Exam 2: Incidence of Bleeding Following Invasive Procedures in Patients With Thrombocytopenia and Advanced Liver Disease

October 2010

CME ACTIVITIES

Exam 2: Incidence of Bleeding Following Invasive Procedures in Patients With Thrombocytopenia and Advanced Liver Disease Test ID No.: 0116

Contact Hours: 1.0

Expiration Date: October 31, 2011

Question 1: In the study by Giannini et al, what percentage of patients being evaluated for orthotopic liver transplantation had thrombocytopenia as defined by a platelet count ⬍150,000/␮L?

a. b. c. d.

25% 45% 65% 85%

a. b. c. d.

9% 19% 31% 47%

a. b. c. d.

0 2 4 6

a. b. c. d.

International normalized ratio (INR) ⬎1.5 Model for End-Stage Liver Disease (MELD) score Age None of the above

Question 2: What percentage of the 32 patients with severe thrombocytopenia as defined by a platelet count ⬍75,000/␮L had bleeding occur during an invasive procedure?

Question 3: How many of the 18 thrombocytopenic patients with platelet count ⬎75,000/␮L had bleeding occur during an invasive procedure?

Question 4: What other factor in the 32 patients with severe thrombocytopenia correlated with bleeding during an invasive procedure?

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