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Contents of Volume 4
Mitochondrion 4 (2004) 815–818 www.elsevier.com/locate/mito
Contents of volume 4 No. 1, June 2004 Regular papers Import and orientation of the MWFE protein in mitochondrial NADH-ubiquinone oxidoreductase N. Yadava, I.E. Scheffler (USA) Absence of accessory subunit in the DNA polymerase g purified from yeast mitochondria P. Lucas, J.-P. Lasserre, J. Plissonneau, M. Castroviejo (France) Interaction of mitochondrial elongation factor Tu with aminoacyl-tRNAs S.E. Hunter, L.L. Spremulli (USA) Erythromycin as a potential precipitating agent in the onset of Leber’s hereditary optic neuropathy C.C. Luca, B.L. Lam, C.T. Moraes (USA) Pitfalls in restriction fragment length polymorphism analysis of Leber’s hereditary optic neuropathy patients F. Carrara, P.F. Chinnery, P.Y.W. Man, M. Zeviani, V. Tiranti (Italy, UK) Pathogenicity of missense mutations in SURF1 deficiency inducing the Leigh syndrome. Importance in diagnosis A. Dubot, E. Hervouet, G. Mandon, M.T. Zabot, C. Godinot (France) Higher respiratory rates and improved creatine stimulation in brain mitochondria isolated with anti-oxidants G.J. Brewer, T.T. Jones, T. Wallimann, U. Schlattner (USA, Switzerland) Abstracts Abstracts from ‘Mitochondrial Medicine 2004’ 4–7 August, 2004, Pittsburgh, PA, USA Abstract index
59 83
Calendar of Events
87
Guide for Authors
89
1 13 21 31 37 41 49
Nos. 2–3, July 2004 Special Issue: Mitochondria, HIV and Antiretroviral Therapy Guest Editor: M. Gerschenson Foreword M. Gerschenson (USA) Clinical Mitochondrial injury in the pathogenesis of antiretroviral-induced hepatic steatosis and lactic acidemia L. Day, C. Shikuma, M. Gerschenson (USA) Role of mitochondria in HIV lipoatrophy: insight into pathogenesis and potential therapies G.A. McComsey, U.A. Walker (USA, Germany) HIV-associated dementia, mitochondrial dysfunction, and oxidative stress V. Valcour, B. Shiramizu (USA) HIV neuromuscular disease and mitochondrial function L. Estanislao, D. Thomas, D. Simpson (USA) Cardiomyopathy, nucleoside reverse transcriptase inhibitors and mitochondria are linked through AIDS and its therapy W. Lewis (USA)
93
95 111 119 131 141
816
Volume contents
HIV-associated mitochondrial toxicity in pregnancy L.E. Kamemoto, B. Shiramizu, M. Gerschenson (USA) l-Carnitine and acetyl-l-carnitine in the treatment of complications associated with HIV infection and antiretroviral therapy I. Ilias, I. Manoli, M.R. Blackman, P.W. Gold, S. Alesci (USA, Greece) HIV disease progression and limited antiretroviral treatment options for a HIV-1 infected individual with myoclonic epilepsy associated with ragged red fibers E.J. Walsh, S. Souza, M. Gerschenson, C. Shikuma, D. Chow (USA) Cumulative insults to mitochondrial function may promote the emergence of ‘syndrome X’ and diabetes mellitus in HIV/HCV co-infected patients M.P. Revuelta (USA)
153 163
169
175
Basic Science Potential roles for uncoupling proteins in HIV lipodystrophy D. Nolan, C. Pace (Australia) Direct effects of nucleoside reverse transcriptase inhibitors on rat cardiac mitochondrial bioenergetics K.C. Lund, K.B. Wallace (USA) Molecular insights into NRTI inhibition and mitochondrial toxicity revealed from a structural model of the human mitochondrial DNA polymerase R.J. Bienstock, W.C. Copeland (USA) Oxidative stress and mitochondrial DNA repair: implications for NRTIs induced DNA damage K. Hashiguchi, V.A. Bohr, N.C. de Souza-Pinto (USA) Mitochondrial membrane permeabilization by HIV-1 Vpr A. Deniaud, C. Brenner, G. Kroemer (France) Impact of mitochondrial regulation of apoptosis on the pathogenesis and treatment of HIV-1-induced immunodeficiency E.J. Buenz, A.D. Badley (USA) HIV-1 triggers mitochondrion death D. Arnoult, L. Viollet, F. Petit, J.-D. Lelie`vre, J. Estaquier (USA, France) Mitochondrial membrane potential and nucleosidic inhibitors of HIV reverse transcriptase: a cytometric approach R. Ferraresi, L. Troiano, D. Rossi, E. Gualdi, E. Lugli, C. Mussini, A. Cossarizza (Italy)
271
Calendar of Events
279
Guide for Authors
281
185 193
203 215 223 235 255
No. 4, August 2004 Invited review The machinery of mitochondrial fusion, division, and distribution, and emerging connections to apoptosis K.G. Hales (USA)
285
Regular papers MitoMorphy: an alignment and annotation tool for human mitochondrial DNA polymorphisms V. Ravichandran, R.D. Sriram, G.L. Gilliland (USA) Analysis of factors shaping codon usage in the mitochondrion genome of Oryza sativa Q. Liu, Y. Feng, Q. Xue (China) Accumulation of homoplasmic mtDNA point mutations in erythroblasts isolated from the bone marrow of patients with refractory anemia with ring sideroblasts (RARS) E. Babusˇiakova´, D. Vyoral, R. Neuwirtova´, M. Sˇisˇkova´, J. Zeman, S. Kmoch (Czech Republic) Terminal oxidation and the effects of zinc in prostate versus liver mitochondria L.C. Costello, Z. Guan, B. Kukoyi, P. Feng, R.B. Franklin (USA)
331
Editorial comment Citrate sours the malignant intent of prostate epithelia O. Bagasra (USA)
339
Calendar of Events
343
Guide for Authors
345
309 313
321
Volume contents
817
Nos. 5–6, September 2004 Special Issue: Mitochondrial Medicine - Developing the Scientific Basis to Medical Management of Mitochondrial Disease Guest Editor: Robert K. Naviaux Introduction R.K. Naviaux (USA) Diagnosis and Management Developing a systematic approach to the diagnosis and classification of mitochondrial disease R.K. Naviaux (USA) Respiratory chain enzyme analysis in muscle and liver D.R. Thorburn, C.W. Chow, D.M. Kirby (Australia) Oxidative phosphorylation analysis: assessing the integrated functional activity of human skeletal muscle mitochondria—case studies M.A. Puchowicz, M.E. Varnes, B.H. Cohen, N.R. Friedman, D.S. Kerr, C.L. Hoppel (USA) Respiratory chain analysis of skin fibroblasts in mitochondrial disease J.M. Cameron, V. Levandovskiy, N. MacKay, B.H. Robinson (Canada) Biochemical examination of fibroblasts in the diagnosis and research of oxidative phosphorylation (OXPHOS) defects L.P. van den Heuvel, J.A. Smeitink, R.J.T. Rodenburg (The Netherlands) Molecular analysis for mitochondrial DNA disorders S. Shanske, L.-J.C. Wong (USA) Immunological approaches to the characterization and diagnosis of mitochondrial disease R.A. Capaldi, J. Murray, L. Byrne, M.S. Janes, M.F. Marusich (USA) The problem of interlab variation in methods for mitochondrial disease diagnosis: enzymatic measurement of respiratory chain complexes F.N. Gellerich, J.A. Mayr, S. Reuter, W. Sperl, S. Zierz (Germany) Pathology of skeletal muscle in mitochondrial disorders J.M. Bourgeois, M.A. Tarnopolsky (Canada) Gene expression profiling in mitochondrial disease: assessment of microarray accuracy by high-throughput Q-PCR K.B. Beckman, K.Y. Lee, T. Golden, S. Melov (USA) Neuroimaging of mitochondrial disorders R. Haas, R. Dietrich (USA) In vivo magnetic resonance spectroscopy in the evaluation of mitochondrial disorders F. Arias-Mendoza (USA) The neurological presentations of childhood and adult mitochondrial disease: established syndromes and phenotypic variations A.L. Gropman (USA) Metabolomic approaches to mitochondrial disease: correlation of urine organic acids B.A. Barshop (USA) Exercise testing as a diagnostic entity in mitochondrial myopathies M. Tarnopolsky (Canada) Surgical and anesthetic management of patients with mitochondrial dysfunction J.L. Edmonds Jr. (USA) Physical, occupational, respiratory, speech, equine and pet therapies for mitochondrial disease T.J. Millhouse-Flourie (USA) Mitochondrial signal transduction in accelerated wound and retinal healing by near-infrared light therapy J.T. Eells, M.T.T. Wong-Riley, J. VerHoeve, M. Henry, E.V. Buchman, M.P. Kane, L.J. Gould, R. Das, M. Jett, B.D. Hodgson, D. Margolis, H.T. Whelan (USA) Mechanisms of action of light therapy for stroke and acute myocardial infarction J. Streeter, L. De Taboada, U. Oron (USA, Israel) Biology and Pathogenesis Mitochondrial dysfunction in reproduction R.P.S. Jansen, G.J. Burton (Australia, UK) Gastrointestinal complications of mitochondrial disease X.B. Hom, J.E. Lavine (USA) Mitochondrial dysfunction in liver disease and organ transplantation T. Hassanein (USA)
349
351 363 377 387 395 403 417
427 441 453 471 491 503 521 529 543 549
559 569
577 601 609
818
Volume contents
Mitochondrial dysfunction and heart disease P. Rosenberg (USA) Mitochondrial dysfunction in chronic ischemia and peripheral vascular disease G.J. Kemp (UK) Mitochondrial dysfunction and possible treatments in Parkinson’s disease—a review C.W. Shults (USA) Mitochondria as a primary target for vascular hypoperfusion and oxidative stress in Alzheimer’s disease G. Aliev, M.A. Smith, J.C. de la Torre, G. Perry (USA) The pathophysiology of stroke in mitochondrial disorders D.J. Michelson, S Ashwal (USA) Mitochondrial dysfunction in hearing loss N. Fischel-Ghodsian, R.D. Kopke, X. Ge (USA) The structure–function correlates of mammalian rod and cone photoreceptor mitochondria: observations and unanswered questions G.A. Perkins, M.H. Ellisman, D.A. Fox (USA) Mitochondrial damage and dysfunction in traumatic brain injury J. Lifshitz, P.G. Sullivan, D.A. Hovda, T. Wieloch, T.K. McIntosh (USA, Sweden) Mitochondrial dysfunction in osteoarthritis F.J. Blanco, M.J. Lo´pez-Armada, E. Maneiro (Spain) Mitochondrial dysfunction in septic shock and multiple organ dysfunction syndrome E.D. Crouser (USA) Mitochondria and autoimmunity in primary biliary cirrhosis Y. Ichiki, P.S.C. Leung, H. Ishibashi, R.L. Coppel, A.A. Ansari, M.E. Gershwin (USA, Japan, Australia) Mitochondrial dysfunction in cancer J.S. Modica-Napolitano, K.K. Singh (USA) Mitochondrial dysfunction in AIDS and its treatment M. Gerschenson, K. Brinkman (USA, The Netherlands) Cellular redox poise modulation; the role of coenzyme Q10, gene and metabolic regulation A.W. Linnane, H. Eastwood (Australia) An evolutionary perspective on pathogenic mtDNA mutations: haplogroup associations of clinical disorders C. Herrnstadt, N. Howell (USA)
621 629 641 649 665 675 695 705 715 729 743 755 763 779 791
History The many faces of mitochondrial diseases S. DiMauro (USA)
799
Calendar of Events
809
Guide for Authors
811
Volume Contents
815
Keyword Index
819
Author Index
821
Contents of volume 4 No. 1, June 2004 Regular papers Import and orientation of the MWFE protein in mitochondrial NADH-ubiquinone oxidoreductase N. Yadava, I.E. Scheffler (USA) Absence of accessory subunit in the DNA polymerase g purified from yeast mitochondria P. Lucas, J.-P. Lasserre, J. Plissonneau, M. Castroviejo (France) Interaction of mitochondrial elongation factor Tu with aminoacyl-tRNAs S.E. Hunter, L.L. Spremulli (USA) Erythromycin as a potential precipitating agent in the onset of Leber’s hereditary optic neuropathy C.C. Luca, B.L. Lam, C.T. Moraes (USA) Pitfalls in restriction fragment length polymorphism analysis of Leber’s hereditary optic neuropathy patients F. Carrara, P.F. Chinnery, P.Y.W. Man, M. Zeviani, V. Tiranti (Italy, UK) Pathogenicity of missense mutations in SURF1 deficiency inducing the Leigh syndrome. Importance in diagnosis A. Dubot, E. Hervouet, G. Mandon, M.T. Zabot, C. Godinot (France) Higher respiratory rates and improved creatine stimulation in brain mitochondria isolated with anti-oxidants G.J. Brewer, T.T. Jones, T. Wallimann, U. Schlattner (USA, Switzerland) Abstracts Abstracts from ‘Mitochondrial Medicine 2004’ 4–7 August, 2004, Pittsburgh, PA, USA Abstract index
59 83
Calendar of Events
87
Guide for Authors
89
1 13 21 31 37 41 49
Nos. 2–3, July 2004 Special Issue: Mitochondria, HIV and Antiretroviral Therapy Guest Editor: M. Gerschenson Foreword M. Gerschenson (USA) Clinical Mitochondrial injury in the pathogenesis of antiretroviral-induced hepatic steatosis and lactic acidemia L. Day, C. Shikuma, M. Gerschenson (USA) Role of mitochondria in HIV lipoatrophy: insight into pathogenesis and potential therapies G.A. McComsey, U.A. Walker (USA, Germany) HIV-associated dementia, mitochondrial dysfunction, and oxidative stress V. Valcour, B. Shiramizu (USA) HIV neuromuscular disease and mitochondrial function L. Estanislao, D. Thomas, D. Simpson (USA) Cardiomyopathy, nucleoside reverse transcriptase inhibitors and mitochondria are linked through AIDS and its therapy W. Lewis (USA)
93
95 111 119 131 141
816
Volume contents
HIV-associated mitochondrial toxicity in pregnancy L.E. Kamemoto, B. Shiramizu, M. Gerschenson (USA) l-Carnitine and acetyl-l-carnitine in the treatment of complications associated with HIV infection and antiretroviral therapy I. Ilias, I. Manoli, M.R. Blackman, P.W. Gold, S. Alesci (USA, Greece) HIV disease progression and limited antiretroviral treatment options for a HIV-1 infected individual with myoclonic epilepsy associated with ragged red fibers E.J. Walsh, S. Souza, M. Gerschenson, C. Shikuma, D. Chow (USA) Cumulative insults to mitochondrial function may promote the emergence of ‘syndrome X’ and diabetes mellitus in HIV/HCV co-infected patients M.P. Revuelta (USA)
153 163
169
175
Basic Science Potential roles for uncoupling proteins in HIV lipodystrophy D. Nolan, C. Pace (Australia) Direct effects of nucleoside reverse transcriptase inhibitors on rat cardiac mitochondrial bioenergetics K.C. Lund, K.B. Wallace (USA) Molecular insights into NRTI inhibition and mitochondrial toxicity revealed from a structural model of the human mitochondrial DNA polymerase R.J. Bienstock, W.C. Copeland (USA) Oxidative stress and mitochondrial DNA repair: implications for NRTIs induced DNA damage K. Hashiguchi, V.A. Bohr, N.C. de Souza-Pinto (USA) Mitochondrial membrane permeabilization by HIV-1 Vpr A. Deniaud, C. Brenner, G. Kroemer (France) Impact of mitochondrial regulation of apoptosis on the pathogenesis and treatment of HIV-1-induced immunodeficiency E.J. Buenz, A.D. Badley (USA) HIV-1 triggers mitochondrion death D. Arnoult, L. Viollet, F. Petit, J.-D. Lelie`vre, J. Estaquier (USA, France) Mitochondrial membrane potential and nucleosidic inhibitors of HIV reverse transcriptase: a cytometric approach R. Ferraresi, L. Troiano, D. Rossi, E. Gualdi, E. Lugli, C. Mussini, A. Cossarizza (Italy)
271
Calendar of Events
279
Guide for Authors
281
185 193
203 215 223 235 255
No. 4, August 2004 Invited review The machinery of mitochondrial fusion, division, and distribution, and emerging connections to apoptosis K.G. Hales (USA)
285
Regular papers MitoMorphy: an alignment and annotation tool for human mitochondrial DNA polymorphisms V. Ravichandran, R.D. Sriram, G.L. Gilliland (USA) Analysis of factors shaping codon usage in the mitochondrion genome of Oryza sativa Q. Liu, Y. Feng, Q. Xue (China) Accumulation of homoplasmic mtDNA point mutations in erythroblasts isolated from the bone marrow of patients with refractory anemia with ring sideroblasts (RARS) E. Babusˇiakova´, D. Vyoral, R. Neuwirtova´, M. Sˇisˇkova´, J. Zeman, S. Kmoch (Czech Republic) Terminal oxidation and the effects of zinc in prostate versus liver mitochondria L.C. Costello, Z. Guan, B. Kukoyi, P. Feng, R.B. Franklin (USA)
331
Editorial comment Citrate sours the malignant intent of prostate epithelia O. Bagasra (USA)
339
Calendar of Events
343
Guide for Authors
345
309 313
321
Volume contents
817
Nos. 5–6, September 2004 Special Issue: Mitochondrial Medicine - Developing the Scientific Basis to Medical Management of Mitochondrial Disease Guest Editor: Robert K. Naviaux Introduction R.K. Naviaux (USA) Diagnosis and Management Developing a systematic approach to the diagnosis and classification of mitochondrial disease R.K. Naviaux (USA) Respiratory chain enzyme analysis in muscle and liver D.R. Thorburn, C.W. Chow, D.M. Kirby (Australia) Oxidative phosphorylation analysis: assessing the integrated functional activity of human skeletal muscle mitochondria—case studies M.A. Puchowicz, M.E. Varnes, B.H. Cohen, N.R. Friedman, D.S. Kerr, C.L. Hoppel (USA) Respiratory chain analysis of skin fibroblasts in mitochondrial disease J.M. Cameron, V. Levandovskiy, N. MacKay, B.H. Robinson (Canada) Biochemical examination of fibroblasts in the diagnosis and research of oxidative phosphorylation (OXPHOS) defects L.P. van den Heuvel, J.A. Smeitink, R.J.T. Rodenburg (The Netherlands) Molecular analysis for mitochondrial DNA disorders S. Shanske, L.-J.C. Wong (USA) Immunological approaches to the characterization and diagnosis of mitochondrial disease R.A. Capaldi, J. Murray, L. Byrne, M.S. Janes, M.F. Marusich (USA) The problem of interlab variation in methods for mitochondrial disease diagnosis: enzymatic measurement of respiratory chain complexes F.N. Gellerich, J.A. Mayr, S. Reuter, W. Sperl, S. Zierz (Germany) Pathology of skeletal muscle in mitochondrial disorders J.M. Bourgeois, M.A. Tarnopolsky (Canada) Gene expression profiling in mitochondrial disease: assessment of microarray accuracy by high-throughput Q-PCR K.B. Beckman, K.Y. Lee, T. Golden, S. Melov (USA) Neuroimaging of mitochondrial disorders R. Haas, R. Dietrich (USA) In vivo magnetic resonance spectroscopy in the evaluation of mitochondrial disorders F. Arias-Mendoza (USA) The neurological presentations of childhood and adult mitochondrial disease: established syndromes and phenotypic variations A.L. Gropman (USA) Metabolomic approaches to mitochondrial disease: correlation of urine organic acids B.A. Barshop (USA) Exercise testing as a diagnostic entity in mitochondrial myopathies M. Tarnopolsky (Canada) Surgical and anesthetic management of patients with mitochondrial dysfunction J.L. Edmonds Jr. (USA) Physical, occupational, respiratory, speech, equine and pet therapies for mitochondrial disease T.J. Millhouse-Flourie (USA) Mitochondrial signal transduction in accelerated wound and retinal healing by near-infrared light therapy J.T. Eells, M.T.T. Wong-Riley, J. VerHoeve, M. Henry, E.V. Buchman, M.P. Kane, L.J. Gould, R. Das, M. Jett, B.D. Hodgson, D. Margolis, H.T. Whelan (USA) Mechanisms of action of light therapy for stroke and acute myocardial infarction J. Streeter, L. De Taboada, U. Oron (USA, Israel) Biology and Pathogenesis Mitochondrial dysfunction in reproduction R.P.S. Jansen, G.J. Burton (Australia, UK) Gastrointestinal complications of mitochondrial disease X.B. Hom, J.E. Lavine (USA) Mitochondrial dysfunction in liver disease and organ transplantation T. Hassanein (USA)
349
351 363 377 387 395 403 417
427 441 453 471 491 503 521 529 543 549
559 569
577 601 609
818
Volume contents
Mitochondrial dysfunction and heart disease P. Rosenberg (USA) Mitochondrial dysfunction in chronic ischemia and peripheral vascular disease G.J. Kemp (UK) Mitochondrial dysfunction and possible treatments in Parkinson’s disease—a review C.W. Shults (USA) Mitochondria as a primary target for vascular hypoperfusion and oxidative stress in Alzheimer’s disease G. Aliev, M.A. Smith, J.C. de la Torre, G. Perry (USA) The pathophysiology of stroke in mitochondrial disorders D.J. Michelson, S Ashwal (USA) Mitochondrial dysfunction in hearing loss N. Fischel-Ghodsian, R.D. Kopke, X. Ge (USA) The structure–function correlates of mammalian rod and cone photoreceptor mitochondria: observations and unanswered questions G.A. Perkins, M.H. Ellisman, D.A. Fox (USA) Mitochondrial damage and dysfunction in traumatic brain injury J. Lifshitz, P.G. Sullivan, D.A. Hovda, T. Wieloch, T.K. McIntosh (USA, Sweden) Mitochondrial dysfunction in osteoarthritis F.J. Blanco, M.J. Lo´pez-Armada, E. Maneiro (Spain) Mitochondrial dysfunction in septic shock and multiple organ dysfunction syndrome E.D. Crouser (USA) Mitochondria and autoimmunity in primary biliary cirrhosis Y. Ichiki, P.S.C. Leung, H. Ishibashi, R.L. Coppel, A.A. Ansari, M.E. Gershwin (USA, Japan, Australia) Mitochondrial dysfunction in cancer J.S. Modica-Napolitano, K.K. Singh (USA) Mitochondrial dysfunction in AIDS and its treatment M. Gerschenson, K. Brinkman (USA, The Netherlands) Cellular redox poise modulation; the role of coenzyme Q10, gene and metabolic regulation A.W. Linnane, H. Eastwood (Australia) An evolutionary perspective on pathogenic mtDNA mutations: haplogroup associations of clinical disorders C. Herrnstadt, N. Howell (USA)
621 629 641 649 665 675 695 705 715 729 743 755 763 779 791
History The many faces of mitochondrial diseases S. DiMauro (USA)
799
Calendar of Events
809
Guide for Authors
811
Volume Contents
815
Keyword Index
819
Author Index
821