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EARLY DIAGNOSIS PROGRAM FOR ORAL POTENTIALLY MALIGNANT DISORDERS AND ORAL CANCER IN A CHRONIC ALCOHOLICS AND DRUG USERS
ORAL AND MAXILLOFACIAL PATHOLOGY e156 Abstracts basic health care for the occurrence of orofacial clefts in a city of northeastern Brazil. This was a census descriptive study applied through a questionnaire, which involved 96% of these professionals, and investigated clinical experience, professional training, basic knowledge about the clefts and experience in attendance to patients and profile of oral health care provided to patients. The results showed that the majority of participants have professional experience and performance in the public service, however, only 26% had some experience in attendance to patients with this malformation. It was observed that there is lack of knowledge on the subject and of information about the existence of multidisciplinary institutions which provide specialized care, revealing unpreparedness in attendance and lack of regulation for other levels of care in the county and state. It is suggested the need to adequate to the municipal health service to ensure the access of these patients, through greater approach about the subject, both in educational institutions of these professionals, such as through training.
RP148 - THE ROLE OF COMPUTED TOMOGRAPHY IN THE MANAGEMENT OF ORAL SQUAMOUS CELL CARCINOMA. TESSA DE LUCENA BOTELHO, ELISMAURO FRANCISCO DE MENDONÇA. The aim of this research was to evaluate the role of computed tomography (CT) as a complement for staging and determining the treatment plan related to squamous cell carcinoma in the oral cavity. A retrospective study on 298 patients was conducted, data about general aspects of the cancer, image examination and treatment were obtained by reviewing the patient’s medical records. The CT was employed in 106 of 298 patients evaluated. About of CT indication 76% was made before the start of management and 34% has been required as a complementary source for the diagnosis or for recurrent tumors evaluation. About the anatomical site of tumors, 79.3% of the palate’s cancer had been evaluated by CT, while only 24%-26.2% of the floor of the mouth and tongue cases had the indication of this complementary image exam. 39.7% of the cases with CT indication presented T4 index, similar as T2 index with 38.1%. The primary site of the oral squamous cell carcinoma has been demonstrated great influence on the indication of the CT and it has been employed mainly in tumors with difficult access locations. The initial clinic stage of the tumor did not influenced in the CT requirement.
RP149 - IMPLICATIONS OF ORAL CONDITIONS IN QUALITY OF LIFE AT HEAD AND NECK CANCER PATIENTS. ELAINE CATARINA DE CAMARGO, ALICE ZELMANOWICZ. The incidence of head and neck cancer has increased and constitutes an international public health problem. Socio-demographic and clinical aspects of oral health in populations can help prevention and treatment of the disease. This study proposed to know the perception of health and illness as an individual and subjective experience. It was applied 1 dental indicator and other questionnaire for evaluating socio-demographic and clinical characteristics of the sample. This cross-sectional study obtained the participation of 54 patients with a diagnosis of head and neck cancer, chosen by convenience from patients at oncology hospital. There was a predominance of males, mean age of 56 years, smokers, reduced socio, economic and educational status. The interval of time between perception to oncologic treatment access was, for the majority, over 18 months. The result of Oral Health Impact on Quality of Life (OHIP) test was “weak”. The population
OOOO August 2017 related problems on stomatognathic system and anyone participant received oral examination or dental care. The study concluded that the sample ignores the oral health implications on oncologic treatment and on their quality of life. Patient education and discussion of potential oral complications should be part of the pretreatment evaluation and of the complete cancer therapy.
RP150 - EARLY DIAGNOSIS PROGRAM FOR ORAL POTENTIALLY MALIGNANT DISORDERS AND ORAL CANCER IN A CHRONIC ALCOHOLICS AND DRUG USERS. DANIELA BRITO BASTOS, VITOR BONETTI VALENTE, BRUNA AMÉLIA MOREIRA SARAFIM DA SILVA, SUZY ELAINE NOBRE DE FREITAS, ANA RITA ALBUQUERQUE ZITO, EDER RICARDO BIASOLI, DANIEL GALERA BERNABE. To present the experience of a Brazilian program for early diagnosis of oral potentially malignant disorders and oral cancer in a chronic alcoholics and drugs abuse population treated at a specialized center. Here evaluated a total of 77 patients enrolled for alcoholism and drug abuse treatment during 1 year. Patients were investigated for medical history and addictions profile and extra and intraoral examinations were performed for oral potentially malignant disorders and oral cancer diagnosis. Most of the patients were male (91%) with a mean age of 45 years, white (56%) and had some neurological or psychiatric disorder (88%). All patients had at least 1 systemic disorder. 67 patients (87%) had smoking addiction and 53 patients (69%) had alcoholism addiction. 16 patients (21%) had some type of oral potentially malignant disorders such as leukoplakia (13%), erythroleukoplakia (4%) and actinic cheilitis (4%). Interestingly, 1 patient was diagnosed as tongue squamous cell carcinoma (T1N0M0). The patients were referred for treatment of oral lesions to our service. This program focused in a specific population with high risk for oral potentially malignant disorders and oral cancer development has promoted early diagnosis for alcohol and tobacco-related oral lesions.
RP151 - IMMUNOEXPRESSION OF KI-67, BCL2, EGFR AND CD57 IN THE SPECTRUM OF PERIRADICULAR CYSTS AND GRANULOMAS. WALTER ARTHUR SILVA VALENTE, FÁBIO RAMÔA PIRES, LUCIANA ARMADA DIAS. To comparatively analyze the expression of epidermal growth factor (EGF), the presence of natural killer cells (CD57+), epithelial proliferation (Ki-67) and bcl-2 expression in inflammatory periapical lesions (IPL) in different evolutional stages and showing different inflammatory profiles. The sample was composed by 52 IPL, including 22 periapical granulomas (PG) and 30 periapical cysts (PC), divided in 3 groups: PG, initial PC and advanced PC. Histologic and immunohistochemical analysis of all cases was performed and the results were compared among the 3 studied groups. There were no statistically significant differences regarding the expression of bcl-2, the presence of CD57+ and the expression of ki-67 comparing the 3 groups. The expression of EGF was more frequent in PC than in PG and the presence of CD57+ was more frequent in IPL with intense inflammatory infiltrate. There were no statistically significant differences when comparing the presence of CD57+, the expression of bcl-2 and the expression of EGF according with the type of inflammatory infiltrate and the type of epithelial lining from the PC. The results showed that the expression of EGF was more frequent in PC comparing with PG and that CD57+ were more frequent in IPL showing an intense inflammatory.
RP148 - THE ROLE OF COMPUTED TOMOGRAPHY IN THE MANAGEMENT OF ORAL SQUAMOUS CELL CARCINOMA. TESSA DE LUCENA BOTELHO, ELISMAURO FRANCISCO DE MENDONÇA. The aim of this research was to evaluate the role of computed tomography (CT) as a complement for staging and determining the treatment plan related to squamous cell carcinoma in the oral cavity. A retrospective study on 298 patients was conducted, data about general aspects of the cancer, image examination and treatment were obtained by reviewing the patient’s medical records. The CT was employed in 106 of 298 patients evaluated. About of CT indication 76% was made before the start of management and 34% has been required as a complementary source for the diagnosis or for recurrent tumors evaluation. About the anatomical site of tumors, 79.3% of the palate’s cancer had been evaluated by CT, while only 24%-26.2% of the floor of the mouth and tongue cases had the indication of this complementary image exam. 39.7% of the cases with CT indication presented T4 index, similar as T2 index with 38.1%. The primary site of the oral squamous cell carcinoma has been demonstrated great influence on the indication of the CT and it has been employed mainly in tumors with difficult access locations. The initial clinic stage of the tumor did not influenced in the CT requirement.
RP149 - IMPLICATIONS OF ORAL CONDITIONS IN QUALITY OF LIFE AT HEAD AND NECK CANCER PATIENTS. ELAINE CATARINA DE CAMARGO, ALICE ZELMANOWICZ. The incidence of head and neck cancer has increased and constitutes an international public health problem. Socio-demographic and clinical aspects of oral health in populations can help prevention and treatment of the disease. This study proposed to know the perception of health and illness as an individual and subjective experience. It was applied 1 dental indicator and other questionnaire for evaluating socio-demographic and clinical characteristics of the sample. This cross-sectional study obtained the participation of 54 patients with a diagnosis of head and neck cancer, chosen by convenience from patients at oncology hospital. There was a predominance of males, mean age of 56 years, smokers, reduced socio, economic and educational status. The interval of time between perception to oncologic treatment access was, for the majority, over 18 months. The result of Oral Health Impact on Quality of Life (OHIP) test was “weak”. The population
OOOO August 2017 related problems on stomatognathic system and anyone participant received oral examination or dental care. The study concluded that the sample ignores the oral health implications on oncologic treatment and on their quality of life. Patient education and discussion of potential oral complications should be part of the pretreatment evaluation and of the complete cancer therapy.
RP150 - EARLY DIAGNOSIS PROGRAM FOR ORAL POTENTIALLY MALIGNANT DISORDERS AND ORAL CANCER IN A CHRONIC ALCOHOLICS AND DRUG USERS. DANIELA BRITO BASTOS, VITOR BONETTI VALENTE, BRUNA AMÉLIA MOREIRA SARAFIM DA SILVA, SUZY ELAINE NOBRE DE FREITAS, ANA RITA ALBUQUERQUE ZITO, EDER RICARDO BIASOLI, DANIEL GALERA BERNABE. To present the experience of a Brazilian program for early diagnosis of oral potentially malignant disorders and oral cancer in a chronic alcoholics and drugs abuse population treated at a specialized center. Here evaluated a total of 77 patients enrolled for alcoholism and drug abuse treatment during 1 year. Patients were investigated for medical history and addictions profile and extra and intraoral examinations were performed for oral potentially malignant disorders and oral cancer diagnosis. Most of the patients were male (91%) with a mean age of 45 years, white (56%) and had some neurological or psychiatric disorder (88%). All patients had at least 1 systemic disorder. 67 patients (87%) had smoking addiction and 53 patients (69%) had alcoholism addiction. 16 patients (21%) had some type of oral potentially malignant disorders such as leukoplakia (13%), erythroleukoplakia (4%) and actinic cheilitis (4%). Interestingly, 1 patient was diagnosed as tongue squamous cell carcinoma (T1N0M0). The patients were referred for treatment of oral lesions to our service. This program focused in a specific population with high risk for oral potentially malignant disorders and oral cancer development has promoted early diagnosis for alcohol and tobacco-related oral lesions.
RP151 - IMMUNOEXPRESSION OF KI-67, BCL2, EGFR AND CD57 IN THE SPECTRUM OF PERIRADICULAR CYSTS AND GRANULOMAS. WALTER ARTHUR SILVA VALENTE, FÁBIO RAMÔA PIRES, LUCIANA ARMADA DIAS. To comparatively analyze the expression of epidermal growth factor (EGF), the presence of natural killer cells (CD57+), epithelial proliferation (Ki-67) and bcl-2 expression in inflammatory periapical lesions (IPL) in different evolutional stages and showing different inflammatory profiles. The sample was composed by 52 IPL, including 22 periapical granulomas (PG) and 30 periapical cysts (PC), divided in 3 groups: PG, initial PC and advanced PC. Histologic and immunohistochemical analysis of all cases was performed and the results were compared among the 3 studied groups. There were no statistically significant differences regarding the expression of bcl-2, the presence of CD57+ and the expression of ki-67 comparing the 3 groups. The expression of EGF was more frequent in PC than in PG and the presence of CD57+ was more frequent in IPL with intense inflammatory infiltrate. There were no statistically significant differences when comparing the presence of CD57+, the expression of bcl-2 and the expression of EGF according with the type of inflammatory infiltrate and the type of epithelial lining from the PC. The results showed that the expression of EGF was more frequent in PC comparing with PG and that CD57+ were more frequent in IPL showing an intense inflammatory.