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Antibiotic therapy. By Henry Welch and Charles N. Lewis. The Arundel Press, Inc., Washington, D. C., 1951. xiv + 562 pp. Illustrated. 15 × 22 cm. Price $10
Book Reviews
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Antibiotic Therapy. By HENRY WELCH and CHARLESN. LEWIS. The Arundel Press, Inc., 562 pp. IIlusWashington, D. C., 1951. xiv trated. 15 x 22 cm. Price 810. Here is a book which should be of considerable interest to practicing pharmacists and to pharmaceutical chemists. The first half of the book, particularly, includes information on tyrothricin, penicillin, streptomycin, dihydrostreptomycin, bacitracin, aureomycin, chloramphenicol, terramycin, polymyxin, neomycin, mycomycin, viomycin, and subtilin, of special interest and use to practicing pharmacists. The first chapter of the book deals with the isolation and the development of the antibiotics and includes definitions of terms. Chapters 2 to 0, inclusive, are designed to summarize essential information on the antimicrobial spectrum, the pharmacology, and the dosage forms available for each antibiotic discussed. Each chapter is preceded by a photograph and a short biographical sketch of the discoverer of each antibiotic. In the third part of the book will be found a discussion of the treatment of specific diseases, in which the experience and results of the use of the several antibiotics are s u n marized. The book is documented with significant references, and is well indexed to facilitate the location of specific information quickly. Dr. Welch, who is Director, and Dr. Lewis, who is Medical Officer in the Division of Antibiotics of the Food and Drug Administration, have brought together in their book an enormous amount of information concerning the antibiotics in common use. Through the design of the book and the style of presentation it can be used advantageously by practicing pharmacists as an authoritative source of information upon which to base answers to the many questions asked them by physicians relating to the present status of individual antibiotics. The information on dosage forms alone would warrant acquisition of the book, but in addition to this, the reader is supplied with answers to questions on indications and contraindications for use in the treatment of many infections, desirable routes of administration, the danger of the development of resistant strains of infective organisms, determination and maintenance of bactericidal blood levels, incidence and nature of allergic and other side reactions, and many other phases of the use of antibiotics with which the well-informed pharmacist should be familiar. Pharmaceutical chemists may be disappointed that the chemistry of the antibiotics is not discussed. It should be borne in mind that this phase of the subject is too extensive in scope to be included in a book limited t o antibiotic therapy. The book can be unqualifiedly recommended as a guide and source of information to all who require more than a superficial knowledge of the many problems involved in the rational use of antibiotics in the treatment of disease.
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Federal Food, Drug, and Cosmetic Act Judicial and Administratioe Record, 1949-1950. By VINCENT A. KLEINFELDand CHARLESWESLEYI ~ U N N . Commerce Clearing House, Inc., Chicago, 1951. 543 pp. 17.5 x 25.3 cm. Price $10.25. This is the second of a series, the first of which was published early in 1951. [See THISJOURNAL, 40, 304(1951).] Like the first book in the series, this new one is logically arranged and clearly written and will be useful to anyone whose business or profession is regulated by the Act. One part of the book contains all opinions and decisions not otherwise generally available, except in Food and Drug Administration Notices of Judgment and in the loose-leaf service of the Commerce Clearing House Food, Drug, Cosmetic Law Reports. This material consists of wmmaries, each of which includes specific references to the various subsections of the Act involved. It also includes significant opinions under the 1906 Act not included in the first book covering the period 1907-1949. The second part of the book includes “statements of general policy or interpretation.” This section is especially valuable in indicating the attitude of the Food and Drug Administration, and reasoning by analogy it makes it possible for the reader to predict what the attitude of the F. D. A. will be on comparable problems. In the third section certain definitions and standards for foods promulgated by the Federal Security Administrator are reproduced in full. The value of the book both to professional and lay readers is cnhanced by a table of references from law to interpretations, a cumulative table of cases, and a dctaikd index. The authors deserve special credit for planning the design of the book and writing the several summaries in clear and unambiguous style, and the publishers are to be complimented upon the excellence of the typography and the printing and binding. ilfetabolic Methods (Clinical Procedures in the Study of Metabolic Functions). By C . FRANK CONSOLAZIO,ROBERTE. JOHNSON,and EVELYN MAREK. C. V. Mosby Company, St. Louis, 1951. 471 pp. Illustrated. 18 x 25.5 cm. Price $6.75. In this book methods are presented in detail which have proved useful to the authors in research on various aspects of mammalian metabolism. The collection and storage of specimens, instrumentation methods, biochemical procedures, microbiological procedures, and physiological measurements are discussed in the first six sections of the book. Studies in the field, techniques for metabolic wards, and clinical laboratory procedures are discussed in the next three sections. In Stlctiou 10 references to standard works on statistical methods are listed, and in Section 11 considerable miscellaneous data of use to research workers in mammalian metabolism are included in tabular form.
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Antibiotic Therapy. By HENRY WELCH and CHARLESN. LEWIS. The Arundel Press, Inc., 562 pp. IIlusWashington, D. C., 1951. xiv trated. 15 x 22 cm. Price 810. Here is a book which should be of considerable interest to practicing pharmacists and to pharmaceutical chemists. The first half of the book, particularly, includes information on tyrothricin, penicillin, streptomycin, dihydrostreptomycin, bacitracin, aureomycin, chloramphenicol, terramycin, polymyxin, neomycin, mycomycin, viomycin, and subtilin, of special interest and use to practicing pharmacists. The first chapter of the book deals with the isolation and the development of the antibiotics and includes definitions of terms. Chapters 2 to 0, inclusive, are designed to summarize essential information on the antimicrobial spectrum, the pharmacology, and the dosage forms available for each antibiotic discussed. Each chapter is preceded by a photograph and a short biographical sketch of the discoverer of each antibiotic. In the third part of the book will be found a discussion of the treatment of specific diseases, in which the experience and results of the use of the several antibiotics are s u n marized. The book is documented with significant references, and is well indexed to facilitate the location of specific information quickly. Dr. Welch, who is Director, and Dr. Lewis, who is Medical Officer in the Division of Antibiotics of the Food and Drug Administration, have brought together in their book an enormous amount of information concerning the antibiotics in common use. Through the design of the book and the style of presentation it can be used advantageously by practicing pharmacists as an authoritative source of information upon which to base answers to the many questions asked them by physicians relating to the present status of individual antibiotics. The information on dosage forms alone would warrant acquisition of the book, but in addition to this, the reader is supplied with answers to questions on indications and contraindications for use in the treatment of many infections, desirable routes of administration, the danger of the development of resistant strains of infective organisms, determination and maintenance of bactericidal blood levels, incidence and nature of allergic and other side reactions, and many other phases of the use of antibiotics with which the well-informed pharmacist should be familiar. Pharmaceutical chemists may be disappointed that the chemistry of the antibiotics is not discussed. It should be borne in mind that this phase of the subject is too extensive in scope to be included in a book limited t o antibiotic therapy. The book can be unqualifiedly recommended as a guide and source of information to all who require more than a superficial knowledge of the many problems involved in the rational use of antibiotics in the treatment of disease.
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Federal Food, Drug, and Cosmetic Act Judicial and Administratioe Record, 1949-1950. By VINCENT A. KLEINFELDand CHARLESWESLEYI ~ U N N . Commerce Clearing House, Inc., Chicago, 1951. 543 pp. 17.5 x 25.3 cm. Price $10.25. This is the second of a series, the first of which was published early in 1951. [See THISJOURNAL, 40, 304(1951).] Like the first book in the series, this new one is logically arranged and clearly written and will be useful to anyone whose business or profession is regulated by the Act. One part of the book contains all opinions and decisions not otherwise generally available, except in Food and Drug Administration Notices of Judgment and in the loose-leaf service of the Commerce Clearing House Food, Drug, Cosmetic Law Reports. This material consists of wmmaries, each of which includes specific references to the various subsections of the Act involved. It also includes significant opinions under the 1906 Act not included in the first book covering the period 1907-1949. The second part of the book includes “statements of general policy or interpretation.” This section is especially valuable in indicating the attitude of the Food and Drug Administration, and reasoning by analogy it makes it possible for the reader to predict what the attitude of the F. D. A. will be on comparable problems. In the third section certain definitions and standards for foods promulgated by the Federal Security Administrator are reproduced in full. The value of the book both to professional and lay readers is cnhanced by a table of references from law to interpretations, a cumulative table of cases, and a dctaikd index. The authors deserve special credit for planning the design of the book and writing the several summaries in clear and unambiguous style, and the publishers are to be complimented upon the excellence of the typography and the printing and binding. ilfetabolic Methods (Clinical Procedures in the Study of Metabolic Functions). By C . FRANK CONSOLAZIO,ROBERTE. JOHNSON,and EVELYN MAREK. C. V. Mosby Company, St. Louis, 1951. 471 pp. Illustrated. 18 x 25.5 cm. Price $6.75. In this book methods are presented in detail which have proved useful to the authors in research on various aspects of mammalian metabolism. The collection and storage of specimens, instrumentation methods, biochemical procedures, microbiological procedures, and physiological measurements are discussed in the first six sections of the book. Studies in the field, techniques for metabolic wards, and clinical laboratory procedures are discussed in the next three sections. In Stlctiou 10 references to standard works on statistical methods are listed, and in Section 11 considerable miscellaneous data of use to research workers in mammalian metabolism are included in tabular form.
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