5604293 Recombinant human basic fibroblast growth factor

5604293 Recombinant human basic fibroblast growth factor

678 PATENT ABSTRACTS Additionally, the system comprises a mechanism for comparing said libraries to form comparisons. The comparing mechanism is in ...

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678

PATENT ABSTRACTS

Additionally, the system comprises a mechanism for comparing said libraries to form comparisons. The comparing mechanism is in communication with the said libraries. The system also comprises a mechanism for combining the comparisons to construct a map of the clones relative to the genome. The said combining mechanism is in communication with the comparisons. Further, the system comprises a mechanism for determining the sequence of the genome by means of said map. The said determining mechanism is in communication with said map. The present invention additionally pertains to a method for producing a gene of a genome.

5604293 RECOMBINANT HUMAN BASIC FIBROBLAST GROWTH FACTOR Fiddes John; Abraham Judith A Palo Alto, CA, UNITED STATES Assigned to Scios lnc The DNA sequences encoding human and bovine acidic and basic fibroblast growth factors (FGF) can be recombinantly expressed to obtain practical amounts of proteins useful in effecting wound healing and related tissue repair.

5607844 MAMMALIAN AUGMENTER OF LIVER REGENERATION AND VARIANTS THEREOF Francavilla Antonio T; Hagiya Michio; Starzl Thomas E Pittsburgh, PA, UNITED STATES Assigned to University of Pittsburgh Full-length cDNA clones have been isolated encoding purified augmenter of liver regeneration (ALR) polypeptides prepared from the cytosol of livers from weanling rats and from humans. The full-length clone from the rat is a 1226 bp cDNA containing an 81 bp 5'-untranslated region, a 594 bp coding region and a 551 bp 3'-untranslated region. The coding region encodes three proteins with estimated molecular weights of 15,081,20,193 and 22,835. The full-length clone from the human consists of a 727 bp cDNA containing a 4 bp 5'-untranslated region, a 615 bp coding region and a 108 lap 3'-untranslated region, including the termination codon TAG and the poly (A) region. The 615 bp coding region encodes four proteins, human ALR-V1, ALR-V2, ALR-V3 and ALR, having estimated molecular weights of 23,448, 20,834, 20,703 and 15,028, respectively.

5607849 5607842 USE OF TRNA GENES TO STABILIZE THE INHERITANCE OF UNSTABLE PLASMIDS IN POPULATIONS OF GROWING CELLS Cohen Stanley N; Vuml ogtli Martin Portola Valley, CA, UNITED STATES Assigned to The Board of Trustees of the Leland Stanford Junior University Expression systems are provided, where plasmids can be safely maintained in a prokaryotic host, by providing for a tRNA gene for an essential tRNA in a tRNA gene negative background. A non-selective medium can be employed to permit vigorous growth of the host and efficient expression of a protein of interest.

GENE ENCODING TRANSGLUTAMINASE DERIVED FROM FISH Yasueda Hisashi; Nakanishi Kazuo; Motoki Masao; Nagase Kazuo; Matsui Hiroshi Kawasaki, JAPAN Assigned to Ajinomoto Co Inc The present invention relates to a DNA fragment having a gene derived from fish which codes for a polypeptide possessing transglutaminase activity, a recombinant plasmid comprising a fish-derived DNA fragment which codes for a transglutaminase, a transformant into which a recombinant plasmid comprising a fish-derived DNA fragment which codes for a transglutaminase is introduced, and a method for the production of a transglutaminase, comprising culturing a transformant containing a fish-derived DNA fragment which codes for a transglutaminase.