i. steroid Biockm. Vol. 33, No. 2, pp. 315-317, 1989 Maxwell Pergamon MacmiIIanpk. Printed in Great Britain.
BOOK REVIEWS
Advances in Steroid Analysis ‘87-Proceedings of the 3rd Symposium on the Analysis of Steroids (Sopron, Hungary, 20-22 October 1987). Edited bv S. GOROG.Publish~ 1988 by Akademiai Kiado, Budapes;. No. of pages: 586---ISBN: 963-05-5229-9. This volume presents the Proceedings of the 3rd Symposium on the Analysis of Steroids, held in Sopron, Hungary, on 20-22 October 1987. The 73 papers included have been written by leading experts from 1S countries and represent the ove~helming majority of the lectures and posters presented at the meeting. Almost all important fields of contemporary steroid analysis are well represented, such as clinical analysis (dete~ination of steroid hormones, bile acids, sterols, vitamins D in various biological samples, protein binding and receptor studies), steroid analysis in veterinary medicine, food analysis, industrial and regulatory pharmaceutical analysis, and determination of steroids, such as digitals glycosides and ecdysones, in plants. This book contains up-to-date information on the most advanced methodology for the evaluation of steroid hormones. We now know the very important aspects of the technology in order to assess the ~n~ntratio~ of steroid hormones in different biological fluids and target tissues. The main chapters are as follows: -Protein binding and receptor binding studies -1mmunoassays: -General; -Radioimmunoassay; -Enzyme immunoassay; chromatography: -Gas chromatography; -Gas chromatography-mass spectrometry; -High-performance liquid chromato~aphy; -Thin-layer chromatography; -Clinical applications; -Miscellaneous. This book would be very useful for people working in general endocrinology, clinical laboratories, gynecology, obstetrics and cancer.
-Nerve regeneration; -Positional information and regulation during regeneration; -Proliferation and differentiation during evertebrate regeneration (special aspects). This book would be very useful for people working in biophysics, molecular biology, biology, physiology and for advanced students.
Hormones and Their Actiona Part I. Edited by B. A. COOKE, R. J. B. KINGand J. H. VANDERMOLEN. New Comprehemive ~~~~s~, %I. 18A. ~blish~ 1988 by Elsevier, Amsterdam. No. of pages: 294-ISBN: O-~-8~96-1 (pt. 1). This book contains up-to-date information concerning different aspects of hormone action which includes the control of the biosynthesis of different mechanisms of action for both steroid hormones and polypeptides. The main topics covered are as follows: General Aspects of Hormones and Hormone Actions: --The biosynthesis of steroid hormones: an update; --Overview of molecular aspects of steroid hormone actions; -Gene regulation by steroid hormones; --Characterization, assay and purification of steroid receptors; -Mechanism of action of thyroid hormone; -Metabolism of thyroid hormone; -Characterization of membrane receptors: some general considerations; -Metabolism and intracellular processing of protein hormones; -Internalization of peptide hormones and hormone receptors; -Physiological aspects of luteinizing hormone releasing factor and sex steroid actions: the interrelationship of agonist and antagonist activities; Specific Actions of Steroid Hormones:
Control of Ceil ~otifern~on and D~e~tia~~ During Regeneration. Edited by H. J. ANTON.Monographs in Developmental Biology, Vol. 21. published 1988 by Karger, Base1 (Switzerland). No. of pages: 246ISBN: 3-8055-473% 4. Retail price at January 1989: SFr 22l.OO/DM 26S.~/US%l47.5O/f100.50. One of the most important problems in biology is the regeneration of cells, not only during embryonic life but also during eel1 states: physiological and pathophysiological. Gene expression during individual life results not only in embryonic and ~stemb~onic development, but also in the preservation of shape, function, and physiological activity of all body parts of an individual, The higher a species has developed during evolution, the more time a fertilized egg requires to realize the genetically determined patterns during ontogenesis. The following main chapters are included in this volume: --Control of proliferation differentiation; -Muscle regeneration;
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-The functions of testosterone and its metabolites; -0estrogen actions; -Glucocorticoid receptor actions; -Progesterone action and receptors; -The pleiotropic vitamin D hormone. This book would be very useful for people working in endocrinology, molecular biology, molecular endocrinology, biology, biochemistry and for advanced students.
Methods in Enzymology. Editors-in-Chief: John N. Abelson and Melvin 1. Simon. Vol. 154: R~~~~t DNA-Port E, Edited by RAYWU and LAWRENCE GROSMAN. Published 1987 by Academic Press Inc., San Diego. No. of pages: 58O-ISBN: O-12-182055-6. Retail price as at December 1988: $66.00. In the last twenty years there has been an enormous advance in the knowledge of the genes, particularly in isolation and the obtention of regulatory regions of the genes to modify cell activity.