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The essential oils. Vol. IV. By Ernest Guenther. D. Van Nostrand Company, Inc., New York, 1950. xiv + 752 pp. Illustrated. 15 × 23.5 cm. Price $12
Book Reviews
Biological Standardization. 2nd ed. By J. H. BURN, with chapters by D. J. FINNEY and L. G. GOODWIN. Oxford University Press, New York, 1950. x 440 pp. Illustrated. 14 x 23.5 cm. Price $6.75. Pharmacologists will be glad to see a new edition of this book, the methods of the first edition having been largely replaced or improved upon to such an extent that it had almost lost its usefulness. This new edition lacks the completeness of coverage of the old edition, though this is understandable when one compares the total volume of pharmacological literature of the two periods. The book retains, however, its full value as an introductory text for biological assay, and the methods that are included are, for the most part, modern. Readers will be pleased t o see the chapter, “Mathematical Treatment of Results,” replaced by a chapter of onehundred and fifty pages entitled, “Statistical Analysis.” Pharmacologists will be particularly pleased to see that examples used in this chapter, and they are numerous, are practical bioassay problems. Also of special interest are well-described methods for biological assay of local anesthetics, drugs affecting gastric secretion, quinidine-like compounds, curariforms, anthelmintics, and other newer types of drugs which are still in developmental stages. Many workers in this country will be disappointed that the second edition does not cover adequately the developments in bioassay of digitalis and similar drugs. Though this book does not have the completeness of the first edition at its time of publication, the second edition remains a valuable tool t o the pharmacologist and bioassayist because of the thorough treatment given those subjects that it does include.
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from the members of the Gramiwe, Lauraceae, Burseraceae, Myrtaceae, Umbelliferae.and Geraniaceae families. As in the previous volume, each monograph covers the history, geographic origin, botanical description, methods of cultivation of the plant from which the oil is derived, techniques of production and yield of oil, physical and chemical properties, chemical compositions, and use in the industry. With the appearance of each succeeding volume of The Essential Oils comes a greater appreciation of the magnitude of the task undertaken by Ernest Guenther when he started to write a comprehensive series of books covering the essential oils. He and his associates are t o be congratulated upon the success of the undertaking thus far in its progress toward completion. All who are interested in essential oils from any standpoint will look forward with keen anticipation t o the appearance of the succeeding volume which is promised for future publication.
Cell Physiology and Pharmacology. By J. F. DANIELLI. Elsevier Publishing Company, Inc., New York, 1950. viii 156 pp. Illustrated. 15.5 x 23.5 cm. Price $3. This book, based upon a series of lectures given at University College, London, is intended t o stimulate more effective thought in the planning of research on new drugs. The author recognizes the great need that exists today for some logical approach t o the development of new drugs which will make it possible in the future t o avoid the synthesis of such large numbers of compounds in order to fmd one that is useful. He recognizes as well the tremendous loss of effort on the part of the pharmacologists who must make series of tests on thousands The Essential Oils. Vol. IV. By ERNESTGUEN- of chemicals that are without value to medicine. THER. D. Van Nostrand Company, Lnc., New I n attempting t o achieve his task, the author preYork, 1950. xiv 752 pp. Illustrated. 15 x 23.5 sents in a well-integrated fashion the various theories cm. Price $12. of cell structure and physiology which have t o do with drug action, instructing that these theories The fourth volume of this monumental series of books on the essential oils was published in October. and mechanisms serve as a basis of thought for Volume I, published in 1948, covered the history, planning new drugs. Although a number of books on the mechanism of chemistry, biology, origin, functions, methods of production, and analyses of essential oils from a drug action have appeared recently, this one has a general point of view [THIS JOURNAL, 37,214(1948)]. definite place of its own. It presents a broader In the second volume, published in 1949, the con- view of the subject than do most books, with less stituents of essential oils including the hydrocar- detail in most subjects, it is true, but in a more thought-provoking manner. At the same time, it is bons, the terpenes, the sesquiterpenes and their type of concise oxygenated derivatives, were discussed quite in remarkably easy to follow-the detail from the standpoint of occurrence, isolation, writing which adds one simple point t o another, piling them up until some general conclusions can identification, properties, and use [THISJOURNAL, 38, 665(1949)]. Volume 111. also published in be drawn. At the same time oversimplications are 1949, was devoted t o monographs on essential oils few in number. The subject is begun with a consideration of the from members of the Rutaceae and Labiatae plant families [THISJOURNAL, 39, 243(1950)]. Volume IV structure of the cell, then the biological changes of continues according t o the design established for the the cell during growth, the structure of chromosomes third volume and covers the essential oils obtained and the relative sizes and quantities of cell constit-
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703
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Biological Standardization. 2nd ed. By J. H. BURN, with chapters by D. J. FINNEY and L. G. GOODWIN. Oxford University Press, New York, 1950. x 440 pp. Illustrated. 14 x 23.5 cm. Price $6.75. Pharmacologists will be glad to see a new edition of this book, the methods of the first edition having been largely replaced or improved upon to such an extent that it had almost lost its usefulness. This new edition lacks the completeness of coverage of the old edition, though this is understandable when one compares the total volume of pharmacological literature of the two periods. The book retains, however, its full value as an introductory text for biological assay, and the methods that are included are, for the most part, modern. Readers will be pleased t o see the chapter, “Mathematical Treatment of Results,” replaced by a chapter of onehundred and fifty pages entitled, “Statistical Analysis.” Pharmacologists will be particularly pleased to see that examples used in this chapter, and they are numerous, are practical bioassay problems. Also of special interest are well-described methods for biological assay of local anesthetics, drugs affecting gastric secretion, quinidine-like compounds, curariforms, anthelmintics, and other newer types of drugs which are still in developmental stages. Many workers in this country will be disappointed that the second edition does not cover adequately the developments in bioassay of digitalis and similar drugs. Though this book does not have the completeness of the first edition at its time of publication, the second edition remains a valuable tool t o the pharmacologist and bioassayist because of the thorough treatment given those subjects that it does include.
+
from the members of the Gramiwe, Lauraceae, Burseraceae, Myrtaceae, Umbelliferae.and Geraniaceae families. As in the previous volume, each monograph covers the history, geographic origin, botanical description, methods of cultivation of the plant from which the oil is derived, techniques of production and yield of oil, physical and chemical properties, chemical compositions, and use in the industry. With the appearance of each succeeding volume of The Essential Oils comes a greater appreciation of the magnitude of the task undertaken by Ernest Guenther when he started to write a comprehensive series of books covering the essential oils. He and his associates are t o be congratulated upon the success of the undertaking thus far in its progress toward completion. All who are interested in essential oils from any standpoint will look forward with keen anticipation t o the appearance of the succeeding volume which is promised for future publication.
Cell Physiology and Pharmacology. By J. F. DANIELLI. Elsevier Publishing Company, Inc., New York, 1950. viii 156 pp. Illustrated. 15.5 x 23.5 cm. Price $3. This book, based upon a series of lectures given at University College, London, is intended t o stimulate more effective thought in the planning of research on new drugs. The author recognizes the great need that exists today for some logical approach t o the development of new drugs which will make it possible in the future t o avoid the synthesis of such large numbers of compounds in order to fmd one that is useful. He recognizes as well the tremendous loss of effort on the part of the pharmacologists who must make series of tests on thousands The Essential Oils. Vol. IV. By ERNESTGUEN- of chemicals that are without value to medicine. THER. D. Van Nostrand Company, Lnc., New I n attempting t o achieve his task, the author preYork, 1950. xiv 752 pp. Illustrated. 15 x 23.5 sents in a well-integrated fashion the various theories cm. Price $12. of cell structure and physiology which have t o do with drug action, instructing that these theories The fourth volume of this monumental series of books on the essential oils was published in October. and mechanisms serve as a basis of thought for Volume I, published in 1948, covered the history, planning new drugs. Although a number of books on the mechanism of chemistry, biology, origin, functions, methods of production, and analyses of essential oils from a drug action have appeared recently, this one has a general point of view [THIS JOURNAL, 37,214(1948)]. definite place of its own. It presents a broader In the second volume, published in 1949, the con- view of the subject than do most books, with less stituents of essential oils including the hydrocar- detail in most subjects, it is true, but in a more thought-provoking manner. At the same time, it is bons, the terpenes, the sesquiterpenes and their type of concise oxygenated derivatives, were discussed quite in remarkably easy to follow-the detail from the standpoint of occurrence, isolation, writing which adds one simple point t o another, piling them up until some general conclusions can identification, properties, and use [THISJOURNAL, 38, 665(1949)]. Volume 111. also published in be drawn. At the same time oversimplications are 1949, was devoted t o monographs on essential oils few in number. The subject is begun with a consideration of the from members of the Rutaceae and Labiatae plant families [THISJOURNAL, 39, 243(1950)]. Volume IV structure of the cell, then the biological changes of continues according t o the design established for the the cell during growth, the structure of chromosomes third volume and covers the essential oils obtained and the relative sizes and quantities of cell constit-
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703
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