Exam 2: Liver Test Results Do Not Identify Liver Disease in Adults With α1-Antitrypsin Deficiency

CLINICAL GASTROENTEROLOGY AND HEPATOLOGY 2012;10:e94

Exam 2: Liver Test Results Do Not Identify Liver Disease in Adults With ␣1-Antitrypsin Deficiency Test ID No.: 0166

Contact Hours: 1.0

Expiration Date: November 30, 2013

Question 1. In adult ␣1-antitrypsin deficient patients without established liver disease or symptoms, regular assessment of simple liver function test is recommended.

a. True b. False

Question 2. In the study by Clark et al, the sensitivity of an alanine aminotransferase result above the upper limit of normal (⬎55 IU/mL for men and ⬎40 IU/mL for women) to detect the presence of any liver disease was approximately:

a. b. c. d.

12% 36% 64% 87%

Question 3. In individuals with ␣1-antitrypsin deficiency, lung disease and liver disease do not occur in the same patient.

a. True b. False

Question 4. Risk factors for the presence of liver disease in adults with ␣-1 antitrypsin deficiency include:

a. b. c. d.

Alcohol and tobacco use Diabetes and hypertension Male sex and childhood liver disease Age and alcohol use