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Digestive System. Monographs on Pathology of Laboratory Animals
The only shortcoming - at least for those basically interested in plant toxins - seems to be a lack of information about the general biological significance, as well as some information about the medical importance, of poisonous vascular plants, which, based on statistics of European poison units and toxicological information centres, could possibly be incorporated in the introductory chapter in a further edition. In summary, the book is as concise as it is helpful for all those basically involved in the toxicology of plants . J. MEIER KNoEFEL, P. K. Felice Fontana - Life and Works, 422 pp . Trento, Italy: Società di Studi Trentini di Science Storiche (1984) . ARE You interested in the history of science and do you like to see the man behind his work? Then enjoy this outstanding contribution on Felice Fontana, the most well-known pioneer in early snake venom research besides Francesco Redi . The book was written by our member P. Knoefel, retired professor in pharmacology, and may be ordered from the above mentioned address. J. MEIER JoNEs, T. C., MoHR, U ., HUNT, R. D. (Eds) Digestive System . Monographs on Pathology of Laboratory Animals . 368 pp . Berlin : Springer (1985) . PUBLISHED as the 3rd volume of a set prepared under the sponsorship of the International Life Science Institute, this book covers the pathology of the digestive system in those laboratory animals most commonly used. Each part of the digestive system is introduced with a chapter on anatomical, histological and ultrastructural characteristics of the respective organs and tissues, followed by descriptions of the possible pathologic lesions . Special reference is given to precise and unambiguous identification of those pathologic features that are particularly useful for definite diagnosis, as well as to the problems arising in differential diagnosis. Notes on biologic features, comparison with other species and a reference list on the most important pertinent literature complete each part . Special attention is given to the illustrations: 352 excellent light and electron micrographs support the written word in an impressive way. J. MEIER WILLIAMSON, J. The Marine Stinger Book. Brisbane : Courier Mail Printing (1985) .
THIS IS one of the finest little books on the immediate or fn-st-aid treatment of marine animal stings that has yet been published. Although written specifically for the problem in Australian waters, the data and advice have world-wide application. The layout is excellent, the photographs superb and while thedescription of the injuries is short, it is quite adequate for the primary case of the injured patient . I thoroughly recommend this little text .
F. E. RUSSELL ANDERS, M . W. (Ed.) Bioactivation of FOreiRn Compounds . New York : Academic Press (1985) . METABOLIC conversion of drugs and chemicals is a well accepted mechanism for detoxification and excretion of these compounds. However, the same mechanisms may be responsible for the desired conversion of drugs into active metabolites or the undesired effect that chemicals are metabolized to highly toxic products. The current book, the 4th in a series of monographs on biochemical pharmacology, provides a good overview of a fast growing area. The first part reviews general aspects (history, pharmaeokinetics and cellular defence mechanisms), whereas the second part specifically deals with bioactivation of individual compounds. Thereader will find it very helpful that part II is subdivided according to chemical classes and that each chapter incorporates a comprehensive bibliography . Chapter 2, with a meagre I1 references, is the only exception, which is the more unfortunate as pharmacokinetics deserves much more attention than is currently devoted to it by most scientists in the field. Like many other multi-author books, the present volume has some minor inconsistencies in quality and style of the different chapters . However, these are by far outweighed by the competence and wealth of information which only researchers directly involved in the area can provide. H.-O. HOPPEN BRONSTEHN, A. C., RUSSELL, F. E., SULLIVAN, J. B., EUEN, N. B. and RumAclt, B. R. (Rocky Mountain Poison and Drug Center, Denver, CO 80204, and University of Arizona, Tucson, AZ 85721, U .S .A.) Negative pressure suction in field treatment of rattlesnake bite. Yet. Hum. Toxic . 28, 297 (1985) .
THIS IS one of the finest little books on the immediate or fn-st-aid treatment of marine animal stings that has yet been published. Although written specifically for the problem in Australian waters, the data and advice have world-wide application. The layout is excellent, the photographs superb and while thedescription of the injuries is short, it is quite adequate for the primary case of the injured patient . I thoroughly recommend this little text .
F. E. RUSSELL ANDERS, M . W. (Ed.) Bioactivation of FOreiRn Compounds . New York : Academic Press (1985) . METABOLIC conversion of drugs and chemicals is a well accepted mechanism for detoxification and excretion of these compounds. However, the same mechanisms may be responsible for the desired conversion of drugs into active metabolites or the undesired effect that chemicals are metabolized to highly toxic products. The current book, the 4th in a series of monographs on biochemical pharmacology, provides a good overview of a fast growing area. The first part reviews general aspects (history, pharmaeokinetics and cellular defence mechanisms), whereas the second part specifically deals with bioactivation of individual compounds. Thereader will find it very helpful that part II is subdivided according to chemical classes and that each chapter incorporates a comprehensive bibliography . Chapter 2, with a meagre I1 references, is the only exception, which is the more unfortunate as pharmacokinetics deserves much more attention than is currently devoted to it by most scientists in the field. Like many other multi-author books, the present volume has some minor inconsistencies in quality and style of the different chapters . However, these are by far outweighed by the competence and wealth of information which only researchers directly involved in the area can provide. H.-O. HOPPEN BRONSTEHN, A. C., RUSSELL, F. E., SULLIVAN, J. B., EUEN, N. B. and RumAclt, B. R. (Rocky Mountain Poison and Drug Center, Denver, CO 80204, and University of Arizona, Tucson, AZ 85721, U .S .A.) Negative pressure suction in field treatment of rattlesnake bite. Yet. Hum. Toxic . 28, 297 (1985) .