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5382429 Bacillus thuringiensis protein toxic to coleopteran insects
732
PATENT ABSTRACTS
The present invention relates generally to sodium channel proteins and more particularly to mammalian cardiac sodium channel proteins, to DNA sequences encoding sodium channel proteins, to the polypeptide products of recombinant expression of these DNA sequences, to peptides whose sequences are based on amino acid sequences deduced from these DNA sequences, to antibodies specific for such proteins and peptides, and to procedures for detection and quantitation of such proteins and nucleic acids related thereto, as well as to procedures relating to the development of anti-arrhythmic and cardiotonic di'ugs.
Hottinger Herber; Mignot Olivier; Mollet Beat Blonay, SWITZERLAND Assigned to Nestec S A
5382425
5382509
RECOMBINANT SWINEPOX VIRUS
METHOD AND KIT FOR THE DIAGNOSIS OF HUMAN PAPILLOMAVIRUS TYPE 41
Cochran Mark; Junker David Carlsbad, CA, UNITED STATES Assigned to Syntro Corporation The present invention relates to a recombinant swiuepox virus capable o f replication comprising foreign DNA inserted into a site in the swine,pox viral DNA which is not essential for replication of the swinepox virus. The invention further relates to homology vectors which produce recombinant swinepox viruses by inserting foreign DNA into swinepox viral DNA.
5382438 PREPARATION OF YOGURT WITH LAC(-) L. BULGARICUS
Yogurt is prepared by inoculating and fermenting a milk with a strain of Streptococcus thermophilns and a lac(-) mutant strain of Lactobacillus bulgaricns, the DNA of which has a deletion of at least part of the beta-galactosidase gene.
Grimmel Margitta; de Villiers Ethel-Michele Neustadt, GERMANY Assigned to Behringwerke Aktiengesellschaft The invention relates to isolation of human papillomavirus type 41, partial characterization of its genome and its cloning in pUC 19. This opens up an access to early diagnosis of skin tumors associated with HPV 41.
5382510 5382429 BACILLUS THURINGIENSIS PROTEIN TOXIC TO COLEOPTERAN INSECTS
METHODS OF DIAGNOSING PRECANCER OR CANCER STATES USING PROBES FOR DETECTING MUTANT P53
Donovan William P; Rupar Mark J; Slaney Annette C; Johnson Timothy B Levittown, PA, UNITED STATES Assigned to Ecogen Inc
Levine Arnold J; Shenk Thomas E; Finlay Cathy A Princeton, NJ, UNITED STATES Assigned to The Trustees of Princeton University
A purified and isolated cryIII-type gene was obtained from a novel B.t. strain. The gene has a uudeotide base sequence coding for the amino acid sequence illustrated in FIG. 1 . The 74.4 kDa protein produced by this gene is an irregularly shaped crystal that is toxic to coleopteran insects, inclndiag Colorado potato beetle and insects of the genus Diabrotica.
A panel of probes that detect and distinguish between sets of human p53 gene or protein mutations that frequently occur or are selected for in pre-cancer and cancer cells, each set giving rise to a phenotype that is different from that of wildtype p53 and of at least one other set of p53 mutants.
PATENT ABSTRACTS
The present invention relates generally to sodium channel proteins and more particularly to mammalian cardiac sodium channel proteins, to DNA sequences encoding sodium channel proteins, to the polypeptide products of recombinant expression of these DNA sequences, to peptides whose sequences are based on amino acid sequences deduced from these DNA sequences, to antibodies specific for such proteins and peptides, and to procedures for detection and quantitation of such proteins and nucleic acids related thereto, as well as to procedures relating to the development of anti-arrhythmic and cardiotonic di'ugs.
Hottinger Herber; Mignot Olivier; Mollet Beat Blonay, SWITZERLAND Assigned to Nestec S A
5382425
5382509
RECOMBINANT SWINEPOX VIRUS
METHOD AND KIT FOR THE DIAGNOSIS OF HUMAN PAPILLOMAVIRUS TYPE 41
Cochran Mark; Junker David Carlsbad, CA, UNITED STATES Assigned to Syntro Corporation The present invention relates to a recombinant swiuepox virus capable o f replication comprising foreign DNA inserted into a site in the swine,pox viral DNA which is not essential for replication of the swinepox virus. The invention further relates to homology vectors which produce recombinant swinepox viruses by inserting foreign DNA into swinepox viral DNA.
5382438 PREPARATION OF YOGURT WITH LAC(-) L. BULGARICUS
Yogurt is prepared by inoculating and fermenting a milk with a strain of Streptococcus thermophilns and a lac(-) mutant strain of Lactobacillus bulgaricns, the DNA of which has a deletion of at least part of the beta-galactosidase gene.
Grimmel Margitta; de Villiers Ethel-Michele Neustadt, GERMANY Assigned to Behringwerke Aktiengesellschaft The invention relates to isolation of human papillomavirus type 41, partial characterization of its genome and its cloning in pUC 19. This opens up an access to early diagnosis of skin tumors associated with HPV 41.
5382510 5382429 BACILLUS THURINGIENSIS PROTEIN TOXIC TO COLEOPTERAN INSECTS
METHODS OF DIAGNOSING PRECANCER OR CANCER STATES USING PROBES FOR DETECTING MUTANT P53
Donovan William P; Rupar Mark J; Slaney Annette C; Johnson Timothy B Levittown, PA, UNITED STATES Assigned to Ecogen Inc
Levine Arnold J; Shenk Thomas E; Finlay Cathy A Princeton, NJ, UNITED STATES Assigned to The Trustees of Princeton University
A purified and isolated cryIII-type gene was obtained from a novel B.t. strain. The gene has a uudeotide base sequence coding for the amino acid sequence illustrated in FIG. 1 . The 74.4 kDa protein produced by this gene is an irregularly shaped crystal that is toxic to coleopteran insects, inclndiag Colorado potato beetle and insects of the genus Diabrotica.
A panel of probes that detect and distinguish between sets of human p53 gene or protein mutations that frequently occur or are selected for in pre-cancer and cancer cells, each set giving rise to a phenotype that is different from that of wildtype p53 and of at least one other set of p53 mutants.