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Erratum to “Acceleration of bone regeneration by local application of lithium: Wnt signal-mediated osteoblastogenesis and Wnt signal-independent suppression of osteoclastogenesis” [Biochem. Pharmacol. 90 (2014) 397–405]
Biochemical Pharmacology 91 (2014) 552–553
Contents lists available at ScienceDirect
Biochemical Pharmacology journal homepage: www.elsevier.com/locate/biochempharm
Erratum
Erratum to ‘‘Acceleration of bone regeneration by local application of lithium: Wnt signal-mediated osteoblastogenesis and Wnt signal-independent suppression of osteoclastogenesis’’ [Biochem. Pharmacol. 90 (2014) 397–405] Masaki Arioka a,b, Fumi Takahashi-Yanaga a,c,*, Masanori Sasaki b, Tatsuya Yoshihara a, Sachio Morimoto a, Masato Hirata d, Yoshihide Mori b, Toshiyuki Sasaguri a a
Department of Clinical Pharmacology, Faculty of Medical Sciences, Kyushu University, Fukuoka, Japan Department of Oral and Maxillofacial Surgery, Faculty of Dental Science, Kyushu University, Fukuoka, Japan c Global Medical Science Education Unit, Faculty of Medical Sciences, Kyushu University, Fukuoka, Japan d Department of Molecular and Cellular Biochemistry, Faculty of Dental Sciences, Kyushu University, Fukuoka, Japan b
Unfortunately when this paper was originally published, Fig. 4B was incorrect. The correct artwork is printed overleaf. We apologize for any inconvenience caused.
DOI of original article: http://dx.doi.org/10.1016/j.bcp.2014.06.011 * Corresponding author. E-mail address: [email protected] (F. Takahashi-Yanaga). http://dx.doi.org/10.1016/j.bcp.2014.08.012 0006-2952/ß 2014 Elsevier Inc. All rights reserved.
M. Arioka et al. / Biochemical Pharmacology 91 (2014) 552–553
553
Fig. 4. Effect of local application of Li2CO3 on injured bone. (A) Micro-CT images of the sagittal section of rat tibias on day 0 (left) and day 14 after surgery (right). Bone defects were induced and then local treatment was carried out with or without Li2CO3. Tibial bones were extracted and fixed at 14 days after surgery. Quantitative analysis of newly formed bone was performed by micro-CT. New bone volume/total bone volume (new BV/total BV) was calculated. Values are the means SD (n = 6). (B) Images of Villanueva staining of extracted tibias. The images are low magnification (left), natural (second left), polarization (second right), and fluorescence (right) views of the sections. Black square indicates the magnified area. Black arrows in the fluorescence view indicate the labeled thickness. Ec. F. Ar., endocortical formation area; Ia. Ct. Ar., intracortical area; Ex. Callus Ar., external callus area. (C) Histomorphometric analyses were performed using Villanueva-stained sections. New BV/TV, new bone volume/tissue volume; Lm. BV/new BV, lamellar bone volume/new bone volume; MAR, mineral apposition rate; N. Ob/new BV, number of osteoblasts/new bone volume; N. Oc/new BV, number of osteoclasts/new bone volume. Values are the means SD (n = 3). *P < 0.05, **P < 0.01 vs. control. (For interpretation of the references to color in this figure legend, the reader is referred to the web version of this article.)
Contents lists available at ScienceDirect
Biochemical Pharmacology journal homepage: www.elsevier.com/locate/biochempharm
Erratum
Erratum to ‘‘Acceleration of bone regeneration by local application of lithium: Wnt signal-mediated osteoblastogenesis and Wnt signal-independent suppression of osteoclastogenesis’’ [Biochem. Pharmacol. 90 (2014) 397–405] Masaki Arioka a,b, Fumi Takahashi-Yanaga a,c,*, Masanori Sasaki b, Tatsuya Yoshihara a, Sachio Morimoto a, Masato Hirata d, Yoshihide Mori b, Toshiyuki Sasaguri a a
Department of Clinical Pharmacology, Faculty of Medical Sciences, Kyushu University, Fukuoka, Japan Department of Oral and Maxillofacial Surgery, Faculty of Dental Science, Kyushu University, Fukuoka, Japan c Global Medical Science Education Unit, Faculty of Medical Sciences, Kyushu University, Fukuoka, Japan d Department of Molecular and Cellular Biochemistry, Faculty of Dental Sciences, Kyushu University, Fukuoka, Japan b
Unfortunately when this paper was originally published, Fig. 4B was incorrect. The correct artwork is printed overleaf. We apologize for any inconvenience caused.
DOI of original article: http://dx.doi.org/10.1016/j.bcp.2014.06.011 * Corresponding author. E-mail address: [email protected] (F. Takahashi-Yanaga). http://dx.doi.org/10.1016/j.bcp.2014.08.012 0006-2952/ß 2014 Elsevier Inc. All rights reserved.
M. Arioka et al. / Biochemical Pharmacology 91 (2014) 552–553
553
Fig. 4. Effect of local application of Li2CO3 on injured bone. (A) Micro-CT images of the sagittal section of rat tibias on day 0 (left) and day 14 after surgery (right). Bone defects were induced and then local treatment was carried out with or without Li2CO3. Tibial bones were extracted and fixed at 14 days after surgery. Quantitative analysis of newly formed bone was performed by micro-CT. New bone volume/total bone volume (new BV/total BV) was calculated. Values are the means SD (n = 6). (B) Images of Villanueva staining of extracted tibias. The images are low magnification (left), natural (second left), polarization (second right), and fluorescence (right) views of the sections. Black square indicates the magnified area. Black arrows in the fluorescence view indicate the labeled thickness. Ec. F. Ar., endocortical formation area; Ia. Ct. Ar., intracortical area; Ex. Callus Ar., external callus area. (C) Histomorphometric analyses were performed using Villanueva-stained sections. New BV/TV, new bone volume/tissue volume; Lm. BV/new BV, lamellar bone volume/new bone volume; MAR, mineral apposition rate; N. Ob/new BV, number of osteoblasts/new bone volume; N. Oc/new BV, number of osteoclasts/new bone volume. Values are the means SD (n = 3). *P < 0.05, **P < 0.01 vs. control. (For interpretation of the references to color in this figure legend, the reader is referred to the web version of this article.)