biomedical applications of liquid chromatography IV

biomedical applications of liquid chromatography IV

482 Journal of Chromatography, Biomedical Applications 278 (1983)482 Else&r Science PublishersB-V., Amsterdam- Printed in The Netherlands CHROMBIO...

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482

Journal of Chromatography, Biomedical Applications

278 (1983)482

Else&r Science PublishersB-V., Amsterdam- Printed in The Netherlands

CHROMBIO. 1946

Book Review applications of liquid chromatography IV, edited by G.L. Hawk (associate editors R.F. Hutton, G. Johnston and Ch. Mel), Marcel Dekker, New York, Basel, 1982, XVII + 367 pp., price SFr. 156.00, ISBN 0-8247-1842-O.

Biological/biomedical

The fourth volume of this monograph represents a collection of 25 papers presented at the 4th Liquid Chromatography Symposium held in Amsterdam, The Netherlands, April 28 and 29, 1981 [for reviews of previous volumes see J. Chromatogr., 181 (1980) 516; 183 (1980) 260; and 233 (1982) 4421. Most of the papers have kept the form of original contributions or short reviews from the areas of clinical chemistry, drug analysis and chromatography of peptides and proteins. One paper is devoted to general techniques (selective chemically bonded phases). The topic of the book is rather wide (“biological” applications) and therefore it is possible to find contributions that would not be expected here, e.g., peptide synthesis and analysis of plant material. The subject of the symposium and concomitantly the contents of these Proceedings reflect current trends in the biomedical field - always the most interesting feature of this category of publication. Attention in comparison to the preceding volumes is focused on chromatography of peptides and proteins and on drug monitoring. Contributions from the area of clinical chemistry deal mainly with catecholamines and their metabolites. The paper of Van Gennip et al. is quite interesting from the point of view of clinical practice. (Why then is Wadman et al. reported as the author in the running title?) This paper deals with the screening of inborn errors of purine and pyrimidine metabolism. In the present volume the Editors attempted to arrange the individual papers according to the categories of the compounds separated, helping to constitute a clear view of the whole volume. Unfortunately, the quality of the book is devaluated by the Index which contains so many errors as is rarely seen. It appears that no proofing has been done on this particular part of the book. Otherwise, it is difficult to explain that the G heading is doubled and that letters are missing, e.g., “Des-Tyr- -en“). For obscure -endorphin”, or entire words (“kynurenic dorphin” or “ reasons several entries refer to a footnote when there is none in the Index, b?, and “cefazolinb “. Quite enjoyable are the entries which e.g., “cefaloridine refer to a blank page (“bufotenine 256” and “dimethyltryptamine 256”). There are also situations where the entries refer to a page where the particular compound is not spoken of at all; or, on the contrary, there are no references to a page where a compound is dealt with. It is very likely that these drawbacks are on account of the poor desk-editorial work and that they are not the fault of the Editors; however, they devaluate considerably the work done by the Editors.