of encodings forming a data matrix in a hybrid domain, displacements in respective projection views due to motion of the object are corrected using displacement information obtained from projection views with low-order encodings so as to generate a corrected data matrix in the hybrid domain, and the corrected data matrix is subjected to a second Fourier transformation so as to generate the image of the object.
5381122 OPEN MRI MAGNET HAVING SUPPORT STRUCTURE
A
Laskaris Evangelos T; Minas Constantinos Schenectady, NY, UNITED STATES Assigned to General Electric Company An open magnetic resonance imaging (MRI) magnet having first and second spaced-apart superconductive coil assemblies connected by spaced-apart structural posts each having a first end portion attached to the coil form of the first coil assembly and a second end portion attached to the coil form of the second coil assembly. Each toroidal shaped coil form has radially spaced-apart inner and outer generally cylindrical shells and has longitudinally spacedapart inner and outer annular plates each attached to the inner and outer cylindrical shells. A superconductive coil surrounds, and is attached to, the outer surface of the outer cylindrical shell.
Subdomain metal or metal oxide particles covalently coupled to chemically reactive organic moieties and subsequently reacted together to form biodegradable magnetic microclusters are disclosed. The magnetic microcluster can be used as contrast agents in NMR imaging for the production of images suitable for use in diagnosis, for in vivo delivery and targeting of drugs, as in vivo, biodegradable agents for the sequestering of free metal ions in the treatment of metal driven disease.
5382902 METHOD FOR ELIMINATING MOTIONAL ARTIFACTS IN MAGNETIC RESONANCE IMAGING
5382421 CONTRAST AGENTS FOR MAGNETIC RESONANCE IMAGING OF THE SMALL INTESTINE AND HEPATOBILIARY SYSTEM White David; Engelstad Barry L; Muetterties Kur Oakland, CA, UNITED STATES Assigned to The Regents of the University of California A method is provided utilizing contrast agents which provide increased diagnostic information in the magnetic resonance image of the hepatobiliary system and alimentary tract, especially the small intestine. Novel contrast agents which N-carboxylated desferrioxamine B complzies with metal ions are provided.
5382468 BIODEGRADABLE MAGNETIC MICROCLUSTERS AND METHODS FOR MAKING THEM Chagnon Mark S; Ferris John R; Fiore Barry L; Carter Michelle J; Hamilton Tracy J Pelham, NH, UNITED STATES Assigned to Molecular Bioquest Inc
Taniguchi Yo; Yamamoto Etsuji JAPAN Assigned to Hitachi Ltd
Kokubunj i ,
A magnetic resonance imaging method for obtaining an image of an object laid in a space in which a static magnetic field is applied, so as to substantially eliminate motional artifacts. The method includes sequentially measuring a plurality of magnetic resonance views with a plurality of encodings by repeating a measurement sequence of exciting nuclear spins in said object, applying a phase-encoding field gradient along a first direction with programmed time integral to encode the excited spins, and detecting the encoded spins in the presence of a readout field gradient along a second direction to generate a magnetic resonance view so that measurements of magnetic resonance views with at least low-order encoding are obtained during the repetition of the measurement sequence. Thereafter respective magnetic resonance views are subjected to a first Fourier transformation so as to generate a plurality of projection views with a plurality of encodings forming a data matrix in a hybrid domain, displacements in respective projection views due to motion of the object are corrected using displacement information obtained from projection views with low-order encodings so as to generate a corrected data matrix in the hybrid domain, and the corrected data matrix is subjected to a second Fourier transformation so as to generate the image of the object.